Australian New Crops Info 2016
Supported by the Rural Industries Research and Development Corporation

Listing of Interesting Plants of the World:

Quillaja saponaria

 

 

This species is usually known as:

Quillaja saponaria

 

This species has no synonyms in The Plant List

 

Common names:

Soapbark, Soap Bark Tree

 

 

Trends (five databases) 1901-2013:
[Number of papers mentioning Quillaja saponaria: 994]

 

 

Popularity of Quillaja saponaria over time
[Left-hand Plot: Plot of numbers of papers mentioning Quillaja saponaria (histogram and left hand axis scale of left-hand plot) and line of best fit, 1901 to 2013 (equation and % variation accounted for in box); Right-hand Plot: Plot of a proportional micro index, derived from numbers of papers mentioning Quillaja saponaria as a proportion (scaled by multiplying by one million) of the approximate total number of papers available in databases for that year (frequency polygon and left-hand axis scale of right-hand plot) and line of best fit, 1901 to 2013 (equation and % variation accounted for in box)] 

[For larger charts showing the numbers of papers that have mentioned this species over years, select this link; there are links to come back from there]

 

Keywords

[Total number of keywords included in the papers that mentioned this species: 4492]

 

2 (1), saponins (117), Adjuvant (88), Quillaja saponaria (70), Adjuvants (61), Saponin (58), Vaccine (56), Iscoms (29), methane (25), vaccines (25), plant extracts (23), Antibody (20), Chile (19), Iscom (18), Carbohydrates (17), vaccination (17), Haemolysis (16), Rumen fermentation (14), Cholesterol (13), Quil A (13), Yucca schidigera (13), QS-21 (12), Quillaja saponaria Molina (12), Immunity (11), <ARROW Proliferation (11), Quillaja saponin (11), Subunit vaccine (11), Malaria (10), Cancer (9), Growth (9), Immune response (9), Immunomodulation (9), immunotherapy (9), Kala-azar (9), phytochemicals (9), Protozoa (9), quillaic acid (9), Adjuvanticity (8), Culex quinquefasciatus (8), Cytokines (8), Digestibility (8), Immune responses (8), Immunology (8), Liposomes (8), methane production (8), Mucosal immunity (8), QS21 (8), Quillaja saponins (8), bark (7), Canine visceral leishmaniasis (7), Cytotoxicity (7), Facilitation (7), feed additives (7), Glycosylation (7), immunization (7), immunostimulants (7), Internet resource (7), Leishmaniasis (7), Medicinal plants (7), Plant secondary compounds (7), Toxicity (7), Visceral leishmaniasis (7), ammonia (6), Antifungal activity (6), diabetes (6), DNA vaccine (6), essential oils (6), hepatitis B (6), In vitro (6), Innate immunity (6), ISCOM-Matrix (6), Mass Spectrometry (6), Mechanism (6), orthogonality (6), OVA (6), Quillaja (6), Rotavirus DOWN>(6), Tannins (6), Triterpenes (6), Triterpenoids (6), Tuberculosis (6), Biosurfactant (5), Cancer vaccine (5), central Chile (5), Cholera toxin (5), Crocus sativus (5), dairy cow (5), dairy cows (5), digestion (5), Fasciola hepatica (5), fragmentation (5), gas production (5), Glycoproteins (5), glycosides (5), Influenza vaccine (5), Leishmania chagasi (5), Leishmania donovani (5), Nanoparticles (5), Panax notoginseng (5), Plasmodium falciparum (5), Platycodon grandiflorum (5), Protection (5), QS21 saponin (5), Sheep (5)…..

 

[If all keywords are not here (as indicated by .....), they can be accessed from this link; there are links to come back from there]

 

 

Most likely scope for crop use/product (%):
[Please note: When there are only a few papers mentioning a species, care should be taken with the interpretation of these crop use/product results; as well, a mention may relate to the use of a species, or the context in which it grows, rather than a product]

 

poison (21.10), oilseed/fat (10.08), pseudocereal (9.65), starch (9.46), hemiparasite (5.58), nutraceutical (5.42), weed (4.83), timber (3.98), tannin (3.91), flavouring/spice (3.31)…..

 

[To see the full list of crop use/product outcomes, from searching abstracts of the papers that have mentioned this species, select this link; details of the analysis process have also been included; there are links to come back from there]

 

 

Recent mentions of this species in the literature:
[since 2012, with links to abstracts; The references from 1901-2013 which have been used for the trend, keyword and crop use/product analyses below, are listed below these references]

 

Alcázar M, Kind T, Gschaedler A, Silveria M, Arrizon J, Fiehn O, Vallejo A, Higuera I and Lugo E (2017) Effect of steroidal saponins from Agave on the polysaccharide cell wall composition of Saccharomyces cerevisiae and Kluyveromyces marxianus. LWT - Food Science and Technology 77, 430-439. http://www.sciencedirect.com/science/article/pii/S0023643816307204

Bartnik M and Facey PC (2017) Chapter 8 - Glycosides A2 - Badal, Simone. In Pharmacognosy. (Ed.^(Eds Delgoda R) pp. 101-161. (Academic Press: Boston). http://www.sciencedirect.com/science/article/pii/B9780128021040000081

Binks BP, Muijlwijk K, Koman H and Poortinga AT (2017) Food-grade Pickering stabilisation of foams by in situ hydrophobisation of calcium carbonate particles. Food Hydrocolloids 63, 585-592. http://www.sciencedirect.com/science/article/pii/S0268005X16305227

Böttcher S, Keppler JK and Drusch S (2017) Mixtures of Quillaja saponin and beta-lactoglobulin at the oil/water-interface: Adsorption, interfacial rheology and emulsion properties. Colloids and Surfaces A: Physicochemical and Engineering Aspects 518, 46-56. http://www.sciencedirect.com/science/article/pii/S0927775716310846

Chung C, Sher A, Rousset P and McClements DJ (2017) Use of natural emulsifiers in model coffee creamers: Physical properties of quillaja saponin-stabilized emulsions. Food Hydrocolloids 67, 111-119. http://www.sciencedirect.com/science/article/pii/S0268005X16308323

de Faria JT, de Oliveira EB, Minim VPR and Minim LA (2017) Performance of Quillaja bark saponin and β-lactoglobulin mixtures on emulsion formation and stability. Food Hydrocolloids 67, 178-188. http://www.sciencedirect.com/science/article/pii/S0268005X16304398

Didierlaurent AM, Berger A, Heineman TC, Henderickx V, Tavares Da Silva F, Vekemans J, Voss G and Garçon N (2017) Chapter 14 - The Development of the Adjuvant System AS01: A Combination of Two Immunostimulants MPL and QS-21 in Liposomes A2 - Schijns, Virgil E.J.C. In Immunopotentiators in Modern Vaccines (Second Edition). (Ed.^(Eds OHagan DT) pp. 265-285. (Academic Press). http://www.sciencedirect.com/science/article/pii/B9780128040195000141

Đorđević V, Belščak-Cvitanović A, Drvenica I, Komes D, Nedović V and Bugarski B (2017) 3 - Nanoscale nutrient delivery systems A2 - Grumezescu, Alexandru Mihai. In Nutrient Delivery. (Ed.^(Eds  pp. 87-139. (Academic Press). http://www.sciencedirect.com/science/article/pii/B9780128043042000032

Duarte MC, Lage DP, Martins VT, Costa LE, Carvalho AMRS, Ludolf F, Santos TTdO, Vale DL, Roatt BM, Menezes-Souza D, Fernandes AP, Tavares CAP and Coelho EAF (2017) A vaccine composed of a hypothetical protein and the eukaryotic initiation factor 5a from Leishmania braziliensis cross-protection against Leishmania amazonensis infection. Immunobiology 222, 251-260. http://www.sciencedirect.com/science/article/pii/S0171298516303825

Even M-P, Bobbala S, Gibson B, Hook S, Winter G and Engert J (2017) Twin-screw extruded lipid implants containing TRP2 peptide for tumour therapy. European Journal of Pharmaceutics and Biopharmaceutics 114, 79-87. http://www.sciencedirect.com/science/article/pii/S0939641116303289

Fuchs LI, Fort MC, Cano D, Bonetti CM, Giménez HD, Vázquez PM, Bacigalupe D, Breccia JD, Campero CM and Oyhenart JA (2017) Clearance of Tritrichomonas foetus in experimentally infected heifers protected with vaccines based on killed-T. foetus with different adjuvants. Vaccine 35, 1341-1346. http://www.sciencedirect.com/science/article/pii/S0264410X16312555

Gautam M, Patwardhan B, Gairola S and Jadhav S (2017) Chapter 11 - Vaccines and Immunodrugs Discovery. In Innovative Approaches in Drug Discovery. (Ed.^(Eds  pp. 315-341. (Academic Press: Boston). http://www.sciencedirect.com/science/article/pii/B9780128018149000118

Giordano G, Segal L, Prinsen M, Wijnands MVW, Garçon N and Destexhe E (2017) Non-clinical safety assessment of single and repeated administration of gE/AS01 zoster vaccine in rabbits. Journal of Applied Toxicology 37, 132-141. http://dx.doi.org/10.1002/jat.3329

Grabowska K, Podolak I, Galanty A, Żmudzki P, Koczurkiewicz P, Piska K, Pękala E and Janeczko Z (2017) Two new triterpenoid saponins from the leaves of Impatiens parviflora DC. and their cytotoxic activity. Industrial Crops and Products 96, 71-79. http://www.sciencedirect.com/science/article/pii/S092666901630766X

Guyader J, Eugčne M, Doreau M, Morgavi DP, Gérard C and Martin C (2017) Tea saponin reduced methanogenesis in vitro but increased methane yield in lactating dairy cows. Journal of Dairy Science 100, 1845-1855. http://www.sciencedirect.com/science/article/pii/S0022030217300462

Karunaratne DN, Surandika Siriwardhana DA, Ariyarathna IR, Indunil Rajakaruna RMP, Banu FT and Karunaratne V (2017) 17 - Nutrient delivery through nanoencapsulation A2 - Grumezescu, Alexandru Mihai. In Nutrient Delivery. (Ed.^(Eds  pp. 653-680. (Academic Press). http://www.sciencedirect.com/science/article/pii/B9780128043042000172

Leonti M, Stafford GI, Cero MD, Cabras S, Castellanos ME, Casu L and Weckerle CS (2017) Reverse ethnopharmacology and drug discovery. Journal of Ethnopharmacology 198, 417-431. http://www.sciencedirect.com/science/article/pii/S0378874116317846

Luo X, Zhou Y, Bai L, Liu F, Deng Y and McClements DJ (2017) Fabrication of β-carotene nanoemulsion-based delivery systems using dual-channel microfluidization: Physical and chemical stability. Journal of Colloid and Interface Science 490, 328-335. http://www.sciencedirect.com/science/article/pii/S0021979716309341

Martins VT, Duarte MC, Lage DP, Costa LE, Carvalho AMRS, Mendes TAO, Roatt BM, Menezes-Souza D, Soto M and Coelho EAF (2017) A recombinant chimeric protein composed of human and mice-specific CD4+ and CD8+ T-cell epitopes protects against visceral leishmaniasis. Parasite Immunology 39, n/a-n/a. http://dx.doi.org/10.1111/pim.12359

Morelli AB and Maraskovsky E (2017) Chapter 16 - ISCOMATRIX Adjuvant in the Development of Prophylactic and Therapeutic Vaccines A2 - Schijns, Virgil E.J.C. In Immunopotentiators in Modern Vaccines (Second Edition). (Ed.^(Eds OHagan DT) pp. 311-332. (Academic Press). http://www.sciencedirect.com/science/article/pii/B9780128040195000165

Muńoz-Wolf N, McCluskey S and Lavelle EC (2017) Chapter 2 - The Role of Inflammasomes in Adjuvant-Driven Humoral and Cellular Immune Responses A2 - Schijns, Virgil E.J.C. In Immunopotentiators in Modern Vaccines (Second Edition). (Ed.^(Eds OHagan DT) pp. 23-42. (Academic Press). http://www.sciencedirect.com/science/article/pii/B9780128040195000025

Nübling S, Hägele F, Wohlt D, Graf B, Schweiggert RM, Carle R, Schmidt H and Weiss A (2017) Effects of Quillaja saponaria extract and Nα-lauroyl-l-arginine ethyl ester on reducing selected foodborne pathogens in vitro and maintaining quality of fresh-cut endive (Cichorium endivia L.) at pilot plant scale. Food Control 73, Part B, 393-400. http://www.sciencedirect.com/science/article/pii/S095671351630456X

Pacholak A, Smułek W, Jesionowski T and Kaczorek E (2017) The ability of Achromobacter sp. KW1 strain to biodegrade isomers of chlorotoluene. Journal of Chemical Technology & Biotechnology, n/a-n/a. http://dx.doi.org/10.1002/jctb.5221

Shin WJ, Noh HJ, Noh Y-W, Kim S, Um SH and Lim YT (2017) Hyaluronic acid-supported combination of water insoluble immunostimulatory compounds for anti-cancer immunotherapy. Carbohydrate Polymers 155, 1-10. http://www.sciencedirect.com/science/article/pii/S0144861716309754

Skountzou I, Brock N, Lelutiu N and Compans RW (2017) Chapter 20 - Adjuvants for Skin Vaccination A2 - Schijns, Virgil E.J.C. In Immunopotentiators in Modern Vaccines (Second Edition). (Ed.^(Eds OHagan DT) pp. 399-419. (Academic Press). http://www.sciencedirect.com/science/article/pii/B9780128040195000207

Smułek W, Zdarta A, Pacholak A, Zgoła-Grześkowiak A, Marczak Ł, Jarzębski M and Kaczorek E (2017) Saponaria officinalis L. extract: Surface active properties and impact on environmental bacterial strains. Colloids and Surfaces B: Biointerfaces 150, 209-215. http://www.sciencedirect.com/science/article/pii/S0927776516308293

Tenon M, Feuillčre N, Roller M and Birtić S (2017) Rapid, cost-effective and accurate quantification of Yucca schidigera Roezl. steroidal saponins using HPLC-ELSD method. Food Chemistry 221, 1245-1252. http://www.sciencedirect.com/science/article/pii/S0308814616318568

Tippel J, Gies K, Harbaum-Piayda B, Steffen-Heins A and Drusch S (2017) Composition of Quillaja saponin extract affects lipid oxidation in oil-in-water emulsions. Food Chemistry 221, 386-394. http://www.sciencedirect.com/science/article/pii/S0308814616316727

Tiwari N, Gupta VK, Pandey P, Patel DK, Banerjee S, Darokar MP and Pal A (2017) Adjuvant effect of Asparagus racemosus Willd. derived saponins in antibody production, allergic response and pro-inflammatory cytokine modulation. Biomedicine & Pharmacotherapy 86, 555-561. http://www.sciencedirect.com/science/article/pii/S0753332216315451

Vardanega R, Santos DT and Meireles MAA (2017) Proposal for fractionating Brazilian ginseng extracts: Process intensification approach. Journal of Food Engineering 196, 73-80. http://www.sciencedirect.com/science/article/pii/S026087741630379X

Woods N, Niwasabutra K, Acevedo R, Igoli J, Altwaijry NA, Tusiimire J, Gray AI, Watson DG and Ferro VA (2017) Chapter 11 - Natural Vaccine Adjuvants and Immunopotentiators Derived From Plants, Fungi, Marine Organisms, and Insects A2 - Schijns, Virgil E.J.C. In Immunopotentiators in Modern Vaccines (Second Edition). (Ed.^(Eds OHagan DT) pp. 211-229. (Academic Press). http://www.sciencedirect.com/science/article/pii/B9780128040195000116

Wu HM, Lin LP, Xu QL, Han WB, Zhang S, Liu ZW, Mei YN, Yao ZJ and Tan RX (2017) Nodupetide, a potent insecticide and antimicrobial from Nodulisporium sp. associated with Riptortus pedestris. Tetrahedron Letters 58, 663-665. http://www.sciencedirect.com/science/article/pii/S0040403917300096

(2016) Melanthiaceae A2 - Aronson, J.K. In Meylers Side Effects of Drugs (Sixteenth Edition). (Ed.^(Eds  pp. 808-809. (Elsevier: Oxford). http://www.sciencedirect.com/science/article/pii/B9780444537171017285

(2016) Contents. Toxicology Reports 3, ii-x. http://www.sciencedirect.com/science/article/pii/S2214750016300944

(2016) Abstracts of ICI 2016 International Congress of Immunology, 21–26 August 2016, Melbourne, Australia. European Journal of Immunology 46, 1-1274. http://dx.doi.org/10.1002/eji.201670200

Additives EPanel o and Products or Substances used in Animal F (2016) Safety and efficacy of BIOSTRONG® 510 (essential oil of thyme and star anise) for chickens and minor avian species for fattening and rearing to point of lay. EFSA Journal 14, n/a-n/a. http://dx.doi.org/10.2903/j.efsa.2016.4351

Alihosseini F (2016) 10 - Plant-based compounds for antimicrobial textiles A2 - Sun, Gang. In Antimicrobial Textiles. (Ed.^(Eds  pp. 155-195. (Woodhead Publishing). http://www.sciencedirect.com/science/article/pii/B9780081005767000109

Appuhamy JADRN, France J and Kebreab E (2016) Models for predicting enteric methane emissions from dairy cows in North America, Europe, and Australia and New Zealand. Global Change Biology 22, 3039-3056. http://dx.doi.org/10.1111/gcb.13339

Bai L, Huan S, Gu J and McClements DJ (2016) Fabrication of oil-in-water nanoemulsions by dual-channel microfluidization using natural emulsifiers: Saponins, phospholipids, proteins, and polysaccharides. Food Hydrocolloids 61, 703-711. http://www.sciencedirect.com/science/article/pii/S0268005X16302855

Bai L and McClements DJ (2016) Formation and stabilization of nanoemulsions using biosurfactants: Rhamnolipids. Journal of Colloid and Interface Science 479, 71-79. http://www.sciencedirect.com/science/article/pii/S002197971630412X

Bartoš P, Dolan A, Smutný L, Šístková M, Celjak I, Šoch M and Havelka Z (2016) Effects of phytogenic feed additives on growth performance and on ammonia and greenhouse gases emissions in growing-finishing pigs. Animal Feed Science and Technology 212, 143-148. http://www.sciencedirect.com/science/article/pii/S0377840115300596

Bartoš P, Dolan A, Smutný L, Šístková M, Celjak I, Šoch M and Havelka Z (2016) Effects of phytogenic feed additives on growth performance and on ammonia and greenhouse gases emissions in growing-finishing pigs. Animal feed science and technology., 212. http://dx.doi.org/10.1016/j.anifeedsci.2015.11.003

Belanche A, Ramos-Morales E and Newbold CJ (2016) In vitro screening of natural feed additives from crustaceans, diatoms, seaweeds and plant extracts to manipulate rumen fermentation. Journal of the Science of Food and Agriculture 96, 3069-3078. http://dx.doi.org/10.1002/jsfa.7481

Bengtsson KL, Song H, Stertman L, Liu Y, Flyer DC, Massare MJ, Xu R-H, Zhou B, Lu H, Kwilas SA, Hahn TJ, Kpamegan E, Hooper J, Carrion Jr R, Glenn G and Smith G (2016) Matrix-M adjuvant enhances antibody, cellular and protective immune responses of a Zaire Ebola/Makona virus glycoprotein (GP) nanoparticle vaccine in mice. Vaccine 34, 1927-1935. http://www.sciencedirect.com/science/article/pii/S0264410X16001961

Bhargava S, Choubey S and Mishra S (2016) Vaccines against tuberculosis: A review. Indian Journal of Tuberculosis 63, 13-18. http://www.sciencedirect.com/science/article/pii/S0019570716300452

Borah B, Phukon P, Hazarika MP, Ahmed R, Sarmah DK, Wann SB, Das A and Bhau BS (2016) Calamus leptospadix Griff. a high saponin yielding plant with antimicrobial property. Industrial Crops and Products 82, 127-132. http://www.sciencedirect.com/science/article/pii/S0926669015305781

Böttcher S, Scampicchio M and Drusch S (2016) Mixtures of saponins and beta-lactoglobulin differ from classical protein/surfactant-systems at the air-water interface. Colloids and Surfaces A: Physicochemical and Engineering Aspects 506, 765-773. http://www.sciencedirect.com/science/article/pii/S0927775716305787

Chlibek R, Pauksens K, Rombo L, van Rijckevorsel G, Richardus JH, Plassmann G, Schwarz TF, Catteau G, Lal H and Heineman TC (2016) Long-term immunogenicity and safety of an investigational herpes zoster subunit vaccine in older adults. Vaccine 34, 863-868. http://www.sciencedirect.com/science/article/pii/S0264410X15013493

Cibulski SP, Mourglia-Ettlin G, Teixeira TF, Quirici L, Roehe PM, Ferreira F and Silveira F (2016) Novel ISCOMs from Quillaja brasiliensis saponins induce mucosal and systemic antibody production, T-cell responses and improved antigen uptake. Vaccine 34, 1162-1171. http://www.sciencedirect.com/science/article/pii/S0264410X16000736

Cibulski SP, Mourglia-Ettlin G, Teixeira TF, Quirici L, Roehe PM, Ferreira F and Silveira F (2016) Novel ISCOMs from Quillaja brasiliensis saponins induce mucosal and systemic antibody production, T-cell responses and improved antigen uptake. Vaccine. 24, 34. http://dx.doi.org/10.1016/j.vaccine.2016.01.029

Cibulski SP, Silveira F, Mourglia-Ettlin G, Teixeira TF, dos Santos HF, Yendo AC, de Costa F, Fett-Neto AG, Gosmann G and Roehe PM (2016) Quillaja brasiliensis saponins induce robust humoral and cellular responses in a bovine viral diarrhea virus vaccine in mice. Comparative Immunology, Microbiology and Infectious Diseases 45, 1-8. http://www.sciencedirect.com/science/article/pii/S0147957116300030

Collier MA, Peine KJ, Gautam S, Oghumu S, Varikuti S, Borteh H, Papenfuss TL, Sataoskar AR, Bachelder EM and Ainslie KM (2016) Host-mediated Leishmania donovani treatment using AR-12 encapsulated in acetalated dextran microparticles. International Journal of Pharmaceutics 499, 186-194. http://www.sciencedirect.com/science/article/pii/S0378517316300084

Cruz MdFSJ, Pereira GM, Ribeiro MG, da Silva AM, Tinoco LW, da Silva BP and Parente JP (2016) Ingasaponin, a complex triterpenoid saponin with immunological adjuvant activity from Inga laurina. Carbohydrate Research 420, 23-31. http://www.sciencedirect.com/science/article/pii/S0008621515003687

Cunningham AL, Garçon N, Leo O, Friedland LR, Strugnell R, Laupčze B, Doherty M and Stern P (2016) Vaccine development: From concept to early clinical testing. Vaccine 34, 6655-6664. http://www.sciencedirect.com/science/article/pii/S0264410X16309173

Dalle Zotte A, Celia C and Szendrő Z (2016) Herbs and spices inclusion as feedstuff or additive in growing rabbit diets and as additive in rabbit meat: A review. Livestock Science 189, 82-90. http://www.sciencedirect.com/science/article/pii/S1871141316300877

de la Barrera F, Rubio P and Banzhaf E (2016) The value of vegetation cover for ecosystem services in the suburban context. Urban Forestry & Urban Greening 16, 110-122. http://www.sciencedirect.com/science/article/pii/S1618866716000169

Díaz-Forestier J, Gómez M, Celis-Diez JL and Montenegro G (2016) Nectary structure in four melliferous plant species native to Chile. Flora - Morphology, Distribution, Functional Ecology of Plants 221, 100-106. http://www.sciencedirect.com/science/article/pii/S0367253016300238

Díaz-Forestier J, Gómez M, Celis-Diez JL and Montenegro G (2016) Nectary structure in four melliferous plant species native to Chile. Flora., 221. http://dx.doi.org/10.1016/j.flora.2016.02.013

Dos Reis JS, Zangerônimo MG, Ogoshi RCS, França J, Costa AC, Almeida TN, Dos Santos JPF, Pires CP, Chizzotti AF, Leite CAL and Saad FMOB (2016) Inclusion of Yucca schidigera extract in diets with different protein levels for dogs. Animal Science Journal 87, 1019-1027. http://dx.doi.org/10.1111/asj.12535

Duarte MC, Lage DP, Martins VT, Costa LE, Lage LMR, Carvalho AMRS, Ludolf F, Santos TTO, Roatt BM, Menezes-Souza D, Fernandes AP, Tavares CAP and Coelho EAF (2016) A vaccine combining two Leishmania braziliensis proteins offers heterologous protection against Leishmania infantum infection. Molecular Immunology 76, 70-79. http://www.sciencedirect.com/science/article/pii/S016158901630116X

Ebensperger LA, Correa LA, León C, Ramírez-Estrada J, Abades S, Villegas Á and Hayes LD (2016) The modulating role of group stability on fitness effects of group size is different in females and males of a communally rearing rodent. Journal of Animal Ecology 85, 1502-1515. http://dx.doi.org/10.1111/1365-2656.12566

Fangueiro JF, Souto EB and Silva AM (2016) 9 - Encapsulation of nutraceuticals in novel delivery systems A2 - Grumezescu, Alexandru Mihai. In Nutraceuticals. (Ed.^(Eds  pp. 305-342. (Academic Press). http://www.sciencedirect.com/science/article/pii/B9780128043059000099

Farook MA, Vimal S, Madan N, Taju G, Abdul Majeed S, Nambi KSN, Balasubramanian G and Sahul Hameed AS (2016) Immunomodulatory effect of Cynodon dactylon against white tail disease of giant freshwater prawn, Macrobrachium rosenbergii (de Man, 1879). Aquaculture Research 47, 3421-3431. http://dx.doi.org/10.1111/are.12789

Gandhi GR, Barreto PG, Lima BdS, Quintans JdSS, Araújo AAdS, Narain N, Quintans-Júnior LJ and Gurgel RQ (2016) Medicinal plants and natural molecules with in vitro and in vivo activity against rotavirus: A systematic review. Phytomedicine 23, 1830-1842. http://www.sciencedirect.com/science/article/pii/S0944711316302082

Garçon N, Silvano J, Kuper CF, Baudson N, Gérard C, Forster R and Segal L (2016) Non-clinical safety evaluation of repeated intramuscular administration of the AS15 immunostimulant combined with various antigens in rabbits and cynomolgus monkeys. Journal of Applied Toxicology 36, 238-256. http://dx.doi.org/10.1002/jat.3167

Gillard P, Yang P-C, Danilovits M, Su W-J, Cheng S-L, Pehme L, Bollaerts A, Jongert E, Moris P, Ofori-Anyinam O, Demoitié M-A and Castro M (2016) Safety and immunogenicity of the M72/AS01E candidate tuberculosis vaccine in adults with tuberculosis: A phase II randomised study. Tuberculosis 100, 118-127. http://www.sciencedirect.com/science/article/pii/S1472979216301305

Guerreiro AC, Gago CML, Faleiro ML, Miguel MGC and Antunes MDC (2016) Edible coatings enriched with essential oils for extending the shelf-life of ‘Bravo de Esmolfe’ fresh-cut apples. International Journal of Food Science & Technology 51, 87-95. http://dx.doi.org/10.1111/ijfs.12949

Gupta A, Das S, Schanen B and Seal S (2016) Adjuvants in micro- to nanoscale: current state and future direction. Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 8, 61-84. http://dx.doi.org/10.1002/wnan.1354

Güroy B, Mantoğlu S, Merrifield DL and Guroy D (2016) Effects of dietary Nutrafito Plus on growth, haemotological parameters and total ammonia-nitrogen excretion of juvenile striped catfish Pangasianodon hypophthalmus. Aquaculture Research 47, 1770-1777. http://dx.doi.org/10.1111/are.12634

Hernández Á, Arellano EC, Morales-Moraga D and Miranda MD (2016) Understanding the effect of three decades of land use change on soil quality and biomass productivity in a Mediterranean landscape in Chile. CATENA 140, 195-204. http://www.sciencedirect.com/science/article/pii/S0341816216300443

Hernández A, Miranda MD, Arellano EC and Dobbs C (2016) Landscape trajectories and their effect on fragmentation for a Mediterranean semi-arid ecosystem in Central Chile. Journal of Arid Environments 127, 74-81. http://www.sciencedirect.com/science/article/pii/S0140196315300689

Hu B, Wang J, Guo Y, Chen T, Ni W, Yuan H, Zhang N, Xie F and Tai G (2016) Pre-clinical toxicity and immunogenicity evaluation of a MUC1–MBP/BCG anti-tumor vaccine. International Immunopharmacology 33, 108-118. http://www.sciencedirect.com/science/article/pii/S1567576916300418

Huntley NF, Naumann HD, Kenny AL and Kerley MS (2016) Black rhinoceros (Diceros bicornis) and domestic horse (Equus caballus) hindgut microflora demonstrate similar fermentation responses to grape seed extract supplementation in vitro. Journal of Animal Physiology and Animal Nutrition, n/a-n/a. http://dx.doi.org/10.1111/jpn.12587

J. Alaniz A, Galleguillos M and Perez-Quezada JF (2016) Assessment of quality of input data used to classify ecosystems according to the IUCN Red List methodology: The case of the central Chile hotspot. Biological Conservation 204, Part B, 378-385. http://www.sciencedirect.com/science/article/pii/S0006320716306954

Junqueira-Gonçalves MP, Salinas GE, Bruna JE and Niranjan K (2016) An assessment of lactobiopolymer-montmorillonite composites for dip coating applications on fresh strawberries. Journal of the Science of Food and Agriculture, n/a-n/a. http://dx.doi.org/10.1002/jsfa.7985

Kaczorek E, Smułek W, Zdarta A, Sawczuk A and Zgoła-Grześkowiak A (2016) Influence of saponins on the biodegradation of halogenated phenols. Ecotoxicology and Environmental Safety 131, 127-134. http://www.sciencedirect.com/science/article/pii/S0147651316301774

Karthik S, Raghavan CV, Marslin G, Rahman H, Selvaraj D, Balakumar K and Franklin G (2016) Quillaja saponin: A prospective emulsifier for the preparation of solid lipid nanoparticles. Colloids and Surfaces B: Biointerfaces 147, 274-280. http://www.sciencedirect.com/science/article/pii/S0927776516305677

Kaur K (2016) 18 - Nanoemulsions as delivery vehicles for food and pharmaceuticals A2 - Grumezescu, Alexandru Mihai. In Emulsions. (Ed.^(Eds  pp. 611-649. (Academic Press). http://www.sciencedirect.com/science/article/pii/B9780128043066000180

Lage DP, Martins VT, Duarte MC, Costa LE, Tavares GdSV, Ramos FF, Chávez-Fumagalli MA, Menezes-Souza D, Roatt BM, Tavares CAP and Coelho EAF (2016) Cross-protective efficacy of Leishmania infantum LiHyD protein against tegumentary leishmaniasis caused by Leishmania major and Leishmania braziliensis species. Acta Tropica 158, 220-230. http://www.sciencedirect.com/science/article/pii/S0001706X16301012

Leroux-Roels G, Marchant A, Levy J, Van Damme P, Schwarz TF, Horsmans Y, Jilg W, Kremsner PG, Haelterman E, Clément F, Gabor JJ, Esen M, Hens A, Carletti I, Fissette L, Tavares Da Silva F, Burny W, Janssens M, Moris P, Didierlaurent AM, Van Der Most R, Garçon N, Van Belle P and Van Mechelen M (2016) Impact of adjuvants on CD4+ T cell and B cell responses to a protein antigen vaccine: Results from a phase II, randomized, multicenter trial. Clinical Immunology 169, 16-27. http://www.sciencedirect.com/science/article/pii/S1521661616300808

Levenhagen MA, Conte H and Costa-Cruz JM (2016) Current progress toward vaccine and passive immunization approaches for Strongyloides spp. Immunology Letters 180, 17-23. http://www.sciencedirect.com/science/article/pii/S0165247816302152

Linke C and Drusch S (2016) Turbidity in oil-in-water-emulsions — Key factors and visual perception. Food Research International 89, Part 1, 202-210. http://www.sciencedirect.com/science/article/pii/S0963996916302952

Liu X, Da Z, Wang Y, Niu H, Li R, Yu H, He S, Guo M, Wang Y, Luo Y, Ma X and Zhu B (2016) A novel liposome adjuvant DPC mediates Mycobacterium tuberculosis subunit vaccine well to induce cell-mediated immunity and high protective efficacy in mice. Vaccine 34, 1370-1378. http://www.sciencedirect.com/science/article/pii/S0264410X16001018

Liu Y and Chen C (2016) Role of nanotechnology in HIV/AIDS vaccine development. Advanced Drug Delivery Reviews 103, 76-89. http://www.sciencedirect.com/science/article/pii/S0169409X16300758

Lopatin J, Dolos K, Hernández HJ, Galleguillos M and Fassnacht FE (2016) Comparing Generalized Linear Models and random forest to model vascular plant species richness using LiDAR data in a natural forest in central Chile. Remote Sensing of Environment 173, 200-210. http://www.sciencedirect.com/science/article/pii/S0034425715302169

Lusk LT (2016) Chapter 10 - Controlling Beer Foam and Gushing A2 - Bamforth, Charles W. In Brewing Materials and Processes. (Ed.^(Eds  pp. 175-198. (Academic Press: San Diego). http://www.sciencedirect.com/science/article/pii/B9780127999548000101

Marciani DJ (2016) A retrospective analysis of the Alzheimers disease vaccine progress – The critical need for new development strategies. Journal of Neurochemistry 137, 687-700. http://dx.doi.org/10.1111/jnc.13608

Martel-Cea A, Maldonado A, Grosjean M, Alvial I, de Jong R, Fritz SC and von Gunten L (2016) Late Holocene environmental changes as recorded in the sediments of high Andean Laguna Chepical, Central Chile (32°S; 3050 m a.s.l.). Palaeogeography, Palaeoclimatology, Palaeoecology 461, 44-54. http://www.sciencedirect.com/science/article/pii/S0031018216303005

Martins VT, Lage DP, Duarte MC, Costa LE, Chávez-Fumagalli MA, Roatt BM, Menezes-Souza D, Tavares CAP and Coelho EAF (2016) Cross-protective efficacy from a immunogen firstly identified in Leishmania infantum against tegumentary leishmaniasis. Parasite Immunology 38, 108-117. http://dx.doi.org/10.1111/pim.12304

Martins VT, Lage DP, Duarte MC, Costa LE, Garde E, Rodrigues MR, Chávez-Fumagalli MA, Menezes-Souza D, Roatt BM, Tavares CAP, Soto M and Coelho EAF (2016) A new Leishmania-specific hypothetical protein, LiHyT, used as a vaccine antigen against visceral leishmaniasis. Acta Tropica 154, 73-81. http://www.sciencedirect.com/science/article/pii/S0001706X15301546

McClements DJ and Gumus CE (2016) Natural emulsifiers — Biosurfactants, phospholipids, biopolymers, and colloidal particles: Molecular and physicochemical basis of functional performance. Advances in Colloid and Interface Science 234, 3-26. http://www.sciencedirect.com/science/article/pii/S0001868616300380

Mohr E and Siegrist C-A (2016) Vaccination in early life: standing up to the challenges. Current Opinion in Immunology 41, 1-8. http://www.sciencedirect.com/science/article/pii/S0952791516300292

Ngambi JW, Li R, Mu C, Song W, Liu L and Wang C (2016) Dietary administration of saponin stimulates growth of the swimming crab Portunus trituberculatus and enhances its resistance against Vibrio alginolyticus infection. Fish & Shellfish Immunology 59, 305-311. http://www.sciencedirect.com/science/article/pii/S1050464816306842

Ortega YH, Mosquera DMG, Galapththi S, Santos BT, González GS, Foubert K, Pieters L, Calderon PB and Apers S (2016) Safety assessment of a traditionally used extract from leaves of Boldoa purpurascens. Journal of Ethnopharmacology 192, 302-308. http://www.sciencedirect.com/science/article/pii/S0378874116304329

Ovalle JF, Arellano EC, Ginocchio R and Becerra P (2016) Fertilizer location modifies root zone salinity, root morphology, and water-stress resistance of tree seedlings according to the watering regime in a dryland reforestation. Journal of Plant Nutrition and Soil Science 179, 223-233. http://dx.doi.org/10.1002/jpln.201500181

Ovalle JF, Arellano EC, Ginocchio R and Becerra P (2016) Fertilizer location modifies root zone salinity, root morphology, and water?stress resistance of tree seedlings according to the watering regime in a dryland reforestation. Zeitschrift fu?r Pflanzenerna?hrung und Bodenkunde. 179, 223-233. http://dx.doi.org/10.1002/jpln.201500181

Ozturk B and McClements DJ (2016) Progress in natural emulsifiers for utilization in food emulsions. Current Opinion in Food Science 7, 1-6. http://www.sciencedirect.com/science/article/pii/S2214799315001009

Pagureva N, Tcholakova S, Golemanov K, Denkov N, Pelan E and Stoyanov SD (2016) Surface properties of adsorption layers formed from triterpenoid and steroid saponins. Colloids and Surfaces A: Physicochemical and Engineering Aspects 491, 18-28. http://www.sciencedirect.com/science/article/pii/S0927775715303964

Read J, Sanson G and Pérez Trautmann MF (2016) Leaf traits in Chilean matorral: sclerophylly within, among, and beyond matorral, and its environmental determinants. Ecology and Evolution 6, 1430-1446. http://dx.doi.org/10.1002/ece3.1970

Reguera RM, Morán M, Pérez-Pertejo Y, García-Estrada C and Balańa-Fouce R (2016) Current status on prevention and treatment of canine leishmaniasis. Veterinary Parasitology 227, 98-114. http://www.sciencedirect.com/science/article/pii/S0304401716302709

Reichert CL, Salminen H, Leuenberger BH and Weiss J (2016) Influence of heat on miscibility of Quillaja saponins in mixtures with a co-surfactant. Food Research International 88, Part A, 16-23. http://www.sciencedirect.com/science/article/pii/S0963996916301223

Rojo J, Sousa-Herves A and Mascaraque A (2016) Perspectives of Carbohydrates in Drug Discovery. In Reference Module in Chemistry, Molecular Sciences and Chemical Engineering. (Ed.^(Eds  pp. (Elsevier). http://www.sciencedirect.com/science/article/pii/B978012409547212311X

Root-Bernstein M (2016) Personal reflections on natural history as common ground for interdisciplinary multispecies socio-ecological research. Geo: Geography and Environment 3, n/a-n/a. http://dx.doi.org/10.1002/geo2.15

Rosa MTMG, Silva EK, Santos DT, Petenate AJ and Meireles MAA (2016) Obtaining annatto seed oil miniemulsions by ultrasonication using aqueous extract from Brazilian ginseng roots as a biosurfactant. Journal of Food Engineering 168, 68-78. http://www.sciencedirect.com/science/article/pii/S0260877415003337

Sabur A, Asad M and Ali N (2016) Lipid based delivery and immuno-stimulatory systems: Master tools to combat leishmaniasis. Cellular Immunology 309, 55-60. http://www.sciencedirect.com/science/article/pii/S0008874916300600

Salminen H, Gömmel C, Leuenberger BH and Weiss J (2016) Influence of encapsulated functional lipids on crystal structure and chemical stability in solid lipid nanoparticles: Towards bioactive-based design of delivery systems. Food Chemistry 190, 928-937. http://www.sciencedirect.com/science/article/pii/S0308814615009462

Sarkhel S (2016) Evaluation of the anti-inflammatory activities of Quillaja saponaria Mol. saponin extract in mice. Toxicology Reports 3, 1-3. http://www.sciencedirect.com/science/article/pii/S2214750015300846

Smith AJ, Li Y, Bazin HG, St-Jean JR, Larocque D, Evans JT and Baldridge JR (2016) Evaluation of novel synthetic TLR7/8 agonists as vaccine adjuvants. Vaccine 34, 4304-4312. http://www.sciencedirect.com/science/article/pii/S0264410X16305606

Smułek W, Zdarta A, Łuczak M, Krawczyk P, Jesionowski T and Kaczorek E (2016) Sapindus saponins’ impact on hydrocarbon biodegradation by bacteria strains after short- and long-term contact with pollutant. Colloids and Surfaces B: Biointerfaces 142, 207-213. http://www.sciencedirect.com/science/article/pii/S0927776516301308

Tippel J, Lehmann M, von Klitzing R and Drusch S (2016) Interfacial properties of Quillaja saponins and its use for micellisation of lutein esters. Food Chemistry 212, 35-42. http://www.sciencedirect.com/science/article/pii/S0308814616308184

Tippel J, Lehmann M, von Klitzing R and Drusch S (2016) Interfacial properties of Quillaja saponins and its use for micellisation of lutein esters. Food chemistry. 01, 212. http://dx.doi.org/10.1016/j.foodchem.2016.05.130

Tippel J, Reim V, Rohn S and Drusch S (2016) Colour stability of lutein esters in liquid and spray dried delivery systems based on Quillaja saponins. Food Research International 87, 68-75. http://www.sciencedirect.com/science/article/pii/S0963996916302496

Úbeda X and Sarricolea P (2016) Wildfires in Chile: A review. Global and Planetary Change 146, 152-161. http://www.sciencedirect.com/science/article/pii/S0921818116302090

Vekemans J (2016) Chapter 19 - Major Global Vaccine Challenges: Recent Progress in Malaria Vaccine Development A2 - Bloom, Barry R. In The Vaccine Book (Second Edition). (Ed.^(Eds Lambert P-H) pp. 385-399. (Academic Press). http://www.sciencedirect.com/science/article/pii/B9780128021743000199

Wojciechowski K, Orczyk M, Gutberlet T and Geue T (2016) Complexation of phospholipids and cholesterol by triterpenic saponins in bulk and in monolayers. Biochimica et Biophysica Acta (BBA) - Biomembranes 1858, 363-373. http://www.sciencedirect.com/science/article/pii/S0005273615003983

Wojciechowski K, Orczyk M, Trapp M and Gutberlet T (2016) Effect of triterpene and steroid saponins on lecithin bilayers. Colloids and Surfaces A: Physicochemical and Engineering Aspects 510, 150-158. http://www.sciencedirect.com/science/article/pii/S0927775716303107

Zhang J, Wang Z and Liu X (2016) Characterization of Acylated Anthocyanins in Red Cabbage via Comprehensive Two-Dimensional High Performance Liquid Chromatography and HPLC-MS. Journal of Food Processing and Preservation, n/a-n/a. http://dx.doi.org/10.1111/jfpp.13129

(2015) Chile: Naturex – natural plant extracts for colour emulsions. Focus on Pigments 2015, 5-6. http://www.sciencedirect.com/science/article/pii/S0969621015001447

Aguilera N, Guedes LM, Becerra J, Baeza C and Hernández V (2015) Morphological effects at radicle level by direct contact of invasive Acacia dealbata Link. Flora - Morphology, Distribution, Functional Ecology of Plants 215, 54-59. http://www.sciencedirect.com/science/article/pii/S0367253015000754

Aguilera N, Guedes LM, Becerra J, Baeza C and Hernández V (2015) Morphological effects at radicle level by direct contact of invasive Acacia dealbata Link. Flora., 215. http://dx.doi.org/10.1016/j.flora.2015.07.007

Aguilera N, Sanhueza C, Guedes LM, Becerra J, Carrasco S and Hernández V (2015) Does Acacia dealbata express shade tolerance in Mediterranean forest ecosystems of South America? Ecology and Evolution 5, 3338-3351. http://dx.doi.org/10.1002/ece3.1606

Anantasook N, Wanapat M, Cherdthong A and Gunun P (2015) Effect of tannins and saponins in Samanea saman on rumen environment, milk yield and milk composition in lactating dairy cows. Journal of Animal Physiology and Animal Nutrition 99, 335-344. http://dx.doi.org/10.1111/jpn.12198

Awad E, Awaad AS and Esteban MA (2015) Effects of dihydroquercetin obtained from deodar (Cedrus deodara) on immune status of gilthead seabream (Sparus aurata L.). Fish & Shellfish Immunology 43, 43-50. http://www.sciencedirect.com/science/article/pii/S105046481400480X

Beck Z, Matyas GR and Alving CR (2015) Detection of liposomal cholesterol and monophosphoryl lipid A by QS-21 saponin and Limulus polyphemus amebocyte lysate. Biochimica et Biophysica Acta (BBA) - Biomembranes 1848, 775-780. http://www.sciencedirect.com/science/article/pii/S0005273614004337

Beck Z, Matyas GR, Jalah R, Rao M, Polonis VR and Alving CR (2015) Differential immune responses to HIV-1 envelope protein induced by liposomal adjuvant formulations containing monophosphoryl lipid A with or without QS21. Vaccine 33, 5578-5587. http://www.sciencedirect.com/science/article/pii/S0264410X1501244X

Berlowska J, Dudkiewicz M, Kregiel D, Czyzowska A and Witonska I (2015) Cell lysis induced by membrane-damaging detergent saponins from Quillaja saponaria. Enzyme and Microbial Technology 75–76, 44-48. http://www.sciencedirect.com/science/article/pii/S0141022915000666

Bhatia S and Dahiya R (2015) Chapter 8 - Plant-Based Biotechnological Products With Their Production Host, Modes of Delivery Systems, and Stability Testing. In Modern Applications of Plant Biotechnology in Pharmaceutical Sciences. (Ed.^(Eds  pp. 293-331. (Academic Press: Boston). http://www.sciencedirect.com/science/article/pii/B978012802221400008X

Bobbala S, McDowell A and Hook S (2015) Quantitation of the immunological adjuvants, monophosphoryl lipid A and Quil A in poly (lactic-co-glycolic acid) nanoparticles using high performance liquid chromatography with evaporative light scattering detection. Journal of Chromatography B 975, 45-51. http://www.sciencedirect.com/science/article/pii/S1570023214006953

Boyd CE and McNevin AA (2015) Chemicals in Aquaculture. In Aquaculture, Resource Use, and the Environment. (Ed.^(Eds  pp. 173-210. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118857915.ch9

Bridi R, Montenegro G, Nuńez-Quijada G, Giordano A, Fernanda Morán-Romero M, Jara-Pezoa I, Speisky H, Atala E and López-Alarcón C (2015) International Regulations of Propolis Quality: Required Assays do not Necessarily Reflect their Polyphenolic-Related In Vitro Activities. Journal of Food Science 80, C1188-C1195. http://dx.doi.org/10.1111/1750-3841.12881

Britto-Costa PH and Ruotolo LAM (2015) Parametric study of copper electrowinning using a pulsed-bed electrode reactor. Journal of Chemical Technology & Biotechnology 90, 1646-1656. http://dx.doi.org/10.1002/jctb.4472

Castańeda LE, Godoy K, Manzano M, Marquet PA and Barbosa O (2015) Comparison of soil microbial communities inhabiting vineyards and native sclerophyllous forests in central Chile. Ecology and Evolution 5, 3857-3868. http://dx.doi.org/10.1002/ece3.1652

Cordeiro AS, Alonso MJ and de la Fuente M (2015) Nanoengineering of vaccines using natural polysaccharides. Biotechnology Advances 33, 1279-1293. http://www.sciencedirect.com/science/article/pii/S0734975015300094

Couto A, Kortner TM, Penn M, Řstby G, Bakke AM, Krogdahl Ĺ and Oliva-Teles A (2015) Saponins and phytosterols in diets for European sea bass (Dicentrarchus labrax) juveniles: effects on growth, intestinal morphology and physiology. Aquaculture Nutrition 21, 180-193. http://dx.doi.org/10.1111/anu.12146

da Costa C, Walker B and Bonavia A (2015) Tuberculosis Vaccines – state of the art, and novel approaches to vaccine development. International Journal of Infectious Diseases 32, 5-12. http://www.sciencedirect.com/science/article/pii/S1201971214017159

de Jesus Pereira NC, Régis WCB, Costa LE, de Oliveira JS, da Silva AG, Martins VT, Duarte MC, de Souza JRR, Lage PS, Schneider MS, Melo MN, Soto M, Soares SA, Tavares CAP, Chávez-Fumagalli MA and Coelho EAF (2015) Evaluation of adjuvant activity of fractions derived from Agaricus blazei, when in association with the recombinant LiHyp1 protein, to protect against visceral leishmaniasis. Experimental Parasitology 153, 180-190. http://www.sciencedirect.com/science/article/pii/S0014489415000892

Destexhe E, Grosdidier E, Baudson N, Forster R, Gerard C, Garçon N and Segal L (2015) Non-clinical safety evaluation of single and repeated intramuscular administrations of MAGE-A3 Cancer Immunotherapeutic in rabbits and cynomolgus monkeys. Journal of Applied Toxicology 35, 717-728. http://dx.doi.org/10.1002/jat.3025

Destexhe E, Stannard D, Wilby OK, Grosdidier E, Baudson N, Forster R, Gérard CM, Garçon N and Segal L (2015) Nonclinical reproductive and developmental safety evaluation of the MAGE-A3 Cancer Immunotherapeutic, a therapeutic vaccine for cancer treatment. Reproductive Toxicology 51, 90-105. http://www.sciencedirect.com/science/article/pii/S0890623814003207

Gilabert-Oriol R, Weng A, von Mallinckrodt B, Stöshel A, Nissi L, Melzig MF, Fuchs H and Thakur M (2015) Electrophoretic mobility as a tool to separate immune adjuvant saponins from Quillaja saponaria Molina. International Journal of Pharmaceutics 487, 39-48. http://www.sciencedirect.com/science/article/pii/S0378517315002793

Greatrex BW, Daines AM, Hook S, Lenz DH, McBurney W, Rades T and Rendle PM (2015) Synthesis, Formulation, and Adjuvanticity of Monodesmosidic Saponins with Olenanolic Acid, Hederagenin and Gypsogenin Aglycones, and some C-28 Ester Derivatives. ChemistryOpen 4, 740-755. http://dx.doi.org/10.1002/open.201500149

Griffiths KE, Balding ST, Dickie JB, Lewis GP, Pearce TR and Grenyer R (2015) Maximizing the phylogenetic diversity of seed banks. Conservation Biology 29, 370-381. http://dx.doi.org/10.1111/cobi.12390

Harvey DJ (2015) Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: An update for 2009–2010. Mass Spectrometry Reviews 34, 268-422. http://dx.doi.org/10.1002/mas.21411

Hernández A, Miranda M, Arellano EC, Saura S and Ovalle C (2015) Landscape dynamics and their effect on the functional connectivity of a Mediterranean landscape in Chile. Ecological Indicators 48, 198-206. http://www.sciencedirect.com/science/article/pii/S1470160X14003653

Hoffman SL, Vekemans J, Richie TL and Duffy PE (2015) The March Toward Malaria Vaccines. American Journal of Preventive Medicine 49, S319-S333. http://www.sciencedirect.com/science/article/pii/S0749379715005504

Hoffman SL, Vekemans J, Richie TL and Duffy PE (2015) The march toward malaria vaccines. Vaccine 33, Supplement 4, D13-D23. http://www.sciencedirect.com/science/article/pii/S0264410X15010701

Jabbar S, Abid M, Wu T, Hashim MM, Saeeduddin M, Hu B, Lei S and Zeng X (2015) Ultrasound-Assisted Extraction of Bioactive Compounds and Antioxidants from Carrot Pomace: A Response Surface Approach. Journal of Food Processing and Preservation 39, 1878-1888. http://dx.doi.org/10.1111/jfpp.12425

Jain NK, Sahni N, Kumru OS, Joshi SB, Volkin DB and Russell Middaugh C (2015) Formulation and stabilization of recombinant protein based virus-like particle vaccines. Advanced Drug Delivery Reviews 93, 42-55. http://www.sciencedirect.com/science/article/pii/S0169409X14002312

Kijanka G, Sauerborn M, Boon L, Schellekens H and Brinks V (2015) Development of ADA Against Recombinant Human Interferon Beta in Immune Tolerant Mice Requires Rapid Recruitment of CD4+ T Cells, Induces Formation of Germinal Centers but Lacks Susceptibility for (Most) Adjuvants. Journal of Pharmaceutical Sciences 104, 396-406. http://www.sciencedirect.com/science/article/pii/S0022354915302021

Kojarunchitt T, Baldursdottir S, Dong Y-D, Boyd BJ, Rades T and Hook S (2015) Modified thermoresponsive Poloxamer 407 and chitosan sol–gels as potential sustained-release vaccine delivery systems. European Journal of Pharmaceutics and Biopharmaceutics 89, 74-81. http://www.sciencedirect.com/science/article/pii/S0939641114003531

Kulikowska D, Gusiatin ZM, Bułkowska K and Kierklo K (2015) Humic substances from sewage sludge compost as washing agent effectively remove Cu and Cd from soil. Chemosphere 136, 42-49. http://www.sciencedirect.com/science/article/pii/S0045653515003276

Kumar A, Singh A and Ekavali (2015) A review on Alzheimers disease pathophysiology and its management: an update. Pharmacological Reports 67, 195-203. http://www.sciencedirect.com/science/article/pii/S1734114014002886

Lage DP, Martins VT, Duarte MC, Garde E, Chávez-Fumagalli MA, Menezes-Souza D, Roatt BM, Tavares CAP, Soto M and Coelho EAF (2015) Prophylactic properties of a Leishmania-specific hypothetical protein in a murine model of visceral leishmaniasis. Parasite Immunology 37, 646-656. http://dx.doi.org/10.1111/pim.12287

Leroux-Roels G, Van Belle P, Vandepapeliere P, Horsmans Y, Janssens M, Carletti I, Garçon N, Wettendorff M and Van Mechelen M (2015) Vaccine Adjuvant Systems containing monophosphoryl lipid A and QS-21 induce strong humoral and cellular immune responses against hepatitis B surface antigen which persist for at least 4 years after vaccination. Vaccine 33, 1084-1091. http://www.sciencedirect.com/science/article/pii/S0264410X14014698

Leroux-Roels I, Devaster J-M, Leroux-Roels G, Verlant V, Henckaerts I, Moris P, Hermand P, Van Belle P, Poolman JT, Vandepapeličre P and Horsmans Y (2015) Adjuvant system AS02V enhances humoral and cellular immune responses to pneumococcal protein PhtD vaccine in healthy young and older adults: Randomised, controlled trials. Vaccine 33, 577-584. http://www.sciencedirect.com/science/article/pii/S0264410X13014308

Letelier L, Harvey N, Valderrama A, Stoll A and González-Rodríguez A (2015) Isolation and Characterization of 12 Microsatellite Loci in Soapbark, Quillaja saponaria (Quillajaceae). Applications in plant sciences. 3. http://dx.doi.org/10.3732%2Fapps.1500024

Maier C, Conrad J, Carle R, Weiss J and Schweiggert RM (2015) Phenolic Constituents in Commercial Aqueous Quillaja (Quillaja saponaria Molina) Wood Extracts. Journal of agricultural and food chemistry. 63, 1756-1762. http://dx.doi.org/10.1021/jf506277p

Maier C, Conrad J, Steingass CB, Beifuss U, Carle R and Schweiggert RM (2015) Quillajasides A and B: New Phenylpropanoid Sucrose Esters from the Inner Bark of Quillaja saponaria Molina. Journal of agricultural and food chemistry. 63, 8905-8911. http://dx.doi.org/10.1021/acs.jafc.5b03532

Maier C, Oechsle AM and Weiss J (2015) Cross-linking oppositely charged oil-in-water emulsions to enhance heteroaggregate stability. Colloids and Surfaces B: Biointerfaces 135, 525-532. http://www.sciencedirect.com/science/article/pii/S0927776515301260

Marciani DJ (2015) Is fucose the answer to the immunomodulatory paradox of Quillaja saponins? International Immunopharmacology 29, 908-913. http://www.sciencedirect.com/science/article/pii/S1567576915301612

McEntee C, Lavelle EC and O’Hagan DT (2015) Chapter 63 - Antigen Delivery Systems I: Nonliving Microparticles, Liposomes, and Immune-Stimulating Complexes (ISCOMs) A2 - Mestecky, Jiri. In Mucosal Immunology (Fourth Edition). (Ed.^(Eds Strober W, Russell MW, Kelsall BL, Cheroutre H and Lambrecht BN) pp. 1211-1231. (Academic Press: Boston). http://www.sciencedirect.com/science/article/pii/B978012415847400063X

Montenegro D, Kalpana K, Chrissian C, Sharma A, Takaoka A, Iacovidou M, Soll CE, Aminova O, Heguy A, Cohen L, Shen S and Kawamura A (2015) Uncovering potential ‘herbal probiotics’ in Juzen-taiho-to through the study of associated bacterial populations. Bioorganic & Medicinal Chemistry Letters 25, 466-469. http://www.sciencedirect.com/science/article/pii/S0960894X14013444

Moreno A and Joyner C (2015) Malaria vaccine clinical trials: whats on the horizon. Current Opinion in Immunology 35, 98-106. http://www.sciencedirect.com/science/article/pii/S0952791515000898

Muntaha S-T and Khan MN (2015) Natural surfactant extracted from Sapindus mukurossi as an eco-friendly alternate to synthetic surfactant – a dye surfactant interaction study. Journal of Cleaner Production 93, 145-150. http://www.sciencedirect.com/science/article/pii/S095965261500027X

O’Hagan DT and Fox CB (2015) New generation adjuvants – From empiricism to rational design. Vaccine 33, Supplement 2, B14-B20. http://www.sciencedirect.com/science/article/pii/S0264410X15001565

Orczyk M and Wojciechowski K (2015) Comparison of the effect of two Quillaja bark saponin extracts on DPPC and DPPC/cholesterol Langmuir monolayers. Colloids and Surfaces B: Biointerfaces 136, 291-299. http://www.sciencedirect.com/science/article/pii/S0927776515301879

Patil HP, Murugappan S, de Vries-Idema J, Meijerhof T, de Haan A, Frijlink HW, Wilschut J, Hinrichs WLJ and Huckriede A (2015) Comparison of adjuvants for a spray freeze-dried whole inactivated virus influenza vaccine for pulmonary administration. European Journal of Pharmaceutics and Biopharmaceutics 93, 231-241. http://www.sciencedirect.com/science/article/pii/S0939641115001708

Patra AK and Yu Z (2015) Effects of garlic oil, nitrate, saponin and their combinations supplemented to different substrates on in vitro fermentation, ruminal methanogenesis, and abundance and diversity of microbial populations. Journal of Applied Microbiology 119, 127-138. http://dx.doi.org/10.1111/jam.12819

Penn-Nicholson A, Geldenhuys H, Burny W, van der Most R, Day CL, Jongert E, Moris P, Hatherill M, Ofori-Anyinam O, Hanekom W, Bollaerts A, Demoitie M-A, Kany Luabeya AK, De Ruymaeker E, Tameris M, Lapierre D and Scriba TJ (2015) Safety and immunogenicity of candidate vaccine M72/AS01E in adolescents in a TB endemic setting. Vaccine 33, 4025-4034. http://www.sciencedirect.com/science/article/pii/S0264410X15007616

Pirondini M, Colombini S, Malagutti L, Rapetti L, Galassi G, Zanchi R and Crovetto GM (2015) Effects of a selection of additives on in vitro ruminal methanogenesis and in situ and in vivoNDF digestibility. Animal Science Journal 86, 59-68. http://dx.doi.org/10.1111/asj.12249

Rahmanian N, Jafari SM and Wani TA (2015) Bioactive profile, dehydration, extraction and application of the bioactive components of olive leaves. Trends in Food Science & Technology 42, 150-172. http://www.sciencedirect.com/science/article/pii/S0924224415000230

Ramirez-Montagut T (2015) Chapter 15 - Cancer Vaccines. In Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies. (Ed.^(Eds  pp. 365-388. (Academic Press: San Diego). http://www.sciencedirect.com/science/article/pii/B9780124166035000158

Reichert CL, Salminen H, Leuenberger BH, Hinrichs J and Weiss J (2015) Miscibility of Quillaja Saponins with other Co-surfactants under Different pH Values. Journal of Food Science 80, E2495-E2503. http://dx.doi.org/10.1111/1750-3841.13097

Reim V and Rohn S (2015) Characterization of saponins in peas (Pisum sativum L.) by HPTLC coupled to mass spectrometry and a hemolysis assay. Food Research International 76, Part 1, 3-10. http://www.sciencedirect.com/science/article/pii/S0963996914004487

Ribeiro BD, Barreto DW and Coelho MAZ (2015) Use of micellar extraction and cloud point preconcentration for valorization of saponins from sisal (Agave sisalana) waste. Food and Bioproducts Processing 94, 601-609. http://www.sciencedirect.com/science/article/pii/S0960308514000777

Rira M, Chentli A, Boufenera S and Bousseboua H (2015) Effects of Plants Containing Secondary Metabolites on Ruminal Methanogenesis of Sheep in vitro. Energy Procedia 74, 15-24. http://www.sciencedirect.com/science/article/pii/S1876610215012813

Root-Bernstein M and Jaksic FM (2015) Ecosystem process interactions between central Chilean habitats. Global Ecology and Conservation 3, 776-788. http://www.sciencedirect.com/science/article/pii/S2351989415000438

Samoylov A, Cochran A, Schemera B, Kutzler M, Donovan C, Petrenko V, Bartol F and Samoylova T (2015) Humoral immune responses against gonadotropin releasing hormone elicited by immunization with phage-peptide constructs obtained via phage display. Journal of Biotechnology 216, 20-28. http://www.sciencedirect.com/science/article/pii/S0168165615301498

Scognamiglio M, Severino V, D’Abrosca B, Chambery A and Fiorentino A (2015) Chapter 4 - Structural Elucidation of Saponins: A Combined Approach Based on High-Resolution Spectroscopic Techniques. In Studies in Natural Products Chemistry. (Ed.^(Eds Atta ur R) pp. 85-120. (Elsevier). http://www.sciencedirect.com/science/article/pii/B9780444634733000046

Segal L, Morelle D, Blee M, Moore E, Damsten M, Liu KC, Destexhe E and Garçon N (2015) Local tolerance and systemic toxicity of single and repeated intramuscular administrations of two different formulations of the RTS,S malaria candidate vaccine in rabbits. Regulatory Toxicology and Pharmacology 71, 269-278. http://www.sciencedirect.com/science/article/pii/S0273230014003390

Segal L, Roger V, Williams C, Destexhe E and Garçon N (2015) Effects of Adjuvant Systems on the cardiovascular and respiratory functions in telemetered conscious dogs and anaesthetised rats. Regulatory Toxicology and Pharmacology 73, 116-125. http://www.sciencedirect.com/science/article/pii/S0273230015001506

Soema PC, Kompier R, Amorij J-P and Kersten GFA (2015) Current and next generation influenza vaccines: Formulation and production strategies. European Journal of Pharmaceutics and Biopharmaceutics 94, 251-263. http://www.sciencedirect.com/science/article/pii/S0939641115002556

Szumacher-Strabel M, El-Sherbiny M, Cieslak A, Szczechowiak J and Winiarska H (2015) Bioactive lipid components from ruminant milk and meat. In Biotechnology of Bioactive Compounds. (Ed.^(Eds  pp. 599-629. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9781118733103.ch25

Thakur A, Kaur H and Kaur S (2015) Evaluation of the immunoprophylactic potential of a killed vaccine candidate in combination with different adjuvants against murine visceral leishmaniasis. Parasitology International 64, 70-78. http://www.sciencedirect.com/science/article/pii/S1383576914001391

Tironi M and Farías I (2015) Building a park, immunising life: Environmental management and radical asymmetry. Geoforum 66, 167-175. http://www.sciencedirect.com/science/article/pii/S0016718515001116

Uesugi A (2015) The slow-growth high-mortality hypothesis: direct experimental support in a leafmining fly. Ecological Entomology 40, 221-228. http://dx.doi.org/10.1111/een.12177

Valenzuela-Barra G, Castro C, Figueroa C, Barriga A, Silva X, de las Heras B, Hortelano S and Delporte C (2015) Anti-inflammatory activity and phenolic profile of propolis from two locations in Región Metropolitana de Santiago, Chile. Journal of Ethnopharmacology 168, 37-44. http://www.sciencedirect.com/science/article/pii/S0378874115002020

Van Hai N (2015) The use of medicinal plants as immunostimulants in aquaculture: A review. Aquaculture 446, 88-96. http://www.sciencedirect.com/science/article/pii/S0044848615001532

Vicente B, López-Abán J, Rojas-Caraballo J, del Olmo E, Fernández-Soto P, Ramajo-Martín V and Muro A (2015) The combination of the aliphatic diamine AA0029 in ADAD vaccination system with a recombinant fatty acid binding protein could be a good alternative for the animal schistosomiasis control. Experimental Parasitology 154, 134-142. http://www.sciencedirect.com/science/article/pii/S0014489415001204

Zhang J, Bing L and Reineccius GA (2015) Formation, optical property and stability of orange oil nanoemulsions stabilized by Quallija saponins. LWT - Food Science and Technology 64, 1063-1070. http://www.sciencedirect.com/science/article/pii/S0023643815300517

Zhang TT, Zhao GY, Zheng WS, Niu WJ, Wei C and Lin SX (2015) Effects of rare earth element lanthanum on rumen methane and volatile fatty acid production and microbial flora in vitro. Journal of Animal Physiology and Animal Nutrition 99, 442-448. http://dx.doi.org/10.1111/jpn.12251

Zhang Z, Bo T, Bai Y, Ye M, An R, Cheng F and Liu H (2015) Quadrupole time-of-flight mass spectrometry as a powerful tool for demystifying traditional Chinese medicine. TrAC Trends in Analytical Chemistry 72, 169-180. http://www.sciencedirect.com/science/article/pii/S0165993615001879

Abarghuei MJ, Rouzbehan Y, Salem AZM and Zamiri MJ (2014) Nitrogen balance, blood metabolites and milk fatty acid composition of dairy cows fed pomegranate-peel extract. Livestock Science 164, 72-80. http://www.sciencedirect.com/science/article/pii/S1871141314001735

Alving CR, Matyas GR, Torres O, Jalah R and Beck Z (2014) Adjuvants for vaccines to drugs of abuse and addiction. Vaccine 32, 5382-5389. http://www.sciencedirect.com/science/article/pii/S0264410X14010676

Amedei A and Niccolai E (2014) Plant and Marine Sources. In Natural Products Analysis. (Ed.^(Eds  pp. 43-113. (John Wiley & Sons, Inc). http://dx.doi.org/10.1002/9781118876015.ch4

Arslan I (2014) Chapter 12 - Saponins Produced by Gypsophila Species Enhance the Toxicity of Type I Ribosome-Inactivating Proteins. In Studies in Natural Products Chemistry. (Ed.^(Eds Atta ur R) pp. 375-380. (Elsevier). http://www.sciencedirect.com/science/article/pii/B9780444634306000126

Awasthi S and Friedman HM (2014) Status of prophylactic and therapeutic genital herpes vaccines. Current Opinion in Virology 6, 6-12. http://www.sciencedirect.com/science/article/pii/S187962571400039X

Bachran C, Bachran S, Sutherland M, Bachran D and Fuchs H (2014) Chapter 9 - Preclinical Studies of Saponins for Tumor Therapy. In Recent Advances in Medicinal Chemistry. (Ed.^(Eds  pp. 272-302. (Elsevier). http://www.sciencedirect.com/science/article/pii/B9780128039618500099

Barhate G, Gautam M, Gairola S, Jadhav S and Pokharkar V (2014) Enhanced Mucosal Immune Responses Against Tetanus Toxoid Using Novel Delivery System Comprised of Chitosan-Functionalized Gold Nanoparticles and Botanical Adjuvant: Characterization, Immunogenicity, and Stability Assessment. Journal of Pharmaceutical Sciences 103, 3448-3456. http://dx.doi.org/10.1002/jps.24161

Becker JO (2014) Plant Health Management: Crop Protection with Nematicides A2 - Alfen, Neal K. Van. In Encyclopedia of Agriculture and Food Systems. (Ed.^(Eds  pp. 400-407. (Academic Press: Oxford). http://www.sciencedirect.com/science/article/pii/B9780444525123001807

Bitencourt RG, Queiroga CL, Montanari Junior Í and Cabral FA (2014) Fractionated extraction of saponins from Brazilian ginseng by sequential process using supercritical CO2, ethanol and water. The Journal of Supercritical Fluids 92, 272-281. http://www.sciencedirect.com/science/article/pii/S089684461400165X

Bras-Gonçalves R, Petitdidier E, Pagniez J, Veyrier R, Cibrelus P, Cavaleyra M, Maquaire S, Moreaux J and Lemesre J-L (2014) Identification and characterization of new Leishmania promastigote surface antigens, LaPSA-38S and LiPSA-50S, as major immunodominant excreted/secreted components of L. amazonensis and L. infantum. Infection, Genetics and Evolution 24, 1-14. http://www.sciencedirect.com/science/article/pii/S1567134814000823

Brito CE, Bown HE, Fuentes J-P, Franck N and Perez-Quezada JF (2014) Mesophyll conductance constrains photosynthesis in three common sclerophyllous species in Central Chile. Revista chilena de historia natural. 87, 8. http://dx.doi.org/10.1186/s40693-014-0008-0

Brogna DMR, Tansawat R, Cornforth D, Ward R, Bella M, Luciano G, Priolo A and Villalba J (2014) The quality of meat from sheep treated with tannin- and saponin-based remedies as a natural strategy for parasite control. Meat Science 96, 744-749. http://www.sciencedirect.com/science/article/pii/S0309174013005779

Chakraborty SB, Horn P and Hancz C (2014) Application of phytochemicals as growth-promoters and endocrine modulators in fish culture. Reviews in Aquaculture 6, 1-19. http://dx.doi.org/10.1111/raq.12021

Chen X (2014) Profiling and Characterization of Bioactive Substances of Herbal Medicine and their Metabolites Using Mass Spectrometry. In Handbook of Metabolic Pathways of Xenobiotics. (Ed.^(Eds  pp. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9781118541203.xen0032

Cheok CY, Salman HAK and Sulaiman R (2014) Extraction and quantification of saponins: A review. Food Research International 59, 16-40. http://www.sciencedirect.com/science/article/pii/S096399691400074X

Chlibek R, Smetana J, Pauksens K, Rombo L, Van den Hoek JAR, Richardus JH, Plassmann G, Schwarz TF, Ledent E and Heineman TC (2014) Safety and immunogenicity of three different formulations of an adjuvanted varicella-zoster virus subunit candidate vaccine in older adults: A phase II, randomized, controlled study. Vaccine 32, 1745-1753. http://www.sciencedirect.com/science/article/pii/S0264410X14000516

Coleman CM, Liu YV, Mu H, Taylor JK, Massare M, Flyer DC, Glenn GM, Smith GE and Frieman MB (2014) Purified coronavirus spike protein nanoparticles induce coronavirus neutralizing antibodies in mice. Vaccine 32, 3169-3174. http://www.sciencedirect.com/science/article/pii/S0264410X14005180

DSouza DH (2014) Phytocompounds for the control of human enteric viruses. Current Opinion in Virology 4, 44-49. http://www.sciencedirect.com/science/article/pii/S1879625713002113

Du J-R, Long F-Y and Chen C (2014) Chapter Six - Research Progress on Natural Triterpenoid Saponins in the Chemoprevention and Chemotherapy of Cancer. In The Enzymes. (Ed.^(Eds Bathaie SZ and Fuyuhiko T) pp. 95-130. (Academic Press). http://www.sciencedirect.com/science/article/pii/B9780128022153000069

Fernández-Tejada A, Chea EK, George C, Gardner JR, Livingston PO, Ragupathi G, Tan DS and Gin DY (2014) Design, synthesis, and immunologic evaluation of vaccine adjuvant conjugates based on QS-21 and tucaresol. Bioorganic & Medicinal Chemistry 22, 5917-5923. http://www.sciencedirect.com/science/article/pii/S096808961400652X

Fossum C, Hjertner B, Ahlberg V, Charerntantanakul W, McIntosh K, Fuxler L, Balagunaseelan N, Wallgren P and Lövgren Bengtsson K (2014) Early inflammatory response to the saponin adjuvant Matrix-M in the pig. Veterinary Immunology and Immunopathology 158, 53-61. http://www.sciencedirect.com/science/article/pii/S0165242713002183

Fredes C, Yousef GG, Robert P, Grace MH, Lila MA, Gómez M, Gebauer M and Montenegro G (2014) Anthocyanin profiling of wild maqui berries (Aristotelia chilensis [Mol.] Stuntz) from different geographical regions in Chile. Journal of the Science of Food and Agriculture 94, 2639-2648. http://dx.doi.org/10.1002/jsfa.6602

Garg NK, Dwivedi P, Jain A, Tyagi S, Sahu T and Tyagi RK (2014) Development of novel carrier(s) mediated tuberculosis vaccine: More than a tour de force. European Journal of Pharmaceutical Sciences 62, 227-242. http://www.sciencedirect.com/science/article/pii/S0928098714002577

Gu G, An L, Fang M and Guo Z (2014) Efficient one-pot synthesis of tigogenin saponins and their antitumor activities. Carbohydrate Research 383, 21-26. http://www.sciencedirect.com/science/article/pii/S0008621513003868

Guo X, Zhang X, Guo Z, Liu Y, Shen A, Jin G and Liang X (2014) Hydrophilic interaction chromatography for selective separation of isomeric saponins. Journal of Chromatography A 1325, 121-128. http://www.sciencedirect.com/science/article/pii/S0021967313018700

Güroy B, Mantoğlu S, Kayalı S and Şahin İ (2014) Effect of dietary Yucca schidigera extract on growth, total ammonia–nitrogen excretion and haematological parameters of juvenile striped catfish Pangasianodon hypophthalmus. Aquaculture Research 45, 647-654. http://dx.doi.org/10.1111/are.12001

Gusiatin ZM (2014) Tannic acid and saponin for removing arsenic from brownfield soils: Mobilization, distribution and speciation. Journal of Environmental Sciences 26, 855-864. http://www.sciencedirect.com/science/article/pii/S1001074213605343

Harrer T, Plettenberg A, Arastéh K, Van Lunzen J, Fätkenheuer G, Jaeger H, Janssens M, Burny W, Collard A, Roman F, Loeliger A, Koutsoukos M, Bourguignon P, Lavreys L and Voss G (2014) Safety and immunogenicity of an adjuvanted protein therapeutic HIV-1 vaccine in subjects with HIV-1 infection: A randomised placebo-controlled study. Vaccine 32, 2657-2665. http://www.sciencedirect.com/science/article/pii/S0264410X13014060

Idoko OT, Owolabi OA, Owiafe PK, Moris P, Odutola A, Bollaerts A, Ogundare E, Jongert E, Demoitié M-A, Ofori-Anyinam O and Ota MO (2014) Safety and immunogenicity of the M72/AS01 candidate tuberculosis vaccine when given as a booster to BCG in Gambian infants: An open-label randomized controlled trial. Tuberculosis 94, 564-578. http://www.sciencedirect.com/science/article/pii/S1472979214204227

Jiang W, Chen S-Y, Wang H, Li D-Z and Wiens JJ (2014) Should genes with missing data be excluded from phylogenetic analyses? Molecular Phylogenetics and Evolution 80, 308-318. http://www.sciencedirect.com/science/article/pii/S1055790314002735

Kezwon A and Wojciechowski K (2014) Interaction of Quillaja bark saponins with food-relevant proteins. Advances in Colloid and Interface Science 209, 185-195. http://www.sciencedirect.com/science/article/pii/S0001868614001419

Kraft JC, Freeling JP, Wang Z and Ho RJY (2014) Emerging Research and Clinical Development Trends of Liposome and Lipid Nanoparticle Drug Delivery Systems. Journal of Pharmaceutical Sciences 103, 29-52. http://www.sciencedirect.com/science/article/pii/S0022354915307814

Liu Y, Xu Y, Tian Y, Chen C, Wang C and Jiang X (2014) Functional Nanomaterials Can Optimize the Efficacy of Vaccines. Small 10, 4505-4520. http://dx.doi.org/10.1002/smll.201401707

Magnusson SE, Karlsson KH, Reimer JM, Corbach-Söhle S, Patel S, Richner JM, Nowotny N, Barzon L, Bengtsson KL, Ulbert S, Diamond MS and Stertman L (2014) Matrix-M™ adjuvanted envelope protein vaccine protects against lethal lineage 1 and 2 West Nile virus infection in mice. Vaccine 32, 800-808. http://www.sciencedirect.com/science/article/pii/S0264410X13017611

Mandal GP, Roy A and Patra AK (2014) Effects of feeding plant additives rich in saponins and essential oils on the performance, carcass traits and conjugated linoleic acid concentrations in muscle and adipose tissues of Black Bengal goats. Animal Feed Science and Technology 197, 76-84. http://www.sciencedirect.com/science/article/pii/S0377840114002776

Marciani DJ (2014) New Th2 adjuvants for preventive and active immunotherapy of neurodegenerative proteinopathies. Drug Discovery Today 19, 912-920. http://www.sciencedirect.com/science/article/pii/S1359644614000774

Mody KT, Mahony D, Zhang J, Cavallaro AS, Zhang B, Popat A, Mahony TJ, Yu C and Mitter N (2014) Silica vesicles as nanocarriers and adjuvants for generating both antibody and T-cell mediated immune resposes to Bovine Viral Diarrhoea Virus E2 protein. Biomaterials 35, 9972-9983. http://www.sciencedirect.com/science/article/pii/S0142961214009818

Nico D, Morrot A and Palatnik-de-Sousa CB (2014) Vaccination with Nucleoside Hydrolase (NH36) of L.(L.) Donovani or its C-terminal Portion (F3) in Formulation with Saponin Prevents the Increase of the Proportions of Spleen Dendritic Cells in Murine Experimental Visceral Leishmaniasis. Procedia in Vaccinology 8, 58-61. http://www.sciencedirect.com/science/article/pii/S1877282X14000113

Olivera-Guerra L, Mattar C and Galleguillos M (2014) Estimation of real evapotranspiration and its variation in Mediterranean landscapes of central-southern Chile. International Journal of Applied Earth Observation and Geoinformation 28, 160-169. http://www.sciencedirect.com/science/article/pii/S0303243413001657

Ozturk B, Argin S, Ozilgen M and McClements DJ (2014) Formation and stabilization of nanoemulsion-based vitamin E delivery systems using natural surfactants: Quillaja saponin and lecithin. Journal of Food Engineering 142, 57-63. http://www.sciencedirect.com/science/article/pii/S0260877414002568

Paepenmüller T and Müller-Goymann CC (2014) Influence of Quil A on liposomal membranes. International Journal of Pharmaceutics 475, 138-146. http://www.sciencedirect.com/science/article/pii/S0378517314005626

Pan L, Terrazas C, Acuńa UM, Ninh TN, Chai H, Carcache de Blanco EJ, Soejarto DD, Satoskar AR and Kinghorn AD (2014) Bioactive indole alkaloids isolated from Alstonia angustifolia. Phytochemistry Letters 10, liv-lix. http://www.sciencedirect.com/science/article/pii/S1874390014001086

Paniwnyk L (2014) Chapter 15 - Application of Ultrasound A2 - Sun, Da-Wen. In Emerging Technologies for Food Processing (Second Edition). (Ed.^(Eds  pp. 271-291. (Academic Press: San Diego). http://www.sciencedirect.com/science/article/pii/B9780124114791000152

Patra AK and Yu Z (2014) Combinations of nitrate, saponin, and sulfate additively reduce methane production by rumen cultures in vitro while not adversely affecting feed digestion, fermentation or microbial communities. Bioresource Technology 155, 129-135. http://www.sciencedirect.com/science/article/pii/S0960852413019391

Piorkowski DT and McClements DJ (2014) Beverage emulsions: Recent developments in formulation, production, and applications. Food Hydrocolloids 42, Part 1, 5-41. http://www.sciencedirect.com/science/article/pii/S0268005X13002117

Pouliot K, Buglione-Corbett R, Marty-Roix R, Montminy-Paquette S, West K, Wang S, Lu S and Lien E (2014) Contribution of TLR4 and MyD88 for adjuvant monophosphoryl lipid A (MPLA) activity in a DNA prime–protein boost HIV-1 vaccine. Vaccine 32, 5049-5056. http://www.sciencedirect.com/science/article/pii/S0264410X14009360

Priddy TS, Middaugh CR, P. Wen E, Ellis R and S. Pujar N (2014) Stabilization and Formulation of Vaccines. In Vaccine Development and Manufacturing. (Ed.^(Eds  pp. 237-261. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118870914.ch8

Puleio R, Antoci F, Tumino G, Tamburello A, Di Marco P, Purpari G, Guercio A and Loria GR (2014) Detection of Bovine Papillomavirus and Efficacy of Treatment Using Saponin. Journal of Comparative Pathology 150, 97. http://www.sciencedirect.com/science/article/pii/S0021997513002570

Qiao N, Liu Q, Meng H and Zhao D (2014) Haemolytic activity and adjuvant effect of soyasaponins and some of their derivatives on the immune responses to ovalbumin in mice. International Immunopharmacology 18, 333-339. http://www.sciencedirect.com/science/article/pii/S1567576913005067

Quirici V, Venegas CI, González-Gómez PL, Castańo-Villa GJ, Wingfield JC and Vásquez RA (2014) Baseline corticosterone and stress response in the Thorn-tailed Rayadito (Aphrastura spinicauda) along a latitudinal gradient. General and Comparative Endocrinology 198, 39-46. http://www.sciencedirect.com/science/article/pii/S001664801300484X

Ren J, Lu H, Wen S, Sun W, Yan F, Chen X, Jing J, Liu H, Liu C, Xue F, Xiao P, Xin S and Jin N (2014) Enhanced immune responses in pigs by DNA vaccine coexpressing GP3 and GP5 of European type porcine reproductive and respiratory syndrome virus. Journal of Virological Methods 206, 27-37. http://www.sciencedirect.com/science/article/pii/S0166093414002134

Rodrigues MM and Soares IS (2014) Gene-therapy for malaria prevention. Trends in Parasitology 30, 511-513. http://www.sciencedirect.com/science/article/pii/S1471492214001627

Salminen H, Aulbach S, Leuenberger BH, Tedeschi C and Weiss J (2014) Influence of surfactant composition on physical and oxidative stability of Quillaja saponin-stabilized lipid particles with encapsulated ω-3 fish oil. Colloids and Surfaces B: Biointerfaces 122, 46-55. http://www.sciencedirect.com/science/article/pii/S0927776514003385

Shi YH, Wang J, Guo R, Wang CZ, Yan XB, Xu B and Zhang DQ (2014) Effects of alfalfa saponin extract on growth performance and some antioxidant indices of weaned piglets. Livestock Science 167, 257-262. http://www.sciencedirect.com/science/article/pii/S1871141314003047

Skinner HCW and Ehrlich H (2014) 10.4 - Biomineralization A2 - Holland, Heinrich D. In Treatise on Geochemistry (Second Edition). (Ed.^(Eds Turekian KK) pp. 105-162. (Elsevier: Oxford). http://www.sciencedirect.com/science/article/pii/B9780080959757008044

Sun H, He S and Shi M (2014) Adjuvant-active fraction from Albizia julibrissin saponins improves immune responses by inducing cytokine and chemokine at the site of injection. International Immunopharmacology 22, 346-355. http://www.sciencedirect.com/science/article/pii/S1567576914002872

Thalhamer B and Himmelsbach M (2014) Characterization of quillaja bark extracts and evaluation of their purity using liquid chromatography–high resolution mass spectrometry. Phytochemistry Letters 8, 97-100. http://www.sciencedirect.com/science/article/pii/S1874390014000378

Thalhamer B and Himmelsbach M (2014) Characterization of quillaja bark extracts and evaluation of their purity using liquid chromatography–high resolution mass spectrometry. Phytochemistry letters., 8. http://dx.doi.org/10.1016/j.phytol.2014.02.009

Tong T, Crooks ET, Osawa K, Robinson JE, Barnes M, Apetrei C and Binley JM (2014) Multi-parameter exploration of HIV-1 virus-like particles as neutralizing antibody immunogens in guinea pigs, rabbits and macaques. Virology 456–457, 55-69. http://www.sciencedirect.com/science/article/pii/S004268221400097X

Umeh R, Oguche S, Oguonu T, Pitmang S, Shu E, Onyia J-T, Daniyam CA, Shwe D, Ahmad A, Jongert E, Catteau G, Lievens M, Ofori-Anyinam O and Leach A (2014) Immunogenicity and safety of the candidate RTS,S/AS01 vaccine in young Nigerian children: A randomized, double-blind, lot-to-lot consistency trial. Vaccine 32, 6556-6562. http://www.sciencedirect.com/science/article/pii/S0264410X14010196

Van Damme P, Leroux-Roels G, Simon P, Foidart J-M, Donders G, Hoppenbrouwers K, Levin M, Tibaldi F, Poncelet S, Moris P, Dessy F, Giannini SL, Descamps D and Dubin G (2014) Effects of varying antigens and adjuvant systems on the immunogenicity and safety of investigational tetravalent human oncogenic papillomavirus vaccines: Results from two randomized trials. Vaccine 32, 3694-3705. http://www.sciencedirect.com/science/article/pii/S0264410X14004095

van de Sandt CE, Kreijtz JHCM, Geelhoed-Mieras MM, Trierum SEV-v, Nieuwkoop NJ, van de Vijver DAMC, Fouchier RAM, Osterhaus ADME, Morein B and Rimmelzwaan GF (2014) Novel G3/DT adjuvant promotes the induction of protective T cells responses after vaccination with a seasonal trivalent inactivated split-virion influenza vaccine. Vaccine 32, 5614-5623. http://www.sciencedirect.com/science/article/pii/S0264410X14011165

Vicente B, López-Abán J, Rojas-Caraballo J, Pérez del Villar L, Hillyer GV, Martínez-Fernández AR and Muro A (2014) A Fasciola hepatica-derived fatty acid binding protein induces protection against schistosomiasis caused by Schistosoma bovis using the adjuvant adaptation (ADAD) vaccination system. Experimental Parasitology 145, 145-151. http://www.sciencedirect.com/science/article/pii/S0014489414001970

Vinay T-N, Park C-S, Kim H-Y and Jung S-J (2014) Toxicity and dose determination of quillaja saponin, aluminum hydroxide and squalene in olive flounder (Paralichthys olivaceus). Veterinary Immunology and Immunopathology 158, 73-85. http://www.sciencedirect.com/science/article/pii/S0165242713001128

Wojciechowski K, Kezwon A, Lewandowska J and Marcinkowski K (2014) Effect of β-casein on surface activity of Quillaja bark saponin at fluid/fluid interfaces. Food Hydrocolloids 34, 208-216. http://www.sciencedirect.com/science/article/pii/S0268005X12002068

Wojciechowski K, Orczyk M, Gutberlet T, Trapp M, Marcinkowski K, Kobiela T and Geue T (2014) Unusual penetration of phospholipid mono- and bilayers by Quillaja bark saponin biosurfactant. Biochimica et Biophysica Acta (BBA) - Biomembranes 1838, 1931-1940. http://www.sciencedirect.com/science/article/pii/S0005273614001436

Wojciechowski K, Orczyk M, Marcinkowski K, Kobiela T, Trapp M, Gutberlet T and Geue T (2014) Effect of hydration of sugar groups on adsorption of Quillaja bark saponin at air/water and Si/water interfaces. Colloids and Surfaces B: Biointerfaces 117, 60-67. http://www.sciencedirect.com/science/article/pii/S0927776514000770

Wylie CE, Carbonell-Antońanzas M, Aiassa E, Dhollander S, Zagmutt FJ, Brodbelt DC and Solano-Gallego L (2014) A systematic review of the efficacy of prophylactic control measures for naturally-occurring canine leishmaniosis, part I: Vaccinations. Preventive Veterinary Medicine 117, 7-18. http://www.sciencedirect.com/science/article/pii/S016758771400213X

Xiang X-G, Wang W, Li R-Q, Lin L, Liu Y, Zhou Z-K, Li Z-Y and Chen Z-D (2014) Large-scale phylogenetic analyses reveal fagalean diversification promoted by the interplay of diaspores and environments in the Paleogene. Perspectives in Plant Ecology, Evolution and Systematics 16, 101-110. http://www.sciencedirect.com/science/article/pii/S1433831914000201

Yang Y, Laval S and Yu B (2014) Chapter 2 - Chemical Synthesis of Saponins. In Advances in Carbohydrate Chemistry and Biochemistry. (Ed.^(Eds Derek H) pp. 137-226. (Academic Press). http://www.sciencedirect.com/science/article/pii/B9780128001288000029

(2013) Index A2 - Grebner, Donald L. In Introduction to Forestry and Natural Resources. (Ed.^(Eds Bettinger P and Siry JP) pp. 479-496. (Academic Press: San Diego). http://www.sciencedirect.com/science/article/pii/B9780123869012180017

Acharjee S and Sarmah BK (2013) Biotechnologically generating ‘super chickpea’ for food and nutritional security. Plant Science 207, 108-116. http://www.sciencedirect.com/science/article/pii/S0168945213000344

Arslan I and Çelik A (2013) Saponin Rich Fractions (SRPs) from Soapwort Show Antioxidant and Hemolytic Activity. APCBEE Procedia 7, 103-108. http://www.sciencedirect.com/science/article/pii/S2212670813001218

Ballou WR and Cohen J (2013) 53 - Malaria vaccines A2 - Plotkin, Stanley A. In Vaccines (Sixth Edition). (Ed.^(Eds Orenstein WA and Offit PA) pp. 1133-1137. (W.B. Saunders: London). http://www.sciencedirect.com/science/article/pii/B9781455700905000562

Bastos BL, Loureiro D, Raynal JT, Guedes MT, Vale VLC, Moura-Costa LF, Guimarăes JE, Azevedo V, Portela RW and Meyer R (2013) Association between haptoglobin and IgM levels and the clinical progression of caseous lymphadenitis in sheep. BMC veterinary research. 9, 815. http://dx.doi.org/10.1186/1746-6148-9-254

Batista-Duharte A, Portuondo D, Carlos IZ and Pérez O (2013) An approach to local immunotoxicity induced by adjuvanted vaccines. International Immunopharmacology 17, 526-536. http://www.sciencedirect.com/science/article/pii/S1567576913003123

Becerra PI and Montenegro G (2013) The widely invasive tree Pinus radiata facilitates regeneration of native woody species in a semi-arid ecosystem. Applied Vegetation Science 16, 173-183. http://dx.doi.org/10.1111/j.1654-109X.2012.01221.x

Beckebaum S, Kabar I and Cicinnati VR (2013) Hepatitis B and C in liver transplantation: new strategies to combat the enemies. Reviews in Medical Virology 23, 172-193. http://dx.doi.org/10.1002/rmv.1734

Beerling J (2013) Green Formulations and Ingredients. In Sustainability: How the Cosmetics Industry is Greening Up. (Ed.^(Eds  pp. 197-215. (John Wiley & Sons Ltd). http://dx.doi.org/10.1002/9781118676516.ch9

Chakraborty S, Singha S, Bhattacharya K and Chandra G (2013) Control of human filarial vector, Culex quinquefasciatus Say 1823 (Diptera: Culicidae) through bioactive fraction of Cayratia trifolia leaf. Asian Pacific Journal of Tropical Biomedicine 3, 980-984. http://www.sciencedirect.com/science/article/pii/S2221169113601896

Chlibek R, Bayas JM, Collins H, de la Pinta MLR, Ledent E, Mols JF and Heineman TC (2013) Safety and Immunogenicity of an AS01-adjuvanted Varicella-zoster Virus Subunit Candidate Vaccine Against Herpes Zoster in Adults >=50 Years of Age. The Journal of Infectious Disease, jit365. http://jid.oxfordjournals.org//cgi/content/abstract/jit365v2

Das BK, Pradhan J, Sahu S, Marhual NP, Mishra BK and Eknath AE (2013) Microcystis aeruginosa (Kütz) incorporated diets increase immunity and survival of Indian major carp Labeo rohita (Ham.) against Aeromonas hydrophila infection. Aquaculture Research 44, 918-927. http://dx.doi.org/10.1111/j.1365-2109.2012.03098.x

de Costa F, Yendo ACA, Fleck JD, Gosmann G and Fett-Neto AG (2013) Accumulation of a bioactive triterpene saponin fraction of Quillaja brasiliensis leaves is associated with abiotic and biotic stresses. Plant physiology and biochemistry., 66. http://dx.doi.org/10.1016/j.plaphy.2013.02.003

Fox CB, Sivananthan SJ, Mikasa TJT, Lin S and Parker SC (2013) Charged aerosol detection to characterize components of dispersed-phase formulations. Advances in Colloid and Interface Science 199–200, 59-65. http://www.sciencedirect.com/science/article/pii/S0001868613000705

Gad HA, El-Ahmady SH, Abou-Shoer MI and Al-Azizi MM (2013) Application of Chemometrics in Authentication of Herbal Medicines: A Review. Phytochemical Analysis 24, 1-24. http://dx.doi.org/10.1002/pca.2378

Garçon N, Hem S and Friede M (2013) 5 - Evolution of adjuvants across the centuries A2 - Plotkin, Stanley A. In Vaccines (Sixth Edition). (Ed.^(Eds Orenstein WA and Offit PA) pp. 58-70. (W.B. Saunders: London). http://www.sciencedirect.com/science/article/pii/B9781455700905000203

Gonzalez-Coloma A, Reina M, Diaz CE, Fraga BM and Santana-Meridas O (2013) Natural Product-Based Biopesticides for Insect Control. In Reference Module in Chemistry, Molecular Sciences and Chemical Engineering. (Ed.^(Eds  pp. (Elsevier). http://www.sciencedirect.com/science/article/pii/B9780124095472027700

Grebner DL, Bettinger P and Siry JP (2013) Chapter 2 - Forest Regions of the World. In Introduction to Forestry and Natural Resources. (Ed.^(Eds  pp. 21-76. (Academic Press: San Diego). http://www.sciencedirect.com/science/article/pii/B9780123869012000026

Groskreutz SR and Stoll DR (2013) Theory and Practice of Two-Dimensional Liquid Chromatography Separations Involving the HILIC Mode of Separation. In Hydrophilic Interaction Chromatography. (Ed.^(Eds  pp. 265-305. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118495247.ch9

Gu G, Zhao Y and Guo Z (2013) Synthesis of Leonosides E and F derived from Leonurus japonicas Houtt. Carbohydrate Research 380, 174-180. http://www.sciencedirect.com/science/article/pii/S0008621513002784

Hamshou M, Van Damme EJM, Caccia S, Cappelle K, Vandenborre G, Ghesquičre B, Gevaert K and Smagghe G (2013) High entomotoxicity and mechanism of the fungal GalNAc/Gal-specific Rhizoctonia solani lectin in pest insects. Journal of Insect Physiology 59, 295-305. http://www.sciencedirect.com/science/article/pii/S0022191012003009

HASSAN SB, GULLBO J, HU K, BERENJIAN S, MOREIN B and NYGREN P (2013) The Nanoparticulate Quillaja Saponin BBE Is Selectively Active Towards Renal Cell Carcinoma. Anticancer Res 33, 143-151. http://ar.iiarjournals.org/cgi/content/abstract/33/1/143

Hearnden C and Lavelle EC (2013) Chapter 21 - Adjuvant Strategies for Vaccines: The Use of Adjuvants within the Cancer Vaccine Setting A2 - Prendergast, George C. In Cancer Immunotherapy (Second Edition). (Ed.^(Eds Jaffee EM) pp. 333-349. (Academic Press: San Diego). http://www.sciencedirect.com/science/article/pii/B978012394296800021X

Khan H, Saeed M, Gilani AH, Muhammad N, Haq I-u, Ashraf N, Rehman N-u and Haleemi A (2013) Antipyretic and Anticonvulsant Activity of Polygonatum verticillatum: Comparison of Rhizomes and Aerial Parts. Phytotherapy Research 27, 468-471. http://dx.doi.org/10.1002/ptr.4721

Koupparis MA, Megoulas NC and Gremilogianni AM (2013) HILIC for Food, Environmental, and Other Applications. In Hydrophilic Interaction Chromatography. (Ed.^(Eds  pp. 239-264. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118495247.ch8

Krawczyk A, Roggendorf H, Ludwig C, Herzer K, Gerken G, Horn PA, Roggendorf M and Lindemann M (2013) Therapeutic vaccination of a liver transplant recipient suffering from fulminant hepatitis B during pregnancy. Liver Transplantation 19, 1411-1412. http://dx.doi.org/10.1002/lt.23751

Lee MH, Lee B-H, Lee S and Choi C (2013) Reduction of Hepatitis A Virus on FRhK-4 Cells Treated with Korean Red Ginseng Extract and Ginsenosides. Journal of Food Science 78, M1412-M1415. http://dx.doi.org/10.1111/1750-3841.12205

Leroux-Roels I, Forgus S, De Boever F, Clement F, Demoitié M-A, Mettens P, Moris P, Ledent E, Leroux-Roels G and Ofori-Anyinam O (2013) Improved CD4+ T cell responses to Mycobacterium tuberculosis in PPD-negative adults by M72/AS01 as compared to the M72/AS02 and Mtb72F/AS02 tuberculosis candidate vaccine formulations: A randomized trial. Vaccine 31, 2196-2206. http://www.sciencedirect.com/science/article/pii/S0264410X12007396

Lewis KA, Tzilivakis J, Green A, Warner DJ, Stedman A and Naseby D (2013) Review of substances/agents that have direct beneficial effect on the environment: mode of action and assessment of efficacy. EFSA Supporting Publications 10, n/a-n/a. http://dx.doi.org/10.2903/sp.efsa.2013.EN-440

Loewe M V, González O M and Balzarini M (2013) Wild cherry tree (Prunus avium L.) growth in pure and mixed plantations in South America. Forest Ecology and Management 306, 31-41. http://www.sciencedirect.com/science/article/pii/S0378112713003836

Luebert F (2013) Taxonomy and distribution of the genus Quillaja Molina (Quillajaceae). Feddes Repertorium 124, 157-162. http://dx.doi.org/10.1002/fedr.201400029

Magnusson SE, Reimer JM, Karlsson KH, Lilja L, Bengtsson KL and Stertman L (2013) Immune enhancing properties of the novel Matrix-M™ adjuvant leads to potentiated immune responses to an influenza vaccine in mice. Vaccine 31, 1725-1733. http://www.sciencedirect.com/science/article/pii/S0264410X13001072

Mahomoodally MF and Gurib-Fakim A (2013) Chapter 15 - Harnessing Traditional Knowledge to Treat Existing and Emerging Infectious Diseases in Africa A2 - Rai, Mahendra Kumar. In Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components. (Ed.^(Eds Kon KV) pp. 223-235. (Academic Press: San Diego). http://www.sciencedirect.com/science/article/pii/B978012398539200015X

Mahony D, Cavallaro AS, Stahr F, Mahony TJ, Qiao SZ and Mitter N (2013) Mesoporous Silica Nanoparticles Act as a Self-Adjuvant for Ovalbumin Model Antigen in Mice. Small 9, 3138-3146. http://dx.doi.org/10.1002/smll.201300012

Moate PJ, Williams SRO, Hannah MC, Eckard RJ, Auldist MJ, Ribaux BE, Jacobs JL and Wales WJ (2013) Effects of feeding algal meal high in docosahexaenoic acid on feed intake, milk production, and methane emissions in dairy cows. Journal of Dairy Science 96, 3177-3188. http://www.sciencedirect.com/science/article/pii/S0022030213001975

Morgavi DP, Martin C and Boudra H (2013) Fungal secondary metabolites from Monascus spp. reduce rumen methane production in vitro and in vivo. J Anim Sci 91, 848-860. http://www.journalofanimalscience.org/cgi/content/abstract/91/2/848

Moses T, Pollier J, Thevelein JM and Goossens A (2013) Bioengineering of plant (tri)terpenoids: from metabolic engineering of plants to synthetic biology in vivo and in vitro. New Phytologist 200, 27-43. http://dx.doi.org/10.1111/nph.12325

Mukherjee C, Mäkinen K, Savolainen J and Leino R (2013) Chemistry and Biology of Oligovalent β-(1→2)-Linked Oligomannosides: New Insights into Carbohydrate-Based Adjuvants in Immunotherapy. Chemistry – A European Journal 19, 7961-7974. http://dx.doi.org/10.1002/chem.201203963

Naseri V, Hozhabri F and Kafilzadeh F (2013) Assessment of in vitro digestibility and fermentation parameters of alfalfa hay-based diet following direct incorporation of fenugreek seed (Trigonella foenum) and asparagus root (Asparagus officinalis). Journal of Animal Physiology and Animal Nutrition 97, 773-784. http://dx.doi.org/10.1111/j.1439-0396.2012.01318.x

Otranto D and Dantas-Torres F (2013) The prevention of canine leishmaniasis and its impact on public health. Trends in Parasitology 29, 339-345. http://www.sciencedirect.com/science/article/pii/S1471492213000755

Patra AK and Yu Z (2013) Effective reduction of enteric methane production by a combination of nitrate and saponin without adverse effect on feed degradability, fermentation, or bacterial and archaeal communities of the rumen. Bioresource Technology 148, 352-360. http://www.sciencedirect.com/science/article/pii/S0960852413013916

Pensec F, Marmonier A, Marchal A, Gersch S, Nassr N, Chong J, Henry M, Demangeat G and Bertsch C (2013) Gypsophila paniculata root saponins as an environmentally safe treatment against two nematodes, natural vectors of grapevine fanleaf degeneration. Australian Journal of Grape and Wine Research 19, 439-445. http://dx.doi.org/10.1111/ajgw.12031

Perry CGR, Kane DA, Lanza IR and Neufer PD (2013) Methods for Assessing Mitochondrial Function in Diabetes. Diabetes 62, 1041-1053. http://diabetes.diabetesjournals.org/cgi/content/abstract/62/4/1041

Quispe-Fuentes I, Vega-GÁLvez A, Miranda M, Lemus-Mondaca R, Lozano M and Ah-Hen K (2013) A KINETIC APPROACH TO SAPONIN EXTRACTION DURING WASHING OF QUINOA (CHENOPODIUM QUINOA WILLD.) SEEDS. Journal of Food Process Engineering 36, 202-210. http://dx.doi.org/10.1111/j.1745-4530.2012.00673.x

Ribeiro BD, Alviano DS, Barreto DW and Coelho MAZ (2013) Functional properties of saponins from sisal (Agave sisalana) and juá (Ziziphus joazeiro): Critical micellar concentration, antioxidant and antimicrobial activities. Colloids and Surfaces A: Physicochemical and Engineering Aspects 436, 736-743. http://www.sciencedirect.com/science/article/pii/S0927775713006092

Scheurer W, Spring P and Maertens L (2013) Effect of 3 dietary phytogenic products on production performance and coccidiosis in challenged broiler chickens. J. Appl. Poult. Res. 22, 591-599. http://japr.fass.org/cgi/content/abstract/22/3/591

Scopel M, dos Santos O, Frasson AP, Abraham W-R, Tasca T, Henriques AT and Macedo AJ (2013) Anti-Trichomonas vaginalis activity of marine-associated fungi from the South Brazilian Coast. Experimental Parasitology 133, 211-216. http://www.sciencedirect.com/science/article/pii/S001448941200344X

Serrano AE (2013) Effects of Quillaja saponins on growth, feed efficiency, digestive enzyme activities and metabolism of common carp (Cyprinus carpio L). Aquaculture Nutrition 19, 468-474. http://dx.doi.org/10.1111/j.1365-2095.2012.00980.x

Silva BPd and Parente JP (2013) A new complex triterpenoid saponin from Calliandra pulcherrima with haemolytic activity and adjuvant effect. Phytochemistry Letters 6, 633-639. http://www.sciencedirect.com/science/article/pii/S1874390013001481

Soroor EN, Rouzbehan Y and Alipour D (2013) Effect of Echium amoenum extract on the growth rate and fermentation parameters of Mehraban lambs. Animal Feed Science and Technology 184, 49-57. http://www.sciencedirect.com/science/article/pii/S0377840113001570

Spertini F, Audran R, Lurati F, Ofori-Anyinam O, Zysset F, Vandepapeličre P, Moris P, Demoitié M-A, Mettens P, Vinals C, Vastiau I, Jongert E, Cohen J and Ballou WR (2013) The candidate tuberculosis vaccine Mtb72F/AS02 in PPD positive adults: A randomized controlled phase I/II study. Tuberculosis 93, 179-188. http://www.sciencedirect.com/science/article/pii/S1472979212001989

Stadtlander T, Levavi-Sivan B, Kerem Z, Dweik H, Qutob M, Abu-Lafi S, Francis G, Focken U and Becker K (2013) Effects of a saponin fraction extracted from Trigonella foenum-graecum L. and two commercially available saponins on sex ratio and gonad histology of Nile tilapa fry, Oreochromis niloticus (L.). Journal of Applied Ichthyology 29, 265-267. http://dx.doi.org/10.1111/jai.12002

Subramaniam A, Veazey RL, Schober A, Rada A, Rong Y, van Sleeuwen RMT, Golding R, Zhang S and Normand V (2013) Orange oil stability in spray dry delivery systems. Carbohydrate Polymers 97, 352-357. http://www.sciencedirect.com/science/article/pii/S0144861713004797

Tafalla C, Břgwald J and Dalmo RA (2013) Adjuvants and immunostimulants in fish vaccines: Current knowledge and future perspectives. Fish & Shellfish Immunology 35, 1740-1750. http://www.sciencedirect.com/science/article/pii/S1050464813000909

Vanloubbeeck Y, Pichyangkul S, Bayat B, Yongvanitchit K, Bennett JW, Sattabongkot J, Schaecher K, Ockenhouse CF, Cohen J and Yadava A (2013) Comparison of the immune responses induced by soluble and particulate Plasmodium vivax circumsporozoite vaccine candidates formulated in AS01 in rhesus macaques. Vaccine 31, 6216-6224. http://www.sciencedirect.com/science/article/pii/S0264410X13014175

Wang Y, Wang X, Huang J and Li J (2013) Adjuvant effects of Quillaja saponaria saponins (QSS) on humoral immune responses in turbot. Fish & Shellfish Immunology 34, 1745. http://www.sciencedirect.com/science/article/pii/S105046481300435X

Weniger BG and Papania MJ (2013) 61 - Alternative vaccine delivery methods A2 - Plotkin, Stanley A. In Vaccines (Sixth Edition). (Ed.^(Eds Orenstein WA and Offit PA) pp. 1200-1231. (W.B. Saunders: London). http://www.sciencedirect.com/science/article/pii/B978145570090500063X

Yang Y, Leser ME, Sher AA and McClements DJ (2013) Formation and stability of emulsions using a natural small molecule surfactant: Quillaja saponin (Q-Naturale®). Food Hydrocolloids 30, 589-596. http://www.sciencedirect.com/science/article/pii/S0268005X12001804

Zöllner T and Schwarz M (2013) Herbal Reference Standards: applications, definitions and regulatory requirements. Revista Brasileira de Farmacognosia 23, 1-21. http://www.sciencedirect.com/science/article/pii/S0102695X13700012

Ahlberg V, Lövgren Bengtsson K, Wallgren P and Fossum C (2012) Global transcriptional response to ISCOM-Matrix adjuvant at the site of administration and in the draining lymph node early after intramuscular injection in pigs. Developmental &amp; Comparative Immunology 38, 17-26. http://www.sciencedirect.com/science/article/pii/S0145305X12000432

Ahmed FK, Clark BE, Burton DR and Pantophlet R (2012) An engineered mutant of HIV-1 gp120 formulated with adjuvant Quil A promotes elicitation of antibody responses overlapping the CD4-binding site. Vaccine 30, 922-930. http://www.sciencedirect.com/science/article/pii/S0264410X11018858

ALI R, MIRZA Z, ASHRAF GMD, KAMAL MA, ANSARI SA, DAMANHOURI GA, ABUZENADAH AM, CHAUDHARY AG and SHEIKH IA (2012) New Anticancer Agents: Recent Developments in Tumor Therapy. Anticancer Res 32, 2999-3005. http://ar.iiarjournals.org/cgi/content/abstract/32/7/2999

Arabski M, Wegierek-Ciuk A, Czerwonka G, Lankoff A and Kaca W (2012) Effects of saponins against clinical E. coli strains and eukaryotic cell line. J Biomed Biotechnol 2012, 286216.

Augustin JM, Drok S, Shinoda T, Sanmiya K, Nielsen JK, Khakimov B, Olsen CE, Hansen EH, Kuzina V, Ekstrom CT, Hauser T and Bak S (2012) UDP-Glycosyltransferases from the UGT73C Subfamily in Barbarea vulgaris Catalyze Sapogenin 3-O-Glucosylation in Saponin-Mediated Insect Resistance. Plant Physiology 160, 1881-1895. http://www.plantphysiol.org/cgi/content/abstract/160/4/1881

Barbosa AdP, da Silva BP and Parente JP (2012) A new complex triterpenoid saponin from Samanea saman with haemolytic activity and adjuvant effect. Phytochemistry Letters 5, 626-631. http://www.sciencedirect.com/science/article/pii/S187439001200122X

Barhate G, Gautam M, Gairola S, Jadhav S and Pokharkar V (2012) Quillaja saponaria extract as mucosal adjuvant with chitosan functionalized gold nanoparticles for mucosal vaccine delivery: Stability and immunoefficiency studies. Int J Pharm.

Baz Morelli A, Becher D, Koernig S, Silva A, Drane D and Maraskovsky E (2012) ISCOMATRIX: a novel adjuvant for use in prophylactic and therapeutic vaccines against infectious diseases. J. Med. Microbiol. 61, 935-943. http://jmm.sgmjournals.org/cgi/content/abstract/61/Pt_7/935

Becerra PI and Montenegro G (2012) The widely invasive tree Pinus radiata facilitates regeneration of native woody species in a semi-arid ecosystem. Applied Vegetation Science, n/a-n/a. http://dx.doi.org/10.1111/j.1654-109X.2012.01221.x

Bello MA, Rudall PJ and Hawkins JA (2012) Combined phylogenetic analyses reveal interfamilial relationships and patterns of floral evolution in the eudicot order Fabales. Cladistics 28, 393-421. http://dx.doi.org/10.1111/j.1096-0031.2012.00392.x

Bodas R, Prieto N, García-González R, Andrés S, Giráldez FJ and López S (2012) Manipulation of rumen fermentation and methane production with plant secondary metabolites. Animal Feed Science and Technology 176, 78-93. http://www.sciencedirect.com/science/article/pii/S037784011200243X

Castro-Díaz N, Salaun B, Perret R, Sierro S, Romero JF, Fernández J-A, Rubio-Moraga A and Romero P (2012) Saponins from the Spanish saffron Crocus sativus are efficient adjuvants for protein-based vaccines. Vaccine 30, 388-397. http://www.sciencedirect.com/science/article/pii/S0264410X11017300

Cecílio AB, Faria DBd, Oliveira PdC, Caldas S, Oliveira DAd, Sobral MEG, Duarte MGR, Moreira CPdS, Silva CG and Almeida VLd (2012) Screening of Brazilian medicinal plants for antiviral activity against rotavirus. Journal of Ethnopharmacology 141, 975-981. http://www.sciencedirect.com/science/article/pii/S0378874112001912

Chaudhry AS and Khan MMH (2012) Impacts of different spices on in vitro rumen dry matter disappearance, fermentation and methane of wheat or ryegrass hay based substrates. Livestock Science 146, 84-90. http://www.sciencedirect.com/science/article/pii/S1871141312000339

Chung YH, Zhou M, Holtshausen L, Alexander TW, McAllister TA, Guan LL, Oba M and Beauchemin KA (2012) A fibrolytic enzyme additive for lactating Holstein cow diets: Ruminal fermentation, rumen microbial populations, and enteric methane emissions. Journal of Dairy Science 95, 1419-1427. http://www.sciencedirect.com/science/article/pii/S0022030212000999

Cunha IALd, Zulpo DL, Bogado ALG, de Barros LD, Taroda A, Igarashi M, Navarro IT and Garcia JL (2012) Humoral and cellular immune responses in pigs immunized intranasally with crude rhoptry proteins of Toxoplasma gondii plus Quil-A. Veterinary Parasitology 186, 216-221. http://www.sciencedirect.com/science/article/pii/S0304401711007667

De Geyter E, Swevers L, Caccia S, Geelen D and Smagghe G (2012) Saponins show high entomotoxicity by cell membrane permeation in Lepidoptera. Pest Management Science 68, 1199-1205. http://dx.doi.org/10.1002/ps.3284

De Geyter E, Swevers L, Soin T, Geelen D and Smagghe G (2012) Saponins do not affect the ecdysteroid receptor complex but cause membrane permeation in insect culture cell lines. Journal of Insect Physiology 58, 18-23. http://www.sciencedirect.com/science/article/pii/S0022191011002708

den Brok MH, Nierkens S, Wagenaars JA, Ruers TJ, Schrier CC, Rijke EO and Adema GJ (2012) Saponin-based adjuvants create a highly effective anti-tumor vaccine when combined with in situ tumor destruction. Vaccine 30, 737-744. http://www.sciencedirect.com/science/article/pii/S0264410X11018767

Dendouga N, Fochesato M, Lockman L, Mossman S and Giannini SL (2012) Cell-mediated immune responses to a varicella-zoster virus glycoprotein E vaccine using both a TLR agonist and QS21 in mice. Vaccine 30, 3126-3135. http://www.sciencedirect.com/science/article/pii/S0264410X12001612

Deymeh H, Shadizadeh SR and Motafakkerfard R (2012) Experimental investigation of Seidlitzia rosmarinus effect on oil–water interfacial tension: Usable for chemical enhanced oil recovery. Scientia Iranica 19, 1661-1664. http://www.sciencedirect.com/science/article/pii/S1026309812001459

Donato P, Cacciola F, Tranchida PQ, Dugo P and Mondello L (2012) Mass spectrometry detection in comprehensive liquid chromatography: Basic concepts, instrumental aspects, applications and trends. Mass Spectrometry Reviews 31, 523-559. http://dx.doi.org/10.1002/mas.20353

European Food Safety A (2012) Compendium of botanicals reported to contain naturally occuring substances of possible concern for human health when used in food and food supplements. EFSA Journal 10, n/a-n/a. http://dx.doi.org/10.2903/j.efsa.2012.2663

Fernando GJP, Chen X, Primiero CA, Yukiko SR, Fairmaid EJ, Corbett HJ, Frazer IH, Brown LE and Kendall MAF (2012) Nanopatch targeted delivery of both antigen and adjuvant to skin synergistically drives enhanced antibody responses. Journal of Controlled Release 159, 215-221. http://www.sciencedirect.com/science/article/pii/S0168365912000351

Foged C, Hansen J and Agger EM (2012) License to kill: Formulation requirements for optimal priming of CD8+ CTL responses with particulate vaccine delivery systems. European Journal of Pharmaceutical Sciences 45, 482-491. http://www.sciencedirect.com/science/article/pii/S0928098711002909

Fuentes-Castillo T, Miranda A, Rivera-Hutinel A, Smith-Ramírez C and Holmgren M (2012) Nucleated regeneration of semiarid sclerophyllous forests close to remnant vegetation. Forest Ecology and Management 274, 38-47. http://www.sciencedirect.com/science/article/pii/S0378112712000953

Gad HA, El-Ahmady SH, Abou-Shoer MI and Al-Azizi MM (2012) Application of Chemometrics in Authentication of Herbal Medicines: A Review. Phytochemical Analysis, n/a-n/a. http://dx.doi.org/10.1002/pca.2378

Gianna V, Montes JM, Calandri EL and Guzmán CA (2012) Impact of several variables on the microwave extraction of Chenopodium Quinoa willd saponins. International Journal of Food Science & Technology 47, 1593-1597. http://dx.doi.org/10.1111/j.1365-2621.2012.03008.x

Golemanov K, Tcholakova S, Denkov N, Pelan E and Stoyanov S (2012) Surface shear rheology of saponin adsorption layers. Langmuir 28, 12071-84.

Güroy B, Mantoğlu S, Kayalı S and Şahin İ (2012) Effect of dietary Yucca schidigera extract on growth, total ammonia–nitrogen excretion and haematological parameters of juvenile striped catfish Pangasianodon hypophthalmus. Aquaculture Research, n/a-n/a. http://dx.doi.org/10.1111/are.12001

Hassan SA, Moussa EA and Abbott LC (2012) The effect of methylmercury exposure on early central nervous system development in the zebrafish (Danio rerio) embryo. Journal of Applied Toxicology 32, 707-713. http://dx.doi.org/10.1002/jat.1675

Hussain PR, Dar MA and Wani AM (2012) Effect of edible coating and gamma irradiation on inhibition of mould growth and quality retention of strawberry during refrigerated storage. International Journal of Food Science & Technology 47, 2318-2324. http://dx.doi.org/10.1111/j.1365-2621.2012.03105.x

Joshi MD, Unger WJ, Storm G, van Kooyk Y and Mastrobattista E (2012) Targeting tumor antigens to dendritic cells using particulate carriers. Journal of Controlled Release 161, 25-37. http://www.sciencedirect.com/science/article/pii/S0168365912003380

Kayani MZ, Mukhtar T and Hussain MA (2012) Evaluation of nematicidal effects of Cannabis sativa L. and Zanthoxylum alatum Roxb. against root-knot nematodes, Meloidogyne incognita. Crop Protection 39, 52-56. http://www.sciencedirect.com/science/article/pii/S0261219412000920

Khan H, Saeed M, Gilani AH, Muhammad N, Haq I-u, Ashraf N, Rehman N-u and Haleemi A (2012) Antipyretic and Anticonvulsant Activity of Polygonatum verticillatum: Comparison of Rhizomes and Aerial Parts. Phytotherapy Research, n/a-n/a. http://dx.doi.org/10.1002/ptr.4721

Kushwaha S, Roy S, Maity R, Mallick A, Soni VK, Singh PK, Chaurasiya ND, Sangwan RS, Misra-Bhattacharya S and Mandal C (2012) Chemotypical variations in Withania somnifera lead to differentially modulated immune response in BALB/c mice. Vaccine 30, 1083-1093. http://www.sciencedirect.com/science/article/pii/S0264410X11019542

Lee JS, Awji EG, Lee SJ, Tassew DD, Park YB, Park KS, Kim MK, Kim B and Park SC (2012) Effect of Lactobacillus plantarum CJLP243 on the growth performance and cytokine response of weaning pigs challenged with enterotoxigenic Escherichia coli. J Anim Sci 90, 3709-3717. http://www.journalofanimalscience.org/cgi/content/abstract/90/11/3709

Levitz Stuart M and Golenbock Douglas T (2012) Beyond Empiricism: Informing Vaccine Development through Innate Immunity Research. Cell 148, 1284-1292. http://www.sciencedirect.com/science/article/pii/S0092867412002115

Li W and Powers W (2012) Effects of saponin extracts on air emissions from steers. J Anim Sci 90, 4001-4013. http://www.journalofanimalscience.org/cgi/content/abstract/90/11/4001

Liang Z, Li K, Wang X, Ke Y, Jin Y and Liang X (2012) Combination of off-line two-dimensional hydrophilic interaction liquid chromatography for polar fraction and two-dimensional hydrophilic interaction liquid chromatography&#xa0;×&#xa0;reversed-phase liquid chromatography for medium-polar fraction in a traditional Chinese medicine. Journal of Chromatography A 1224, 61-69. http://www.sciencedirect.com/science/article/pii/S0021967311018309

Liang Z, Li K, Wang X, Ke Y, Jin Y and Liang X (2012) Combination of off-line two-dimensional hydrophilic interaction liquid chromatography for polar fraction and two-dimensional hydrophilic interaction liquid chromatography × reversed-phase liquid chromatography for medium-polar fraction in a traditional Chinese medicine. Journal of Chromatography A 1224, 61-69. http://www.sciencedirect.com/science/article/pii/S0021967311018309

Mazvimba MT, Yu Y, Cui Z-Q and Zhang Y (2012) Optimization and orthogonal design of an ultrasonic-assisted aqueous extraction process for extracting chlorogenic acid from dry tobacco leaves. Chinese Journal of Natural Medicines 10, 311-320. http://www.sciencedirect.com/science/article/pii/S1875536412600648

Msagati TAM (2012) Antifoaming Agents. In Chemistry of Food Additives and Preservatives. (Ed.^(Eds  pp. 167-171. (Blackwell Publishing Ltd.). http://dx.doi.org/10.1002/9781118274132.ch11

Nahuelhual L, Carmona A, Lara A, Echeverría C and González ME (2012) Land-cover change to forest plantations: Proximate causes and implications for the landscape in south-central Chile. Landscape and Urban Planning 107, 12-20. http://www.sciencedirect.com/science/article/pii/S0169204612001302

Naseri V, Hozhabri F and Kafilzadeh F (2012) Assessment of in vitro digestibility and fermentation parameters of alfalfa hay-based diet following direct incorporation of fenugreek seed (Trigonella foenum) and asparagus root (Asparagus officinalis). Journal of Animal Physiology and Animal Nutrition, no-no. http://dx.doi.org/10.1111/j.1439-0396.2012.01318.x

Nasri S and Ben Salem H (2012) Effect of oral administration of Agave americana or Quillaja saponaria extracts on digestion and growth of Barbarine female lamb. Livestock Science 147, 59-65. http://www.sciencedirect.com/science/article/pii/S1871141312001321

Nasri S, Luciano G, Vasta V, Aouadi D, Priolo A, Makkar H and Ben Salem H (2012) Effect of Quillaja saponaria dietary administration on colour, oxidative stability and volatile profile of muscle longissimus dorsi of Barbarine lamb. Meat Sci 92, 582-6.

Nasri S, Luciano G, Vasta V, Aouadi D, Priolo A, Makkar HPS and Ben Salem H (2012) Effect of Quillaja saponaria dietary administration on colour, oxidative stability and volatile profile of muscle longissimus dorsi of Barbarine lamb. Meat Science 92, 582-586. http://www.sciencedirect.com/science/article/pii/S0309174012002124

Nico D, Borges RM, Brandăo LM, Feijó DF, Gomes DC, Palatnik M, Rodrigues MM, da Silva AJR and Palatnik-de-Sousa CB (2012) The adjuvanticity of Chiococca alba saponins increases with the length and hydrophilicity of their sugar chains. Vaccine 30, 3169-3179. http://www.sciencedirect.com/science/article/pii/S0264410X12003532

Oliveira-Nascimento L, Caricati ATP, Abdulack-Lopes F, Neves LCM, Caricati CP, Penna TCV and Stephano MA (2012) Bacillus atrophaeus inactivated spores as a potential adjuvant for veterinary rabies vaccine. Vaccine 30, 3351-3354. http://www.sciencedirect.com/science/article/pii/S0264410X12003921

Owens J, Provenza FD, Wiedmeier RD and Villalba JJ (2012) Influence of saponins and tannins on intake and nutrient digestion of alkaloid-containing foods. Journal of the Science of Food and Agriculture 92, 2373-2378. http://dx.doi.org/10.1002/jsfa.5643

Pan L, Lezama-Davila CM, Isaac-Marquez AP, Calomeni EP, Fuchs JR, Satoskar AR and Kinghorn AD (2012) Sterols with antileishmanial activity isolated from the roots of Pentalinon andrieuxii. Phytochemistry 82, 128-135. http://www.sciencedirect.com/science/article/pii/S0031942212002890

Patra AK, Stiverson J and Yu Z (2012) Effects of quillaja and yucca saponins on communities and select populations of rumen bacteria and archaea, and fermentation in vitro. Journal of Applied Microbiology 113, 1329-1340. http://dx.doi.org/10.1111/j.1365-2672.2012.05440.x

Pedersen Jan S, Oliveira Cristiano LP, Hübschmann Henriette B, Arleth L, Manniche S, Kirkby N and Nielsen Hanne M (2012) Structure of Immune Stimulating Complex Matrices and Immune Stimulating Complexes in Suspension Determined by Small-Angle X-Ray Scattering. Biophysical Journal 102, 2372-2380. http://www.sciencedirect.com/science/article/pii/S0006349512004134

Peixoto MPG, Kaiser S, Verza SG, de Resende PE, Treter J, Pavei C, Borré GL and Ortega GG (2012) LC-UV Assay Method and UPLC/Q-TOF-MS Characterisation of Saponins from Ilex Paraguariensis A. St. Hil. (Mate) Unripe Fruits. Phytochemical Analysis 23, 415-420. http://dx.doi.org/10.1002/pca.1374

Pelosi A, Shepherd R and Walmsley AM (2012) Delivery of plant-made vaccines and therapeutics. Biotechnology Advances 30, 440-448. http://www.sciencedirect.com/science/article/pii/S0734975011001285

Plumptre CD, Ogunniyi AD and Paton JC (2012) Polyhistidine triad proteins of pathogenic streptococci. Trends in Microbiology 20, 485-493. http://www.sciencedirect.com/science/article/pii/S0966842X1200114X

Pumarińo L, Alomar O and Lundgren JG (2012) Effects of floral and extrafloral resource diversity on the fitness of an omnivorous bug, Orius insidiosus. Entomologia Experimentalis et Applicata 145, 181-190. http://dx.doi.org/10.1111/eea.12002

Ramya R and Sangaranarayanan MV (2012) Polypyrrole microfibres synthesized with Quillaja Saponin for sensing of catechol. Sensors and Actuators B: Chemical 173, 40-51. http://www.sciencedirect.com/science/article/pii/S0925400512004960

Rattanapak T, Young K, Rades T and Hook S (2012) Comparative study of liposomes, transfersomes, ethosomes and cubosomes for transcutaneous immunisation: characterisation and in vitro skin penetration. Journal of Pharmacy and Pharmacology 64, 1560-1569. http://dx.doi.org/10.1111/j.2042-7158.2012.01535.x

Rocha T, de Brum Vieira P, Gnoatto S, Tasca T and Gosmann G (2012) Anti-Trichomonas vaginalis activity of saponins from Quillaja, Passiflora, and Ilex species. Parasitol Res 110, 2551-6.

Rocha TD, de Brum Vieira P, Gnoatto SCB, Tasca T and Gosmann G (2012) Anti-Trichomonas vaginalis activity of saponins from Quillaja, Passiflora, and Ilex species. Parasitology research. 110, 2551-2556. http://dx.doi.org/10.1007/s00436-011-2798-1

Rodríguez R and Fondevila M (2012) Effect of saponins from Enterolobium cyclocarpum on in vitro microbial fermentation of the tropical grass Pennisetum purpureum. Journal of Animal Physiology and Animal Nutrition 96, 762-769. http://dx.doi.org/10.1111/j.1439-0396.2011.01161.x

Rojo-Vázquez FA, Meana A, Valcárcel F and Martínez-Valladares M (2012) Update on trematode infections in sheep. Veterinary Parasitology 189, 15-38. http://www.sciencedirect.com/science/article/pii/S0304401712001537

Salem AZM, Hassan AA, Khalil MS, Gado HM, Alsersy H and Simbaya J (2012) Effects of sun-drying and exogenous enzymes on nutrients intake, digestibility and nitrogen utilization in sheep fed Atriplex halimus foliages. Animal Feed Science and Technology 171, 128-135. http://www.sciencedirect.com/science/article/pii/S037784011100441X

Schiappacasse I, Nahuelhual L, Vásquez F and Echeverría C (2012) Assessing the benefits and costs of dryland forest restoration in central Chile. Journal of Environmental Management 97, 38-45. http://www.sciencedirect.com/science/article/pii/S0301479711004178

Schmatz R, Perreira LB, Stefanello N, Mazzanti C, Spanevello R, Gutierres J, Bagatini M, Martins CC, Abdalla FH, Daci da Silva Serres J, Zanini D, Vieira JM, Cardoso AM, Schetinger MR and Morsch VM (2012) Effects of resveratrol on biomarkers of oxidative stress and on the activity of delta aminolevulinic acid dehydratase in liver and kidney of streptozotocin-induced diabetic rats. Biochimie 94, 374-383. http://www.sciencedirect.com/science/article/pii/S0300908411003105

Serrano AE (2012) Effects of Quillaja saponins on growth, feed efficiency, digestive enzyme activities and metabolism of common carp (Cyprinus carpio L). Aquaculture Nutrition, n/a-n/a. http://dx.doi.org/10.1111/j.1365-2095.2012.00980.x

Stadtlander T, Levavi-Sivan B, Kerem Z, Dweik H, Qutob M, Abu-Lafi S, Francis G, Focken U and Becker K (2012) Effects of a saponin fraction extracted from Trigonella foenum-graecum L. and two commercially available saponins on sex ratio and gonad histology of Nile tilapa fry, Oreochromis niloticus (L.). Journal of Applied Ichthyology, n/a-n/a. http://dx.doi.org/10.1111/jai.12002

Stills HF (2012) Chapter 11 - Polyclonal Antibody Production. In The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents. (Ed.^(Eds Mark AS, Karla AS, Ronald P. WilsonA2 - Mark A. Suckow KAS and Ronald PW) pp. 259-274. (Academic Press: Boston). http://www.sciencedirect.com/science/article/pii/B9780123809209000110

Suescun F, Paulino L, Zagal E, Ovalle C and Muńoz C (2012) Plant extracts from the Mediterranean zone of Chile potentially affect soil microbial activity related to N transformations: A laboratory experiment. Acta agriculturć Scandinavica. 62, 556-564. http://dx.doi.org/10.1080/09064710.2012.676668

Talibi I, Askarne L, Boubaker H, Boudyach EH, Msanda F, Saadi B and Ait Ben Aoumar A (2012) Antifungal activity of some Moroccan plants against Geotrichum candidum, the causal agent of postharvest citrus sour rot. Crop Protection 35, 41-46. http://www.sciencedirect.com/science/article/pii/S0261219411004078

Turner TD, Karlsson L, Mapiye C, Rolland DC, Martinsson K and Dugan MER (2012) Dietary influence on the m. longissimus dorsi fatty acid composition of lambs in relation to protein source. Meat Science 91, 472-477. http://www.sciencedirect.com/science/article/pii/S0309174012000794

Verza S, de Resende P, Kaiser S, Quirici L, Teixeira H, Gosmann G, Ferreira F and Ortega G (2012) Micellar aggregates of saponins from Chenopodium quinoa: characterization by dynamic light scattering and transmission electron microscopy. Pharmazie 67, 288-92.

Watson DS, Endsley AN and Huang L (2012) Design considerations for liposomal vaccines: Influence of formulation parameters on antibody and cell-mediated immune responses to liposome associated antigens. Vaccine 30, 2256-2272. http://www.sciencedirect.com/science/article/pii/S0264410X12001089

Wilby KJ, Lau TT, Gilchrist SE and Ensom MH (2012) Mosquirix (RTS,S): A Novel Vaccine for the Prevention of Plasmodium Falciparum Malaria. Annals of Pharmacotherapy 46, 384-393. http://aop.sagepub.com/cgi/content/abstract/46/3/384

Yang Q, Shi X, Gu Q, Zhao S, Shan Y and Xu G (2012) On-line two dimensional liquid chromatography/mass spectrometry for the analysis of triacylglycerides in peanut oil and mouse tissue. Journal of Chromatography B 895–896, 48-55. http://www.sciencedirect.com/science/article/pii/S1570023212001626

Yusuf RO, Noor ZZ, Abba AH, Hassan MAA and Din MFM (2012) Methane emission by sectors: A comprehensive review of emission sources and mitigation methods. Renewable and Sustainable Energy Reviews 16, 5059-5070. http://www.sciencedirect.com/science/article/pii/S1364032112002663

Zbrun MV, Zielinski GC, Piscitelli HC, Descarga C, Urbani LA, Defain Tesoriero MV and Hermida L (2012) Evaluation of anti-Moraxella bovis pili immunoglobulin-A in tears following intranasal vaccination of cattle. Research in Veterinary Science 93, 183-189. http://www.sciencedirect.com/science/article/pii/S0034528811001822

Zhang J, Cao W, Tian J, Yue R, Li L, Guo B, Shan L, Yu B and Zhang W (2012) Evaluation of novel saponins from Psammosilene tunicoides and their analogs as immunomodulators. International Immunopharmacology 14, 21-26. http://www.sciencedirect.com/science/article/pii/S1567576912001750

Zulpo DL, Headley SA, Biazzono L, da Cunha IAL, Igarashi M, de Barros LD, Taroda A, Cardim ST, Bogado ALG, Navarro IT and Garcia JL (2012) Oocyst shedding in cats vaccinated by the nasal and rectal routes with crude rhoptry proteins of Toxoplasma gondii. Experimental Parasitology 131, 223-230. http://www.sciencedirect.com/science/article/pii/S0014489412001245

Zúńiga GE, Junqueira-Gonçalves MP, Pizarro M, Contreras R, Tapia A and Silva S (2012) Effect of ionizing energy on extracts of Quillaja saponaria to be used as an antimicrobial agent on irradiated edible coating for fresh strawberries. Radiation Physics and Chemistry 81, 64-69. http://www.sciencedirect.com/science/article/pii/S0969806X11002829

 

 

References 1901-2013 (and links to abstracts):
[Number of papers mentioning Quillaja saponaria: 994; Any undated papers have been included at the end]

 

Chlibek R, Bayas JM, Collins H, de la Pinta MLR, Ledent E, Mols JF and Heineman TC (2013) Safety and Immunogenicity of an AS01-adjuvanted Varicella-zoster Virus Subunit Candidate Vaccine Against Herpes Zoster in Adults >=50 Years of Age. The Journal of Infectious Disease, jit365. http://jid.oxfordjournals.org//cgi/content/abstract/jit365v2

HASSAN SB, GULLBO J, HU K, BERENJIAN S, MOREIN B and NYGREN P (2013) The Nanoparticulate Quillaja Saponin BBE Is Selectively Active Towards Renal Cell Carcinoma. Anticancer Res 33, 143-51. http://ar.iiarjournals.org/cgi/content/abstract/33/1/143

Morgavi DP, Martin C and Boudra H (2013) Fungal secondary metabolites from Monascus spp. reduce rumen methane production in vitro and in vivo. J Anim Sci 91, 848-60. http://www.journalofanimalscience.org/cgi/content/abstract/91/2/848

Perry CGR, Kane DA, Lanza IR and Neufer PD (2013) Methods for Assessing Mitochondrial Function in Diabetes. Diabetes 62, 1041-53. http://diabetes.diabetesjournals.org/cgi/content/abstract/62/4/1041

Scheurer W, Spring P and Maertens L (2013) Effect of 3 dietary phytogenic products on production performance and coccidiosis in challenged broiler chickens. J. Appl. Poult. Res. 22, 591-9. http://japr.fass.org/cgi/content/abstract/22/3/591

Ahlberg V, Lövgren Bengtsson K, Wallgren P and Fossum C (2012) Global transcriptional response to ISCOM-Matrix adjuvant at the site of administration and in the draining lymph node early after intramuscular injection in pigs. Developmental &amp; Comparative Immunology 38, 17-26. http://www.sciencedirect.com/science/article/pii/S0145305X12000432

Ahmed FK, Clark BE, Burton DR and Pantophlet R (2012) An engineered mutant of HIV-1 gp120 formulated with adjuvant Quil A promotes elicitation of antibody responses overlapping the CD4-binding site. Vaccine 30, 922-30. http://www.sciencedirect.com/science/article/pii/S0264410X11018858

ALI R, MIRZA Z, ASHRAF GMD, KAMAL MA, ANSARI SA, DAMANHOURI GA, ABUZENADAH AM, CHAUDHARY AG and SHEIKH IA (2012) New Anticancer Agents: Recent Developments in Tumor Therapy. Anticancer Res 32, 2999-3005. http://ar.iiarjournals.org/cgi/content/abstract/32/7/2999

Arabski M, Wegierek-Ciuk A, Czerwonka G, Lankoff A and Kaca W (2012) Effects of saponins against clinical E. coli strains and eukaryotic cell line. J Biomed Biotechnol 2012, 286216.

Augustin JM, Drok S, Shinoda T, Sanmiya K, Nielsen JK, Khakimov B, Olsen CE, Hansen EH, Kuzina V, Ekstrom CT, Hauser T and Bak S (2012) UDP-Glycosyltransferases from the UGT73C Subfamily in Barbarea vulgaris Catalyze Sapogenin 3-O-Glucosylation in Saponin-Mediated Insect Resistance. Plant Physiology 160, 1881-95. http://www.plantphysiol.org/cgi/content/abstract/160/4/1881

Barhate G, Gautam M, Gairola S, Jadhav S and Pokharkar V (2012) Quillaja saponaria extract as mucosal adjuvant with chitosan functionalized gold nanoparticles for mucosal vaccine delivery: Stability and immunoefficiency studies. Int J Pharm.

Baz Morelli A, Becher D, Koernig S, Silva A, Drane D and Maraskovsky E (2012) ISCOMATRIX: a novel adjuvant for use in prophylactic and therapeutic vaccines against infectious diseases. J. Med. Microbiol. 61, 935-43. http://jmm.sgmjournals.org/cgi/content/abstract/61/Pt_7/935

Becerra PI and Montenegro G (2012) The widely invasive tree Pinus radiata facilitates regeneration of native woody species in a semi-arid ecosystem. Applied Vegetation Science, n/a-n/a. http://dx.doi.org/10.1111/j.1654-109X.2012.01221.x

Bello MA, Rudall PJ and Hawkins JA (2012) Combined phylogenetic analyses reveal interfamilial relationships and patterns of floral evolution in the eudicot order Fabales. Cladistics 28, 393-421. http://dx.doi.org/10.1111/j.1096-0031.2012.00392.x

Carlson D, Fernandez JA, Poulsen HD, Nielsen B and Jacobsen SE (2012) Effects of quinoa hull meal on piglet performance and intestinal epithelial physiology. Journal of Animal Physiology and Animal Nutrition 96, 198-205. http://dx.doi.org/10.1111/j.1439-0396.2011.01138.x

Castro-Díaz N, Salaun B, Perret R, Sierro S, Romero JF, Fernández J-A, Rubio-Moraga A and Romero P (2012) Saponins from the Spanish saffron Crocus sativus are efficient adjuvants for protein-based vaccines. Vaccine 30, 388-97. http://www.sciencedirect.com/science/article/pii/S0264410X11017300

Cecílio AB, Faria DBd, Oliveira PdC, Caldas S, Oliveira DAd, Sobral MEG, Duarte MGR, Moreira CPdS, Silva CG and Almeida VLd (2012) Screening of Brazilian medicinal plants for antiviral activity against rotavirus. Journal of Ethnopharmacology 141, 975-81. http://www.sciencedirect.com/science/article/pii/S0378874112001912

Chaudhry AS and Khan MMH (2012) Impacts of different spices on in vitro rumen dry matter disappearance, fermentation and methane of wheat or ryegrass hay based substrates. Livestock Science 146, 84-90. http://www.sciencedirect.com/science/article/pii/S1871141312000339

Chung YH, Zhou M, Holtshausen L, Alexander TW, McAllister TA, Guan LL, Oba M and Beauchemin KA (2012) A fibrolytic enzyme additive for lactating Holstein cow diets: Ruminal fermentation, rumen microbial populations, and enteric methane emissions. Journal of Dairy Science 95, 1419-27. http://www.sciencedirect.com/science/article/pii/S0022030212000999

Cunha IALd, Zulpo DL, Bogado ALG, de Barros LD, Taroda A, Igarashi M, Navarro IT and Garcia JL (2012) Humoral and cellular immune responses in pigs immunized intranasally with crude rhoptry proteins of Toxoplasma gondii plus Quil-A. Veterinary Parasitology 186, 216-21. http://www.sciencedirect.com/science/article/pii/S0304401711007667

Das BK, Pradhan J, Sahu S, Marhual NP, Mishra BK and Eknath AE (2012) Microcystis aeruginosa (Kütz) incorporated diets increase immunity and survival of Indian major carp Labeo rohita (Ham.) against Aeromonas hydrophila infection. Aquaculture Research, n/a-n/a. http://dx.doi.org/10.1111/j.1365-2109.2012.03098.x

De Geyter E, Smagghe G, Rahbé Y and Geelen D (2012) Triterpene saponins of Quillaja saponaria show strong aphicidal and deterrent activity against the pea aphid Acyrthosiphon pisum. Pest Management Science 68, 164-9. http://dx.doi.org/10.1002/ps.2235

De Geyter E, Swevers L, Caccia S, Geelen D and Smagghe G (2012) Saponins show high entomotoxicity by cell membrane permeation in Lepidoptera. Pest Management Science 68, 1199-205. http://dx.doi.org/10.1002/ps.3284

De Geyter E, Swevers L, Soin T, Geelen D and Smagghe G (2012) Saponins do not affect the ecdysteroid receptor complex but cause membrane permeation in insect culture cell lines. Journal of Insect Physiology 58, 18-23. http://www.sciencedirect.com/science/article/pii/S0022191011002708

den Brok MH, Nierkens S, Wagenaars JA, Ruers TJ, Schrier CC, Rijke EO and Adema GJ (2012) Saponin-based adjuvants create a highly effective anti-tumor vaccine when combined with in situ tumor destruction. Vaccine 30, 737-44. http://www.sciencedirect.com/science/article/pii/S0264410X11018767

Dendouga N, Fochesato M, Lockman L, Mossman S and Giannini SL (2012) Cell-mediated immune responses to a varicella-zoster virus glycoprotein E vaccine using both a TLR agonist and QS21 in mice. Vaccine 30, 3126-35. http://www.sciencedirect.com/science/article/pii/S0264410X12001612

Deng JM, Mai KS, Ai QH, Zhang WB, Wang XJ, Xu W, Liufu ZG, Cai YH and Chen W (2012) Effects of antinutritional factors on plasma lipoprotein levels in Japanese flounder Paralichthys olivaceus. Journal of Fish Biology 80, 286-300. http://dx.doi.org/10.1111/j.1095-8649.2011.03170.x

Donato P, Cacciola F, Tranchida PQ, Dugo P and Mondello L (2012) Mass spectrometry detection in comprehensive liquid chromatography: Basic concepts, instrumental aspects, applications and trends. Mass Spectrometry Reviews 31, 523-59. http://dx.doi.org/10.1002/mas.20353

Fernando GJP, Chen X, Primiero CA, Yukiko SR, Fairmaid EJ, Corbett HJ, Frazer IH, Brown LE and Kendall MAF (2012) Nanopatch targeted delivery of both antigen and adjuvant to skin synergistically drives enhanced antibody responses. Journal of Controlled Release 159, 215-21. http://www.sciencedirect.com/science/article/pii/S0168365912000351

Foged C, Hansen J and Agger EM (2012) License to kill: Formulation requirements for optimal priming of CD8+ CTL responses with particulate vaccine delivery systems. European Journal of Pharmaceutical Sciences 45, 482-91. http://www.sciencedirect.com/science/article/pii/S0928098711002909

Fuentes-Castillo T, Miranda A, Rivera-Hutinel A, Smith-Ramírez C and Holmgren M (2012) Nucleated regeneration of semiarid sclerophyllous forests close to remnant vegetation. Forest Ecology and Management 274, 38-47. http://www.sciencedirect.com/science/article/pii/S0378112712000953

Gad HA, El-Ahmady SH, Abou-Shoer MI and Al-Azizi MM (2012) Application of Chemometrics in Authentication of Herbal Medicines: A Review. Phytochemical Analysis, n/a-n/a. http://dx.doi.org/10.1002/pca.2378

Gianna V, Montes JM, Calandri EL and Guzmán CA (2012) Impact of several variables on the microwave extraction of Chenopodium Quinoa willd saponins. International Journal of Food Science & Technology 47, 1593-7. http://dx.doi.org/10.1111/j.1365-2621.2012.03008.x

Golemanov K, Tcholakova S, Denkov N, Pelan E and Stoyanov S (2012) Surface shear rheology of saponin adsorption layers. Langmuir 28, 12071-84.

Güroy B, Mantoğlu S, Kayalı S and Şahin İ (2012) Effect of dietary Yucca schidigera extract on growth, total ammonia–nitrogen excretion and haematological parameters of juvenile striped catfish Pangasianodon hypophthalmus. Aquaculture Research, n/a-n/a. http://dx.doi.org/10.1111/are.12001

Harvey DJ (2012) Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: An update for 2007–2008. Mass Spectrometry Reviews 31, 183-311. http://dx.doi.org/10.1002/mas.20333

Hassan SA, Moussa EA and Abbott LC (2012) The effect of methylmercury exposure on early central nervous system development in the zebrafish (Danio rerio) embryo. Journal of Applied Toxicology 32, 707-13. http://dx.doi.org/10.1002/jat.1675

Hedayat M, Takeda K and Rezaei N (2012) Prophylactic and therapeutic implications of toll-like receptor ligands. Medicinal Research Reviews 32, 294-325. http://dx.doi.org/10.1002/med.20214

Hussain PR, Dar MA and Wani AM (2012) Effect of edible coating and gamma irradiation on inhibition of mould growth and quality retention of strawberry during refrigerated storage. International Journal of Food Science & Technology 47, 2318-24. http://dx.doi.org/10.1111/j.1365-2621.2012.03105.x

Joshi MD, Unger WJ, Storm G, van Kooyk Y and Mastrobattista E (2012) Targeting tumor antigens to dendritic cells using particulate carriers. Journal of Controlled Release 161, 25-37. http://www.sciencedirect.com/science/article/pii/S0168365912003380

Kayani MZ, Mukhtar T and Hussain MA (2012) Evaluation of nematicidal effects of Cannabis sativa L. and Zanthoxylum alatum Roxb. against root-knot nematodes, Meloidogyne incognita. Crop Protection 39, 52-6. http://www.sciencedirect.com/science/article/pii/S0261219412000920

Khan H, Saeed M, Gilani AH, Muhammad N, Haq I-u, Ashraf N, Rehman N-u and Haleemi A (2012) Antipyretic and Anticonvulsant Activity of Polygonatum verticillatum: Comparison of Rhizomes and Aerial Parts. Phytotherapy Research, n/a-n/a. http://dx.doi.org/10.1002/ptr.4721

Khursheed S, Anwer R, Zutshi S and Fatma T (2012) SCREENING OF PHOTOSYNTHETIC O2-EVOLVING PROKARYOTES FOR AN INSULIN-LIKE ANTIGEN1. Journal of Phycology 48, 243-5. http://dx.doi.org/10.1111/j.1529-8817.2011.01086.x

Kushwaha S, Roy S, Maity R, Mallick A, Soni VK, Singh PK, Chaurasiya ND, Sangwan RS, Misra-Bhattacharya S and Mandal C (2012) Chemotypical variations in Withania somnifera lead to differentially modulated immune response in BALB/c mice. Vaccine 30, 1083-93. http://www.sciencedirect.com/science/article/pii/S0264410X11019542

Lee JS, Awji EG, Lee SJ, Tassew DD, Park YB, Park KS, Kim MK, Kim B and Park SC (2012) Effect of Lactobacillus plantarum CJLP243 on the growth performance and cytokine response of weaning pigs challenged with enterotoxigenic Escherichia coli. J Anim Sci 90, 3709-17. http://www.journalofanimalscience.org/cgi/content/abstract/90/11/3709

Levitz Stuart M and Golenbock Douglas T (2012) Beyond Empiricism: Informing Vaccine Development through Innate Immunity Research. Cell 148, 1284-92. http://www.sciencedirect.com/science/article/pii/S0092867412002115

Li W and Powers W (2012) Effects of saponin extracts on air emissions from steers. J Anim Sci 90, 4001-13. http://www.journalofanimalscience.org/cgi/content/abstract/90/11/4001

Liang Z, Li K, Wang X, Ke Y, Jin Y and Liang X (2012) Combination of off-line two-dimensional hydrophilic interaction liquid chromatography for polar fraction and two-dimensional hydrophilic interaction liquid chromatography&#xa0;×&#xa0;reversed-phase liquid chromatography for medium-polar fraction in a traditional Chinese medicine. Journal of Chromatography A 1224, 61-9. http://www.sciencedirect.com/science/article/pii/S0021967311018309

Mazvimba MT, Yu Y, Cui Z-Q and Zhang Y (2012) Optimization and orthogonal design of an ultrasonic-assisted aqueous extraction process for extracting chlorogenic acid from dry tobacco leaves. Chinese Journal of Natural Medicines 10, 311-20. http://www.sciencedirect.com/science/article/pii/S1875536412600648

Msagati TAM (2012) Antifoaming Agents. In ‘Chemistry of Food Additives and Preservatives’. (Ed.^(Eds  pp. 167-71. (Blackwell Publishing Ltd.). http://dx.doi.org/10.1002/9781118274132.ch11

Nahuelhual L, Carmona A, Lara A, Echeverría C and González ME (2012) Land-cover change to forest plantations: Proximate causes and implications for the landscape in south-central Chile. Landscape and Urban Planning 107, 12-20. http://www.sciencedirect.com/science/article/pii/S0169204612001302

Naseri V, Hozhabri F and Kafilzadeh F (2012) Assessment of in vitro digestibility and fermentation parameters of alfalfa hay-based diet following direct incorporation of fenugreek seed (Trigonella foenum) and asparagus root (Asparagus officinalis). Journal of Animal Physiology and Animal Nutrition, no-no. http://dx.doi.org/10.1111/j.1439-0396.2012.01318.x

Nasri S and Ben Salem H (2012) Effect of oral administration of Agave americana or Quillaja saponaria extracts on digestion and growth of Barbarine female lamb. Livestock Science 147, 59-65. http://www.sciencedirect.com/science/article/pii/S1871141312001321

Nasri S, Luciano G, Vasta V, Aouadi D, Priolo A, Makkar H and Ben Salem H (2012) Effect of Quillaja saponaria dietary administration on colour, oxidative stability and volatile profile of muscle longissimus dorsi of Barbarine lamb. Meat Sci 92, 582-6.

Nico D, Borges RM, Brandăo LM, Feijó DF, Gomes DC, Palatnik M, Rodrigues MM, da Silva AJR and Palatnik-de-Sousa CB (2012) The adjuvanticity of Chiococca alba saponins increases with the length and hydrophilicity of their sugar chains. Vaccine 30, 3169-79. http://www.sciencedirect.com/science/article/pii/S0264410X12003532

Oliveira-Nascimento L, Caricati ATP, Abdulack-Lopes F, Neves LCM, Caricati CP, Penna TCV and Stephano MA (2012) Bacillus atrophaeus inactivated spores as a potential adjuvant for veterinary rabies vaccine. Vaccine 30, 3351-4. http://www.sciencedirect.com/science/article/pii/S0264410X12003921

Owens J, Provenza FD, Wiedmeier RD and Villalba JJ (2012) Influence of saponins and tannins on intake and nutrient digestion of alkaloid-containing foods. Journal of the Science of Food and Agriculture 92, 2373-8. http://dx.doi.org/10.1002/jsfa.5643

Patra AK, Stiverson J and Yu Z (2012) Effects of quillaja and yucca saponins on communities and select populations of rumen bacteria and archaea, and fermentation in vitro. Journal of Applied Microbiology 113, 1329-40. http://dx.doi.org/10.1111/j.1365-2672.2012.05440.x

Pedersen Jan S, Oliveira Cristiano LP, Hübschmann Henriette B, Arleth L, Manniche S, Kirkby N and Nielsen Hanne M (2012) Structure of Immune Stimulating Complex Matrices and Immune Stimulating Complexes in Suspension Determined by Small-Angle X-Ray Scattering. Biophysical Journal 102, 2372-80. http://www.sciencedirect.com/science/article/pii/S0006349512004134

Peixoto MPG, Kaiser S, Verza SG, de Resende PE, Treter J, Pavei C, Borré GL and Ortega GG (2012) LC-UV Assay Method and UPLC/Q-TOF-MS Characterisation of Saponins from Ilex Paraguariensis A. St. Hil. (Mate) Unripe Fruits. Phytochemical Analysis 23, 415-20. http://dx.doi.org/10.1002/pca.1374

Pelosi A, Shepherd R and Walmsley AM (2012) Delivery of plant-made vaccines and therapeutics. Biotechnology Advances 30, 440-8. http://www.sciencedirect.com/science/article/pii/S0734975011001285

Pumarińo L, Alomar O and Lundgren JG (2012) Effects of floral and extrafloral resource diversity on the fitness of an omnivorous bug, Orius insidiosus. Entomologia Experimentalis et Applicata 145, 181-90. http://dx.doi.org/10.1111/eea.12002

Quispe-Fuentes I, Vega-GÁLvez A, Miranda M, Lemus-Mondaca R, Lozano M and Ah-Hen K (2012) A KINETIC APPROACH TO SAPONIN EXTRACTION DURING WASHING OF QUINOA (CHENOPODIUM QUINOA WILLD.) SEEDS. Journal of Food Process Engineering, no-no. http://dx.doi.org/10.1111/j.1745-4530.2012.00673.x

Rattanapak T, Young K, Rades T and Hook S (2012) Comparative study of liposomes, transfersomes, ethosomes and cubosomes for transcutaneous immunisation: characterisation and in vitro skin penetration. Journal of Pharmacy and Pharmacology 64, 1560-9. http://dx.doi.org/10.1111/j.2042-7158.2012.01535.x

Rocha T, de Brum Vieira P, Gnoatto S, Tasca T and Gosmann G (2012) Anti-Trichomonas vaginalis activity of saponins from Quillaja, Passiflora, and Ilex species. Parasitol Res 110, 2551-6.

Rodríguez R and Fondevila M (2012) Effect of saponins from Enterolobium cyclocarpum on in vitro microbial fermentation of the tropical grass Pennisetum purpureum. Journal of Animal Physiology and Animal Nutrition 96, 762-9. http://dx.doi.org/10.1111/j.1439-0396.2011.01161.x

Salem AZM, Hassan AA, Khalil MS, Gado HM, Alsersy H and Simbaya J (2012) Effects of sun-drying and exogenous enzymes on nutrients intake, digestibility and nitrogen utilization in sheep fed Atriplex halimus foliages. Animal Feed Science and Technology 171, 128-35. http://www.sciencedirect.com/science/article/pii/S037784011100441X

Schiappacasse I, Nahuelhual L, Vásquez F and Echeverría C (2012) Assessing the benefits and costs of dryland forest restoration in central Chile. Journal of Environmental Management 97, 38-45. http://www.sciencedirect.com/science/article/pii/S0301479711004178

Schmatz R, Perreira LB, Stefanello N, Mazzanti C, Spanevello R, Gutierres J, Bagatini M, Martins CC, Abdalla FH, Daci da Silva Serres J, Zanini D, Vieira JM, Cardoso AM, Schetinger MR and Morsch VM (2012) Effects of resveratrol on biomarkers of oxidative stress and on the activity of delta aminolevulinic acid dehydratase in liver and kidney of streptozotocin-induced diabetic rats. Biochimie 94, 374-83. http://www.sciencedirect.com/science/article/pii/S0300908411003105

Serrano AE (2012) Effects of Quillaja saponins on growth, feed efficiency, digestive enzyme activities and metabolism of common carp (Cyprinus carpio L). Aquaculture Nutrition, n/a-n/a. http://dx.doi.org/10.1111/j.1365-2095.2012.00980.x

Stadtlander T, Levavi-Sivan B, Kerem Z, Dweik H, Qutob M, Abu-Lafi S, Francis G, Focken U and Becker K (2012) Effects of a saponin fraction extracted from Trigonella foenum-graecum L. and two commercially available saponins on sex ratio and gonad histology of Nile tilapa fry, Oreochromis niloticus (L.). Journal of Applied Ichthyology, n/a-n/a. http://dx.doi.org/10.1111/jai.12002

Stills HF (2012) Chapter 11 - Polyclonal Antibody Production. In ‘The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents’. (Ed.^(Eds Mark AS, Karla AS, Ronald P. WilsonA2 - Mark A. Suckow KAS and Ronald PW) pp. 259-74. (Academic Press: Boston). http://www.sciencedirect.com/science/article/pii/B9780123809209000110

Talibi I, Askarne L, Boubaker H, Boudyach EH, Msanda F, Saadi B and Ait Ben Aoumar A (2012) Antifungal activity of some Moroccan plants against Geotrichum candidum, the causal agent of postharvest citrus sour rot. Crop Protection 35, 41-6. http://www.sciencedirect.com/science/article/pii/S0261219411004078

Turner TD, Karlsson L, Mapiye C, Rolland DC, Martinsson K and Dugan MER (2012) Dietary influence on the m. longissimus dorsi fatty acid composition of lambs in relation to protein source. Meat Science 91, 472-7. http://www.sciencedirect.com/science/article/pii/S0309174012000794

Verza S, de Resende P, Kaiser S, Quirici L, Teixeira H, Gosmann G, Ferreira F and Ortega G (2012) Micellar aggregates of saponins from Chenopodium quinoa: characterization by dynamic light scattering and transmission electron microscopy. Pharmazie 67, 288-92.

Watson DS, Endsley AN and Huang L (2012) Design considerations for liposomal vaccines: Influence of formulation parameters on antibody and cell-mediated immune responses to liposome associated antigens. Vaccine 30, 2256-72. http://www.sciencedirect.com/science/article/pii/S0264410X12001089

Wilby KJ, Lau TT, Gilchrist SE and Ensom MH (2012) Mosquirix (RTS,S): A Novel Vaccine for the Prevention of Plasmodium Falciparum Malaria. Annals of Pharmacotherapy 46, 384-93. http://aop.sagepub.com/cgi/content/abstract/46/3/384

Wulff EG, Zida E, Torp J and Lund OS (2012) Yucca schidigera extract: a potential biofungicide against seedborne pathogens of sorghum. Plant Pathology 61, 331-8. http://dx.doi.org/10.1111/j.1365-3059.2011.02517.x

Yang Q, Shi X, Gu Q, Zhao S, Shan Y and Xu G (2012) On-line two dimensional liquid chromatography/mass spectrometry for the analysis of triacylglycerides in peanut oil and mouse tissue. Journal of Chromatography B 895–896, 48-55. http://www.sciencedirect.com/science/article/pii/S1570023212001626

Yusuf RO, Noor ZZ, Abba AH, Hassan MAA and Din MFM (2012) Methane emission by sectors: A comprehensive review of emission sources and mitigation methods. Renewable and Sustainable Energy Reviews 16, 5059-70. http://www.sciencedirect.com/science/article/pii/S1364032112002663

Zbrun MV, Zielinski GC, Piscitelli HC, Descarga C, Urbani LA, Defain Tesoriero MV and Hermida L (2012) Evaluation of anti-Moraxella bovis pili immunoglobulin-A in tears following intranasal vaccination of cattle. Research in Veterinary Science 93, 183-9. http://www.sciencedirect.com/science/article/pii/S0034528811001822

Zhang J, Cao W, Tian J, Yue R, Li L, Guo B, Shan L, Yu B and Zhang W (2012) Evaluation of novel saponins from Psammosilene tunicoides and their analogs as immunomodulators. International Immunopharmacology 14, 21-6. http://www.sciencedirect.com/science/article/pii/S1567576912001750

Zulpo DL, Headley SA, Biazzono L, da Cunha IAL, Igarashi M, de Barros LD, Taroda A, Cardim ST, Bogado ALG, Navarro IT and Garcia JL (2012) Oocyst shedding in cats vaccinated by the nasal and rectal routes with crude rhoptry proteins of Toxoplasma gondii. Experimental Parasitology 131, 223-30. http://www.sciencedirect.com/science/article/pii/S0014489412001245

Zúńiga GE, Junqueira-Gonçalves MP, Pizarro M, Contreras R, Tapia A and Silva S (2012) Effect of ionizing energy on extracts of Quillaja saponaria to be used as an antimicrobial agent on irradiated edible coating for fresh strawberries. Radiation Physics and Chemistry 81, 64-9. http://www.sciencedirect.com/science/article/pii/S0969806X11002829

Anonymous (2011) Glossary. Perspectives in Vaccinology 1, XI-XXII. http://www.sciencedirect.com/science/article/pii/S2210762211000106

Adăo CR, da Silva BP and Parente JP (2011) A new steroidal saponin with antiinflammatory and antiulcerogenic properties from the bulbs of Allium ampeloprasum var. porrum. Fitoterapia 82, 1175-80. http://www.sciencedirect.com/science/article/pii/S0367326X11001882

Adăo CR, da Silva BP and Parente JP (2011) A new steroidal saponin from Allium ampeloprasum var. porrum with antiinflammatory and gastroprotective effects. Phytochemistry Letters 4, 306-10. http://www.sciencedirect.com/science/article/pii/S1874390011000838

Aguerre MJ, Wattiaux MA, Powell JM, Broderick GA and Arndt C (2011) Effect of forage-to-concentrate ratio in dairy cow diets on emission of methane, carbon dioxide, and ammonia, lactation performance, and manure excretion. Journal of Dairy Science 94, 3081-93. http://www.sciencedirect.com/science/article/pii/S0022030211002955

Alsante KM, Baertschi SW, Coutant M, Marquez BL, Sharp TR and Zelesky TC (2011) 3 - Degradation and Impurity Analysis for Pharmaceutical Drug Candidates. In ‘Separation Science and Technology’. (Ed.^(Eds Satinder A and Stephen S) pp. 59-169. (Academic Press). http://www.sciencedirect.com/science/article/pii/B9780123756800000036

Arrau S, Delporte C, Cartagena C, Rodriguez-Diaz M, Gonzalez P, Silva X, Cassels B and Miranda H (2011) Antinociceptive activity of Quillaja saponaria Mol. saponin extract, quillaic acid and derivatives in mice. J Ethnopharmacol 133, 164-7.

Arrau S, Delporte C, Cartagena C, Rodríguez-Díaz M, González P, Silva X, Cassels BK and Miranda HF (2011) Antinociceptive activity of Quillaja saponaria Mol. saponin extract, quillaic acid and derivatives in mice. Journal of Ethnopharmacology 133, 164-7. http://www.sciencedirect.com/science/article/pii/S0378874110006574

Augustin JM, Kuzina V, Andersen SB and Bak S (2011) Molecular activities, biosynthesis and evolution of triterpenoid saponins. Phytochemistry 72, 435-57. http://www.sciencedirect.com/science/article/pii/S0031942211000410

Avila JS, Chaves AV, Hernandez-Calva M, Beauchemin KA, McGinn SM, Wang Y, Harstad OM and McAllister TA (2011) Effects of replacing barley grain in feedlot diets with increasing levels of glycerol on in vitro fermentation and methane production. Animal Feed Science and Technology 166–167, 265-8. http://www.sciencedirect.com/science/article/pii/S0377840111001350

Axelsen TV, Holm A, Christiansen G and Birkelund S (2011) Identification of the shortest Aβ-peptide generating highly specific antibodies against the C-terminal end of amyloid-β42. Vaccine 29, 3260-9. http://www.sciencedirect.com/science/article/pii/S0264410X11002398

Bankefors J, Broberg S, Nord L and Kenne L (2011) Electrospray ionization ion-trap multiple-stage mass spectrometry of Quillaja saponins. J Mass Spectrom 46, 658-65.

Bankefors J, Broberg S, Nord LI and Kenne L (2011) Electrospray ionization ion-trap multiple-stage mass spectrometry of Quillaja saponins. Journal of Mass Spectrometry 46, 658-65. http://dx.doi.org/10.1002/jms.1935

Becerra PI, González-Rodríguez V, Smith-Ramírez C and Armesto JJ (2011) Spatio-temporal variation in the effect of herbaceous layer on woody seedling survival in a Chilean mediterranean ecosystem. Journal of Vegetation Science 22, 847-55. http://dx.doi.org/10.1111/j.1654-1103.2011.01291.x

Bernal J, Ares AM, Pól J and Wiedmer SK (2011) Hydrophilic interaction liquid chromatography in food analysis. Journal of Chromatography A 1218, 7438-52. http://www.sciencedirect.com/science/article/pii/S0021967311006182

Brogna D, Nasri S, Salem H, Mele M, Serra A, Bella M, Priolo A, Makkar H and Vasta V (2011) Effect of dietary saponins from Quillaja saponaria L. on fatty acid composition and cholesterol content in muscle Longissimus dorsi of lambs. Animal 5, 1124-30.

Chandler D, Bailey AS, Tatchell GM, Davidson G, Greaves J and Grant WP (2011) The development, regulation and use of biopesticides for integrated pest management. Phil Trans R Soc B 366, 1987-98. http://rstb.royalsocietypublishing.org/cgi/content/abstract/366/1573/1987

Chen W, Ai Q, Mai K, Xu W, Liufu Z, Zhang W and Cai Y (2011) Effects of dietary soybean saponins on feed intake, growth performance, digestibility and intestinal structure in juvenile Japanese flounder (Paralichthys olivaceus). Aquaculture 318, 95-100. http://www.sciencedirect.com/science/article/pii/S0044848611003772

Cox RJ, Pedersen G, Madhun AS, Svindland S, Sćvik M, Breakwell L, Hoschler K, Willemsen M, Campitelli L, Nřstbakken JK, Weverling GJ, Klap J, McCullough KC, Zambon M, Kompier R and Sjursen H (2011) Evaluation of a virosomal H5N1 vaccine formulated with Matrix M™ adjuvant in a phase I clinical trial. Vaccine 29, 8049-59. http://www.sciencedirect.com/science/article/pii/S0264410X11012837

Cranage MP, Fraser CA, Cope A, McKay PF, Seaman MS, Cole T, Mahmoud AN, Hall J, Giles E, Voss G, Page M, Almond N and Shattock RJ (2011) Antibody responses after intravaginal immunisation with trimeric HIV-1CN54 clade C gp140 in Carbopol gel are augmented by systemic priming or boosting with an adjuvanted formulation. Vaccine 29, 1421-30. http://www.sciencedirect.com/science/article/pii/S0264410X1001786X

Dagostin S, Schärer H-J, Pertot I and Tamm L (2011) Are there alternatives to copper for controlling grapevine downy mildew in organic viticulture? Crop Protection 30, 776-88. http://www.sciencedirect.com/science/article/pii/S026121941100086X

De Temmerman M-L, Rejman J, Demeester J, Irvine DJ, Gander B and De Smedt SC (2011) Particulate vaccines: on the quest for optimal delivery and immune response. Drug Discovery Today 16, 569-82. http://www.sciencedirect.com/science/article/pii/S1359644611001334

Eliasson DG, Helgeby A, Schön K, Nygren C, El-Bakkouri K, Fiers W, Saelens X, Lövgren KB, Nyström I and Lycke NY (2011) A novel non-toxic combined CTA1-DD and ISCOMS adjuvant vector for effective mucosal immunization against influenza virus. Vaccine 29, 3951-61. http://www.sciencedirect.com/science/article/pii/S0264410X1100483X

Fischer M, Pensec F, Demangeat G, Farine S, Chong J, Ramirez-Suero M, Mazet F and Bertsch C (2011) Impact of Quillaja saponaria saponins on grapevine ecosystem organisms. Antonie Van Leeuwenhoek 100, 197-206.

Freches D, Romano M, Korf H, Renauld J-C, Van Snick J, Uyttenhove C and Huygen K (2011) Increased Pulmonary Tumor Necrosis Factor Alpha, Interleukin-6 (IL-6), and IL-17A Responses Compensate for Decreased Gamma Interferon Production in Anti-IL-12 Autovaccine-Treated, Mycobacterium bovis BCG-Vaccinated Mice. Clin. Vaccine Immunol. 18, 95-104. http://cvi.asm.org/cgi/content/abstract/18/1/95

G. Peixoto MP, Treter J, de Resende PE, da Silveira NP, Ortega GG, Lawrence MJ and Dreiss CA (2011) Wormlike micellar aggregates of saponins from Ilex paraguariensis A. St. Hil. (mate): A characterisation by cryo-TEM, rheology, light scattering and small-angle neutron scattering. Journal of Pharmaceutical Sciences 100, 536-46. http://dx.doi.org/10.1002/jps.22283

Gaete-Garreton L, Vargas-Hernandez Y, Cares-Pacheco M, Sainz J and Alarcon J (2011) Ultrasonically enhanced extraction of bioactive principles from Quillaja Saponaria Molina. Ultrasonics 51, 581-5.

Gaete-Garretón L, Vargas-Hernández Y, Cares-Pacheco MG, Sainz J and Alarcón J (2011) Ultrasonically enhanced extraction of bioactive principles from Quillaja Saponaria Molina. Ultrasonics 51, 581-5. http://www.sciencedirect.com/science/article/pii/S0041624X10001988

Garçon N, Leroux-Roels G and Cheng W-F (2011) Vaccine adjuvants. Perspectives in Vaccinology 1, 89-113. http://www.sciencedirect.com/science/article/pii/S2210762211000052

Gertsch J, Viveros-Paredes JM and Taylor P (2011) Plant immunostimulants—Scientific paradigm or myth? Journal of Ethnopharmacology 136, 385-91. http://www.sciencedirect.com/science/article/pii/S0378874110004605

Ghazarian H, Idoni B and Oppenheimer SB (2011) A glycobiology review: Carbohydrates, lectins and implications in cancer therapeutics. Acta Histochemica 113, 236-47. http://www.sciencedirect.com/science/article/pii/S0065128110000267

Giannattasio G, Ohta S, Boyce JR, Xing W, Balestrieri B and Boyce JA (2011) The Purinergic G Protein-Coupled Receptor 6 Inhibits Effector T Cell Activation in Allergic Pulmonary Inflammation. J. Immunol. 187, 1486-95. http://www.jimmunol.org/cgi/content/abstract/187/3/1486

Gómez-González S, Torres-Díaz C, Valencia G, Torres-Morales P, Cavieres LA and Pausas JG (2011) Anthropogenic fires increase alien and native annual species in the Chilean coastal matorral. Diversity and Distributions 17, 58-67. http://dx.doi.org/10.1111/j.1472-4642.2010.00728.x

González-Gómez PL, Bozinovic F and Vásquez RA (2011) Elements of episodic-like memory in free-living hummingbirds, energetic consequences. Animal Behaviour 81, 1257-62. http://www.sciencedirect.com/science/article/pii/S0003347211001114

Gupta A, Khajuria A, Singh J, Singh S, Suri KA and Qazi GN (2011) Immunological adjuvant effect of Boswellia serrata (BOS 2000) on specific antibody and cellular response to ovalbumin in mice. International Immunopharmacology 11, 968-75. http://www.sciencedirect.com/science/article/pii/S1567576911001020

Hedayat M, Netea MG and Rezaei N (2011) Targeting of Toll-like receptors: a decade of progress in combating infectious diseases. The Lancet Infectious Diseases 11, 702-12. http://www.sciencedirect.com/science/article/pii/S1473309911700998

Hossain E, Rawani A, Chandra G, Mandal SC and Gupta JK (2011) Larvicidal activity of Dregea volubilis and Bombax malabaricum leaf extracts against the filarial vector Culex quinquefasciatus. Asian Pacific Journal of Tropical Medicine 4, 436-41. http://www.sciencedirect.com/science/article/pii/S1995764511601211

Hsu C-H, Hung S-C, Wu C-Y and Wong C-H (2011) Auf dem Weg zur automatisierten Oligosaccharid- Synthese. Angewandte Chemie 123, 12076-129. http://dx.doi.org/10.1002/ange.201100125

Hsu C-H, Hung S-C, Wu C-Y and Wong C-H (2011) Toward Automated Oligosaccharide Synthesis. Angewandte Chemie International Edition 50, 11872-923. http://dx.doi.org/10.1002/anie.201100125

Jahangiri A, Rasooli I, Gargari SLM, Owlia P, Rahbar MR, Amani J and Khalili S (2011) An in silico DNA vaccine against Listeria monocytogenes. Vaccine 29, 6948-58. http://www.sciencedirect.com/science/article/pii/S0264410X11010723

Jiménez-Peralta FS, Salem AZM, Mejia-Hernández P, González-Ronquillo M, Albarrán-Portillo B, Rojo-Rubio R and Tinoco-Jaramillo JL (2011) Influence of individual and mixed extracts of two tree species on in vitro gas production kinetics of a high concentrate diet fed to growing lambs. Livestock Science 136, 192-200. http://www.sciencedirect.com/science/article/pii/S187114131000524X

Kamalakannan S, Murugan K and Barnard DR (2011) Toxicity of Acalypha indica (Euphorbiaceae) and Achyranthes aspera (Amaranthaceae) leaf extracts to Aedes aegypti (Diptera: Culicidae). Journal of Asia-Pacific Entomology 14, 41-5. http://www.sciencedirect.com/science/article/pii/S122686151000124X

Kiliç E, Font J, Puig R, Çolak S and Çelik D (2011) Chromium recovery from tannery sludge with saponin and oxidative remediation. Journal of Hazardous Materials 185, 456-62. http://www.sciencedirect.com/science/article/pii/S030438941001215X

Liang X-m, Jin Y, Feng J-t and Ke Y-x (2011) Identification and Structure Elucidation of Compounds from Herbal Medicines. In ‘Traditional Herbal Medicine Research Methods’. (Ed.^(Eds  pp. 139-223. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470921340.ch4

Licciardi PV and Underwood JR (2011) Plant-derived medicines: A novel class of immunological adjuvants. International Immunopharmacology 11, 390-8. http://www.sciencedirect.com/science/article/pii/S1567576910003437

McShane H (2011) Tuberculosis vaccines: beyond bacille Calmette-Guerin. Phil Trans R Soc B 366, 2782-9. http://rstb.royalsocietypublishing.org/cgi/content/abstract/366/1579/2782

Mukhopadhyay P, Chakraborty S, Ponnusamy MP, Lakshmanan I, Jain M and Batra SK (2011) Mucins in the pathogenesis of breast cancer: Implications in diagnosis, prognosis and therapy. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1815, 224-40. http://www.sciencedirect.com/science/article/pii/S0304419X11000023

Naarding MA, Falkowska E, Xiao H and Dragic T (2011) Hepatitis C virus soluble E2 in combination with QuilA and CpG ODN induces neutralizing antibodies in mice. Vaccine 29, 2910-7. http://www.sciencedirect.com/science/article/pii/S0264410X11002106

Nagill R and Kaur S (2011) Vaccine candidates for leishmaniasis: A review. International Immunopharmacology 11, 1464-88. http://www.sciencedirect.com/science/article/pii/S1567576911002190

Nalbantsoy A, Nesil T, Erden S, Çalış İ and Bedir E (2011) Adjuvant effects of Astragalus saponins Macrophyllosaponin B and Astragaloside VII. Journal of Ethnopharmacology 134, 897-903. http://www.sciencedirect.com/science/article/pii/S0378874111000699

Nasri S, Ben Salem H, Vasta V, Abidi S, Makkar HPS and Priolo A (2011) Effect of increasing levels of Quillaja saponaria on digestion, growth and meat quality of Barbarine lamb. Animal Feed Science and Technology 164, 71-8. http://www.sciencedirect.com/science/article/pii/S0377840110004256

Newton AC, Echeverría C, Cantarello E and Bolados G (2011) Projecting impacts of human disturbances to inform conservation planning and management in a dryland forest landscape. Biological Conservation 144, 1949-60. http://www.sciencedirect.com/science/article/pii/S0006320711001212

Pedersen G, Major D, Roseby S, Wood J, Madhun AS and Cox RJ (2011) Matrix-M adjuvanted virosomal H5N1 vaccine confers protection against lethal viral challenge in a murine model. Influenza and Other Respiratory Viruses 5, 426-37. http://dx.doi.org/10.1111/j.1750-2659.2011.00256.x

Rajakumar G and Abdul Rahuman A (2011) Larvicidal activity of synthesized silver nanoparticles using Eclipta prostrata leaf extract against filariasis and malaria vectors. Acta Tropica 118, 196-203. http://www.sciencedirect.com/science/article/pii/S0001706X1100060X

Reid S and Armesto JJ (2011) Interaction dynamics of avian frugivores and plants in a Chilean Mediterranean shrubland. Journal of Arid Environments 75, 221-30. http://www.sciencedirect.com/science/article/pii/S0140196310002685

Retamal PM (2011) Nutritional Management of the Prepartum Dairy Cow. In ‘Dairy Production Medicine’. (Ed.^(Eds  pp. 7-17. (Blackwell Publishing Ltd.). http://dx.doi.org/10.1002/9780470960554.ch2

Rey-Ladino J, Ross AG, Cripps AW, McManus DP and Quinn R (2011) Natural products and the search for novel vaccine adjuvants. Vaccine 29, 6464-71. http://www.sciencedirect.com/science/article/pii/S0264410X11010735

Rodriguez-Diaz M, Delporte C, Cartagena C, Cassels B, Gonzalez P, Silva X, Leon F and Wessjohann L (2011) Topical anti-inflammatory activity of quillaic acid from Quillaja saponaria Mol. and some derivatives. J Pharm Pharmacol 63, 718-24.

Rodríguez-Díaz M, Delporte C, Cartagena C, Cassels BK, González P, Silva X, León F and Wessjohann LA (2011) Topical anti-inflammatory activity of quillaic acid from Quillaja saponaria Mol. and some derivatives. Journal of Pharmacy and Pharmacology 63, 718-24. http://dx.doi.org/10.1111/j.2042-7158.2011.01263.x

Rubio-Moraga Á, Gerwig GJ, Castro-Díaz N, Jimeno ML, Escribano J, Fernández J-A and Kamerling JP (2011) Triterpenoid saponins from corms of Crocus sativus: Localization, extraction and characterization. Industrial Crops and Products 34, 1401-9. http://www.sciencedirect.com/science/article/pii/S0926669011001233

Sanchez-Schmitz G and Levy O (2011) Development of Newborn and Infant Vaccines. Science Translational Medicine 3, 90ps27-. http://stm.sciencemag.org

Schiött Ĺ, Larsson K, Manniche S, Kalliomäki S, Heydenreich AV, Dalsgaard K and Kirkby N (2011) Posintro™-HBsAg, a modified ISCOM including HBsAg, induces strong cellular and humoral responses. International Journal of Pharmaceutics 414, 312-20. http://www.sciencedirect.com/science/article/pii/S0378517311004406

Schlesinger ME, King MJ, Sole KC and Davenport WG (2011) Chapter 17 - Electrowinning. In ‘Extractive Metallurgy of Copper (Fifth Edition)’. (Ed.^(Eds  pp. 349-72. (Elsevier: Oxford). http://www.sciencedirect.com/science/article/pii/B9780080967899100174

Schulz JJ, Cayuela L, Rey-Benayas JM and Schröder B (2011) Factors influencing vegetation cover change in Mediterranean Central Chile (1975–2008). Applied Vegetation Science 14, 571-82. http://dx.doi.org/10.1111/j.1654-109X.2011.01135.x

Shakarji RA, He Y and Gregory S (2011) Statistical analysis of the effect of operating parameters on acid mist generation in copper electrowinning. Hydrometallurgy 106, 113-8. http://www.sciencedirect.com/science/article/pii/S0304386X10003397

Sieber R, Schobinger Rehberger B and Walther B (2011) Milk Lipids | Removal of Cholesterol from Dairy Products. In ‘Encyclopedia of Dairy Sciences (Second Edition)’. (Ed.^(Eds Editor-in-Chief:  John WF) pp. 734-40. (Academic Press: San Diego). http://www.sciencedirect.com/science/article/pii/B9780123744074003459

Silva Elipe MV (2011) Hyphenation of NMR with Other Analytical Separation Techniques. In ‘LC-NMR and Other Hyphenated NMR Techniques’. (Ed.^(Eds  pp. 143-78. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118135396.ch6

Silveira F, Cibulski SP, Varela AP, Marqués JM, Chabalgoity A, de Costa F, Yendo ACA, Gosmann G, Roehe PM, Fernández C and Ferreira F (2011) Quillaja brasiliensis saponins are less toxic than Quil A and have similar properties when used as an adjuvant for a viral antigen preparation. Vaccine 29, 9177-82. http://www.sciencedirect.com/science/article/pii/S0264410X11015945

Silveira F, Rossi S, Fernandez C, Gosmann G, Schenkel E and Ferreira F (2011) Alum-type adjuvant effect of non-haemolytic saponins purified from Ilex and Passiflora spp. Phytother Res 25, 1783-8.

Silveira F, Rossi S, Fernández C, Gosmann G, Schenkel E and Ferreira F (2011) Alum-type Adjuvant Effect of Non-haemolytic Saponins Purified from Ilex and Passiflora spp. Phytotherapy Research 25, 1783-8. http://dx.doi.org/10.1002/ptr.3454

Singha S, Banerjee S and Chandra G (2011) Synergistic effect of Croton caudatus (fruits) and Tiliacora acuminata (flowers) extracts against filarial vector Culex quinquefasciatus. Asian Pacific Journal of Tropical Biomedicine 1, S159-S64. http://www.sciencedirect.com/science/article/pii/S2221169111601470

Singha S and Chandra G (2011) Mosquito larvicidal activity of some common spices and vegetable waste on Culex quinquefasciatus and Anopheles stephensi. Asian Pacific Journal of Tropical Medicine 4, 288-93. http://www.sciencedirect.com/science/article/pii/S1995764511600886

Stanimirova R, Marinova K, Tcholakova S, Denkov N, Stoyanov S and Pelan E (2011) Surface rheology of saponin adsorption layers. Langmuir 27, 12486-98.

Sun H, Chen L, Wang J, Wang K and Zhou J (2011) Structure–function relationship of the saponins from the roots of Platycodon grandiflorum for hemolytic and adjuvant activity. International Immunopharmacology 11, 2047-56. http://www.sciencedirect.com/science/article/pii/S1567576911003389

Tam K and Roner M (2011) Characterization of in vivo anti-rotavirus activities of saponin extracts from Quillaja saponaria Molina. Antiviral Res 90, 231-41.

Tam KI and Roner MR (2011) Characterization of in vivo anti-rotavirus activities of saponin extracts from Quillaja saponaria Molina. Antiviral Research 90, 231-41. http://www.sciencedirect.com/science/article/pii/S016635421100283X

Tielemans CL, Vlasak J, Kosa D, Billiouw J-M, Verpooten GA, Mezei I, Ryba M, Peeters PC, Mat O, Jadoul MY, Polakovic V, Dhaene M, Treille S, Kuriyakose SO, Leyssen M, Houard SA and Surquin M (2011) Immunogenicity and safety of an investigational AS02v-adjuvanted hepatitis B vaccine in patients with renal insufficiency who failed to respond or to maintain antibody levels after prior vaccination: Results of two open, randomized, comparative trials. Vaccine 29, 1159-66. http://www.sciencedirect.com/science/article/pii/S0264410X10017470

Tomasula PM and Nutter DW (2011) Chapter 2 - Mitigation of Greenhouse Gas Emissions in the Production of Fluid Milk. In ‘Advances in Food and Nutrition Research’. (Ed.^(Eds Steve LT) pp. 41-88. (Academic Press). http://www.sciencedirect.com/science/article/pii/B9780123859891000028

Van de Ven H, Vermeersch M, Matheeussen A, Vandervoort J, Weyenberg W, Apers S, Cos P, Maes L and Ludwig A (2011) PLGA nanoparticles loaded with the antileishmanial saponin β-aescin: Factor influence study and in vitro efficacy evaluation. International Journal of Pharmaceutics 420, 122-32. http://www.sciencedirect.com/science/article/pii/S0378517311007782

van Zijderveld SM, Dijkstra J, Perdok HB, Newbold JR and Gerrits WJJ (2011) Dietary inclusion of diallyl disulfide, yucca powder, calcium fumarate, an extruded linseed product, or medium-chain fatty acids does not affect methane production in lactating dairy cows. Journal of Dairy Science 94, 3094-104. http://www.sciencedirect.com/science/article/pii/S0022030211002967

Vasta V and Luciano G (2011) The effects of dietary consumption of plants secondary compounds on small ruminants’ products quality. Small Ruminant Research 101, 150-9. http://www.sciencedirect.com/science/article/pii/S0921448811003841

Vázquez-Chagoyán JC, Gupta S and Garg NJ (2011) Chapter 6 - Vaccine Development Against Trypanosoma cruzi and Chagas Disease. In ‘Advances in Parasitology’. (Ed.^(Eds Louis M. Weiss HBT and Louis VK) pp. 121-46. (Academic Press). http://www.sciencedirect.com/science/article/pii/B978012385863400006X

Villalba JJ, Provenza FD, K Clemensen A, Larsen R and Juhnke J (2011) Preference for diverse pastures by sheep in response to intraruminal administrations of tannins, saponins and alkaloids. Grass and Forage Science 66, 224-36. http://dx.doi.org/10.1111/j.1365-2494.2010.00779.x

Wald A, Koelle DM, Fife K, Warren T, LeClair K, Chicz RM, Monks S, Levey DL, Musselli C and Srivastava PK (2011) Safety and immunogenicity of long HSV-2 peptides complexed with rhHsc70 in HSV-2 seropositive persons. Vaccine 29, 8520-9. http://www.sciencedirect.com/science/article/pii/S0264410X11014526

Wang W and Singh M (2011) Selection of Optimal Adjuvants and Product Factors that Affect Vaccine Immunogenicity. In ‘Development of Vaccines’. (Ed.^(Eds  pp. 327-83. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118023648.ch13

Williams AE (2011) Vaccination. In ‘Immunology’. (Ed.^(Eds  pp. 342-62. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9781119998648.ch17

Williams SRO, Moate PJ, Hannah MC, Ribaux BE, Wales WJ and Eckard RJ (2011) Background matters with the SF6 tracer method for estimating enteric methane emissions from dairy cows: A critical evaluation of the SF6 procedure. Animal Feed Science and Technology 170, 265-76. http://www.sciencedirect.com/science/article/pii/S0377840111003798

Wojciechowski K, Piotrowski M, Popielarz W and Sosnowski TR (2011) Short- and mid-term adsorption behaviour of Quillaja Bark Saponin and its mixtures with lysozyme. Food Hydrocolloids 25, 687-93. http://www.sciencedirect.com/science/article/pii/S0268005X10001451

Wursthorn K, Wedemeyer H and Manns MP (2011) Republished paper: Managing HBV in patients with impaired immunity. Postgrad. Med. J. 87, 223-38. http://pmj.bmj.com/cgi/content/abstract/87/1025/223

Zhang S-d, Soltis DE, Yang Y, Li D-z and Yi T-s (2011) Multi-gene analysis provides a well-supported phylogeny of Rosales. Molecular Phylogenetics and Evolution 60, 21-8. http://www.sciencedirect.com/science/article/pii/S1055790311001928

Zhao X, Fan Y, Wang D, Hu Y, Guo L, Ruan S, Zhang J and Yuan J (2011) Immunological adjuvant efficacy of glycyrrhetinic acid liposome against Newcastle disease vaccine. Vaccine 29, 9611-7. http://www.sciencedirect.com/science/article/pii/S0264410X11016902

Zhou YY, Mao HL, Jiang F, Wang JK, Liu JX and McSweeney CS (2011) Inhibition of rumen methanogenesis by tea saponins with reference to fermentation pattern and microbial communities in Hu sheep. Animal Feed Science and Technology 166–167, 93-100. http://www.sciencedirect.com/science/article/pii/S037784011100126X

Zhou Z, Meng Q and Yu Z (2011) Effects of Methanogenic Inhibitors on Methane Production and Abundances of Methanogens and Cellulolytic Bacteria in In Vitro Ruminal Cultures. Appl. Envir. Microbiol. 77, 2634-9. http://aem.asm.org/cgi/content/abstract/77/8/2634

Anonymous (2010) Toxicology and Risk Assessment of Coumarin: Focus on Human Data. In ‘Risk Assessment of Phytochemicals in Food’. (Ed.^(Eds  pp. 272-360. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527634705.ch3c

Altamirano A, Field R, Cayuela L, Aplin P, Lara A and Rey-Benayas JM (2010) Woody species diversity in temperate Andean forests: The need for new conservation strategies. Biological Conservation 143, 2080-91. http://www.sciencedirect.com/science/article/pii/S0006320710002399

Andresen M and Cedergreen N (2010) Plant Growth Is Stimulated by Tea-seed Extract: A New Natural Growth Regulator? HortScience 45, 1848-53. http://hortsci.ashspublications.org/cgi/content/abstract/45/12/1848

Au F, McKeown LE, McAllister TA and Chaves AV (2010) Fermentation characteristics of corn-, triticale-, and wheat-based dried distillers’ grains with solubles in barley-based diets determined using continuous and batch culture systems. Journal of the Science of Food and Agriculture 90, 2074-82. http://dx.doi.org/10.1002/jsfa.4054

Awad E and Austin B (2010) Use of lupin, Lupinus perennis, mango, Mangifera indica, and stinging nettle, Urtica dioica, as feed additives to prevent Aeromonas hydrophila infection in rainbow trout, Oncorhynchus mykiss (Walbaum). Journal of Fish Diseases 33, 413-20. http://dx.doi.org/10.1111/j.1365-2761.2009.01133.x

Bachran D, Schneider S, Bachran C, Urban R, Weng A, Melzig MF, Hoffmann C, Kaufmann AM and Fuchs H (2010) Epidermal growth factor receptor expression affects the efficacy of the combined application of saponin and a targeted toxin on human cervical carcinoma cells. International Journal of Cancer 127, 1453-61. http://dx.doi.org/10.1002/ijc.25123

Bankefors J, Nord L and Kenne L (2010) Multidimensional profiling of components in complex mixtures of natural products for metabolic analysis, proof of concept: application to Quillaja saponins. J Chromatogr B Analyt Technol Biomed Life Sci 878, 471-6.

Bankefors J, Nord LI and Kenne L (2010) Multidimensional profiling of components in complex mixtures of natural products for metabolic analysis, proof of concept: Application to Quillaja saponins. Journal of Chromatography B 878, 471-6. http://www.sciencedirect.com/science/article/pii/S157002320900796X

Borja-Cabrera GP, Santos FN, Santos FB, Trivellato FAdA, Kawasaki JKA, Costa AC, Castro T, Nogueira FS, Moreira MAB, Luvizotto MCR, Palatnik M and Palatnik-de-Sousa CB (2010) Immunotherapy with the saponin enriched-Leishmune® vaccine versus immunochemotherapy in dogs with natural canine visceral leishmaniasis. Vaccine 28, 597-603. http://www.sciencedirect.com/science/article/pii/S0264410X09014182

Cares MG, Vargas Y, Gaete L, Sainz J and Alarcón J (2010) Ultrasonically assisted extraction of bioactive principles from Quillaja Saponaria Molina. Physics Procedia 3, 169-78. http://www.sciencedirect.com/science/article/pii/S1875389210000258

Costa CTC, Bevilaqua CML, Morais SM, Camurça-Vasconcelos ALF, Maciel MV, Braga RR and Oliveira LMB (2010) Anthelmintic activity of Cocos nucifera L. on intestinal nematodes of mice. Research in Veterinary Science 88, 101-3. http://www.sciencedirect.com/science/article/pii/S0034528809001350

Davis BL, Fraser JN, Burkey TE, Skjolaas KA, Dritz SS, Johnson BJ and Minton JE (2010) Oral inoculation with Salmonella enterica serovar Typhimurium or Choleraesuis promotes divergent responses in the somatotropic growth axis of swine. J Anim Sci 88, 1642-8. http://www.journalofanimalscience.org/cgi/content/abstract/88/5/1642

Del Giudice G and Rappuoli R (2010) Adjuvants and Subunit Vaccines. In ‘Topley & Wilson’s Microbiology and Microbial Infections’. (Ed.^(Eds  pp. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9780470688618.taw0126

Fink-Gremmels J (2010) Defense mechanisms against toxic phytochemicals in the diet of domestic animals. Molecular Nutrition & Food Research 54, 249-58. http://dx.doi.org/10.1002/mnfr.200900361

Gane E (2010) Hepatitis B immunoglobulin immunoprophylaxis for hepatitis B: High, low, or no dose?1. Liver Transplantation 16, S36-S9. http://dx.doi.org/10.1002/lt.22151

Gebru E, Lee JS, Son JC, Yang SY, Shin SA, Kim B, Kim MK and Park SC (2010) Effect of probiotic-, bacteriophage-, or organic acid-supplemented feeds or fermented soybean meal on the growth performance, acute-phase response, and bacterial shedding of grower pigs challenged with Salmonella enterica serotype Typhimurium. J Anim Sci 88, 3880-6. http://www.journalofanimalscience.org/cgi/content/abstract/88/12/3880

Geert L-R (2010) Unmet needs in modern vaccinology: Adjuvants to improve the immune response. Vaccine 28, Supplement 3, C25-C36. http://www.sciencedirect.com/science/article/pii/S0264410X10010042

Goiri I, Oregui LM and Garcia-Rodriguez A (2010) Use of chitosans to modulate ruminal fermentation of a 50:50 forage-to-concentrate diet in sheep. J Anim Sci 88, 749-55. http://www.journalofanimalscience.org/cgi/content/abstract/88/2/749

Hassan SM, Haq AU, Byrd JA, Berhow MA, Cartwright AL and Bailey CA (2010) Haemolytic and antimicrobial activities of saponin-rich extracts from guar meal. Food Chemistry 119, 600-5. http://www.sciencedirect.com/science/article/pii/S0308814609008747

Heldens JGM, Pouwels HGW, Derks CGG, Van de Zande SMA and Hoeijmakers MJH (2010) Duration of immunity induced by an equine influenza and tetanus combination vaccine formulation adjuvanted with ISCOM-Matrix. Vaccine 28, 6989-96. http://www.sciencedirect.com/science/article/pii/S0264410X10011886

Hu K, Berenjian S, Larsson R, Gullbo J, Nygren P, Lovgren T and Morein B (2010) Nanoparticulate Quillaja saponin induces apoptosis in human leukemia cell lines with a high therapeutic index. Int J Nanomedicine 5, 51-62.

José-Luis R (2010) Effects of triterpenes on the immune system. Journal of Ethnopharmacology 128, 1-14. http://www.sciencedirect.com/science/article/pii/S0378874110000255

Kim S-H, Seo K-W, Kim J, Lee K-Y and Jang Y-S (2010) The M Cell-Targeting Ligand Promotes Antigen Delivery and Induces Antigen-Specific Immune Responses in Mucosal Vaccination. J. Immunol. 185, 5787-95. http://www.jimmunol.org/cgi/content/abstract/185/10/5787

Krogdahl Ĺ, Penn M, Thorsen J, Refstie S and Bakke AM (2010) Important antinutrients in plant feedstuffs for aquaculture: an update on recent findings regarding responses in salmonids. Aquaculture Research 41, 333-44. http://dx.doi.org/10.1111/j.1365-2109.2009.02426.x

Labriola L and Jadoul M (2010) The decades-long fight against HBV transmission to dialysis patients: slow but definite progress. Nephrol. Dial. Transplant. 25, 2047-9. http://ndt.oxfordjournals.org

Lepenies B, Yin J and Seeberger PH (2010) Applications of synthetic carbohydrates to chemical biology. Current Opinion in Chemical Biology 14, 404-11. http://www.sciencedirect.com/science/article/pii/S1367593110000219

Leroux-Roels I, Leroux-Roels G, Ofori-Anyinam O, Moris P, De Kock E, Clement F, Dubois M-C, Koutsoukos M, Demoitie M-A, Cohen J and Ballou WR (2010) Evaluation of the Safety and Immunogenicity of Two Antigen Concentrations of the Mtb72F/AS02A Candidate Tuberculosis Vaccine in Purified Protein Derivative-Negative Adults. Clin. Vaccine Immunol. 17, 1763-71. http://cvi.asm.org/cgi/content/abstract/17/11/1763

Lye H-S, Rahmat-Ali GR and Liong M-T (2010) Mechanisms of cholesterol removal by lactobacilli under conditions that mimic the human gastrointestinal tract. International Dairy Journal 20, 169-75. http://www.sciencedirect.com/science/article/pii/S0958694609001903

Man S, Gao W, Zhang Y, Huang L and Liu C (2010) Chemical study and medical application of saponins as anti-cancer agents. Fitoterapia 81, 703-14. http://www.sciencedirect.com/science/article/pii/S0367326X10001346

Moreno-Mendieta SA, Rocha-Zavaleta L and Rodriguez-Sanoja R (2010) Adjuvants in tuberculosis vaccine development. FEMS Immunology & Medical Microbiology 58, 75-84. http://dx.doi.org/10.1111/j.1574-695X.2009.00629.x

Nicholls EF, Madera L and Hancock REW (2010) Immunomodulators as adjuvants for vaccines and antimicrobial therapy. Annals of the New York Academy of Sciences 1213, 46-61. http://dx.doi.org/10.1111/j.1749-6632.2010.05787.x

Patil SV, Salunke BK, Patil CD, Salunkhe RB, Gavit P and Maheshwari VL (2010) Potential of extracts of the tropical plant Balanites aegyptiaca (L) Del. (Balanitaceae) to control the mealy bug, Maconellicoccus hirsutus (Homoptera: Pseudococcidae). Crop Protection 29, 1293-6. http://www.sciencedirect.com/science/article/pii/S0261219410001560

Patra AK (2010) Meta-analyses of effects of phytochemicals on digestibility and rumen fermentation characteristics associated with methanogenesis. Journal of the Science of Food and Agriculture 90, 2700-8. http://dx.doi.org/10.1002/jsfa.4143

Patra AK and Saxena J (2010) A new perspective on the use of plant secondary metabolites to inhibit methanogenesis in the rumen. Phytochemistry 71, 1198-222. http://www.sciencedirect.com/science/article/pii/S0031942210001858

Qiu Y-L, Li L, Wang B, Xue J-Y, Hendry TA, Li R-Q, Brown JW, Liu Y, Hudson GT and Chen Z-D (2010) Angiosperm phylogeny inferred from sequences of four mitochondrial genes. Journal of Systematics and Evolution 48, 391-425. http://dx.doi.org/10.1111/j.1759-6831.2010.00097.x

Ragupathi G, Damani P, Deng K, Adams M, Hang J, George C, Livingston P and Gin D (2010) Preclinical evaluation of the synthetic adjuvant SQS-21 and its constituent isomeric saponins. Vaccine 28, 4260-7.

Ragupathi G, Damani P, Deng K, Adams MM, Hang J, George C, Livingston PO and Gin DY (2010) Preclinical evaluation of the synthetic adjuvant SQS-21 and its constituent isomeric saponins. Vaccine 28, 4260-7. http://www.sciencedirect.com/science/article/pii/S0264410X10005402

Roner M, Tam K and Kiesling-Barrager M (2010) Prevention of rotavirus infections in vitro with aqueous extracts of Quillaja Saponaria Molina. Future Med Chem 2, 1083-97.

Salem AZM, Robinson PH, López S, Gohar YM, Rojo R and Tinoco JL (2010) Sensitivity of sheep intestinal lactic acid bacteria to secondary compounds extracted from Acacia saligna leaves. Animal Feed Science and Technology 161, 85-93. http://www.sciencedirect.com/science/article/pii/S0377840110002415

Serabian MA, Huang Y and Gad SC (2010) Preclinical Safety Evaluation of Biopharmaceuticals. In ‘Pharmaceutical Sciences Encyclopedia’. (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470571224.pse191

Sharp FA, Lavelle EC and Gad SC (2010) Discovery of Vaccine Adjuvants. In ‘Pharmaceutical Sciences Encyclopedia’. (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470571224.pse438

Sun Y, Liu J, Yu H and Gong C (2010) Isolation and evaluation of immunological adjuvant activities of saponins from the roots of Pulsatilla chinensis with less adverse reactions. International Immunopharmacology 10, 584-90. http://www.sciencedirect.com/science/article/pii/S1567576910000652

Vega-GÁLvez A, San MartÍN R, Sanders M, Miranda M and Lara E (2010) CHARACTERISTICS AND MATHEMATICAL MODELING OF CONVECTIVE DRYING OF QUINOA (CHENOPODIUM QUINOA WILLD.): INFLUENCE OF TEMPERATURE ON THE KINETIC PARAMETERS. Journal of Food Processing and Preservation 34, 945-63. http://dx.doi.org/10.1111/j.1745-4549.2009.00410.x

Vlaminck J, Lopez-Aban J, Ruano A, del Olmo E and Muro A (2010) Vaccination against Strongyloides venezuelensis with homologue antigens using new immunomodulators. J Parasitol 96, 643-7.

Wayhs CAY, Manfredini V, Sitta A, Deon M, Ribas GS, Vanzin CS, Biancini GB, Nin MS, Barros HMT and Vargas CR (2010) Effects of insulin and clonazepam on DNA damage in diabetic rats submitted to the forced swimming test. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 703, 187-90. http://www.sciencedirect.com/science/article/pii/S1383571810003086

Wursthorn K, Wedemeyer H and Manns MP (2010) Managing HBV in patients with impaired immunity. Gut 59, 1430-45. http://gut.bmj.com/cgi/content/abstract/59/10/1430

Xu M, Rinker M, McLeod KR and Harmon DL (2010) Yucca schidigera extract decreases in vitro methane production in a variety of forages and diets. Animal Feed Science and Technology 159, 18-26. http://www.sciencedirect.com/science/article/pii/S0377840110001732

Y O (2010) Mechanisms of nematode suppression by organic soil amendments—A review. Applied Soil Ecology 44, 101-15. http://www.sciencedirect.com/science/article/pii/S0929139309001942

Zasada IA, Walters TW and Pinkerton JN (2010) Post-Plant Nematicides for the Control of Root Lesion Nematode in Red Raspberry. HortTechnology 20, 856-62. http://horttech.ashspublications.org/cgi/content/abstract/20/5/856

Anonymous (2009) Erratum to “Feeding saponin-containing Yucca schidigera and Quillaja saponaria to decrease enteric methane production in dairy cows” (J. Dairy Sci. 92:2809–2821). Journal of Dairy Science 92, 3543. http://www.sciencedirect.com/science/article/pii/S0022030209706757

Anonymous (2009) Current literature in diabetes. Diabetes/Metabolism Research and Reviews 25, i-viii. http://dx.doi.org/10.1002/dmrr.952

Anonymous (2009) Erratum to “Feeding saponin-containing Yucca schidigera and Quillaja saponaria to decrease enteric methane production in dairy cows” (J. Dairy Sci. 92:2809–2821). Journal of Dairy Science 92, 3543. http://www.sciencedirect.com/science/article/pii/S0022030209706757

Adams LG, Babiuk L, McGavin D, Nordgren R, Alan DTB and Lawrence RS (2009) Chapter 16 - Special Issues around Veterinary Vaccines. In ‘Vaccines for Biodefense and Emerging and Neglected Diseases’. (Ed.^(Eds  pp. 225-54. (Academic Press: London). http://www.sciencedirect.com/science/article/pii/B9780123694089000160

Afrose S, Hossain MS, Maki T and Tsujii H (2009) Karaya root saponin exerts a hypocholesterolemic response in rats fed a high-cholesterol diet. Nutrition Research 29, 350-4. http://www.sciencedirect.com/science/article/pii/S0271531709000864

Alan DTB and Lawrence RS (2009) Index. In ‘Vaccines for Biodefense and Emerging and Neglected Diseases’. (Ed.^(Eds  pp. 1451-78. (Academic Press: London). http://www.sciencedirect.com/science/article/pii/B9780123694089000809

Alving CR, Alan DTB and Lawrence RS (2009) Chapter 9 - Vaccine Adjuvants. In ‘Vaccines for Biodefense and Emerging and Neglected Diseases’. (Ed.^(Eds  pp. 115-29. (Academic Press: London). http://www.sciencedirect.com/science/article/pii/B9780123694089000093

AraÚjo MrSS, de Andrade RA, Sathler-Avelar R, Teixeira-Carvalho Aa, Andrade MiC, Vianna LR, Mayrink W, Reis AB, Malaquias LCC, Mello MN and Martins-Filho OA (2009) T-cell-derived cytokines, nitric oxide production by peripheral blood monocytes and seric anti-Leishmania (Leishmania) chagasi IgG subclass patterns following immunization against canine visceral leishmaniasis using Leishvaccine and Leishmune®. Vaccine 27, 1008-17. http://www.sciencedirect.com/science/article/pii/S0264410X08016848

Arabski M, WÄ…sik Sa, Dworecki K and Kaca Wa (2009) Laser interferometric and cultivation methods for measurement of colistin/ampicilin and saponin interactions with smooth and rough of Proteus mirabilis lipopolysaccharides and cells. Journal of Microbiological Methods 77, 178-83. http://www.sciencedirect.com/science/article/pii/S0167701209000396

Arabski M, Wąsik S, Dworecki K and Kaca W (2009) Laser interferometric and cultivation methods for measurement of colistin/ampicilin and saponin interactions with smooth and rough of Proteus mirabilis lipopolysaccharides and cells. Journal of Microbiological Methods 77, 178-83. http://www.sciencedirect.com/science/article/pii/S0167701209000396

Baur X (2009) Airborne Allergens and Irritants in the Workplace. In ‘Allergy and Allergic Diseases’. (Ed.^(Eds  pp. 1017-122. (Wiley-Blackwell). http://dx.doi.org/10.1002/9781444300918.ch49

Beckebaum S, Sotiropoulos GC, Gerken G and Cicinnati VR (2009) Hepatitis B and liver transplantation: 2008 update. Reviews in Medical Virology 19, 7-29. http://dx.doi.org/10.1002/rmv.595

Benchaar C and Chouinard PY (2009) Short communication: Assessment of the potential of cinnamaldehyde, condensed tannins, and saponins to modify milk fatty acid composition of dairy cows. Journal of Dairy Science 92, 3392-6. http://www.sciencedirect.com/science/article/pii/S0022030209706563

Bender GS, Eskalen A and Tanizaki G (2009) Evaluation of Potassium Silicate and Quillaja saponaria Extract for Control of Phytophthora cinnamomi Root Rot of Avocado. Proceedings of the ... annual meeting of the Florida State Horticultural Society., 122.

Bhatia V, Wen J-J, Zacks MA, Jain Garg N, Alan DTB and Lawrence RS (2009) Chapter 69 - American Trypanosomiasis. In ‘Vaccines for Biodefense and Emerging and Neglected Diseases’. (Ed.^(Eds  pp. 1423-50. (Academic Press: London). http://www.sciencedirect.com/science/article/pii/B978012369408900069X

Breman JG and Plowe CV (2009) A Malaria Vaccine for Control: More Progress. The Journal of Infectious Disease 200, 317-20. http://jid.oxfordjournals.org/

Burkey TE, Skjolaas KA, Dritz SS and Minton JE (2009) Expression of porcine Toll-like receptor 2, 4 and 9 gene transcripts in the presence of lipopolysaccharide and Salmonella enterica serovars Typhimurium and Choleraesuis. Veterinary Immunology and Immunopathology 130, 96-101. http://www.sciencedirect.com/science/article/pii/S0165242708008143

Chen D-S (2009) Hepatitis B vaccination: The key towards elimination and eradication of hepatitis B. Journal of Hepatology 50, 805-16. http://www.sciencedirect.com/science/article/pii/S0168827809000579

Coler RN, Carter D, Friede M and Reed SG (2009) Adjuvants for malaria vaccines. Parasite Immunology 31, 520-8. http://dx.doi.org/10.1111/j.1365-3024.2009.01142.x

Csaba N, Garcia-Fuentes M and Alonso MJ (2009) Nanoparticles for nasal vaccination. Advanced Drug Delivery Reviews 61, 140-57. http://www.sciencedirect.com/science/article/pii/S0169409X08002640

DÍaz-Forestier J, GÓmez M and Montenegro G (2009) Nectar volume and floral entomofauna as a tool for the implementation of sustainable apicultural management plans in Quillaja saponaria Mol. Agroforestry systems. 76, 149-62. http://dx.doi.org/10.1007/s10457-008-9193-7

Daines AM, Greatrex BW, Hayman CM, Hook SM, McBurney WT, Rades T, Rendle PM and Sims IM (2009) Mannosylated saponins based on oleanolic and glycyrrhizic acids. Towards synthetic colloidal antigen delivery systems. Bioorganic & Medicinal Chemistry 17, 5207-18. http://www.sciencedirect.com/science/article/pii/S0968089609004957

DerbrÉ Sv (2009) Emploi de la phytothÉrapie et de l’aromathÉrapie en prÉvention et traitement des dermatomycoses. ActualitÉs Pharmaceutiques 48, 19-20. http://www.sciencedirect.com/science/article/pii/S0515370009704100

Dewick PM (2009) The Mevalonate and Methylerythritol Phosphate Pathways: Terpenoids and Steroids. In ‘Medicinal Natural Products’. (Ed.^(Eds  pp. 187-310. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9780470742761.ch5

Dewick PM (2009) Index. In ‘Medicinal Natural Products’. (Ed.^(Eds  pp. 509-39. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9780470742761.index

Eloff JN and McGaw LJ (2009) Application of Plant Extracts and Products in Veterinary Infections. In ‘New Strategies Combating Bacterial Infection’. (Ed.^(Eds  pp. 205-28. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527622931.ch8

Estein SM, Fiorentino MaA, Paolicchi FA, Clausse Ma, Manazza J, Cassataro J, Giambartolomei GH, Coria LM, Zylberman V, Fossati CA, Kjeken R and Goldbaum FA (2009) The polymeric antigen BLSOmp31 confers protection against Brucella ovis infection in rams. Vaccine 27, 6704-11. http://www.sciencedirect.com/science/article/pii/S0264410X09013061

Faisal SM, Yan W, McDonough SP and Chang Y-F (2009) Leptospira immunoglobulin-like protein A variable region (LigAvar) incorporated in liposomes and PLGA microspheres produces a robust immune response correlating to protective immunity. Vaccine 27, 378-87. http://www.sciencedirect.com/science/article/pii/S0264410X08015041

FarÍas F, Orlando J, Bravo L, Guevara R and CarÚ M (2009) Comparison of soil bacterial communities associated with actinorhizal, non-actinorhizal plants and the interspaces in the sclerophyllous matorral from Central Chile in two different seasons. Journal of Arid Environments 73, 1117-24. http://www.sciencedirect.com/science/article/pii/S0140196309001815

Figueroa JA, Cavieres LA, GÓmez-GonzÁlez S, Montenegro MM and Jaksic FM (2009) Do heat and smoke increase emergence of exotic and native plants in the matorral of central Chile? Acta Oecologica 35, 335-40. http://www.sciencedirect.com/science/article/pii/S1146609X08001926

Haçarız O, Sayers G, McCullough M, Garrett M, O’Donovan J and Mulcahy G (2009) The effect of Quil A adjuvant on the course of experimental Fasciola hepatica infection in sheep. Vaccine 27, 45-50. http://www.sciencedirect.com/science/article/pii/S0264410X08014229

Haçarız O, Sayers G, McCullough M, Garrett M, O’Donovan J and Mulcahy G (2009) The effect of Quil A adjuvant on the course of experimental Fasciola hepatica infection in sheep. Vaccine 27, 45-50. http://www.sciencedirect.com/science/article/pii/S0264410X08014229

Harvey DJ (2009) Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: An update for 2003–2004. Mass Spectrometry Reviews 28, 273-361. http://dx.doi.org/10.1002/mas.20192

Hecht M-L, Stallforth P, Silva DV, Adibekian A and Seeberger PH (2009) Recent advances in carbohydrate-based vaccines. Current Opinion in Chemical Biology 13, 354-9. http://www.sciencedirect.com/science/article/pii/S1367593109000726

Heldens JGM, Pouwels HGW, Derks CGG, Van de Zande SMA and Hoeijmakers MJH (2009) The first safe inactivated equine influenza vaccine formulation adjuvanted with ISCOM-Matrix that closes the immunity gap. Vaccine 27, 5530-7. http://www.sciencedirect.com/science/article/pii/S0264410X09009591

Heriazon A, Thompson KA, Wilkie BN, Mathes-Sears W, Quinton M and Mallard BA (2009) Antibody to ovalbumin and delayed-type hypersensitivity to Candida albicans and mycobacteria in lactating Holstein cows using Quil A or Freund’s complete adjuvant. Veterinary Immunology and Immunopathology 127, 220-7. http://www.sciencedirect.com/science/article/pii/S0165242708003772

Hladki AI and Romero AI (2009) Taxonomic and nomenclatural aspects of Hypoxylon taxa from southern South America proposed by Spegazzini. Mycologia 101, 733-44. http://www.mycologia.org/cgi/content/abstract/101/5/733

Holtshausen L, Chaves AV, Beauchemin KA, McGinn SM, McAllister TA, Cheeke PR and Benchaar C (2009) Feeding saponin-containing Yucca schidigera and Quillaja saponaria to decrease enteric methane production in dairy cows. Journal of dairy science. 92, 2809-21.

Holtshausen L, Chaves AV, Beauchemin KA, McGinn SM, McAllister TA, Odongo NE, Cheeke PR and Benchaar C (2009) Feeding saponin-containing Yucca schidigera and Quillaja saponaria to decrease enteric methane production in dairy cows. Journal of Dairy Science 92, 2809-21. http://www.sciencedirect.com/science/article/pii/S0022030209705983

Israeli E, Agmon-Levin N, Blank M and Shoenfeld Y (2009) Adjuvants and autoimmunity. Lupus 18, 1217-25. http://lup.sagepub.com/cgi/content/abstract/18/13/1217

Lambrecht BN, Kool M, Willart MAM and Hammad H (2009) Mechanism of action of clinically approved adjuvants. Current Opinion in Immunology 21, 23-9. http://www.sciencedirect.com/science/article/pii/S0952791509000089

Little C, Lara A, McPhee J and Urrutia R (2009) Revealing the impact of forest exotic plantations on water yield in large scale watersheds in South-Central Chile. Journal of Hydrology 374, 162-70. http://www.sciencedirect.com/science/article/pii/S0022169409003345

Liu Y, Guo Z, Feng J, Xue X, Zhang F, Xu Q and Liang X (2009) Development of orthogonal two-dimensional hydrophilic interaction chromatography systems with the introduction of novel stationary phases. Journal of Separation Science 32, 2871-6. http://dx.doi.org/10.1002/jssc.200900086

Lundgren JG (2009) Nutritional aspects of non-prey foods in the life histories of predaceous Coccinellidae. Biological Control 51, 294-305. http://www.sciencedirect.com/science/article/pii/S104996440900139X

Lyke KE, Daou M, Diarra I, Kone A, Kouriba B, Thera MA, Dutta S, Lanar DE, Heppner Jr DG, Doumbo OK, Plowe CV and Sztein MB (2009) Cell-mediated immunity elicited by the blood stage malaria vaccine apical membrane antigen 1 in Malian adults: Results of a Phase I randomized trial. Vaccine 27, 2171-6. http://www.sciencedirect.com/science/article/pii/S0264410X09001601

Madhun AS, Haaheim LR, Nilsen MV and Cox RJ (2009) Intramuscular Matrix-M-adjuvanted virosomal H5N1 vaccine induces high frequencies of multifunctional Th1 CD4+ cells and strong antibody responses in mice. Vaccine 27, 7367-76. http://www.sciencedirect.com/science/article/pii/S0264410X09013784

Malafaia G, Serafim TD, Silva ME, Pedrosa ML and Rezende SA (2009) Protein-energy malnutrition decreases immune response to Leishmania chagasi vaccine in BALB/c mice. Parasite Immunology 31, 41-9. http://dx.doi.org/10.1111/j.1365-3024.2008.01069.x

Martínez EA, Veas E, Jorquera C, San Martín R and Jara P (2009) Re-Introduction of Quínoa into Arid Chile: Cultivation of Two Lowland Races under Extremely Low Irrigation. Journal of Agronomy and Crop Science 195, 1-10. http://dx.doi.org/10.1111/j.1439-037X.2008.00332.x

Maurer V, Perler E and Heckendorn F (2009) In vitro efficacies of oils, silicas and plant preparations against the poultry red mite Dermanyssus gallinae. Exp Appl Acarol 48, 31-41.

Muñoz C, Monreal C, Schnitzer M and Zagal E (2009) Analysis of soil humic acids in particle size fractions of an alfisol from a Mediterranean-type climate. Geoderma 151, 199-203. http://www.sciencedirect.com/science/article/pii/S0016706109001244

Muthana S, Cao H and Chen X (2009) Recent progress in chemical and chemoenzymatic synthesis of carbohydrates. Current Opinion in Chemical Biology 13, 573-81. http://www.sciencedirect.com/science/article/pii/S1367593109001355

Nico D, Claser C, Rodrigues MM, Soares IS and Palatnik-de-Sousa CB (2009) Cloning of the Nucleoside hydrolase of Leishmania donovani aiming at the development of a synthetic vaccine against visceral leishmaniasis. Procedia in Vaccinology 1, 115-9. http://www.sciencedirect.com/science/article/pii/S1877282X09000526

Pham HL, Ross BP, McGeary RP, Shaw PN and Davies NM (2009) Synthesis of cationic derivatives of Quil A and the preparation of cationic immune-stimulating complexes (ISCOMs). International Journal of Pharmaceutics 376, 123-33. http://www.sciencedirect.com/science/article/pii/S0378517309002117

Reed SG, Bertholet S, Coler RN and Friede M (2009) New horizons in adjuvants for vaccine development. Trends in Immunology 30, 23-32. http://www.sciencedirect.com/science/article/pii/S147149060800255X

Sacarlal J, Aide P, Aponte JJ, Renom M, Leach A, Mandomando I, Lievens M, Bassat Q, Lafuente S, Macete E, Vekemans J, Guinovart C, Sigauque B, Sillman M, Milman J, Dubois M-C, Demoitie M-A, Thonnard J, Menendez C, Ballou WR, Cohen J and Alonso PL (2009) Long-Term Safety and Efficacy of the RTS,S/AS02A Malaria Vaccine in Mozambican Children. The Journal of Infectious Disease 200, 329-36. http://jid.oxfordjournals.org//cgi/content/abstract/200/3/329

Sivakumar S and Subramanian SP (2009) Pancreatic tissue protective nature of D-Pinitol studied in streptozotocin-mediated oxidative stress in experimental diabetic rats. European Journal of Pharmacology 622, 65-70. http://www.sciencedirect.com/science/article/pii/S0014299909007870

Skurtys O and Aguilera JM (2009) Formation of O/W macroemulsions with a circular microfluidic device using saponin and potato starch. Food Hydrocolloids 23, 1810-7. http://www.sciencedirect.com/science/article/pii/S0268005X09000216

Smoot JT, Demchenko AV and Derek H (2009) Chapter 5 Oligosaccharide Synthesis: From Conventional Methods to Modern Expeditious Strategies. In ‘Advances in Carbohydrate Chemistry and Biochemistry’. (Ed.^(Eds  pp. 161-250. (Academic Press). http://www.sciencedirect.com/science/article/pii/S0065231809000055

Song X and Hu S (2009) Adjuvant activities of saponins from traditional Chinese medicinal herbs. Vaccine 27, 4883-90. http://www.sciencedirect.com/science/article/pii/S0264410X09008809

Song X, Zang L and Hu S (2009) Amplified immune response by ginsenoside-based nanoparticles (ginsomes). Vaccine 27, 2306-11. http://www.sciencedirect.com/science/article/pii/S0264410X09002886

Souza LOP and Palatnik de Sousa CB (2009) The Nucleoside hydrolase DNA vaccine VR1012NH36 in prophylactic vaccination against mice tegumentar leishmaniasis. Procedia in Vaccinology 1, 120-3. http://www.sciencedirect.com/science/article/pii/S1877282X09000538

Stick RV and Williams SJ (2009) Chapter 12 - Classics in Carbohydrate Chemistry and Glycobiology. In ‘Carbohydrates: The Essential Molecules of Life (Second Edition)’. (Ed.^(Eds  pp. 413-43. (Elsevier: Oxford). http://www.sciencedirect.com/science/article/pii/B9780240521183000120

Sun HX, Xie Y and Ye YP (2009) Advances in saponin-based adjuvants. Vaccine 27, 1787-96.

Sun H-X, Wang H, Xu H-s and Ni Y (2009) Novel polysaccharide adjuvant from the roots of Actinidia eriantha with dual Th1 and Th2 potentiating activity. Vaccine 27, 3984-91. http://www.sciencedirect.com/science/article/pii/S0264410X09005829

Sun H-X, Xie Y and Ye Y-P (2009) Advances in saponin-based adjuvants. Vaccine 27, 1787-96. http://www.sciencedirect.com/science/article/pii/S0264410X09001443

Sun H-X, Xie Y and Ye Y-P (2009) ISCOMs and ISCOMATRIX™. Vaccine 27, 4388-401. http://www.sciencedirect.com/science/article/pii/S0264410X09007038

Sun H-X, Xie Y and Ye Y-P (2009) ISCOMs and ISCOMATRIX™. Vaccine 27, 4388-401. http://www.sciencedirect.com/science/article/pii/S0264410X09007038

Sun Y-X (2009) Immunological Adjuvant Effect of a Water-Soluble Polysaccharide, CPP, from the Roots of Codonopsis pilosula on the Immune Responses to Ovalbumin in Mice. Chemistry & Biodiversity 6, 890-6. http://dx.doi.org/10.1002/cbdv.200800154

Vekemans J, Leach A and Cohen J (2009) Development of the RTS,S/AS malaria candidate vaccine. Vaccine 27, Supplement 6, G67-G71. http://www.sciencedirect.com/science/article/pii/S0264410X0901528X

Walker LE, Vang L, Shen X, Livingston BD, Post P, Sette A, Godin CS and Newman MJ (2009) Design and preclinical development of a recombinant protein and DNA plasmid mixed format vaccine to deliver HIV-derived T-lymphocyte epitopes. Vaccine 27, 7087-95. http://www.sciencedirect.com/science/article/pii/S0264410X09013930

Wilson-Welder JH, Torres MP, Kipper MJ, Mallapragada SK, Wannemuehler MJ and Narasimhan B (2009) Vaccine adjuvants: Current challenges and future approaches. Journal of Pharmaceutical Sciences 98, 1278-316. http://dx.doi.org/10.1002/jps.21523

Xiao C, Bao G and Hu S (2009) Enhancement of immune responses to Newcastle disease vaccine by a supplement of extract of Momordica cochinchinensis (Lour.) Spreng. seeds. Poult. Sci. 88, 2293-7. http://ps.fass.org/cgi/content/abstract/88/11/2293

Xie Y, Sun H-X and Li D (2009) Platycodin D is a potent adjuvant of specific cellular and humoral immune responses against recombinant hepatitis B antigen. Vaccine 27, 757-64. http://www.sciencedirect.com/science/article/pii/S0264410X08015508

Yu B and Sun J (2009) Current Synthesis of Triterpene Saponins. Chemistry – An Asian Journal 4, 642-54. http://dx.doi.org/10.1002/asia.200800462

Zheng C, Hao H, Wang X, Wu X, Wang G, Sang G, Liang Y, Xie L, Xia C and Yao X (2009) Diagnostic fragment-ion-based extension strategy for rapid screening and identification of serial components of homologous families contained in traditional Chinese medicine prescription using high-resolution LC-ESI- IT-TOF/MS: Shengmai injection as an example. Journal of Mass Spectrometry 44, 230-44. http://dx.doi.org/10.1002/jms.1502

Anonymous (2008) Current literature in mass spectrometry. Journal of Mass Spectrometry 43, 1151-60. http://dx.doi.org/10.1002/jms.1305

Anonymous (2008) Index. In ‘Carbohydrate-Based Vaccines and Immunotherapies’. (Ed.^(Eds  pp. 395-408. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470473283.index

Anonymous (2008) Current Awareness in Phytochemical Analysis. Phytochemical Analysis 19, 471-8. http://dx.doi.org/10.1002/pca.1040

Baez J (2008) Biopharmaceuticals Derived from Transgenic Plants and Animals. In ‘Modern Biopharmaceuticals’. (Ed.^(Eds  pp. 833-92. (Wiley-VCH Verlag GmbH). http://dx.doi.org/10.1002/9783527620982.ch35

Bankefors J, Nord LI and Kenne L (2008) Structural classification of Quillaja saponins by electrospray ionization ion trap multiple-stage mass spectrometry in combination with multivariate analysis, proof of concept. Chemometrics and Intelligent Laboratory Systems 90, 178-87. http://www.sciencedirect.com/science/article/pii/S0169743907001967

Bankefors J, Nord LI and Kenne L (2008) Structural classification of acyl-substituted Quillaja saponins by electrospray ionisation ion trap multiple-stage mass spectrometry in combination with multivariate analysis. Rapid Commun Mass Spectrom 22, 3851-60.

Bello MA, Hawkins JA and Rudall PJ (2008) Floral Morphology and Development in Quillajaceae and Surianaceae (Fabales), the Species-poor Relatives of Leguminosae and Polygalaceae. Ann. Bot. 101, 1433-4. http://aob.oxfordjournals.org/cgi/content/abstract/101/9/1433

Bello MA, Hawkins JA, Rudall PJ, Bello MA, Hawkins JA and Rudall PJ (2008) Floral Morphology and Development in Quillajaceae and Surianaceae (Fabales), the Species-poor Relatives of Leguminosae and Polygalaceae. Ann. Bot. 101, 1433-4. http://aob.oxfordjournals.org/cgi/content/abstract/101/9/1433

Borja-Cabrera GP, Santos FN, Bauer FS, Parra LE, Menz I, Morgado AA, Soares IS, Batista LMM and Palatnik-de-Sousa CB (2008) Immunogenicity assay of the Leishmune® vaccine against canine visceral leishmaniasis in Brazil. Vaccine 26, 4991-7. http://www.sciencedirect.com/science/article/pii/S0264410X08009730

Breitmaier E (2008) Triterpene. In ‘Terpene’. (Ed.^(Eds  pp. 85-107. (WILEY-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527623693.ch6

Breitmaier E (2008) Sachverzeichnis. In ‘Terpene’. (Ed.^(Eds  pp. 196-210. (WILEY-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527623693.index

CatalÁN TP, Lardies MA and Bozinovic F (2008) Food selection and nutritional ecology of woodlice in Central Chile. Physiological Entomology 33, 89-94. http://dx.doi.org/10.1111/j.1365-3032.2007.00599.x

Chen W-J, Hsiao L-C and Chen KK-Y (2008) Metal desorption from copper(II)/nickel(II)-spiked kaolin as a soil component using plant-derived saponin biosurfactant. Process Biochemistry 43, 488-98. http://www.sciencedirect.com/science/article/pii/S1359511307003200

Clarisa B P-d-S (2008) Vaccines for leishmaniasis in the fore coming 25 years. Vaccine 26, 1709-24. http://www.sciencedirect.com/science/article/pii/S0264410X08000819

De Gregorio E, Tritto E and Rappuoli R (2008) Alum adjuvanticity: Unraveling a century old mystery. European Journal of Immunology 38, 2068-71. http://dx.doi.org/10.1002/eji.200838648

Deng K, Adams MM, Damani P, Livingston PO, Ragupathi G and Gin DY (2008) Synthesis of QS-21-Xylose: Establishment of the Immunopotentiating Activity of Synthetic QS-21 Adjuvant with a Melanoma Vaccine. Angewandte Chemie 120, 6495-8. http://dx.doi.org/10.1002/ange.200801885

Deng K, Adams MM and Gin DY (2008) Synthesis and structure verification of the vaccine adjuvant QS-7-Api. Synthetic access to homogeneous Quillaja saponaria immunostimulants. J Am Chem Soc 130, 5860-1.

Fidan AF and Dundar Y (2008) The effects of Yucca schidigera and Quillaja saponaria on DNA damage, protein oxidation, lipid peroxidation, and some biochemical parameters in streptozotocin-induced diabetic rats. J Diabetes Complications 22, 348-56.

Goel G, Makkar HPS and Becker K (2008) Effects of Sesbania sesban and Carduus pycnocephalus leaves and Fenugreek (Trigonella foenum-graecum L.) seeds and their extracts on partitioning of nutrients from roughage- and concentrate-based feeds to methane. Animal Feed Science and Technology 147, 72-89. http://www.sciencedirect.com/science/article/pii/S0377840107003586

Goel G, Makkar HPS and Becker K (2008) Changes in microbial community structure, methanogenesis and rumen fermentation in response to saponin-rich fractions from different plant materials. Journal of Applied Microbiology 105, 770-7. http://dx.doi.org/10.1111/j.1365-2672.2008.03818.x

Griffing LR (2008) FRET analysis of transmembrane flipping of FM4–64 in plant cells: is FM4–64 a robust marker for endocytosis? Journal of Microscopy 231, 291-8. http://dx.doi.org/10.1111/j.1365-2818.2008.02042.x

Guy B (2008) Adjuvants for Protein- and Carbohydrate-Based Vaccines. In ‘Carbohydrate-Based Vaccines and Immunotherapies’. (Ed.^(Eds  pp. 89-115. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470473283.ch3

Hart KJ, Yáńez-Ruiz DR, Duval SM, McEwan NR and Newbold CJ (2008) Plant extracts to manipulate rumen fermentation. Animal Feed Science and Technology 147, 8-35. http://www.sciencedirect.com/science/article/pii/S0377840107003550

Hassan SM, Moussa EA and Abbott LC (2008) Effects of Quillaja Saponin (Quillaja saponaria) on Early Embryonic Zebrafish (Danio rerio) Development. International Journal of Toxicology 27, 273-8. http://ijt.sagepub.com/cgi/content/abstract/27/3/273

Hendrick RL (2008) Forest Types and Classification. In ‘The Forests Handbook’. (Ed.^(Eds  pp. 23-64. (Blackwell Science Ltd). http://dx.doi.org/10.1002/9780470757062.ch2

Hendriksen CFM (2008) Vaccine Development: Past, Present and Future. In ‘Fighting Infection in the 21st Century’. (Ed.^(Eds  pp. 61-71. (Blackwell Science Ltd). http://dx.doi.org/10.1002/9780470695951.ch4

Lee IA, Popov AM, Kostetskii E, Sanina NM, Mazeika AN and Boguslavskii VM (2008) [Membranotropic effect of some triterpene glycosides possessing immunostimulating properties]. Biofizika 53, 462-9.

Li H, Willingham SB, Ting JPY and Re F (2008) Cutting Edge: Inflammasome Activation by Alum and Alum’s Adjuvant Effect Are Mediated by NLRP3. J. Immunol. 181, 17-21. http://www.jimmunol.org/cgi/content/abstract/181/1/17

Li IA, Popov AM, Tsybul’skii AV, Sanina NM, Kostetskii E, Novikova OD, Portniagina O and Mazeika AV (2008) [Immunostimulatory characteristics of a novel carrier on the basis of cucumarioside A2-2 and monogalactosyldiacylgycerol]. Prikl Biokhim Mikrobiol 44, 694-700.

Lourenco M, Cardozo PW, Calsamiglia S and Fievez V (2008) Effects of saponins, quercetin, eugenol, and cinnamaldehyde on fatty acid biohydrogenation of forage polyunsaturated fatty acids in dual-flow continuous culture fermenters. J Anim Sci 86, 3045-53. http://jas.fass.org/cgi/content/abstract/86/11/3045

Lourenço M, Van Ranst G, Vlaeminck B, De Smet S and Fievez V (2008) Influence of different dietary forages on the fatty acid composition of rumen digesta as well as ruminant meat and milk. Animal Feed Science and Technology 145, 418-37. http://www.sciencedirect.com/science/article/pii/S0377840107002921

Mettens P, Dubois PM, Demoitié M-A, Bayat B, Donner M-N, Bourguignon P, Stewart VA, Heppner Jr DG, Garçon N and Cohen J (2008) Improved T cell responses to Plasmodium falciparum circumsporozoite protein in mice and monkeys induced by a novel formulation of RTS,S vaccine antigen. Vaccine 26, 1072-82. http://www.sciencedirect.com/science/article/pii/S0264410X07014879

Niederhafner P, Reiniš M, Šebestík J and Ježek J (2008) Glycopeptide dendrimers, Part III—a review: Use of glycopeptide dendrimers in immunotherapy and diagnosis of cancer and viral diseases. Journal of Peptide Science 14, 556-87. http://dx.doi.org/10.1002/psc.1011

Oppenheimer SB, Alvarez M and Nnoli J (2008) Carbohydrate-based experimental therapeutics for cancer, HIV/AIDS and other diseases. Acta Histochemica 110, 6-13. http://www.sciencedirect.com/science/article/pii/S0065128107000876

Pen B, Sar C, Mwenya B and Takahashi J (2008) Effects of Quillaja saponaria extract alone or in combination with Yucca schidigera extract on ruminal fermentation and methanogenesis in vitro. Animal Science Journal 79, 193-9. http://dx.doi.org/10.1111/j.1740-0929.2008.00517.x

Ragupathi G, Damani P, Deng K, Adams M, Hang J, George C, Livingston P and Gin D (2008) Preclinical evaluation of fully synthetic saponin adjuvant QS-DG and its isomers as potential adjuvants with cancer vaccines. AACR Meeting Abstracts 2008, 3788-. http://www.aacrmeetingabstracts.org

Ragupathi G, Yeung KS, Leung P-C, Lee M, Lau CBS, Vickers A, Hood C, Deng G, Cheung N-K, Cassileth B and Livingston P (2008) Evaluation of widely consumed botanicals as immunological adjuvants. Vaccine 26, 4860-5. http://www.sciencedirect.com/science/article/pii/S0264410X08008025

Rochfort S, Parker AJ and Dunshea FR (2008) Plant bioactives for ruminant health and productivity. Phytochemistry 69, 299-322. http://www.sciencedirect.com/science/article/pii/S0031942207005250

Singer MD, Robinson PH, Salem AZM and DePeters EJ (2008) Impacts of rumen fluid modified by feeding Yucca schidigera to lactating dairy cows on in vitro gas production of 11 common dairy feedstuffs, as well as animal performance. Animal Feed Science and Technology 146, 242-58. http://www.sciencedirect.com/science/article/pii/S0377840107005469

Stćrk D, Lambert M and W. Jaroszewski J (2008) HPLC-NMR Techniques for Plant Extract Analysis. In ‘Medicinal Plant Biotechnology’. (Ed.^(Eds  pp. 29-48. (Wiley-VCH Verlag GmbH). http://dx.doi.org/10.1002/9783527619771.ch3

Sun J, Song X and Hu S (2008) Ginsenoside Rg1 and Aluminum Hydroxide Synergistically Promote Immune Responses to Ovalbumin in BALB/c Mice. Clin. Vaccine Immunol. 15, 303-7. http://cvi.asm.org/cgi/content/abstract/15/2/303

Sun Y, Li M and Liu J (2008) Haemolytic activities and adjuvant effect of Anemone raddeana saponins (ARS) on the immune responses to ovalbumin in mice. International Immunopharmacology 8, 1095-102. http://www.sciencedirect.com/science/article/pii/S1567576908001124

Vandepapeličre P, Horsmans Y, Moris P, Van Mechelen M, Janssens M, Koutsoukos M, Van Belle P, Clement F, Hanon E, Wettendorff M, Garçon N and Leroux-Roels G (2008) Vaccine Adjuvant Systems containing monophosphoryl lipid A and QS21 induce strong and persistent humoral and T cell responses against hepatitis B surface antigen in healthy adult volunteers. Vaccine 26, 1375-86. http://www.sciencedirect.com/science/article/pii/S0264410X07014867

Wang Y, Lu X and Xu G (2008) Development of a comprehensive two-dimensional hydrophilic interaction chromatography/quadrupole time-of-flight mass spectrometry system and its application in separation and identification of saponins from Quillaja saponaria. Journal of Chromatography A 1181, 51-9. http://www.sciencedirect.com/science/article/pii/S0021967307022248

Wang Y, Lu X and Xu G (2008) Development of a comprehensive two-dimensional hydrophilic interaction chromatography quadrupole time-of-flight mass spectrometry system and its application in separation and identification of saponins from Quillaja saponaria. Journal of chromatography. A. 1181, 51-9. http://dx.doi.org/10.1016/j.chroma.2007.12.034

Xie Y, Pan H, Sun H and Li D (2008) A promising balanced Th1 and Th2 directing immunological adjuvant, saponins from the root of Platycodon grandiflorum. Vaccine 26, 3937-45. http://www.sciencedirect.com/science/article/pii/S0264410X08005501

Xie Y, Ye Y-P, Sun H-X and Li D (2008) Contribution of the glycidic moieties to the haemolytic and adjuvant activity of platycodigenin-type saponins from the root of Platycodon grandiflorum. Vaccine 26, 3452-60. http://www.sciencedirect.com/science/article/pii/S0264410X08004799

Xu G, Wang Y, Zhao X, Chen J, Yin P and Lu X (2008) A new two-dimensional LC–MS/MS-based metabonomics method and its applications in the traditional Chinese medicines and diseases. Journal of Biotechnology 136, Supplement, S26. http://www.sciencedirect.com/science/article/pii/S016816560800312X

Yalinkilic O and Enginar H (2008) Effect of X-Radiation on Lipid Peroxidation and Antioxidant Systems in Rats Treated with Saponin-containing Compounds. Photochemistry and Photobiology 84, 236-42. http://dx.doi.org/10.1111/j.1751-1097.2007.00240.x

Zündorf I, Vollmar AM and Dingermann T (2008) Immunologische Grundlagen des Impfens. Hightech-Training für das Immunsystem. Pharmazie in unserer Zeit 37, 20-7. http://dx.doi.org/10.1002/pauz.200700248

Aguilar JC and Rodríguez EG (2007) Vaccine adjuvants revisited. Vaccine 25, 3752-62. http://www.sciencedirect.com/science/article/pii/S0264410X07001703

Alfaro DM, Silva AVF, Borges SA, Maiorka FA, Vargas S and Santin E (2007) Use of Yucca schidigera Extract in Broiler Diets and Its Effects on Performance Results Obtained with Different Coccidiosis Control Methods. J. Appl. Poult. Res. 16, 248-54. http://japr.fass.org/cgi/content/abstract/16/2/248

Aziz MA, Midha S, Waheed SM and Bhatnagar R (2007) Oral vaccines: new needs, new possibilities. BioEssays 29, 591-604. http://dx.doi.org/10.1002/bies.20580

Baah J, Ivan M, Hristov AN, Koenig KM, Rode LM and McAllister TA (2007) Effects of potential dietary antiprotozoal supplements on rumen fermentation and digestibility in heifers. Animal Feed Science and Technology 137, 126-37. http://www.sciencedirect.com/science/article/pii/S0377840106004986

Barrett AJ and Rezvani K (2007) Translational Mini-Review Series on Vaccines: Peptide vaccines for myeloid leukaemias. Clinical & Experimental Immunology 148, 189-98. http://dx.doi.org/10.1111/j.1365-2249.2007.03383.x

Bauer T, Günther M, Bienzle U, Neuhaus R and Jilg W (2007) Vaccination against hepatitis B in liver transplant recipients: Pilot analysis of cellular immune response shows evidence of HBsAg-specific regulatory T cells. Liver Transplantation 13, 434-42. http://dx.doi.org/10.1002/lt.21061

Bello MA, Hawkins JA and Rudall PJ (2007) Floral Morphology and Development in Quillajaceae and Surianaceae (Fabales), the Species-poor Relatives of Leguminosae and Polygalaceae. Ann. Bot. 100, 1491-505. http://aob.oxfordjournals.org/cgi/content/abstract/100/7/1491

Bermúdez A, Reyes C, Guzmán F, Vanegas M, Rosas J, Amador R, Rodríguez R, Patarroyo MA and Patarroyo ME (2007) Synthetic vaccine update: Applying lessons learned from recent SPf66 malarial vaccine physicochemical, structural and immunological characterization. Vaccine 25, 4487-501. http://www.sciencedirect.com/science/article/pii/S0264410X07003106

Cendron D, Ingoure S, Martino A, Casetti R, Horand F, Romagné F, Sicard H, Fournié J-J and Poccia F (2007) A tuberculosis vaccine based on phosphoantigens and fusion proteins induces distinct γδ and αβ T cell responses in primates. European Journal of Immunology 37, 549-65. http://dx.doi.org/10.1002/eji.200636343

Chapagain BP, Wiesman Z and Tsror L (2007) In vitro study of the antifungal activity of saponin-rich extracts against prevalent phytopathogenic fungi. Industrial Crops and Products 26, 109-15. http://www.sciencedirect.com/science/article/pii/S0926669007000374

Dal Piaz F, De Leo M, Braca A, De Simone F and De Tommasi N (2007) Intramolecular interchain reactions in bidesmosidic glycosides, a new insight into carbohydrate rearrangements induced by electrospray ionisation. Rapid Commun Mass Spectrom 21, 286-96.

Demana PH, Davies NM, Hook S and Rades T (2007) Analysis of Quil A–phospholipid mixtures using drift spectroscopy. International Journal of Pharmaceutics 342, 49-61. http://www.sciencedirect.com/science/article/pii/S0378517307003705

Forest F, Chase MW, Persson C, Crane PR and Hawkins JA (2007) THE ROLE OF BIOTIC AND ABIOTIC FACTORS IN EVOLUTION OF ANT DISPERSAL IN THE MILKWORT FAMILY (POLYGALACEAE). Evolution 61, 1675-94. http://dx.doi.org/10.1111/j.1558-5646.2007.00138.x

Fraser JN, Davis BL, Skjolaas KA, Burkey TE, Dritz SS, Johnson BJ and Minton JE (2007) Effects of feeding Salmonella enterica serovar Typhimurium or serovar Choleraesuis on growth performance and circulating insulin-like growth factor-I, tumor necrosis factor-{alpha}, and interleukin-1{beta} in weaned pigs. J Anim Sci 85, 1161-7. http://jas.fass.org/cgi/content/abstract/85/5/1161

Gamboa-León MR, Aranda-González I, Mut-Martín M, García-Miss MR and Dumonteil E (2007) In vivo and In vitro Control of Leishmania mexicana due to Garlic-induced NO Production. Scandinavian Journal of Immunology 66, 508-14. http://dx.doi.org/10.1111/j.1365-3083.2007.02000.x

Gatlin DM, Barrows FT, Brown P, Dabrowski K, Gaylord TG, Hardy RW, Herman E, Hu G, Krogdahl Ĺ, Nelson R, Overturf K, Rust M, Sealey W, Skonberg D, J Souza E, Stone D, Wilson R and Wurtele E (2007) Expanding the utilization of sustainable plant products in aquafeeds: a review. Aquaculture Research 38, 551-79. http://dx.doi.org/10.1111/j.1365-2109.2007.01704.x

Gilewski TA, Ragupathi G, Dickler M, Powell S, Bhuta S, Panageas K, Koganty RR, Chin-Eng J, Hudis C, Norton L, Houghton AN and Livingston PO (2007) Immunization of High-Risk Breast Cancer Patients with Clustered sTn-KLH Conjugate plus the Immunologic Adjuvant QS-21. Clin. Cancer Res. 13, 2977-85. http://clincancerres.aacrjournals.org/cgi/content/abstract/13/10/2977

Grabensteiner E, Arshad N and Hess M (2007) Differences in the in vitro susceptibility of mono-eukaryotic cultures of Histomonas meleagridis, Tetratrichomonas gallinarum and Blastocystis sp. to natural organic compounds. Parasitol Res 101, 193-9.

Hersey P (2007) Will Vaccines Really Work for Melanoma? In ‘Melanoma’. (Ed.^(Eds  pp. 212-29. (Blackwell Science Ltd). http://dx.doi.org/10.1002/9780470987346.ch16

Hristov AN, Zaman S, VanderPol M, Szasz P, Huber K and Greer D (2007) Effect of a saponin-based surfactant and aging time on ruminal degradability of flaked corn grain dry matter and starch. J Anim Sci 85, 1459-66. http://jas.fass.org/cgi/content/abstract/85/6/1459

Katselis GS, Estrada A, Gorecki DK and Barl B (2007) Adjuvant activities of saponins from the root of Polygala senega L. Can J Physiol Pharmacol 85, 1184-94.

Khajuria A, Gupta A, Malik F, Singh S, Singh J, Gupta BD, Suri KA, Suden P, Srinivas VK, Ella K and Qazi GN (2007) A new vaccine adjuvant (BOS 2000) a potent enhancer mixed Th1/Th2 immune responses in mice immunized with HBsAg. Vaccine 25, 4586-94. http://www.sciencedirect.com/science/article/pii/S0264410X07003866

LÓpez-AbÁn J, Andrade M. do A, Nogal-Ruiz JJ, MartÍnez-FernÁndez AR and Muro A (2007) Immunomodulation of the response to excretory secretory antigens of Fasciola hepatica by Anapsos in Balb C mice and rat alveolar macrophages. Journal of parasitology. 93, 428-32. http://dx.doi.org/10.1645/GE-838R1.1

Lendemans DG, Egert AM, Hook S and Rades T (2007) Cage-like complexes formed by DOTAP, Quil-A and cholesterol. International Journal of Pharmaceutics 332, 192-5. http://www.sciencedirect.com/science/article/pii/S0378517306007800

Littel-van den Hurk SvD, Mapletoft JW, Arsic N and Kovacs-Nolan J (2007) Immunopathology of RSV infection: prospects for developing vaccines without this complication. Reviews in Medical Virology 17, 5-34. http://dx.doi.org/10.1002/rmv.518

Lopez-Aban J, Andrade MA, Nogal-Ruiz JJ, Martinez-Fernande AR and Muro A (2007) Immunomodulation of the response to excretory/secretory antigens of Fasciola hepatica by Anapsos in Balb/C mice and rat alveolar macrophages. J Parasitol 93, 428-32.

Lopez-Aban J, Casanueva P, Nogal J, Arias M, Morrondo P, Diez-Banos P, Hillyer GV, Martinez-Fernande AR and Muro A (2007) Progress in the development of Fasciola hepatica vaccine using recombinant fatty acid binding protein with the adjuvant adaptation system ADAD. Vet Parasitol 145, 287-96.

López-Abán J, Casanueva P, Nogal J, Arias M, Morrondo P, Diez-Bańos P, Hillyer GV, Martínez-Fernández AR and Muro A (2007) Progress in the development of Fasciola hepatica vaccine using recombinant fatty acid binding protein with the adjuvant adaptation system ADAD. Veterinary Parasitology 145, 287-96. http://www.sciencedirect.com/science/article/pii/S0304401706006820

Mbawuike I, Zang Y and Couch RB (2007) Humoral and cell-mediated immune responses of humans to inactivated influenza vaccine with or without QS21 adjuvant. Vaccine 25, 3263-9. http://www.sciencedirect.com/science/article/pii/S0264410X07000382

Meesapyodsuk D, Balsevich J, Reed DW and Covello PS (2007) Saponin Biosynthesis in Saponaria vaccaria. cDNAs Encoding beta-Amyrin Synthase and a Triterpene Carboxylic Acid Glucosyltransferase. Plant Physiology 143, 959-69. http://www.plantphysiol.org/cgi/content/abstract/143/2/959

Muńoz C, Zagal E and Ovalle C (2007) Influence of trees on soil organic matter in Mediterranean agroforestry systems: an example from the ‘Espinal’ of central Chile. European Journal of Soil Science 58, 728-35. http://dx.doi.org/10.1111/j.1365-2389.2006.00858.x

Nico D, Santos FN, Borja-Cabrera GP, Palatnik M and Palatnik de Sousa CB (2007) Assessment of the monoterpene, glycidic and triterpene-moieties’ contributions to the adjuvant function of the CP05 saponin of Calliandra pulcherrima Benth during vaccination against experimental visceral leishmaniasis. Vaccine 25, 649-58. http://www.sciencedirect.com/science/article/pii/S0264410X06009911

Parra LE, Borja-Cabrera GP, Santos FN, Souza LOP, Palatnik-de-Sousa CB and Menz I (2007) Safety trial using the Leishmune® vaccine against canine visceral leishmaniasis in Brazil. Vaccine 25, 2180-6. http://www.sciencedirect.com/science/article/pii/S0264410X06012953

Peiris M, Monteith GR, Roberts-Thomson SJ and Cabot PJ (2007) A model of experimental autoimmune encephalomyelitis (EAE) in C57BL/6 mice for the characterisation of intervention therapies. Journal of Neuroscience Methods 163, 245-54. http://www.sciencedirect.com/science/article/pii/S0165027007001380

Pen B, Takaura K, Yamaguchi S, Asa R and Takahashi J (2007) Effects of Yucca schidigera and Quillaja saponaria with or without β 1–4 galacto-oligosaccharides on ruminal fermentation, methane production and nitrogen utilization in sheep. Animal Feed Science and Technology 138, 75-88. http://www.sciencedirect.com/science/article/pii/S037784010600530X

Pen B, Takaura K, Yamaguchi S, Asa R and Takahashi J (2007) Effects of Yucca schidigera and Quillaja saponaria with or without β 1-4 galacto-oligosaccharides on ruminal fermentation, methane production and nitrogen utilization in sheep. Animal feed science and technology. 22, 1. http://dx.doi.org/10.1016/j.anifeedsci.2006.11.018

Renard V and Leach DR (2007) Perspectives on the development of a therapeutic HER-2 cancer vaccine. Vaccine 25, Supplement 2, B17-B23. http://www.sciencedirect.com/science/article/pii/S0264410X07006524

Roner MR, Sprayberry J, Spinks M and Dhanji S (2007) Antiviral activity obtained from aqueous extracts of the Chilean soapbark tree (Quillaja saponaria Molina). J. Gen. Virol. 88, 275-85. http://vir.sgmjournals.org/cgi/content/abstract/88/1/275

Rosenau J, Hooman N, Hadem J, Rifai K, Bahr MJ, Philipp G, Tillmann HL, Klempnauer J, Strassburg CP and Manns MP (2007) Failure of hepatitis B vaccination with conventional HBsAg vaccine in patients with continuous HBIG prophylaxis after liver transplantation. Liver Transplantation 13, 367-73. http://dx.doi.org/10.1002/lt.21003

Santos FN, Borja-Cabrera GP, Miyashiro LM, Grechi J, Reis AB, Moreira MAB, Martins Filho OA, Luvizotto MCR, Menz I, Pessôa LM, Gonçalves PR, Palatnik M and Palatnik-de-Sousa CB (2007) Immunotherapy against experimental canine visceral leishmaniasis with the saponin enriched-Leishmune® vaccine. Vaccine 25, 6176-90. http://www.sciencedirect.com/science/article/pii/S0264410X07006810

Santoso B, Kilmaskossu A and Sambodo P (2007) Effects of saponin from Biophytum petersianum Klotzsch on ruminal fermentation, microbial protein synthesis and nitrogen utilization in goats. Animal Feed Science and Technology 137, 58-68. http://www.sciencedirect.com/science/article/pii/S0377840106003981

Serabian MA and Huang Y (2007) Preclinical Safety Evaluation of Biopharmaceuticals. In ‘Preclinical Safety Evaluation of Biopharmaceuticals’. (Ed.^(Eds  pp. 713-47. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470292549.ch32

Sun J, Hu S and Song X (2007) Adjuvant effects of protopanaxadiol and protopanaxatriol saponins from ginseng roots on the immune responses to ovalbumin in mice. Vaccine 25, 1114-20. http://www.sciencedirect.com/science/article/pii/S0264410X06010577

Vincken J-P, Heng L, de Groot A and Gruppen H (2007) Saponins, classification and occurrence in the plant kingdom. Phytochemistry 68, 275-97. http://www.sciencedirect.com/science/article/pii/S0031942206006480

Wynn SG and Fougčre BJ (2007) CHAPTER 20 - Veterinary Herbal Medicine: A Systems-Based Approach. In ‘Veterinary Herbal Medicine’. (Ed.^(Eds  pp. 291-409. (Mosby: Saint Louis). http://www.sciencedirect.com/science/article/pii/B978032302998850024X

Xiao C, Rajput ZI, Liu D and Hu S (2007) Enhancement of Serological Immune Responses to Foot-and-Mouth Disease Vaccine by a Supplement Made of Extract of Cochinchina Momordica Seeds. Clin. Vaccine Immunol. 14, 1634-9. http://cvi.asm.org/cgi/content/abstract/14/12/1634

Yang Z, Chen A, Sun H, Ye Y and Fang W (2007) Ginsenoside Rd elicits Th1 and Th2 immune responses to ovalbumin in mice. Vaccine 25, 161-9. http://www.sciencedirect.com/science/article/pii/S0264410X06006797

Yang Z-G, Ye Y-P and Sun H-X (2007) Immunological Adjuvant Effect of Ginsenoside Rh4 from the Roots of Panax notoginseng on Specific Antibody and Cellular Response to Ovalbumin in Mice. Chemistry & Biodiversity 4, 232-40. http://dx.doi.org/10.1002/cbdv.200790028

Yu B, Zhang Y and Tang P (2007) Carbohydrate Chemistry in the Total Synthesis of Saponins. European Journal of Organic Chemistry 2007, 5145-61. http://dx.doi.org/10.1002/ejoc.200700452

Anonymous (2006)   - Arzneipflanzenporträts. In ‘Heilpflanzenpraxis Heute’. (Ed.^(Eds Siegfried B) pp. 49-460. (Urban & Fischer: Munich). http://www.sciencedirect.com/science/article/pii/B9783437572708500093

Anonymous (2006) Index. In ‘Vaccine Adjuvants and Delivery Systems’. (Ed.^(Eds  pp. 445-9. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470134931.index

Anonymous (2006) Chronic Myelogenous Leukemia. In ‘Wiley Handbook of Current and Emerging Drug Therapies’. (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470041000.cedt008

Ameenah G-F (2006) Medicinal plants: Traditions of yesterday and drugs of tomorrow. Molecular Aspects of Medicine 27, 1-93. http://www.sciencedirect.com/science/article/pii/S0098299705000348

Bachran C, Sutherland M, Heisler I, Hebestreit P, Melzig MF and Fuchs H (2006) The Saponin-Mediated Enhanced Uptake of Targeted Saporin-Based Drugs Is Strongly Dependent on the Saponin Structure. Exp Biol Med 231, 412-20. http://ebm.rsmjournals.com/cgi/content/abstract/231/4/412

Balsevich JJ, Bishop GG and Ramirez-Erosa I (2006) Analysis of bisdesmosidic saponins in Saponaria vaccaria L. by HPLC-PAD-MS: identification of new quillaic acid and gypsogenin 3-O-Trisaccharides. Phytochemical Analysis 17, 414-23. http://dx.doi.org/10.1002/pca.943

Breitmaier E (2006) Triterpenes. In ‘Terpenes’. (Ed.^(Eds  pp. 86-108. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527609949.ch6

Breitmaier E (2006) Subject Index. In ‘Terpenes’. (Ed.^(Eds  pp. 197-214. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527609949.indsub

Brunner C, Kanellos T, Meli ML, Sutton DJ, Gisler R, Gomes-Keller MA, Hofmann-Lehmann R and Lutz H (2006) Antibody induction after combined application of an adjuvanted recombinant FeLV vaccine and a multivalent modified live virus vaccine with a chlamydial component. Vaccine 24, 1838-46. http://www.sciencedirect.com/science/article/pii/S0264410X05010674

Cardozo PW, Calsamiglia S, Ferret A and Kamel C (2006) Effects of alfalfa extract, anise, capsicum, and a mixture of cinnamaldehyde and eugenol on ruminal fermentation and protein degradation in beef heifers fed a high-concentrate diet. J Anim Sci 84, 2801-8. http://jas.fass.org/cgi/content/abstract/84/10/2801

Chapagain BP and Wiesman Z (2006) Phyto-saponins as a natural adjuvant for delivery of agromaterials through plant cuticle membranes. J Agric Food Chem 54, 6277-85.

Charlotte Read K (2006) 7 - Immunomodulatory adjuvants from Quillaja saponaria. In ‘Immunopotentiators in Modern Vaccines’. (Ed.^(Eds Virgil EJCS, Dr, PhD and Derek T. O’Hagan BPMP) pp. 109-22. (Academic Press: London). http://www.sciencedirect.com/science/article/pii/B9780120884032500083

Drane D and Pearse MJ (2006) 12 - The ISCOMATRIXTM adjuvant. In ‘Immunopotentiators in Modern Vaccines’. (Ed.^(Eds Virgil EJCS, Dr, PhD and Derek T. O’Hagan BPMP) pp. 191-215. (Academic Press: London). http://www.sciencedirect.com/science/article/pii/B9780120884032500137

Eisenbach C, Sauer P, Mehrabi A, Stremmel W and Encke J (2006) Prevention of hepatitis B virus recurrence after liver transplantation. Clinical Transplantation 20, 111-6. http://dx.doi.org/10.1111/j.1399-0012.2006.00609.x

Elipe MVS (2006) LC-NMR Overview and Pharmaceutical Applications. In ‘HPLC for Pharmaceutical Scientists’. (Ed.^(Eds  pp. 901-36. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470087954.ch20

Fleck JD, Kauffmann C, Spilki F, Lencina CL, Roehe PM and Gosmann G (2006) Adjuvant activity of Quillaja brasiliensis saponins on the immune responses to bovine herpesvirus type 1 in mice. Vaccine 24, 7129-34. http://www.sciencedirect.com/science/article/pii/S0264410X06007985

González-Gómez PL and Vásquez RA (2006) A Field Study of Spatial Memory in Green-Backed Firecrown Hummingbirds (Sephanoides sephaniodes). Ethology 112, 790-5. http://dx.doi.org/10.1111/j.1439-0310.2006.01223.x

Günther M, Neuhaus R, Bauer T, Jilg W, Holtz JA and Bienzle U (2006) Immunization with an adjuvant hepatitis B vaccine in liver transplant recipients: Antibody decline and booster vaccination with conventional vaccine. Liver Transplantation 12, 316-9. http://dx.doi.org/10.1002/lt.20674

Harvey DJ (2006) Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: An update covering the period 1999–2000. Mass Spectrometry Reviews 25, 595-662. http://dx.doi.org/10.1002/mas.20080

Hebestreit P, Weng A, Bachran C, Fuchs H and Melzig MF (2006) Enhancement of cytotoxicity of lectins by Saponinum album. Toxicon 47, 330-5. http://www.sciencedirect.com/science/article/pii/S0041010105004034

Hong-Xiang S (2006) Adjuvant effect of Achyranthes bidentata saponins on specific antibody and cellular response to ovalbumin in mice. Vaccine 24, 3432-9. http://www.sciencedirect.com/science/article/pii/S0264410X06001721

Hong-Xiang S (2006) Haemolytic activities and adjuvant effect of Bupleurum chinense saponins on the immune responses to ovalbumin in mice. Vaccine 24, 1324-31. http://www.sciencedirect.com/science/article/pii/S0264410X05009849

Katayama S and Mine Y (2006) Quillaja saponin can modulate ovalbumin-induced IgE allergic responses through regulation of Th1 Th2 balance in a murine model. Journal of agricultural and food chemistry. 54, 3271-6. http://pubs.acs.org/journals/jafcau/index.html

Kim YJ, Wang P, Navarro-Villalobo M, Rohde BD, Derryberry J and Gin DY (2006) Synthetic studies of complex immunostimulants from Quillaja saponaria: synthesis of the potent clinical immunoadjuvant QS-21Aapi. J Am Chem Soc 128, 11906-15.

Kukhetpitakwong R, Hahnvajanawong C, Homchampa P, Leelavatcharamas V, Satra J and Khunkitti W (2006) Immunological adjuvant activities of saponin extracts from the pods of Acacia concinna. International Immunopharmacology 6, 1729-35. http://www.sciencedirect.com/science/article/pii/S1567576906002499

Li R, Zhou Y, Wu Z and Ding L (2006) ESI-QqTOF-MS/MS and APCI-IT-MS/MS analysis of steroid saponins from the rhizomes of Dioscorea panthaica. Journal of Mass Spectrometry 41, 1-22. http://dx.doi.org/10.1002/jms.988

Lindblad EB (2006) Safety Evaluation of Vaccine Adjuvants. In ‘Vaccine Adjuvants and Delivery Systems’. (Ed.^(Eds  pp. 421-44. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470134931.ch18

Livingston PO, Hood C and Ragupathi G (2006) Botanicals as immunological adjuvants and immunomodulators. AACR Meeting Abstracts 2006, 1306-c-7. http://www.aacrmeetingabstracts.org/cgi/content/abstract/2006/1/1306-c

Maria Teresa DM (2006) Mucosal delivery of vaccine antigens and its advantages in pediatrics. Advanced Drug Delivery Reviews 58, 52-67. http://www.sciencedirect.com/science/article/pii/S0169409X06000068

Morein B, Hu K, Lövgren K and D’Hondt E (2006) New ISCOMs Meet Unsettled Vaccine Demands. In ‘Vaccine Adjuvants and Delivery Systems’. (Ed.^(Eds  pp. 191-222. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470134931.ch9

Myschik J, Lendemans DG, McBurney WT, Demana PH, Hook S and Rades T (2006) On the preparation, microscopic investigation and application of ISCOMs. Micron 37, 724-34. http://www.sciencedirect.com/science/article/pii/S0968432806000448

Nikolai P (2006) Novel human polysaccharide adjuvants with dual Th1 and Th2 potentiating activity. Vaccine 24, Supplement 2, S26-S9. http://www.sciencedirect.com/science/article/pii/S0264410X05001581

Oliveira-Freitas E, Casas CP, Borja-Cabrera GP, Santos FN, Nico D, Souza LO, Tinoco LW, da Silva BP, Palatnik M, Parente JP and Palatnik-de-Sousa CB (2006) Acylated and deacylated saponins of Quillaja saponaria mixture as adjuvants for the FML-vaccine against visceral leishmaniasis. Vaccine 24, 3909-20.

Oliveira-Freitas E, Casas CP, Borja-Cabrera GP, Santos FN, Nico D, Souza LOP, Tinoco LW, da Silva BP, Palatnik M, Parente JP and Palatnik-de-Sousa CB (2006) Acylated and deacylated saponins of Quillaja saponaria mixture as adjuvants for the FML-vaccine against visceral leishmaniasis. Vaccine 24, 3909-20. http://www.sciencedirect.com/science/article/pii/S0264410X06002088

Olszewska W and Openshaw PJM (2006) Mucosal Vaccination. In ‘Encyclopedia of Molecular Cell Biology and Molecular Medicine’. (Ed.^(Eds  pp. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/3527600906.mcb.200400152

Passos Eleutério MI, Schimmel J, Ritter G, do Céu Costa M and Schmidt RR (2006) Synthesis of Saponins with Allobetulin and Glycyrrhetic Acid as Aglycones. European Journal of Organic Chemistry 2006, 5293-304. http://dx.doi.org/10.1002/ejoc.200600565

Pen B, Sar C, Mwenya B, Kuwaki K, Morikawa R and Takahashi J (2006) Effects of Yucca schidigera and Quillaja saponaria extracts on in vitro ruminal fermentation and methane emission. Animal Feed Science and Technology 129, 175-86. http://www.sciencedirect.com/science/article/pii/S0377840106000101

Pham HL, Ross BP, McGeary RP, Shaw PN, Hewavitharana AK and Davies NM (2006) Saponins from Quillaja saponaria Molina: isolation, characterization and ability to form immuno stimulatory complexes (ISCOMs). Curr Drug Deliv 3, 389-97.

Qin F, Ye Y-P and Sun H-X (2006) Haemolytic Activity and Adjuvant Effect of Notoginsenoside K from the Roots of Panax notoginseng. Chemistry & Biodiversity 3, 1144-52. http://dx.doi.org/10.1002/cbdv.200690116

Rosenau J, Hooman N, Rifai K, Solga T, Tillmann HL, Grzegowski E, Nashan B, Klempnauer J, Strassburg CP, Wedemeyer H and Manns MP (2006) Hepatitis B virus immunization with an adjuvant containing vaccine after liver transplantation for hepatitis B-related disease: failure of humoral and cellular immune response. Transplant International 19, 828-33. http://dx.doi.org/10.1111/j.1432-2277.2006.00374.x

Sandberg FB, Emmans GC and Kyriazakis I (2006) A model for predicting feed intake of growing animals during exposure to pathogens. J Anim Sci 84, 1552-66. http://jas.fass.org/cgi/content/abstract/84/6/1552

Saraiva EM, Barbosa AdF, Santos FN, Borja-Cabrera GP, Nico D, Souza LOP, Mendes-Aguiar CdO, de Souza EP, Fampa P, Parra LE, Menz I, Jr JGD, de Oliveira SM and Palatnik-de-Sousa CB (2006) The FML-vaccine (Leishmune®) against canine visceral leishmaniasis: A transmission blocking vaccine. Vaccine 24, 2423-31. http://www.sciencedirect.com/science/article/pii/S0264410X0501217X

Schimmel J, Passos Eleutério MI, Ritter G and Schmidt RR (2006) Synthesis of Saponins with Cholestanol, Cholesterol, and Friedelanol as Aglycones. European Journal of Organic Chemistry 2006, 1701-21. http://dx.doi.org/10.1002/ejoc.200500816

Simon JK and Edelman R (2006) 18 - Clinical evaluation of adjuvants. In ‘Immunopotentiators in Modern Vaccines’. (Ed.^(Eds Virgil EJCS, Dr, PhD and Derek T. O’Hagan BPMP) pp. 319-42. (Academic Press: London). http://www.sciencedirect.com/science/article/pii/B9780120884032500198

Stoute JA, Heppner DGJ, Mason CJ, Siangla J, Opollo MO, Kester KE, Vigneron L, Voss G, Walter MJ, Tornieporth N, Cohen JD and Ballou WR (2006) PHASE 1 SAFETY AND IMMUNOGENICITY TRIAL OF MALARIA VACCINE RTS,S/AS02A IN ADULTS IN A HYPERENDEMIC REGION OF WESTERN KENYA. Am J Trop Med Hyg 75, 166-70. http://www.ajtmh.org/cgi/content/abstract/75/1/166

Sun H, Yang Z and Ye Y (2006) Structure and biological activity of protopanaxatriol-type saponins from the roots of Panax notoginseng. International Immunopharmacology 6, 14-25. http://www.sciencedirect.com/science/article/pii/S1567576905002031

Sun H-X, Chen Y and Ye Y (2006) Ginsenoside Re and Notoginsenoside R1: Immunologic Adjuvants with Low Haemolytic Effect. Chemistry & Biodiversity 3, 718-26. http://dx.doi.org/10.1002/cbdv.200690074

Sun H-X and Pan H-J (2006) Immunological adjuvant effect of Glycyrrhiza uralensis saponins on the immune responses to ovalbumin in mice. Vaccine 24, 1914-20. http://www.sciencedirect.com/science/article/pii/S0264410X05010960

Tsenova L, Harbacheuski R, Moreira AL, Ellison E, Dalemans W, Alderson MR, Mathema B, Reed SG, Skeiky YAW and Kaplan G (2006) Evaluation of the Mtb72F Polyprotein Vaccine in a Rabbit Model of Tuberculous Meningitis. Infect. Immun. 74, 2392-401. http://iai.asm.org/cgi/content/abstract/74/4/2392

Vajdy M (2006) Mucosal Adjuvants and Delivery Systems. In ‘Vaccine Adjuvants and Delivery Systems’. (Ed.^(Eds  pp. 295-326. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470134931.ch13

Zhang Z, Li S, Zhang S and Gorenstein D (2006) Triterpenoid saponins from the fruits of Aesculus pavia. Phytochemistry 67, 784-94. http://www.sciencedirect.com/science/article/pii/S0031942206000380

Anonymous (2005) Current literature in mass spectrometry. Journal of Mass Spectrometry 40, 550-61. http://dx.doi.org/10.1002/jms.805

Anonymous (2005) Current Awareness in Phytochemical Analysis. Phytochemical Analysis 16, 231-8. http://dx.doi.org/10.1002/pca.795

Badano EI, Cavieres LA, Molina-Montenegro MA and Quiroz CL (2005) Slope aspect influences plant association patterns in the Mediterranean matorral of central Chile. Journal of Arid Environments 62, 93-108. http://www.sciencedirect.com/science/article/pii/S0140196304002344

Baral R, Mandal I and Chattopadhyay U (2005) Immunostimulatory neem leaf preparation acts as an adjuvant to enhance the efficacy of poorly immunogenic B16 melanoma surface antigen vaccine. International Immunopharmacology 5, 1343-52. http://www.sciencedirect.com/science/article/pii/S1567576905000809

Celis-Diez JL and Bustamante RO (2005) Frequency-dependent seed size selection on Cryptocarya alba (Mol.) Looser (Lauraceae): testing the effect of background. Biological Journal of the Linnean Society 84, 137-42. http://dx.doi.org/10.1111/j.1095-8312.2005.00420.x

Cheeke PR and Otero R (2005) Yucca, quillaja may have role in animal nutrition. Feedstuffs. 77, 11-4.

E.M A (2005) Effect of Yucca schidigera saponin on the nutritive value of urea-ammoniated maize stover and its feeding value when supplemented with forage legume (Calliandra calothyrsus) for goats. Small Ruminant Research 56, 95-102. http://www.sciencedirect.com/science/article/pii/S092144880400118X

Elson CO and Dertzbaugh MT (2005) Chapter 54 - Mucosal Adjuvants. In ‘Mucosal Immunology (Third Edition)’. (Ed.^(Eds Jiri M, Michael EL, Jerry RM, John B, Lloyd M, Warren StroberA2 - Jiri Mestecky MELJRMJBLM and Warren S) pp. 967-86. (Academic Press: Burlington). http://www.sciencedirect.com/science/article/pii/B9780124915435500589

Fajardo A and Alaback P (2005) Effects of natural and human disturbances on the dynamics and spatial structure of Nothofagus glauca in south-central Chile. Journal of Biogeography 32, 1811-25. http://dx.doi.org/10.1111/j.1365-2699.2005.01331.x

Francis G, Makkar HPS and Becker K (2005) Quillaja saponins—a natural growth promoter for fish. Animal Feed Science and Technology 121, 147-57. http://www.sciencedirect.com/science/article/pii/S0377840105000684

Francis G, Makkar HPS and Becker K (2005) Quillaja saponins—a natural growth promoter for fish. Animal feed science and technology. 121, 147-57.

Harinder P.S M (2005) In vitro gas methods for evaluation of feeds containing phytochemicals. Animal Feed Science and Technology 123-124, Part 1, 291-302. http://www.sciencedirect.com/science/article/pii/S0377840105002610

Hauer AD, Uyttenhove C, de Vos P, Stroobant V, Renauld JC, van Berkel TJC, van Snick J and Kuiper J (2005) Blockade of Interleukin-12 Function by Protein Vaccination Attenuates Atherosclerosis. Circulation 112, 1054-62. http://circ.ahajournals.org/cgi/content/abstract/112/7/1054

Holten-Andersen L, Doherty TM, Korsholm KS and Andersen P (2005) Final Report of the Safety Assessment of Acacia Catechu Gum, Acacia Concinna Fruit Extract, Acacia Dealbata Leaf Extract, Acacia Dealbata Leaf Wax, Acacia Decurrens Extract, Acacia Farnesiana Extract, Acacia Farnesiana Flower Wax, Acacia Farnesiana Gum, Acacia Senegal Extract, Acacia Senegal Gum, and Acacia Senegal Gum Extract

Combination of the Cationic Surfactant Dimethyl Dioctadecyl Ammonium Bromide and Synthetic Mycobacterial Cord Factor as an Efficient Adjuvant for Tuberculosis Subunit Vaccines. International Journal of Toxicology 24, 75-118. http://ijt.sagepub.com/cgi/content/abstract/24/3_suppl/75

http://iai.asm.org/cgi/content/abstract/72/3/1608

Hu KF, Regner M, Siegrist CA, Lambert P, Chen M, Bengtsson KL and Morein B (2005) The immunomodulating properties of human respiratory syncytial virus and immunostimulating complexes containing Quillaja saponin components QH-A, QH-C and ISCOPREP 703. FEMS immunology and medical microbiology. 43, 269-76.

Hu K-F, Regner M, Siegrist C-A, Lambert P, Chen M, Bengtsson KL and Morein B (2005) The immunomodulating properties of human respiratory syncytial virus and immunostimulating complexes containing Quillaja saponin components QH-A, QH-C and ISCOPREPTM703. FEMS Immunology and Medical Microbiology 43, 269-76. http://www.sciencedirect.com/science/article/pii/S0928824404001890

Ilsley SE and Miller HM (2005) Effect of dietary supplementation of sows with quillaja saponins during gestation on colostrum composition and performance of piglets suckled. Animal science : an international journal of fundamental and applied research. 80, 2.

Ilsley SE, Miller HM and Kamel C (2005) Effects of dietary quillaja saponin and curcumin on the performance and immune status of weaned piglets. J Anim Sci 83, 82-8. http://jas.fass.org/cgi/content/abstract/83/1/82

Johnson BJ, Dritz SS, Skjolaas-Wilson KA, Burkey TE and Minton JE (2005) Interactive responses in gut immunity, and systemic and local changes in the insulin-like growth factor system in nursery pigs in response to Salmonella enterica serovar Typhimurium. J Anim Sci 83, E48-56. http://jas.fass.org/cgi/content/abstract/83/13_suppl/E48

Lendemans DG, Myschik J, Hook S and Rades T (2005) Immuno-stimulating complexes prepared by ethanol injection. Journal of Pharmacy and Pharmacology 57, 729-33. http://dx.doi.org/10.1211/0022357056280

Lendemans DG, Myschik J, Hook S and Rades T (2005) Cationic cage-like complexes formed by DC-cholesterol, Quil-A, and phospholipid. Journal of Pharmaceutical Sciences 94, 1794-807. http://dx.doi.org/10.1002/jps.20394

Levavi-Sivan B, Hedvat R, Kanias T, Francis G, Becker K and Kerem Z (2005) Exposure of tilapia pituitary cells to saponins: Insight into their mechanism of action. Comparative Biochemistry and Physiology Part C: Toxicology &amp; Pharmacology 140, 79-86. http://www.sciencedirect.com/science/article/pii/S1532045605000037

Marciani DJ, Ptak RG, Voss TG, Reynolds RC, Pathak AK, Chamblin TL, Scholl DR and May RD (2005) Corrigendum to “Degradation of Quillaja saponaria Molina saponins: Loss of the protective effects of a herpes simplex virus 1 subunit vaccine” [International Immunopharmacology 2/12 (2002) 1703–1711]. International Immunopharmacology 5, 1658. http://www.sciencedirect.com/science/article/pii/S1567576905001293

Melzig MF, Hebestreit P, Gaidi G and Lacaille-Dubois MA (2005) Structure-activity-relationship of saponins to enhance toxic effects of agrostin. Planta medica. 71, 1088-90.

Meraldi V, Romero JF, Kensil C and Corradin G (2005) A strong CD8+ T cell response is elicited using the synthetic polypeptide from the C-terminus of the circumsporozoite protein of Plasmodium berghei together with the adjuvant QS-21: quantitative and phenotypic comparison with the vaccine model of irradiated sporozoites. Vaccine 23, 2801-12. http://www.sciencedirect.com/science/article/pii/S0264410X04008953

Michalek SM, O’Hagan DT, Childers NK, Osterhaus ADME and Rimmelzwaan GF (2005) Chapter 55 - Antigen Delivery Systems I: Nonliving Microparticles, Liposomes, and Immune Stimulating Complexes (ISCOMs). In ‘Mucosal Immunology (Third Edition)’. (Ed.^(Eds Jiri M, Michael EL, Jerry RM, John B, Lloyd M, Warren StroberA2 - Jiri Mestecky MELJRMJBLM and Warren S) pp. 987-1007. (Academic Press: Burlington). http://www.sciencedirect.com/science/article/pii/B9780124915435500590

Neto BB, Scarminio IS and Bruns RE (2005) Chapter 6 Exploring the response surface. In ‘Data Handling in Science and Technology’. (Ed.^(Eds R.E. Bruns ISS and Neto BdB) pp. 245-312. (Elsevier). http://www.sciencedirect.com/science/article/pii/S0922348705250062

Park J-Y, Plahar MA, Hung Y-C, McWatters KH and Eun J-B (2005) Effect of saponins on the foam/flow properties of paste and physical characteristics of akara made from decorticated black-eyed cowpeas. Journal of the Science of Food and Agriculture 85, 1845-51. http://dx.doi.org/10.1002/jsfa.2192

Pinczewski J, Zhao J, Malkevitch N, Patterson LJ, Aldrich K, Alvord WG and Robert-Guroff M (2005) Enhanced immunity and protective efficacy against SIVmac251 intrarectal challenge following ad-SIV priming by multiple mucosal routes and gp120 boosting in MPL-SE. Viral Immunol 18, 236-43.

Poland GA and Poterucha JJ (2005) Hepatitis B immunization after liver transplantation: What is the answer? Liver Transplantation 11, 1181-3. http://dx.doi.org/10.1002/lt.20538

Poon B, Safrit JT, McClure H, Kitchen C, Hsu JF, Gudeman V, Petropoulos C, Wrin T, Chen ISY and Grovit-Ferbas K (2005) Induction of Humoral Immune Responses following Vaccination with Envelope-Containing, Formaldehyde-Treated, Thermally Inactivated Human Immunodeficiency Virus Type 1. J. Virol. 79, 4927-35. http://jvi.asm.org/cgi/content/abstract/79/8/4927

Regodón S, Martín-Palomino P, Fernández-Montesinos R, Herrera JL, Carrascosa-Salmoral MP, Píriz S, Vadillo S, Guerrero JM and Pozo D (2005) The use of melatonin as a vaccine agent. Vaccine 23, 5321-7. http://www.sciencedirect.com/science/article/pii/S0264410X05006407

San Martin R and Magunacelaya JC (2005) Control of plant-parasitic nematodes with extracts of Quillaja saponaria. Nematology : international journal of fundamental and applied nematological research. 7, 4.

San Martin RM, Otero AF and Cruz A (2005) Use of quillaja saponins (Quillaja saponaria Molina) to control acid mist in copper electrowinning processes: Part 2: pilot plant and industrial scale evaluation. Hydrometallurgy 77, 171-81. http://www.sciencedirect.com/science/article/pii/S0304386X04001938

San Martin RM, Otero AF, Figueroa M, Escobar V and Cruz A (2005) Use of quillaja saponins (Quillaja saponaria Molina) to control acid mist in copper electrowinning processes: Part 1. Laboratory scale evaluation. Hydrometallurgy 77, 163-70. http://www.sciencedirect.com/science/article/pii/S0304386X04002336

Schöll I, Boltz-Nitulescu G and Jensen-Jarolim E (2005) Review of novel particulate antigen delivery systems with special focus on treatment of type I allergy. Journal of Controlled Release 104, 1-27. http://www.sciencedirect.com/science/article/pii/S0168365905000106

Schwegler C, Dorn-Beineke A, Nittka S, Stocking C and Neumaier M (2005) Monoclonal Anti-idiotype Antibody 6G6.C4 Fused to GM-CSF Is Capable of Breaking Tolerance to Carcinoembryonic Antigen (CEA) in CEA-Transgenic Mice. Cancer Res. 65, 1925-33. http://cancerres.aacrjournals.org/cgi/content/abstract/65/5/1925

Silva BP, Soares JB, Souza EP, Palatnik M, Sousa CB and Parente JP (2005) Pulcherrimasaponin, from the leaves of Calliandra pulcherrima, as adjuvant for immunization in the murine model of visceral leishmaniasis. Vaccine 23, 1061-71.

Silva BPd, Soares JBRC, Souza EPd, Palatnik M, Sousa CBPd and Parente JP (2005) Pulcherrimasaponin, from the leaves of Calliandra pulcherrima, as adjuvant for immunization in the murine model of visceral leishmaniasis. Vaccine 23, 1061-71. http://www.sciencedirect.com/science/article/pii/S0264410X04006309

Slovin SF, Ragupathi G, Fernandez C, Jefferson MP, Diani M, Wilton AS, Powell S, Spassova M, Reis C, Clausen H, Danishefsky S, Livingston P and Scher HI (2005) A bivalent conjugate vaccine in the treatment of biochemically relapsed prostate cancer: a study of glycosylated MUC-2-KLH and Globo H-KLH conjugate vaccines given with the new semi-synthetic saponin immunological adjuvant GPI-0100 OR QS-21. Vaccine 23, 3114-22. http://www.sciencedirect.com/science/article/pii/S0264410X05001027

Sun H and Zheng Q (2005) Haemolytic activities and adjuvant effect of Gynostemma pentaphyllum saponins on the immune responses to ovalbumin in mice. Phytotherapy Research 19, 895-900. http://dx.doi.org/10.1002/ptr.1754

Terrault N, Roche B and Samuel D (2005) Management of the hepatitis B virus in the liver transplantation setting: A European and an American perspective. Liver Transplantation 11, 716-32. http://dx.doi.org/10.1002/lt.20492

Vandepapeličre P, Rehermann B, Koutsoukos M, Moris P, Garçon N, Wettendorff M and Leroux-Roels G (2005) Potent enhancement of cellular and humoral immune responses against recombinant hepatitis B antigens using AS02A adjuvant in healthy adults. Vaccine 23, 2591-601. http://www.sciencedirect.com/science/article/pii/S0264410X04008758

Wikman M, Friedman M, Pinitkiatisakul S, Hemphill A, Lövgren-Bengtsson K, Lundén A and Stĺhl S (2005) Applying biotin–streptavidin binding for iscom (immunostimulating complex) association of recombinant immunogens. Biotechnology and Applied Biochemistry 41, 163-74. http://dx.doi.org/10.1042/BA20040060

Wisniewski T and Frangione B (2005) Immunological and Anti-Chaperone Therapeutic Approaches for Alzheimer Disease. Brain Pathology 15, 72-7. http://dx.doi.org/10.1111/j.1750-3639.2005.tb00102.x

Yang Z-G, Sun H-X and Fang W-H (2005) Haemolytic activities and adjuvant effect of Astragalus membranaceus saponins (AMS) on the immune responses to ovalbumin in mice. Vaccine 23, 5196-203. http://www.sciencedirect.com/science/article/pii/S0264410X05006043

Atanackovic D, Altorki NK, Stockert E, Williamson B, Jungbluth AA, Ritter E, Santiago D, Ferrara CA, Matsuo M, Selvakumar A, Dupont B, Chen Y-T, Hoffman EW, Ritter G, Old LJ and Gnjatic S (2004) Vaccine-Induced CD4+ T Cell Responses to MAGE-3 Protein in Lung Cancer Patients. J. Immunol. 172, 3289-96. http://www.jimmunol.org/cgi/content/abstract/172/5/3289

Becerra PI, Celis-Diez JL and Bustamante RO (2004) Effects of leaf litter and precipitation on germination and seedling survival of the endangered tree Beilschmiedia miersii. Applied Vegetation Science 7, 253-7. http://dx.doi.org/10.1111/j.1654-109X.2004.tb00617.x

Broberg S, Nord LI and Kenne L (2004) Oligosaccharide sequences in Quillaja saponins by electrospray ionization ion trap multiple-stage mass spectrometry. J Mass Spectrom 39, 691-701.

Broytman O and Malter JS (2004) Anti-Aβ: The good, the bad, and the unforeseen. Journal of Neuroscience Research 75, 301-6. http://dx.doi.org/10.1002/jnr.10876

Burkey TE, Dritz SS, Nietfeld JC, Johnson BJ and Minton JE (2004) Effect of dietary mannanoligosaccharide and sodium chlorate on the growth performance, acute-phase response, and bacterial shedding of weaned pigs challenged with Salmonella entericaserotype Typhimurium. J Anim Sci 82, 397-404. http://jas.fass.org/cgi/content/abstract/82/2/397

Cathcart K, Pinilla-Ibarz J, Korontsvit T, Schwartz J, Zakhaleva V, Papadopoulos EB and Scheinberg DA (2004) A multivalent bcr-abl fusion peptide vaccination trial in patients with chronic myeloid leukemia. Blood 103, 1037-42. http://bloodjournal.hematologylibrary.org/cgi/content/abstract/103/3/1037

Celis-Diez JL, Bustamante RO and VÁSquez RA (2004) Assessing frequency-dependent seed size selection: a field experiment. Biological Journal of the Linnean Society 81, 307-12. http://dx.doi.org/10.1111/j.1095-8312.2003.00287.x

Chapman PB, Wu D, Ragupathi G, Lu S, Williams L, Hwu W-J, Johnson D and Livingston PO (2004) Sequential Immunization of Melanoma Patients with GD3 Ganglioside Vaccine and Anti-Idiotypic Monoclonal Antibody That Mimics GD3 Ganglioside. Clin. Cancer Res. 10, 4717-23. http://clincancerres.aacrjournals.org/cgi/content/abstract/10/14/4717

Cheng CY, Urbani MD, Miovski P, Kittelty D, Otero AF and San Martı́n RM (2004) Evaluation of saponins as acid mist suppressants in zinc electrowinning. Hydrometallurgy 73, 133-45. http://www.sciencedirect.com/science/article/pii/S0304386X03002366

Cox RA and Magee DM (2004) Coccidioidomycosis: Host Response and Vaccine Development. Clin. Microbiol. Rev. 17, 804-39. http://cmr.asm.org/cgi/content/abstract/17/4/804

de Leder Kremer RM and Gallo-Rodriguez C (2004) NATURALLY OCCURRING MONOSACCHARIDES: PROPERTIES AND SYNTHESIS. In ‘Advances in Carbohydrate Chemistry and Biochemistry’. (Ed.^(Eds  pp. 9-67. (Academic Press). http://www.sciencedirect.com/science/article/pii/S0065231804590029

Demana PH, Davies NM, Vosgerau U and Rades T (2004) Pseudo-ternary phase diagrams of aqueous mixtures of Quil A, cholesterol and phospholipid prepared by the lipid-film hydration method. International Journal of Pharmaceutics 270, 229-39. http://www.sciencedirect.com/science/article/pii/S0378517303005738

Dembitsky VM (2004) Chemistry and Biod iversity of the Biologically Active Natural Glycosides. Chemistry & Biodiversity 1, 673-781. http://dx.doi.org/10.1002/cbdv.200490060

Dubroeucq D and Livenais P (2004) Land cover and land use changes in relation to social evolution—a case study from Northern Chile. Journal of Arid Environments 56, 193-211. http://www.sciencedirect.com/science/article/pii/S0140196303000429

Eryavuz A and Dehority BA (2004) Effect of Yucca schidigera extract on the concentration of rumen microorganisms in sheep. Animal Feed Science and Technology 117, 215-22. http://www.sciencedirect.com/science/article/pii/S0377840104001713

Figueroa JA, Teillier S and Jaksic FM (2004) Composition, size and dynamics of the seed bank in a mediterranean shrubland of Chile. Austral Ecology 29, 574-84. http://dx.doi.org/10.1111/j.1442-9993.2004.01392.x

GonzÁLez AM, Nguyen TV, Azevedo MSP, Jeong K, Agarib F, Iosef C, Chang K, Lovgren-Bengtsson K, Morein B and Saif LJ (2004) Antibody responses to human rotavirus (HRV) in gnotobiotic pigs following a new prime/boost vaccine strategy using oral attenuated HRV priming and intranasal VP2/6 rotavirus-like particle (VLP) boosting with ISCOM. Clinical & Experimental Immunology 135, 361-72. http://dx.doi.org/10.1111/j.1365-2249.2004.02395.x

Hristov AN, Grandeen KL, Ropp JK and Greer D (2004) Effect of Yucca schidigera-based surfactant on ammonia utilization in vitro, and in situ degradability of corn grain. Animal Feed Science and Technology 115, 341-55. http://www.sciencedirect.com/science/article/pii/S0377840104000719

Israf DA, Lajis NH, Somchit MN and Sulaiman MR (2004) Enhancement of ovalbumin-specific IgA responses via oral boosting with antigen co-administered with an aqueous Solanum torvum extract. Life Sciences 75, 397-406. http://www.sciencedirect.com/science/article/pii/S0024320504002681

Jenkins NL, Turner JL, Dritz SS, Durham SK and Minton JE (2004) Changes in circulating insulin-like growth factor-I, insulin-like growth factor binding proteins, and leptin in weaned pigs infected with Salmonella enterica serovar Typhimurium. Domestic Animal Endocrinology 26, 49-60. http://www.sciencedirect.com/science/article/pii/S073972400300095X

Jin H, Li Y, Ma Z, Zhang F, Xie Q, Gu D and Wang B (2004) Effect of chemical adjuvants on DNA vaccination. Vaccine 22, 2925-35. http://www.sciencedirect.com/science/article/pii/S0264410X0400074X

Kirk DD, Rempel R, Pinkhasov J and Walmsley AM (2004) Application of Quillaja saponaria extracts as oral adjuvants for plant-made vaccines. Expert Opin Biol Ther 4, 947-58.

Kite GC, Howes MJ and Simmonds MS (2004) Metabolomic analysis of saponins in crude extracts of Quillaja saponaria by liquid chromatography/mass spectrometry for product authentication. Rapid Commun Mass Spectrom 18, 2859-70.

Kite GC, Howes M-JR and Simmonds MSJ (2004) Metabolomic analysis of saponins in crude extracts of Quillaja saponaria by liquid chromatography/mass spectrometry for product authentication. Rapid Communications in Mass Spectrometry 18, 2859-70. http://dx.doi.org/10.1002/rcm.1698

Krug LM, Ragupathi G, Ng KK, Hood C, Jennings HJ, Guo Z, Kris MG, Miller V, Pizzo B, Tyson L, Baez V and Livingston PO (2004) Vaccination of Small Cell Lung Cancer Patients with Polysialic Acid or N-Propionylated Polysialic Acid Conjugated to Keyhole Limpet Hemocyanin. Clin. Cancer Res. 10, 916-23. http://clincancerres.aacrjournals.org/cgi/content/abstract/10/3/916

Lambert SL, Okada CY and Levy R (2004) TCR Vaccines against a Murine T Cell Lymphoma: A Primary Role for Antibodies of the IgG2c Class in Tumor Protection. J. Immunol. 172, 929-36. http://www.jimmunol.org/cgi/content/abstract/172/2/929

Lee M K (2004) Vaccine therapy for small cell lung cancer. Seminars in Oncology 31, Supplement 1, 112-6. http://www.sciencedirect.com/science/article/pii/S0093775403006602

Magi M, Garcia L, Vandenbranden M, Palmantier R and Jacquet A (2004) Heat denaturation affects the ProDer p 1 IgE reactivity and downregulates the development of the specific allergic response. Journal of Allergy and Clinical Immunology 114, 545-52. http://www.sciencedirect.com/science/article/pii/S0091674904013223

Martinez-Fernande AR, Nogal-Ruiz JJ, Lopez-Aban J, Ramajo V, Oleaga A, Manga-Gonzalez Y, Hillyer GV and Muro A (2004) Vaccination of mice and sheep with Fh12 FABP from Fasciola hepatica using the new adjuvant/immunomodulator system ADAD. Vet Parasitol 126, 287-98.

Martínez-Fernández AR, Nogal-Ruiz JJ, López-Abán J, Ramajo V, Oleaga A, Manga-González Y, Hillyer GV and Muro A (2004) Vaccination of mice and sheep with Fh12 FABP from Fasciola hepatica using the new adjuvant/immunomodulator system ADAD. Veterinary Parasitology 126, 287-98. http://www.sciencedirect.com/science/article/pii/S0304401704003772

Morein B, Hu K-F and Abusugra I (2004) Current status and potential application of ISCOMs in veterinary medicine. Advanced Drug Delivery Reviews 56, 1367-82. http://www.sciencedirect.com/science/article/pii/S0169409X04000675

Návar J, Méndez E, Nájera A, Graciano J, Dale V and Parresol B (2004) Biomass equations for shrub species of Tamaulipan thornscrub of North-eastern Mexico. Journal of Arid Environments 59, 657-74. http://www.sciencedirect.com/science/article/pii/S0140196304000485

Oda K, Sato Y, Katayama S, Ito A and Ohgitani T (2004) Separation and characterization of adjuvant oligosaccharide oleate ester derived from product mixture of mannitol-oleic acid esterification. Vaccine 22, 2812-21. http://www.sciencedirect.com/science/article/pii/S0264410X04000301

Palatnik de Sousa CB, Santos WR, Casas CP, Paraguai de Souza E, Tinoco LW, da Silva BP, Palatnik M and Parente JP (2004) Protective vaccination against murine visceral leishmaniasis using aldehyde-containing Quillaja saponaria sapogenins. Vaccine 22, 2470-9. http://www.sciencedirect.com/science/article/pii/S0264410X04002580

Rimola A and Sánchez-Fueyo A (2004) Hepatitis B vaccination after liver transplantation as a strategy to discontinue prophylaxis with hepatitis B immune globulin. Journal of Hepatology 40, 722-4. http://www.sciencedirect.com/science/article/pii/S0168827804000728

Roche B and Samuel D (2004) Evolving strategies to prevent HBV recurrence. Liver Transplantation 10, S74-S85. http://dx.doi.org/10.1002/lt.20258

Skeiky YAW, Alderson MR, Ovendale PJ, Guderian JA, Brandt L, Dillon DC, Campos-Neto A, Lobet Y, Dalemans W, Orme IM and Reed SG (2004) Differential Immune Responses and Protective Efficacy Induced by Components of a Tuberculosis Polyprotein Vaccine, Mtb72F, Delivered as Naked DNA or Recombinant Protein. J. Immunol. 172, 7618-28. http://www.jimmunol.org/cgi/content/abstract/172/12/7618

Sparg SG, Light ME and van Staden J (2004) Biological activities and distribution of plant saponins. Journal of Ethnopharmacology 94, 219-43. http://www.sciencedirect.com/science/article/pii/S0378874104002557

Stewart TJ, Drane D, Malliaros J, Elmer H, Malcolm KM, Cox JC, Edwards SJ, Frazer IH and Fernando GJP (2004) ISCOMATRIX™ adjuvant: an adjuvant suitable for use in anticancer vaccines. Vaccine 22, 3738-43. http://www.sciencedirect.com/science/article/pii/S0264410X04002695

Sun H-X, Ye Y-P, Pan H-J and Pan Y-J (2004) Adjuvant effect of Panax notoginseng saponins on the immune responses to ovalbumin in mice. Vaccine 22, 3882-9. http://www.sciencedirect.com/science/article/pii/S0264410X04003548

Varaldo PB, Leite LCC, Dias WO, Miyaji EN, Torres FIG, Gebara VC, Armoa GRG, Campos AS, Matos DCS, Winter N, Gicquel B, Vilar MM, McFadden J, Almeida MS, Tendler M and McIntosh D (2004) Recombinant Mycobacterium bovis BCG Expressing the Sm14 Antigen of Schistosoma mansoni Protects Mice from Cercarial Challenge. Infect. Immun. 72, 3336-43. http://iai.asm.org/cgi/content/abstract/72/6/3336

Villa-Martinez R, Villagran C and Jenny B (2004) Pollen evidence for late-Holocene climatic variability at Laguna de Aculeo, Central Chile (lat. 34{degrees}S). The Holocene 14, 361-7. http://hol.sagepub.com/cgi/content/abstract/14/3/361

Watt G, Leoff C, Harper AD and Bar-Peled M (2004) A Bifunctional 3,5-Epimerase/4-Keto Reductase for Nucleotide-Rhamnose Synthesis in Arabidopsis. Plant Physiology 134, 1337-46. http://www.plantphysiol.org/cgi/content/abstract/134/4/1337

Zhu X, Yu B, Hui Y and Schmidt Richard R (2004) Synthesis of the Trisaccharide and Tetrasaccharide Moieties of the Potent Immunoadjuvant QS-21. European Journal of Organic Chemistry 2004, 965-73. http://dx.doi.org/10.1002/ejoc.200300580

Anonymous (2003) Chapter 12 Paleoecological sites, cores, and pollen diagrams. In ‘Developments in Quaternary Sciences’. (Ed.^(Eds Heusser CJ) pp. 105-73. (Elsevier). http://www.sciencedirect.com/science/article/pii/S1571086603800155

Anonymous (2003) Chapter 11 Pollen fallout reflective of vegetation during latest centuries: Presettlement and settlement. In ‘Developments in Quaternary Sciences’. (Ed.^(Eds Heusser CJ) pp. 86-104. (Elsevier). http://www.sciencedirect.com/science/article/pii/S1571086603800143

Anonymous (2003) List of figures and tables. In ‘Developments in Quaternary Sciences’. (Ed.^(Eds Heusser CJ) pp. xiii-xvi. (Elsevier). http://www.sciencedirect.com/science/article/pii/S1571086603800039

Anonymous (2003) Current awareness in phytochemical analysis. Phytochemical Analysis 14, 267-74. http://dx.doi.org/10.1002/pca.679

Anonymous (2003) Current literature in mass spectrometry. Journal of Mass Spectrometry 38, 588-95. http://dx.doi.org/10.1002/jms.408

Aburjai T and Natsheh FM (2003) Plants used in cosmetics. Phytotherapy Research 17, 987-1000. http://dx.doi.org/10.1002/ptr.1363

Bienzle U, Gunther M, Neuhaus R, Vandepapeliere P, Vollmar J, Lun A and Neuhaus P (2003) Immunization with an adjuvant hepatitis B vaccine after liver transplantation for hepatitis B-related disease. Hepatology 38, 811-9.

Bienzle U, Günther M, Neuhaus R, Vandepapeliere P, Vollmar J, Lun A and Neuhaus P (2003) Immunization with an adjuvant hepatitis B vaccine after liver transplantation for hepatitis B–related disease. Hepatology 38, 811-9. http://www.sciencedirect.com/science/article/pii/S0270913903007018

Bienzle U, Günther M, Neuhaus R, Vandepapeliere P, Vollmar J, Lun A and Neuhaus P (2003) Immunization with an adjuvant hepatitis B vaccine after liver transplantation for hepatitis B-related disease. Hepatology 38, 811-9. http://dx.doi.org/10.1002/hep.1840380407

Dante J M (2003) Vaccine adjuvants: role and mechanisms of action in vaccine immunogenicity. Drug Discovery Today 8, 934-43. http://www.sciencedirect.com/science/article/pii/S1359644603028642

Dawson NA and Slovin SF (2003) Novel approaches to treat asymptomatic, hormone-naive patients with rising prostate-specific antigen after primary treatment for prostate cancer. Urology 62, Supplement, 102-18. http://www.sciencedirect.com/science/article/pii/S0090429503010768

de Oliveira Mendes C, Paraguai de Souza E, Borja-Cabrera GPc, Maria Melo Batista L, Aparecida dos Santos M, Ellner Parra L, Menz I, Palatnik M and Palatnik de Sousa CB (2003) IgG1/IgG2 antibody dichotomy in sera of vaccinated or naturally infected dogs with visceral leishmaniosis. Vaccine 21, 2589-97. http://www.sciencedirect.com/science/article/pii/S0264410X0300046X

Hansen I, Brimer L and Mřlgaard P (2003) Herbivore-deterring secondary compounds in heterophyllous woody species of the Mascarene Islands. Perspectives in Plant Ecology, Evolution and Systematics 6, 187-203. http://www.sciencedirect.com/science/article/pii/S143383190470075X

Hess HD, Kreuzer M, Dı́az TE, Lascano CE, Carulla JE, Soliva CR and Machmüller A (2003) Saponin rich tropical fruits affect fermentation and methanogenesis in faunated and defaunated rumen fluid. Animal Feed Science and Technology 109, 79-94. http://www.sciencedirect.com/science/article/pii/S0377840103002128

Hristov AN, Ivan M, Neill L and McAllister TA (2003) Evaluation of several potential bioactive agents for reducing protozoal activity in vitro. Animal Feed Science and Technology 105, 163-84. http://www.sciencedirect.com/science/article/pii/S0377840103000609

Hu S, Concha C, Lin F and Persson Waller K (2003) Adjuvant effect of ginseng extracts on the immune responses to immunisation against Staphylococcus aureus in dairy cattle. Veterinary Immunology and Immunopathology 91, 29-37. http://www.sciencedirect.com/science/article/pii/S0165242702002647

Hübschle OJB, Tjipura-Zaire G, Abusugra I, Di Francesca G, Mettler F, Pini A and Morein B (2003) Experimental Field Trial with an Immunostimulating Complex (ISCOM) Vaccine against Contagious Bovine Pleuropneumonia. Journal of Veterinary Medicine, Series B 50, 298-303. http://dx.doi.org/10.1046/j.1439-0450.2003.00659.x

Ilsley SE, Miller HM, Greathead HMR and Kamel C (2003) Plant extracts as supplements for lactating sows: effects on piglet performance, sow food intake and diet digestibility. Animal science : an international journal of fundamental and applied research. 77, 2.

Jassim SAA and Naji MA (2003) Novel antiviral agents: a medicinal plant perspective. Journal of Applied Microbiology 95, 412-27. http://dx.doi.org/10.1046/j.1365-2672.2003.02026.x

Kersten GFA and Crommelin DJA (2003) Liposomes and ISCOMs. Vaccine 21, 915-20. http://www.sciencedirect.com/science/article/pii/S0264410X02005406

Kim SW, Park SK, Kang SI, Kang HC, Oh HJ, Bae CY and Bae DH (2003) Hypocholesterolemic property of Yucca schidigera and Quillaja saponaria extracts in human body. Arch Pharm Res 26, 1042-6.

Liu XS, Xu Y, Hardy L, Khammanivong V, Zhao W, Fernando GJP, Leggatt GR and Frazer IH (2003) IL-10 Mediates Suppression of the CD8 T Cell IFN-{gamma} Response to a Novel Viral Epitope in a Primed Host. J. Immunol. 171, 4765-72. http://www.jimmunol.org/cgi/content/abstract/171/9/4765

Marciani DJ, Reynolds RC, Pathak AK, Finley-Woodman K and May RD (2003) Fractionation, structural studies, and immunological characterization of the semi-synthetic Quillaja saponins derivative GPI-0100. Vaccine 21, 3961-71. http://www.sciencedirect.com/science/article/pii/S0264410X03002986

McGeary RP, Olive C and Toth I (2003) Lipid and carbohydrate based adjuvant/carriers in immunology. Journal of Peptide Science 9, 405-18. http://dx.doi.org/10.1002/psc.467

Nyberg NT, Baumann H and Kenne L (2003) Solid-phase extraction NMR studies of chromatographic fractions of saponins from Quillaja saponaria. Anal Chem 75, 268-74.

Oda K, Matsuda H, Murakami T, Katayama S, Ohgitani T and Yoshikawa M (2003) Relationship between adjuvant activity and amphipathic structure of soyasaponins. Vaccine 21, 2145-51. http://www.sciencedirect.com/science/article/pii/S0264410X02007399

Paul A K (2003) Flow NMR applications in combinatorial chemistry. Current Opinion in Chemical Biology 7, 388-94. http://www.sciencedirect.com/science/article/pii/S1367593103000516

Ragupathi G, Livingston PO, Hood C, Gathuru J, Krown SE, Chapman PB, Wolchok JD, Williams LJ, Oldfield RC and Hwu W-J (2003) Consistent Antibody Response against Ganglioside GD2 Induced in Patients with Melanoma by a GD2 Lactone-Keyhole Limpet Hemocyanin Conjugate Vaccine plus Immunological Adjuvant QS-21. Clin. Cancer Res. 9, 5214-20. http://clincancerres.aacrjournals.org/cgi/content/abstract/9/14/5214

Rivera E, Hu S and Concha C (2003) Ginseng and aluminium hydroxide act synergistically as vaccine adjuvants. Vaccine 21, 1149-57. http://www.sciencedirect.com/science/article/pii/S0264410X02005182

Santos WR, Aguiar IA, de Souza EP, de Lima VMF, Palatnik M and Palatnik-de-Sousa CB (2003) Immunotherapy against murine experimental visceral leishmaniasis with the FML-vaccine. Vaccine 21, 4668-76. http://www.sciencedirect.com/science/article/pii/S0264410X03005279

Sasaki S, Takeshita F, Xin K-Q, Ishii N and Okuda K (2003) Adjuvant formulations and delivery systems for DNA vaccines. Methods 31, 243-54. http://www.sciencedirect.com/science/article/pii/S1046202303001403

Villa-Martínez R, Villagrán C and Jenny B (2003) The last 7500 cal yr B.P. of westerly rainfall in Central Chile inferred from a high-resolution pollen record from Laguna Aculeo (34°S). Quaternary Research 60, 284-93. http://www.sciencedirect.com/science/article/pii/S0033589403001224

Yeates DK, Irwin ME and Wiegmann BM (2003) Ocoidae, a new family of asiloid flies (Diptera: Brachycera: Asiloidea), based on Ocoa chilensis gen. and sp.n. from Chile, South America. Systematic Entomology 28, 417-31. http://dx.doi.org/10.1046/j.1365-3113.2003.00224.x

Yuki Y and Kiyono H (2003) New generation of mucosal adjuvants for the induction of protective immunity. Reviews in Medical Virology 13, 293-310. http://dx.doi.org/10.1002/rmv.398

Zhang P, Yang Q-B, Marciani DJ, Martin M, Clements JD, Michalek SM and Katz J (2003) Effectiveness of the quillaja saponin semi-synthetic analog GPI-0100 in potentiating mucosal and systemic responses to recombinant HagB from Porphyromonas gingivalis. Vaccine 21, 4459-71. http://www.sciencedirect.com/science/article/pii/S0264410X03004389

Anonymous (2002) Correction. Annals of Neurology 51, 799-. http://dx.doi.org/10.1002/ana.1316

Anonymous (2002) Current Awareness. Phytochemical Analysis 13, 181-8. http://dx.doi.org/10.1002/pca.619

Babiuk LA, Babiuk SL and Baca-Estrada ME (2002) Novel vaccine strategies. In ‘Advances in Virus Research’. (Ed.^(Eds  pp. 29-80. (Academic Press). http://www.sciencedirect.com/science/article/pii/S0065352702580027

Bienzle U, Günther M, Neuhaus R and Neuhaus P (2002) Successful hepatitis B vaccination in patients who underwent transplantation for hepatitis B virus–related cirrhosis: Preliminary results. Liver Transplantation 8, 562-4. http://dx.doi.org/10.1053/jlts.2002.33699

Deng X, Meyers SA, Tollner TL, Yudin AI, Primakoff PD, He DN and Overstreet JW (2002) Immunological response of female macaques to the PH-20 sperm protein following injection of recombinant proteins or synthesized peptides. Journal of Reproductive Immunology 54, 93-115. http://www.sciencedirect.com/science/article/pii/S0165037801001243

Fernando GJP, Khammanivong V, Leggatt GR, Liu WJ and Frazer IH (2002) The number of long-lasting functional memory CD8+ T cells generated depends on the nature of the initial nonspecific stimulation. European Journal of Immunology 32, 1541-9. http://dx.doi.org/10.1002/1521-4141(200206)32:6<1541::AID-IMMU1541>3.0.CO;2-S

Fougereau M (2002) Adjuvants. In ‘Encyclopedia of Molecular Biology’. (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/047120918X.emb0027

Francis G, Makkar HPS and Becker K (2002) Dietary supplementation with a Quillaja saponin mixture improves growth performance and metabolic efficiency in common carp (Cyprinus carpio L.). Aquaculture 203, 311-20. http://www.sciencedirect.com/science/article/pii/S0044848601006287

Franconi R, Di Bonito P, Dibello F, Accardi L, Muller A, Cirilli A, Simeone P, Dona MG, Venuti A and Giorgi C (2002) Plant-derived Human Papillomavirus 16 E7 Oncoprotein Induces Immune Response and Specific Tumor Protection. Cancer Res. 62, 3654-8. http://cancerres.aacrjournals.org/cgi/content/abstract/62/13/3654

Furrie E, Smith RE, Turner MW, Strobel S and Mowat AM (2002) Induction of local innate immune responses and modulation of antigen uptake as mechanisms underlying the mucosal adjuvant properties of immune stimulating complexes (ISCOMS). Vaccine 20, 2254-62. http://www.sciencedirect.com/science/article/pii/S0264410X02001068

Huber M, Baier W, Bessler WG and Heinevetter L (2002) Modulation of the Th1/Th2 Bias by Lipopeptide and Saponin Adjuvants in Orally Immunized Mice. Immunobiology 205, 61-73. http://www.sciencedirect.com/science/article/pii/S0171298504700601

Ilsley S, Miller H, Greathead H and Kamel C (2002) Herbal sow diets boost preweaning growth. Feed mix., 3.

Imbimbo BP (2002) Toxicity of β-amyloid vaccination in patients with Alzheimer’s disease. Annals of Neurology 51, 794-. http://dx.doi.org/10.1002/ana.10218

Iosef C, Van Nguyen T, Jeong K-i, Bengtsson K, Morein B, Kim Y, Chang K-O, Azevedo MSP, Yuan L, Nielsen P and Saif LJ (2002) Systemic and intestinal antibody secreting cell responses and protection in gnotobiotic pigs immunized orally with attenuated Wa human rotavirus and Wa 2/6-rotavirus-like-particles associated with immunostimulating complexes. Vaccine 20, 1741-53. http://www.sciencedirect.com/science/article/pii/S0264410X02000312

Kashala O, Amador R, Valero MV, Moreno A, Barbosa A, Nickel B, Daubenberger CA, Guzman F, Pluschke G and Patarroyo ME (2002) Safety, tolerability and immunogenicity of new formulations of the Plasmodium falciparum malaria peptide vaccine SPf66 combined with the immunological adjuvant QS-21. Vaccine 20, 2263-77. http://www.sciencedirect.com/science/article/pii/S0264410X02001159

Kaufman HL, Flanagan K, Lee CSD, Perretta DJ and Horig H (2002) Insertion of interleukin-2 (IL-2) and interleukin-12 (IL-12) genes into vaccinia virus results in effective anti-tumor responses without toxicity. Vaccine 20, 1862-9. http://www.sciencedirect.com/science/article/pii/S0264410X02000324

Liu G, Anderson C, Scaltreto H, Barbon J and Kensil CR (2002) QS-21 structure/function studies: effect of acylation on adjuvant activity. Vaccine 20, 2808-15. http://www.sciencedirect.com/science/article/pii/S0264410X02002098

Lövgren-Bengtsson K and Fossum C (2002) Preparation and use of adjuvants. In ‘Methods in Microbiology’. (Ed.^(Eds Stefan H. E KDK) pp. 551-88. (Academic Press). http://www.sciencedirect.com/science/article/pii/S0580951702321056

Marcian DJ, Ptak RG, Voss TG, Reynolds RC, Pathak AK, Chamblin TL, Scholl DR and May RD (2002) Degradation of Quillaja saponaria Molina saponins: loss of the protective effects of a herpes simplex virus 1 subunit vaccine. Int Immunopharmacol 2, 1703-11.

Marciani DJ, Ptak RG, Voss TG, Reynolds RC, Pathak AK, Chamblin TL, Scholl DR and May RD (2002) Degradation of Quillaja saponaria Molina saponins: loss of the protective effects of a herpes simplex virus 1 subunit vaccine. International Immunopharmacology 2, 1703-11. http://www.sciencedirect.com/science/article/pii/S1567576902001923

Moingeon P, de Taisne C and Almond J (2002) Delivery technologies for human vaccines. Br. Med. Bull. 62, 29-44. http://bmb.oxfordjournals.org/cgi/content/abstract/62/1/29

Murtaugh MP and Foss DL (2002) Inflammatory cytokines and antigen presenting cell activation. Veterinary Immunology and Immunopathology 87, 109-21. http://www.sciencedirect.com/science/article/pii/S0165242702000429

Nicholas RAJ, Ayling RD and Stipkovits LP (2002) An experimental vaccine for calf pneumonia caused by Mycoplasma bovis: clinical, cultural, serological and pathological findings. Vaccine 20, 3569-75. http://www.sciencedirect.com/science/article/pii/S0264410X02003407

Pelah D, Abramovich Z, Markus A and Wiesman Z (2002) The use of commercial saponin from Quillaja saponaria bark as a natural larvicidal agent against Aedes aegypti and Culex pipiens. Journal of Ethnopharmacology 81, 407-9. http://www.sciencedirect.com/science/article/pii/S0378874102001381

Rafi-Janajreh A, Eric Tongren J, Kensil C, Hackett C, Candal F, Lal A and Udhayakumar V (2002) Influence of adjuvants in inducing immune responses to different epitopes included in a multiepitope, multivalent, multistage Plasmodium falciparum candidate vaccine (FALVAC-1) in outbred mice. Experimental Parasitology 101, 3-12. http://www.sciencedirect.com/science/article/pii/S0014489402000292

Ragupathi G, Cappello S, Yi SS, Canter D, Spassova M, Bornmann WG, Danishefsky SJ and Livingston PO (2002) Comparison of antibody titers after immunization with monovalent or tetravalent KLH conjugate vaccines. Vaccine 20, 1030-8. http://www.sciencedirect.com/science/article/pii/S0264410X01004510

Ragupathi G, Deshpande PP, Coltart DM, Kim HM, Williams LJ, Danishefsky SJ and Livingston PO (2002) Constructing an adenocarcinoma vaccine: Immunization of mice with synthetic KH-1 nonasaccharide stimulates anti-KH-1 and anti-Ley antibodies. International Journal of Cancer 99, 207-12. http://dx.doi.org/10.1002/ijc.10305

Santos WR, de Lima VMF, de Souza EP, Bernardo RR, Palatnik M and de Sousa CBP (2002) Saponins, IL12 and BCG adjuvant in the FML-vaccine formulation against murine visceral leishmaniasis. Vaccine 21, 30-43. http://www.sciencedirect.com/science/article/pii/S0264410X02004449

Scanlen M, Paweska JT, Verschoor JA and van Dijk AA (2002) The protective efficacy of a recombinant VP2-based African horsesickness subunit vaccine candidate is determined by adjuvant. Vaccine 20, 1079-88. http://www.sciencedirect.com/science/article/pii/S0264410X01004455

Schaed SG, Klimek VM, Panageas KS, Musselli CM, Butterworth L, Hwu W-J, Livingston PO, Williams L, Lewis JJ, Houghton AN and Chapman PB (2002) T-Cell Responses against Tyrosinase 368-376(370D) Peptide in HLA*A0201+ Melanoma Patients: Randomized Trial Comparing Incomplete Freund’s Adjuvant, Granulocyte Macrophage Colony-stimulating Factor, and QS-21 as Immunological Adjuvants. Clin. Cancer Res. 8, 967-72. http://clincancerres.aacrjournals.org/cgi/content/abstract/8/5/967

Simms JR, Jennings R, Richardson VJ and Heath AW (2002) Large-scale comparison of experimental adjuvants with herpes simplex virus vaccine reveals a correlation of protection with IgG2a and IgG2b responses. Journal of Medical Virology 68, 82-91. http://dx.doi.org/10.1002/jmv.10173

Śliwiński BJ, Soliva CR, Machmüller A and Kreuzer M (2002) Efficacy of plant extracts rich in secondary constituents to modify rumen fermentation. Animal Feed Science and Technology 101, 101-14. http://www.sciencedirect.com/science/article/pii/S0377840102001396

Stchigel AM, Calduch M, Guarro J and Zaror L (2002) A new species of Podospora from soil in Chile. Mycologia 94, 554-8. http://www.mycologia.org/cgi/content/abstract/94/3/554

Stittelaar KJ, Vos HW, van Amerongen G, Kersten GFA, Osterhaus ADME and de Swart RL (2002) Longevity of neutralizing antibody levels in macaques vaccinated with Quil A-adjuvanted measles vaccine candidates. Vaccine 21, 155-7. http://www.sciencedirect.com/science/article/pii/S0264410X0200453X

Turner JL, Dritz SS, Higgins JJ, Herkelman KL and Minton JE (2002) Effects of a Quillaja saponaria extract on growth performance and immune function of weanling pigs challenged with Salmonella typhimurium. J Anim Sci 80, 1939-46. http://jas.fass.org/cgi/content/abstract/80/7/1939

Anonymous (2001) Current Awareness. Phytochemical Analysis 12, 215-22. http://dx.doi.org/10.1002/pca.555

Agger EM and Andersen P (2001) Tuberculosis subunit vaccine development: on the role of interferon-γ. Vaccine 19, 2298-302. http://www.sciencedirect.com/science/article/pii/S0264410X00005193

Andersson C, Wikman M, Lövgren-Bengtsson K, Lundén A and Stĺhl S (2001) In vivo and in vitro lipidation of recombinant immunogens for direct iscom incorporation. Journal of Immunological Methods 255, 135-48. http://www.sciencedirect.com/science/article/pii/S0022175901004306

Boyaka PN, Marinaro M, Jackson RJ, van Ginkel FW, Cormet-Boyaka E, Kirk KL, Kensil CR and McGhee JR (2001) Oral QS-21 Requires Early IL-4 Help for Induction of Mucosal and Systemic Immunity. J. Immunol. 166, 2283-90. http://www.jimmunol.org/cgi/content/abstract/166/4/2283

Cheeke PR (2001) Glycosides: Naturally Occurring. In ‘eLS’. (Ed.^(Eds  pp. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1038/npg.els.0000692

Dabelstein D and Cromer B (2001) Recent developments in human HIV-1 vaccine. Fam. Pract. 18, 230-5. http://fampra.oxfordjournals.org

de Souza JB (2001) Immunization of experimental animals. In ‘eLS’. (Ed.^(Eds  pp. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1038/npg.els.0001439

Dewick PM (2001) The Mevalonate and Deoxyxylulose Phosphate Pathways: Terpenoids and Steroids. In ‘Medicinal Natural Products’. (Ed.^(Eds  pp. 167-289. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/0470846275.ch5

Eschbach E, Scharsack JP, John U and Medlin LK (2001) Improved erythrocyte lysis assay in microtitre plates for sensitive detection and efficient measurement of haemolytic compounds from ichthyotoxic algae. Journal of Applied Toxicology 21, 513-9. http://dx.doi.org/10.1002/jat.797

Evans TG, McElrath MJ, Matthews T, Montefiori D, Weinhold K, Wolff M, Keefer MC, Kallas EG, Corey L, Gorse GJ, Belshe R, Graham BS, Spearman PW, Schwartz D, Mulligan MJ, Goepfert P, Fast P, Berman P, Powell M and Francis D (2001) QS-21 promotes an adjuvant effect allowing for reduced antigen dose during HIV-1 envelope subunit immmunization in humans. Vaccine 19, 2080-91. http://www.sciencedirect.com/science/article/pii/S0264410X00004151

Ghosh A, Labrecque S and Matlashewski G (2001) Protection against Leishmania donovani infection by DNA vaccination: increased DNA vaccination efficiency through inhibiting the cellular p53 response. Vaccine 19, 3169-78. http://www.sciencedirect.com/science/article/pii/S0264410X01000238

Ghosh A, Zhang WW and Matlashewski G (2001) Immunization with A2 protein results in a mixed Th1/Th2 and a humoral response which protects mice against Leishmania donovani infections. Vaccine 20, 59-66. http://www.sciencedirect.com/science/article/pii/S0264410X0100322X

Gozar MMG, Muratova O, Keister DB, Kensil CR, Price VL and Kaslow DC (2001) Plasmodium falciparum: Immunogenicity of Alum-Adsorbed Clinical-Grade TBV25–28, a Yeast-Secreted Malaria Transmission-Blocking Vaccine Candidate. Experimental Parasitology 97, 61-9. http://www.sciencedirect.com/science/article/pii/S0014489400945806

Hu K-F, Chen M, Abusugra I, Monaco F and Morein B (2001) Different respiratory syncytial virus and Quillaja saponin formulations induce murine peritoneal cells to express different proinflammatory cytokine profiles. FEMS Immunology and Medical Microbiology 31, 105-12. http://www.sciencedirect.com/science/article/pii/S0928824401002516

Hu K-F, Lövgren-Bengtsson K and Morein B (2001) Immunostimulating complexes (ISCOMs) for nasal vaccination. Advanced Drug Delivery Reviews 51, 149-59. http://www.sciencedirect.com/science/article/pii/S0169409X0100165X

Marciani DJ, Pathak AK, Reynolds RC, Seitz L and May RD (2001) Altered immunomodulating and toxicological properties of degraded Quillaja saponaria Molina saponins. International Immunopharmacology 1, 813-8. http://www.sciencedirect.com/science/article/pii/S1567576901000169

Miyaji EN, Dias WO, Gamberini M, Gebara VCBC, Schenkman RPF, Wild J, Riedl P, Reimann J, Schirmbeck R and Leite LCC (2001) PsaA (pneumococcal surface adhesin A) and PspA (pneumococcal surface protein A) DNA vaccines induce humoral and cellular immune responses against Streptococcus pneumoniae. Vaccine 20, 805-12. http://www.sciencedirect.com/science/article/pii/S0264410X01003954

Mohamedi SA, Heath AW and Jennings R (2001) A comparison of oral and parenteral routes for therapeutic vaccination with HSV-2 ISCOMs in mice; cytokine profiles, antibody responses and protection. Antiviral Research 49, 83-99. http://www.sciencedirect.com/science/article/pii/S016635420000142X

Mowat AM and Reid G (2001) Preparation of Immune Stimulating Complexes (ISCOMs) as Adjuvants. In ‘Current Protocols in Immunology’. (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/0471142735.im0211s16

Nagai T, Suzuki Y, Kiyohara H, Susa E, Kato T, Nagamine T, Hagiwara Y, Tamura S-i, Yabe T, Aizawa C and Yamada H (2001) Onjisaponins, from the root of Polygala tenuifolia Willdenow, as effective adjuvants for nasal influenza and diphtheria–pertussis–tetanus vaccines. Vaccine 19, 4824-34. http://www.sciencedirect.com/science/article/pii/S0264410X01002158

Nord LI and Kenne L (2001) ChemInform Abstract: Novel Acetylated Triterpenoid Saponins in a Chromatographic Fraction from Quillaja saponaria Molina. ChemInform 32, no-no. http://dx.doi.org/10.1002/chin.200110212

Nord LI, Kenne L and Jacobsson SP (2001) Multivariate analysis of 1H NMR spectra for saponins from Quillaja saponaria Molina. Analytica Chimica Acta 446, 197-207. http://www.sciencedirect.com/science/article/pii/S0003267001009345

O’Hagan DT, MacKichan ML and Singh M (2001) Recent developments in adjuvants for vaccines against infectious diseases. Biomolecular Engineering 18, 69-85. http://www.sciencedirect.com/science/article/pii/S1389034401001010

Polakos NK, Drane D, Cox J, Ng P, Selby MJ, Chien D, O’Hagan DT, Houghton M and Paliard X (2001) Characterization of Hepatitis C Virus Core-Specific Immune Responses Primed in Rhesus Macaques by a Nonclassical ISCOM Vaccine. J. Immunol. 166, 3589-98. http://www.jimmunol.org/cgi/content/abstract/166/5/3589

Rennermalm A, Li Y-H, Bohaufs L, Jarstrand C, Brauner A, Brennan FR and Flock J-I (2001) Antibodies against a truncated Staphylococcus aureus fibronectin-binding protein protect against dissemination of infection in the rat. Vaccine 19, 3376-83. http://www.sciencedirect.com/science/article/pii/S0264410X01000809

Sarria R, Wagner TA, O’Neill MA, Faik A, Wilkerson CG, Keegstra K and Raikhel NV (2001) Characterization of a Family of Arabidopsis Genes Related to Xyloglucan Fucosyltransferase1. Plant Physiology 127, 1595-606. http://www.plantphysiol.org/cgi/content/abstract/127/4/1595

Sjölander A, Drane D, Maraskovsky E, Scheerlinck J-P, Suhrbier A, Tennent J and Pearse M (2001) Immune responses to ISCOM® formulations in animal and primate models. Vaccine 19, 2661-5. http://www.sciencedirect.com/science/article/pii/S0264410X00004977

Toro H, Borie C, Cesario MT and San Martin R (2001) A possible immunomodulatory effect of saponins from Quillaja saponaria in chickens. Proceedings of ... Western Poultry Disease Conference., 171-4.

Turner JL, Dritz SS and Minton JE (2001) REVIEW: Alternatives to Conventional Antimicrobials in Swine Diets. Professional Animal Scientist 17, 217-26. http://pas.fass.org/cgi/content/abstract/17/4/217

Waite DC, Jacobson EW, Ennis FA, Edelman R, White B, Kammer R, Anderson C and Kensil CR (2001) Three double-blind, randomized trials evaluating the safety and tolerance of different formulations of the saponin adjuvant QS-21. Vaccine 19, 3957-67. http://www.sciencedirect.com/science/article/pii/S0264410X01001426

Whitlock C, Bartlein PJ, Markgraf V and Ashworth AC (2001) Chapter 21 - The Midlatitudes of North and South America During the Last Glacial Maximum and Early Holocene: Similar Paleoclimatic Sequences Despite Differing Large-Scale Controls. In ‘Interhemispheric Climate Linkages’. (Ed.^(Eds Vera M) pp. 391-416. (Academic Press: San Diego). http://www.sciencedirect.com/science/article/pii/B9780124726703500240

Wilkes S and Glasl H (2001) Isolation, characterization, and systematic significance of 2-pyrone-4,6-dicarboxylic acid in Rosaceae. Phytochemistry 58, 441-9. http://www.sciencedirect.com/science/article/pii/S0031942201002564

Windon RG, Chaplin PJ, McWaters P, Tavarnesi M, Tzatzaris M, Kimpton WG, Cahill RNP, Beezum L, Coulter A, Drane D, Sjölander A, Pearse M, Scheerlinck JPY and Tennent JM (2001) Local immune responses to influenza antigen are synergistically enhanced by the adjuvant ISCOMATRIX®. Vaccine 20, 490-7. http://www.sciencedirect.com/science/article/pii/S0264410X01003322

Aebischer T, Wolfram M, Patzer SI, Ilg T, Wiese M and Overath P (2000) Subunit Vaccination of Mice against New World Cutaneous Leishmaniasis: Comparison of Three Proteins Expressed in Amastigotes and Six Adjuvants. Infect. Immun. 68, 1328-36. http://iai.asm.org/cgi/content/abstract/68/3/1328

Bilia AR, Nieri E, Braca A and Morelli I (2000) Screening of mediterranean Rosaceae plants for their molluscicidal and piscicidal activities. Phytotherapy Research 14, 126-9. http://dx.doi.org/10.1002/(SICI)1099-1573(200003)14:2<126::AID-PTR553>3.0.CO;2-V

Chapman PB, Morrissey DM, Panageas KS, Hamilton WB, Zhan C, Destro AN, Williams L, Israel RJ and Livingston PO (2000) Induction of Antibodies against GM2 Ganglioside by Immunizing Melanoma Patients Using GM2-Keyhole Limpet Hemocyanin + QS21 Vaccine: A Dose-Response Study. Clin. Cancer Res. 6, 874-9. http://clincancerres.aacrjournals.org/cgi/content/abstract/6/3/874

Cheeke PR (2000) Actual and potential applications of Yucca schidigera and Quillaja saponaria saponins in human and animal nutrition. J Anim Sci 77, 1-h-10. http://jas.fass.org/cgi/content/abstract/77/E-Suppl/1-h

da Fonseca DPAJ, Frerichs J, Singh M, Snippe H and Verheul AFM (2000) Induction of antibody and T-cell responses by immunization with ISCOMS containing the 38-kilodalton protein of Mycobacterium tuberculosis. Vaccine 19, 122-31. http://www.sciencedirect.com/science/article/pii/S0264410X0000102X

Estrada A, Katselis GS, Laarveld B and Barl B (2000) Isolation and evaluation of immunological adjuvant activities of saponins from Polygala senega L. Comparative Immunology, Microbiology and Infectious Diseases 23, 27-43. http://www.sciencedirect.com/science/article/pii/S014795719900020X

Foon KA, Lutzky J, Baral RN, Yannelli JR, Hutchins L, Teitelbaum A, Kashala OL, Das R, Garrison J, Reisfeld RA and Bhattacharya-Chatterjee M (2000) Clinical and Immune Responses in Advanced Melanoma Patients Immunized With an Anti-Idiotype Antibody Mimicking Disialoganglioside GD2. J. Clin. Oncol. 18, 376-. http://jco.ascopubs.org/cgi/content/abstract/18/2/376

Gilewski T, Adluri S, Ragupathi G, Zhang S, Yao T-J, Panageas K, Moynahan M, Houghton A, Norton L and Livingston PO (2000) Vaccination of High-Risk Breast Cancer Patients with Mucin-1 (MUC1) Keyhole Limpet Hemocyanin Conjugate plus QS-21. Clin. Cancer Res. 6, 1693-701. http://clincancerres.aacrjournals.org/cgi/content/abstract/6/5/1693

Guo S, Falk E, Kenne L, Ronnberg B and Sundquist BG (2000) Triterpenoid saponins containing an acetylated branched D-fucosyl residue from Quillaja saponaria Molina. Phytochemistry 53, 861-8.

Guo S, Falk E, Kenne L, Rönnberg B and Sundquist BG (2000) Triterpenoid saponins containing an acetylated branched D-fucosyl residue from Quillaja saponaria Molina. Phytochemistry 53, 861-8. http://www.sciencedirect.com/science/article/pii/S0031942299004227

Guo S, Guo S, Falk E, Kenne L, Ronnberg B and Sundquist BG (2000) Triterpenoids saponins containing and acetylated branched D-fucosyl residue from Quillaja saponaria Molina. Phytochemistry. 53, 861-8.

Guo S and Kenne L (2000) Characterization of some O-acetylated saponins from Quillaja saponaria Molina. Phytochemistry 54, 615-23. http://www.sciencedirect.com/science/article/pii/S0031942200001618

Guo S and Kenne L (2000) Structural studies of triterpenoid saponins with new acyl components from Quillaja saponaria Molina. Phytochemistry 55, 419-28. http://www.sciencedirect.com/science/article/pii/S003194220000340X

Holmgren M, Segura AM and Fuentes ER (2000) Limiting mechanisms in the regeneration of the Chilean matorral. Plant ecology., 1.

Hwang Y-i, Nahm MH, Briles DE, Thomas D and Purkerson JM (2000) Acquired, but Not Innate, Immune Responses to Streptococcus pneumoniae Are Compromised by Neutralization of CD40L. Infect. Immun. 68, 511-7. http://iai.asm.org/cgi/content/abstract/68/2/511

J P (2000) NATURAL PRODUCTS | Thin-Layer (Planar) Chromatography. In ‘Encyclopedia of Separation Science’. (Ed.^(Eds Editor-in-Chief:  Ian DW) pp. 3459-82. (Academic Press: Oxford). http://www.sciencedirect.com/science/article/pii/B0122267702029318

Jabbar IA, Fernando GJP, Saunders N, Aldovini A, Young R, Malcolm K and Frazer IH (2000) Immune responses induced by BCG recombinant for human papillomavirus L1 and E7 proteins. Vaccine 18, 2444-53. http://www.sciencedirect.com/science/article/pii/S0264410X99005502

Johansen P, Men Y, Merkle HP and Gander B (2000) Revisiting PLA/PLGA microspheres: an analysis of their potential in parenteral vaccination. European Journal of Pharmaceutics and Biopharmaceutics 50, 129-46. http://www.sciencedirect.com/science/article/pii/S0939641100000795

Kamstrup S, San Martin R, Doberti A, Grande H and Dalsgaard K (2000) Preparation and characterisation of quillaja saponin with less heterogeneity than Quil-A. Vaccine 18, 2244-9. http://www.sciencedirect.com/science/article/pii/S0264410X99005605

Katayama S, Oda K and Ohgitani T (2000) Influence of antigenic forms and adjuvants on protection against a lethal infection of Aujeszky’s disease virus. Vaccine 19, 54-8. http://www.sciencedirect.com/science/article/pii/S0264410X0000150X

Katz JM, Lu X, Todd CW and Newman MJ (2000) A nonionic block co-polymer adjuvant (CRL1005) enhances the immunogenicity and protective efficacy of inactivated influenza vaccine in young and aged mice. Vaccine 18, 2177-87. http://www.sciencedirect.com/science/article/pii/S0264410X00000220

Kim SK, Ragupathi G, Cappello S, Kagan E and Livingston PO (2000) Effect of immunological adjuvant combinations on the antibody and T-cell response to vaccination with MUC1–KLH and GD3–KLH conjugates. Vaccine 19, 530-7. http://www.sciencedirect.com/science/article/pii/S0264410X0000195X

Lacaille-Dubois MA and Wagner H (2000) Bioactive saponins from plants: An update. In ‘Studies in Natural Products Chemistry’. (Ed.^(Eds Atta ur R) pp. 633-87. (Elsevier). http://www.sciencedirect.com/science/article/pii/S1572599500800150

Mans DRA, da Rocha AB and Schwartsmann G (2000) Anti-Cancer Drug Discovery and Development in Brazil: Targeted Plant Collection as a Rational Strategy to Acquire Candidate Anti-Cancer Compounds. Oncologist 5, 185-98. http://theoncologist.alphamedpress.org/cgi/content/abstract/5/3/185

Marciani DJ, Press JB, Reynolds RC, Pathak AK, Pathak V, Gundy LE, Farmer JT, Koratich MS and May RD (2000) Development of semisynthetic triterpenoid saponin derivatives with immune stimulating activity. Vaccine 18, 3141-51. http://www.sciencedirect.com/science/article/pii/S0264410X00001183

Nascimento IP, Dias WO, Mazzantini RP, Miyaji EN, Gamberini M, Quintilio W, Gebara VC, Cardoso DF, Ho PL, Raw I, Winter N, Gicquel B, Rappuoli R and Leite LCC (2000) Recombinant Mycobacterium bovis BCG Expressing Pertussis Toxin Subunit S1 Induces Protection against an Intracerebral Challenge with Live Bordetella pertussis in Mice. Infect. Immun. 68, 4877-83. http://iai.asm.org/cgi/content/abstract/68/9/4877

Nord LI and Kenne L (2000) Novel acetylated triterpenoid saponins in a chromatographic fraction from Quillaja saponaria Molina. Carbohydrate Research 329, 817-29. http://www.sciencedirect.com/science/article/pii/S0008621500002482

Nyberg NT, Kenne L, Ronnberg B and Sundquist BG (2000) Separation and structural analysis of some saponins from Quillaja saponaria Molina. Carbohydr Res 323, 87-97.

Pinilla-Ibarz J, Cathcart K, Korontsvit T, Soignet S, Bocchia M, Caggiano J, Lai L, Jimenez J, Kolitz J and Scheinberg DA (2000) Vaccination of patients with chronic myelogenous leukemia with bcr-abl oncogene breakpoint fusion peptides generates specific immune responses. Blood 95, 1781-7. http://bloodjournal.hematologylibrary.org/cgi/content/abstract/95/5/1781

Press JB, Reynolds RC, May RD and Marciani DJ (2000) Structure/function relationships of immunostimulating saponins. In ‘Studies in Natural Products Chemistry’. (Ed.^(Eds Atta ur R) pp. 131-74. (Elsevier). http://www.sciencedirect.com/science/article/pii/S1572599500800459

Ragupathi G, Meyers M, Adluri S, Howard L, Musselli C and Livingston PO (2000) Induction of antibodies against GD3 ganglioside in melanoma patients by vaccination with GD3-lactone-KLH conjugate plus immunological adjuvant QS-21. International Journal of Cancer 85, 659-66. http://dx.doi.org/10.1002/(SICI)1097-0215(20000301)85:5<659::AID-IJC11>3.0.CO;2-5

San Martin R and Briones R (2000) Quality control of commercial quillaja (Quillaja saponaria Molina) extracts by reverse phase HPLC. Journal of the science of food and agriculture. 80, 2063-8.

San Martín R and Briones R (2000) Quality control of commercial quillaja (Quillaja saponaria Molina) extracts by reverse phase HPLC. Journal of the Science of Food and Agriculture 80, 2063-8. http://dx.doi.org/10.1002/1097-0010(200011)80:14<2063::AID-JSFA750>3.0.CO;2-2

Schwarz MW (2000) Saponins. In ‘Ullmann’s Encyclopedia of Industrial Chemistry’. (Ed.^(Eds  pp. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/14356007.a23_485

Setten DCv, Zomer G, Werken Gvd, Wiertz EJHJ, Leeflang BR and Kamerling JP (2000) Ion trap multiple-stage tandem mass spectrometry as a pre-NMR tool in the structure elucidation of saponins. Phytochemical analysis : PCA. 11, 190-8.

Simms JR, Heath AW and Jennings R (2000) Use of Herpes Simplex Virus (HSV) Type 1 ISCOMS 703 Vaccine for Prophylactic and Therapeutic Treatment of Primary and Recurrent HSV-2 Infection in Guinea Pigs. The Journal of Infectious Disease 181, 1240-8. http://jid.oxfordjournals.org//cgi/content/abstract/181/4/1240

Stittelaar KJ, Boes J, Kersten GFA, Spiekstra A, Mulder PGH, de Vries P, Roholl PJM, Dalsgaard K, van den Dobbelsteen G, van Alphen L and Osterhaus ADME (2000) In vivo antibody response and in vitro CTL activation induced by selected measles vaccine candidates, prepared with purified Quil A components. Vaccine 18, 2482-93. http://www.sciencedirect.com/science/article/pii/S0264410X00000268

van Setten DC, Zomer G, Werken Gvd, Wiertz EJHJ, Leeflang BR and Kamerling JP (2000) Ion trap multiple-stage tandem mass spectrometry as a pre-NMR tool in the structure elucidation of saponins. Phytochemical Analysis 11, 190-8. http://dx.doi.org/10.1002/(SICI)1099-1565(200005/06)11:3<190::AID-PCA512>3.0.CO;2-2

Virgil Ejc S (2000) Immunological concepts of vaccine adjuvant activity: Commentary. Current Opinion in Immunology 12, 456-63. http://www.sciencedirect.com/science/article/pii/S0952791500001205

Weiner GJ (2000) The immunobiology and clinical potential of immunostimulatory CpG oligodeoxynucleotides. J. Leukoc. Biol. 68, 455-63. http://www.jleukbio.org/cgi/content/abstract/68/4/455

Windon RG, Chaplin PJ, Beezum L, Coulter A, Cahill R, Kimpton W, Drane D, Pearse M, Sjölander A, Tennent JM and Scheerlinck J-PY (2000) Induction of lymphocyte recruitment in the absence of a detectable immune response. Vaccine 19, 572-8. http://www.sciencedirect.com/science/article/pii/S0264410X00001481

Zhu X, Yu B, Hui * Y, Higuchi * R, Kusano T and Miyamoto T (2000) Synthesis and absolute stereochemistry of the acyl moiety of quillajasaponins. Tetrahedron Letters 41, 717-9. http://www.sciencedirect.com/science/article/pii/S0040403999021243

Andersson C, Sandberg L, Murby M, Sjölander A, Lövgren-Bengtsson K and Stĺhl S (1999) General expression vectors for production of hydrophobically tagged immunogens for direct iscom incorporation. Journal of Immunological Methods 222, 171-82. http://www.sciencedirect.com/science/article/pii/S0022175998001951

Beekman NJCM, Schaaper WMM, Turkstra JA and Meloen RH (1999) Highly immunogenic and fully synthetic peptide-carrier constructs targetting GNRH. Vaccine 17, 2043-50. http://www.sciencedirect.com/science/article/pii/S0264410X98004071

Behboudi, Morein and Villacres E (1999) Quillaja Saponin Formulations that Stimulate Proinflammatory Cytokines Elicit a Potent Acquired Cell-Mediated Immunity. Scandinavian Journal of Immunology 50, 371-7. http://dx.doi.org/10.1046/j.1365-3083.1999.00603.x

Brennan FR, Jones TD, Gilleland LB, Bellaby T, Xu F, North PC, Thompson A, Staczek J, Lin T, Johnson JE, Hamilton WDO and Gilleland HE, Jr. (1999) Pseudomonas aeruginosa outer-membrane protein F epitopes are highly immunogenic in mice when expressed on a plant virus. Microbiology 145, 211-20. http://mic.sgmjournals.org/cgi/content/abstract/145/1/211

Brennan FR, Jones TD, Longstaff M, Chapman S, Bellaby T, Smith H, Xu F, Hamilton WDO and Flock JI (1999) Immunogenicity of peptides derived from a fibronectin-binding protein of S. aureus expressed on two different plant viruses. Vaccine 17, 1846-57. http://www.sciencedirect.com/science/article/pii/S0264410X9800485X

Bussiere J, Hardy L, Peterson M, Foss J, Garman R, Hoberman A and Christian M (1999) Lack of developmental neurotoxicity of MN rgp 120/HIV-1 administered subcutaneously to neonatal rats. Toxicol. Sci. 48, 90-9. http://toxsci.oxfordjournals.org/cgi/content/abstract/48/1/90

Cheeke PR (1999) Not just a pretty smell—saponins in animal nutrition. Feed mix., 6.

Crawford SE, Estes MK, Ciarlet M, Barone C, O’Neal CM, Cohen J and Conner ME (1999) Heterotypic Protection and Induction of a Broad Heterotypic Neutralization Response by Rotavirus-Like Particles. J. Virol. 73, 4813-22. http://jvi.asm.org/cgi/content/abstract/73/6/4813

Dickler MN, Ragupathi G, Liu NX, Musselli C, Martino DJ, Miller VA, Kris MG, Brezicka F-T, Livingston PO and Grant SC (1999) Immunogenicity of a Fucosyl-GM1-Keyhole Limpet Hemocyanin Conjugate Vaccine in Patients with Small Cell Lung Cancer. Clin. Cancer Res. 5, 2773-9. http://clincancerres.aacrjournals.org/cgi/content/abstract/5/10/2773

Ekström J, Hu K-F, Bengtsson KL and Morein B (1999) Iscom and iscom-matrix enhance by intranasal route the IgA responses to OVA and rCTB in local and remote mucosal secretions. Vaccine 17, 2690-701. http://www.sciencedirect.com/science/article/pii/S0264410X99000523

Fernando, Murray, Zhou and Frazer (1999) Expression, purification and immunological characterization of the transforming protein E7, from cervical cancer-associated human papillomavirus type 16. Clinical & Experimental Immunology 115, 397-403. http://dx.doi.org/10.1046/j.1365-2249.1999.00813.x

Foon KA, John WJ, Chakraborty M, Das R, Teitelbaum A, Garrison J, Kashala O, Chatterjee SK and Bhattacharya-Chatterjee M (1999) Clinical and Immune Responses in Resected Colon Cancer Patients Treated With Anti-Idiotype Monoclonal Antibody Vaccine That Mimics the Carcinoembryonic Antigen. J. Clin. Oncol. 17, 2889-. http://jco.ascopubs.org/cgi/content/abstract/17/9/2889

Grdic D, Smith R, Donachie A, Kjerrulf M, Hörnquist E, Mowat A and Lycke N (1999) The mucosal adjuvant effects of cholera toxin and immune-stimulating complexes differ in their requirement for IL-12, indicating different pathways of action. European Journal of Immunology 29, 1774-84. http://dx.doi.org/10.1002/(SICI)1521-4141(199906)29:06<1774::AID-IMMU1774>3.0.CO;2-1

Guy B, Hessler C, Fourage S, Rokbi B and Quentin Millet MJ (1999) Comparison between targeted and untargeted systemic immunizations with adjuvanted urease to cure Helicobacter pylori infection in mice. Vaccine 17, 1130-5. http://www.sciencedirect.com/science/article/pii/S0264410X98003326

Harrison GBL, Shakes TR, Robinson CM, Lawrence SB, Heath DD, Dempster RP, Lightowlers MW and Rickard MD (1999) Duration of immunity, efficacy and safety in sheep of a recombinant Taenia ovis vaccine formulated with saponin or selected adjuvants. Veterinary Immunology and Immunopathology 70, 161-72. http://www.sciencedirect.com/science/article/pii/S0165242799000392

Hoshi S, Uchino A, Saito N, Kusanagi K-i, Ihara T and Ueda S (1999) Comparison of adjuvants with respect to serum IgG antibody response in orally immunized chickens. Comparative Immunology, Microbiology and Infectious Diseases 22, 63-9. http://www.sciencedirect.com/science/article/pii/S0147957198000174

Jennemann R, Bauer BL, Bertalanffy H, Selmer T and Wiegandt H (1999) Basidiolipids from Agaricus are Novel Immune Adjuvants. Immunobiology 200, 277-89. http://www.sciencedirect.com/science/article/pii/S017129859980076X

Jiang B, Estes MK, Barone C, Barniak V, O’Neal CM, Ottaiano A, Madore HP and Conner ME (1999) Heterotypic protection from rotavirus infection in mice vaccinated with virus-like particles. Vaccine 17, 1005-13. http://www.sciencedirect.com/science/article/pii/S0264410X9800317X

Jiang B, Estes MK, Barone C, Barniak V, O’Neal CM, Ottaiano A, Madore HP and Conner ME (1999) Heterotypic protection from rotavirus infection in mice vaccinated with virus-like particles. Vaccine 17, 1005-13.

Johansson M and Lövgren-Bengtsson K (1999) Iscoms with different quillaja saponin components differ in their immunomodulating activities. Vaccine 17, 2894-900. http://www.sciencedirect.com/science/article/pii/S0264410X99001280

Kamstrup S, Roensholt L, Jensen MH and Dalsgaard K (1999) Production of a highly immunogenic subunit ISCOM vaccine against Bovine Viral Diarrhea Virus. Vaccine 17, 1057-64. http://www.sciencedirect.com/science/article/pii/S0264410X98003223

Katayama S, Oda K, Ohgitani T, Hirahara T and Shimizu Y (1999) Influence of antigenic forms and adjuvants on the IgG subclass antibody response to Aujeszky’s disease virus in mice. Vaccine 17, 2733-9. http://www.sciencedirect.com/science/article/pii/S0264410X9800499X

Madore HP, Estes MK, Zarley CD, Hu B, Parsons S, Digravio D, Greiner S, Smith R, Jiang B, Corsaro B, Barniak V, Crawford S and Conner ME (1999) Biochemical and immunologic comparison of virus-like particles for a rotavirus subunit vaccine. Vaccine 17, 2461-71. http://www.sciencedirect.com/science/article/pii/S0264410X98003193

Makkar HPS, Aregheore EM and Becker K (1999) Effect of saponins and plant extracts containing saponins on the recovery of ammonia during urea-ammoniation of wheat straw and fermentation kinetics of the treated straw. Journal of agricultural science. 132, 313-21.

McCluskie MJ and Davis HL (1999) Mucosal immunization with DNA vaccines. Microbes and Infection 1, 685-98. http://www.sciencedirect.com/science/article/pii/S1286457999800707

Moore A, McCarthy L and Mills KHG (1999) The adjuvant combination monophosphoryl lipid A and QS21 switches T cell responses induced with a soluble recombinant HIV protein from Th2 to Th1. Vaccine 17, 2517-27. http://www.sciencedirect.com/science/article/pii/S0264410X99000626

Moreno CA, Rodriguez R, Oliveira GA, Ferreira V, Nussenzweig RS, Moya Castro ZR, Calvo-Calle JM and Nardin E (1999) Preclinical evaluation of a synthetic Plasmodium falciparum MAP malaria vaccine in Aotus monkeys and mice. Vaccine 18, 89-99. http://www.sciencedirect.com/science/article/pii/S0264410X9900184X

Nord LI and Kenne L (1999) Separation and structural analysis of saponins in a bark extract from Quillaja saponaria Molina. Carbohydrate Research 320, 70-81. http://www.sciencedirect.com/science/article/pii/S0008621599001342

Nord LI and Kenne L (1999) ChemInform Abstract: Separation and Structural Analysis of Saponins in a Bark Extract from Quillaja saponaria Molina. ChemInform 30, no-no. http://dx.doi.org/10.1002/chin.199952207

Nyberg NT, Kenne L, Rönnberg B and Sundquist BG (1999) Separation and structural analysis of some saponins from Quillaja saponaria Molina. Carbohydrate Research 323, 87-97. http://www.sciencedirect.com/science/article/pii/S000862159900227X

Rajananthanan P, Attard GS, Sheikh NA and Morrow WJW (1999) Novel aggregate structure adjuvants modulate lymphocyte proliferation and Th1 and Th2 cytokine profiles in ovalbumin immunized mice. Vaccine 18, 140-52. http://www.sciencedirect.com/science/article/pii/S0264410X99002133

San Martin R and Briones R (1999) Industrial uses and sustainable supply of Quillaja saponaria (Rosaceae) saponins. Economic botany. 53, 302-11.

Verschoor EJ, Mooij P, Oostermeijer H, van der Kolk M, ten Haaft P, Verstrepen B, Sun Y, Morein B, Akerblom L, Fuller DH, Barnett SW and Heeney JL (1999) Comparison of Immunity Generated by Nucleic Acid-, MF59-, and ISCOM-Formulated Human Immunodeficiency Virus Type 1 Vaccines in Rhesus Macaques: Evidence for Viral Clearance. J. Virol. 73, 3292-300. http://jvi.asm.org/cgi/content/abstract/73/4/3292

Wilson AD, Lövgren-Bengtsson K, Villacres-Ericsson M, Morein B and Morgan AJ (1999) The major Epstein-Barr virus (EBV) envelope glycoprotein gp340 when incorporated into Iscoms primes cytotoxic T-cell responses directed against EBV lymphoblastoid cell lines. Vaccine 17, 1282-90. http://www.sciencedirect.com/science/article/pii/S0264410X9800351X

Wong CP, Okada CY and Levy R (1999) TCR Vaccines Against T Cell Lymphoma: QS-21 and IL-12 Adjuvants Induce a Protective CD8+ T Cell Response. J. Immunol. 162, 2251-8. http://www.jimmunol.org/cgi/content/abstract/162/4/2251

B M (1998) Iscom (Immuno-Stimulating Complex). In ‘Encyclopedia of Immunology (Second Edition)’. (Ed.^(Eds Editor-in-Chief:   Peter JD) pp. 1507-10. (Elsevier: Oxford). http://www.sciencedirect.com/science/article/pii/B0122267656003959

Barr IG, Sjölander A and Cox JC (1998) ISCOMs and other saponin based adjuvants. Advanced Drug Delivery Reviews 32, 247-71. http://www.sciencedirect.com/science/article/pii/S0169409X98000131

Bosio CM and Orme IM (1998) Effective, Nonsensitizing Vaccination with Culture Filtrate Proteins against Virulent Mycobacterium bovis Infections in Mice. Infect. Immun. 66, 5048-51. http://iai.asm.org/cgi/content/abstract/66/10/5048

Chang JCC, Diveley JP, Savary JR and Jensen FC (1998) Adjuvant activity of incomplete Freund’s adjuvant. Advanced Drug Delivery Reviews 32, 173-86. http://www.sciencedirect.com/science/article/pii/S0169409X9800009X

Chao AC, Nguyen JV, Broughall M, Recchia J, Kensil CR, Daddona PE and Fix JA (1998) Enhancement of intestinal model compound transport by DS-1, a modified Quillaja saponin. Journal of Pharmaceutical Sciences 87, 1395-9. http://dx.doi.org/10.1021/js9800735

Ciarlet M, Crawford SE, Barone C, Bertolotti-Ciarlet A, Ramig RF, Estes MK and Conner ME (1998) Subunit Rotavirus Vaccine Administered Parenterally to Rabbits Induces Active Protective Immunity. J. Virol. 72, 9233-46. http://jvi.asm.org/cgi/content/abstract/72/11/9233

Coulter A, Wong T-Y, Drane D, Bates J, Macfarlan R and Cox J (1998) Studies on experimental adjuvanted influenza vaccines: comparison of immune stimulating complexes (Iscoms™) and oil-in-water vaccines. Vaccine 16, 1243-53. http://www.sciencedirect.com/science/article/pii/S0264410X98801254

Deliyannis G, Jackson DC, Dyer W, Bates J, Coulter A, Harling-McNabb L and Brown LE (1998) Immunopotentiation of humoral and cellular responses to inactivated influenza vaccines by two different adjuvants with potential for human use. Vaccine 16, 2058-68. http://www.sciencedirect.com/science/article/pii/S0264410X98000802

Dudas RA and Karron RA (1998) Respiratory Syncytial Virus Vaccines. Clin. Microbiol. Rev. 11, 430-9. http://cmr.asm.org/cgi/content/abstract/11/3/430

Estrada A, Li B and Laarveld B (1998) Adjuvant action of Chenopodium quinoa saponins on the induction of antibody responses to intragastric and intranasal administered antigens in mice. Comparative Immunology, Microbiology and Infectious Diseases 21, 225-36. http://www.sciencedirect.com/science/article/pii/S0147957197000301

Fernández IM, Golding H, Benaissa-Trouw BJ, de Vos NM, Harmsen M, Nottet HSLM, Golding B, Puijk WC, Meloen RH, Snippe H and Kraaijeveld CA (1998) Induction of HIV-1 IIIb neutralizing antibodies in BALBc mice by a chimaeric peptide consisting of a T-helper cell epitope of Semliki Forest virus and a B-cell epitope of HIV. Vaccine 16, 1936-40. http://www.sciencedirect.com/science/article/pii/S0264410X98001285

Fernández IM, Harmsen M, Benaissa-Trouw BJ, Stuij I, Puyk W, Meloen RH, Snippe H and Kraaijeveld CA (1998) Epitope polarity and adjuvants influence the fine specificity of the humoral response against Semliki Forest virus specific peptide vaccines. Vaccine 16, 1531-6. http://www.sciencedirect.com/science/article/pii/S0264410X98000383

Fernando GJP, Stewart TJ, Tindle RW and Frazer IH (1998) Th2-Type CD4+ Cells Neither Enhance nor Suppress Antitumor CTL Activity in a Mouse Tumor Model. J. Immunol. 161, 2421-7. http://www.jimmunol.org/cgi/content/abstract/161/5/2421

Foon KA, Sen G, Hutchins L, Kashala OL, Baral R, Banerjee M, Chakraborty M, Garrison J, Reisfeld RA and Bhattacharya-Chatterjee M (1998) Antibody responses in melanoma patients immunized with an anti-idiotype antibody mimicking disialoganglioside GD2. Clin. Cancer Res. 4, 1117-24. http://clincancerres.aacrjournals.org/cgi/content/abstract/4/5/1117

Giorgio T (1998) Interleukin-12: A Cytokine at the Interface of Inflammation and Immunity. In ‘Advances in Immunology’. (Ed.^(Eds Frank JD) pp. 83-243. (Academic Press). http://www.sciencedirect.com/science/article/pii/S0065277608603879

Guo S, Kenne L, Lundgren LN, Ronnberg B and Sundquist BG (1998) Triterpenoid saponins from Quillaja saponaria. Phytochemistry 48, 175-80.

Guo S, Kenne L, Lundgren LN, Rönnberg B and Sundquist BG (1998) Triterpenoid saponins from Quillaja saponaria. Phytochemistry 48, 175-80. http://www.sciencedirect.com/science/article/pii/S0031942297007164

Guy B, Fourage S, Hessler C, Sanchez V and Millet MJQ (1998) Effects of the Nature of Adjuvant and Site of Parenteral Immunization on the Serum and Mucosal Immune Responses Induced by a Nasal Boost with a Vaccine Alone. Clin. Diagn. Lab. Immunol. 5, 732-6. http://cvi.asm.org/cgi/content/abstract/5/5/732

Guy B, Hessler C, Fourage S, Haensler J, Vialon-Lafay E, Rokbi B and Quentin Millet M-J (1998) Systemic immunization with urease protects mice against Helicobacter pylori infection. Vaccine 16, 850-6. http://www.sciencedirect.com/science/article/pii/S0264410X97002582

Ivins BE, Pitt MLM, Fellows PF, Farchaus JW, Benner GE, Waag DM, Little SF, Anderson Jr GW, Gibbs PH and Friedlander AM (1998) Comparative efficacy of experimental anthrax vaccine candidates against inhalation anthrax in rhesus macaques. Vaccine 16, 1141-8. http://www.sciencedirect.com/science/article/pii/S0264410X98801126

K L-B (1998) 6 Preparation and Use of Adjuvants. In ‘Methods in Microbiology’. (Ed.^(Eds Stefan HEK and Dieter K) pp. 471-502. (Academic Press). http://www.sciencedirect.com/science/article/pii/S0580951708706901

Kensil CR and Kammer R (1998) QS-21: a water-soluble triterpene glycoside adjuvant. Expert Opin Investig Drugs 7, 1475-82.

Kensil CR, Wu JY, Anderson CA, Wheeler DA and Amsden J (1998) QS-21 and QS-7: purified saponin adjuvants. Dev Biol Stand 92, 41-7.

Makkar HPS, Sen S, Blummel M and Becker K (1998) Effects of fractions containing saponins from Yucca schidigera, Quillaja saponaria, and Acaria auriculoformis on rumen fermentation. Journal of agricultural and food chemistry. 46, 4324-238.

Mark J N (1998) Preface. Advanced Drug Delivery Reviews 32, 153-4. http://www.sciencedirect.com/science/article/pii/S0169409X98000076

McNeal MM, Rae MN, Conner ME and Ward RL (1998) Stimulation of Local Immunity and Protection in Mice by Intramuscular Immunization with Triple- or Double-Layered Rotavirus Particles and QS-21. Virology 243, 158-66. http://www.sciencedirect.com/science/article/pii/S0042682298990602

Miller LG (1998) Herbal Medicinals: Selected Clinical Considerations Focusing on Known or Potential Drug-Herb Interactions. Arch Intern Med 158, 2200-11. http://archinte.ama-assn.org/cgi/content/abstract/158/20/2200

Newman MJ, Balusubramanian M and Todd CW (1998) Development of adjuvant-active nonionic block copolymers. Advanced Drug Delivery Reviews 32, 199-223. http://www.sciencedirect.com/science/article/pii/S0169409X98000118

Newman MJ, Todd CW and Balusubramanian M (1998) Design and development of adjuvant-active nonionic block copolymers. Journal of Pharmaceutical Sciences 87, 1357-62. http://dx.doi.org/10.1021/js980072c

O’Hagan DT (1998) Conference Science Medal Lecture: Recent Advances in Vaccine Adjuvants for Systemic and Mucosal Administration*. Journal of Pharmacy and Pharmacology 50, 1-10. http://dx.doi.org/10.1111/j.2042-7158.1998.tb03298.x

Peng S, Frazer IH, Fernando GJ and Zhou J (1998) Papillomavirus Virus-like Particles Can Deliver Defined CTL Epitopes to the MHC Class I Pathway. Virology 240, 147-57. http://www.sciencedirect.com/science/article/pii/S0042682297989121

Sasaki S, Sumino K, Hamajima K, Fukushima J, Ishii N, Kawamoto S, Mohri H, Kensil CR and Okuda K (1998) Induction of Systemic and Mucosal Immune Responses to Human Immunodeficiency Virus Type 1 by a DNA Vaccine Formulated with QS-21 Saponin Adjuvant via Intramuscular and Intranasal Routes. J. Virol. 72, 4931-9. http://jvi.asm.org/cgi/content/abstract/72/6/4931

Sen, Makkar, Muetzel and Becker (1998) Effect of Quillaja saponaria saponins and Yucca schidigera plant extract on growth of Escherichia coli. Letters in Applied Microbiology 27, 35-8. http://dx.doi.org/10.1046/j.1472-765X.1998.00379.x

Sen S, Makkar HP, Muetzel S and Becker K (1998) Effect of Quillaja saponaria saponins and Yucca schidigera plant extract on growth of Escherichia coli. Lett Appl Microbiol 27, 35-8.

Sen S, Makkar HPS, Muetzel S and Becker K (1998) Effect of Quillaja saponaria saponins and Yucca schidigera plant extract on growth of Escherichia coli. Letters in applied microbiology. 27, 35-8.

Sjolander A, Baldwin TM, Curtis JM and Handman E (1998) Induction of a Th1 Immune Response and Simultaneous Lack of Activation of a Th2 Response Are Required for Generation of Immunity to Leishmaniasis. J. Immunol. 160, 3949-57. http://www.jimmunol.org/cgi/content/abstract/160/8/3949

Sjölander A, Baldwin TM, Curtis JM, Lövgren Bengtsson K and Handman E (1998) Vaccination with recombinant Parasite Surface Antigen 2 from Leishmania major induces a Th1 type of immune response but does not protect against infection. Vaccine 16, 2077-84. http://www.sciencedirect.com/science/article/pii/S0264410X98000759

Sjölander A and Cox JC (1998) Uptake and adjuvant activity of orally delivered saponin and ISCOM™ vaccines. Advanced Drug Delivery Reviews 34, 321-38. http://www.sciencedirect.com/science/article/pii/S0169409X98000465

Zhang H, Zhang S, Cheung N-KV, Ragupathi G and Livingston PO (1998) Antibodies against GD2 Ganglioside Can Eradicate Syngeneic Cancer Micrometastases. Cancer Res. 58, 2844-9. http://cancerres.aacrjournals.org/cgi/content/abstract/58/13/2844

Anonymous (1997) Cumulative Subject Index. In ‘Advances in Applied Microbiology’. (Ed.^(Eds Saul LN and Allen IL) pp. 1-166. (Academic Press). http://www.sciencedirect.com/science/article/pii/S0065216408706476

Behboudi S, Morein B and Villacres-Eriksso M (1997) In vivo and in vitro induction of IL-6 by Quillaja saponaria molina triterpenoid formulations. Cytokine 9, 682-7.

Behboudi S, Morein B and Villacres-Eriksson M (1997) IN VIVO AND IN VITRO INDUCTION OF IL-6 BYQUILLAJA SAPONARIAMOLINA TRITERPENOID FORMULATIONS. Cytokine 9, 682-7. http://www.sciencedirect.com/science/article/pii/S1043466697902192

Benne CA, Harmsen M, van der Graaff W, Verheul AFM, Snippe H and Kraaijeveld CA (1997) Influenza virus neutralizing antibodies and IgG isotype profiles after immunization of mice with influenza A subunit vaccine using various adjuvants. Vaccine 15, 1039-44. http://www.sciencedirect.com/science/article/pii/S0264410X96002873

Cox JC and Coulter AR (1997) Adjuvants—a classification and review of their modes of action. Vaccine 15, 248-56. http://www.sciencedirect.com/science/article/pii/S0264410X96001831

Davis D, Morein B, Ĺkerblom L, Lövgren-Bengtsson K, van Gils ME, Bogers WMJM, Teeuwsen VJP and Heeney JL (1997) A recombinant prime, peptide boost vaccination strategy can focus the immune response on to more than one epitope even though these may not be immunodominant in the complex immunogen. Vaccine 15, 1661-9. http://www.sciencedirect.com/science/article/pii/S0264410X97000844

Dotsika E, Karagouni E, Sundquist B, Morein B, Morgan A and Villacres-Eriksso M (1997) Influence of Quillaja saponaria triterpenoid content on the immunomodulatory capacity of Epstein-Barr virus iscoms. Scand J Immunol 45, 261-8.

Dotsika E, Karagouni E, Sundquist B, Morein B, Morgan A and Villacres-Eriksson M (1997) Influence of Quillaja saponaria Triterpenoid Content on the Immunomodulatory Capacity of Epstein–Barr Virus Iscoms. Scandinavian Journal of Immunology 45, 261-8. http://dx.doi.org/10.1046/j.1365-3083.1997.d01-395.x

Fast DJ and Vosika GJ (1997) The muramyl dipeptide analog GMTP-N-DPG preferentially induces cellular immunity to soluble antigens. Vaccine 15, 1748-52. http://www.sciencedirect.com/science/article/pii/S0264410X97001102

John J D (1997) New developments in adjuvants. Mechanisms of Ageing and Development 93, 171-7. http://www.sciencedirect.com/science/article/pii/S0047637496018106

Leung YM, Ou YJ, Kwan CY and Loh TT (1997) Specific interaction between tetrandrine and Quillaja saponins in promoting permeabilization of plasma membrane in human leukemic HL-60 cells. Biochim Biophys Acta 1325, 318-28.

Leung Y-M, Ou Y-J, Kwan C-Y and Loh T-T (1997) Specific interaction between tetrandrine and Quillaja saponins in promoting permeabilization of plasma membrane in human leukemic HL-60 cells. Biochimica et Biophysica Acta (BBA) - Biomembranes 1325, 318-28. http://www.sciencedirect.com/science/article/pii/S0005273697000023

Ling IT, Ogun SA, Momin P, Richards RL, Garçon N, Cohen J, Ballou WR and Holder AA (1997) Immunization against the murine malaria parasite Plasmodium yoelii using a recombinant protein with adjuvants developed for clinical use. Vaccine 15, 1562-7. http://www.sciencedirect.com/science/article/pii/S0264410X97000765

Narai A, Arai S and Shimizu M (1997) Rapid decrease in transepithelial electrical resistance of human intestinal Caco-2 cell monolayers by cytotoxic membrane perturbents. Toxicology in Vitro 11, 347-54. http://www.sciencedirect.com/science/article/pii/S088723339700026X

Neuzil KM, Johnson JE, Tang Y-W, Prieels J-P, Slaoui M, Gar N and Graham BS (1997) Adjuvants influence the quantitative and qualitative immune response in BALBc mice immunized with respiratory syncytial virus FG subunit vaccine. Vaccine 15, 525-32. http://www.sciencedirect.com/science/article/pii/S0264410X97002181

Newman MJ, Todd CW, M. Lee E, Balusubramanian M, Didier PJ and M. Katz J (1997) Increasing the immunogenicity of a trivalent influenza virus vaccine with adjuvant-active nonionic block copolymers for potential use in the elderly. Mechanisms of Ageing and Development 93, 189-203. http://www.sciencedirect.com/science/article/pii/S0047637496018118

Newman MJ, Wu JY, Gardner BH, Anderson CA, Kensil CR, Recchia J, Coughlin RT and Powell MF (1997) Induction of cross-reactive cytotoxic T-lymphocyte responses specific for HIV-1 gp120 using saponin adjuvant (QS-21) supplemented subunit vaccine formulations. Vaccine 15, 1001-7. http://www.sciencedirect.com/science/article/pii/S0264410X96002939

O’Hagan DT, Ott GS and Van Nest G (1997) Recent advances in vaccine adjuvants: the development of MF59 emulsion and polymeric microparticles. Molecular Medicine Today 3, 69-75. http://www.sciencedirect.com/science/article/pii/S1357431096100587

Paul B C (1997) - Clinical studies with anti-idiotypic monoclonal antibody BEC2 that mimics GD3 ganglioside. In ‘Idiotypes in Medicine: Autoimmunity, Infection and Cancer’. (Ed.^(Eds Yehuda S, Ronald CK, Soldano FerroneA2 - Yehuda Shoenfeld RCK and Soldano F) pp. 517-21. (Elsevier Science B.V.: Amsterdam). http://www.sciencedirect.com/science/article/pii/B9780444828071500491

Ronnberg B, Fekadu M, Behboudi S, Kenne L and Morein B (1997) Effects of carbohydrate modification of Quillaja saponaria Molina QH-B fraction on adjuvant activity, cholesterol-binding capacity and toxicity. Vaccine 15, 1820-6.

Rönnberg B, Fekadu M, Behboudi S, Kenne L and Morein B (1997) Effects of carbohydrate modification of Quillaja saponaria Molina QH-B fraction on adjuvant activity, cholesterol-binding capacity and toxicity. Vaccine 15, 1820-6. http://www.sciencedirect.com/science/article/pii/S0264410X97001394

Russo S, Turin L, Zanella A, Ponti W and Poli G (1997) What’s going on in vaccine technology? Medicinal Research Reviews 17, 277-301. http://dx.doi.org/10.1002/(SICI)1098-1128(199705)17:3<277::AID-MED3>3.0.CO;2-V

Santos WR, Bernardo RR, Peçanha LMT, Palatnik M, Parente J and de Sousa CBP (1997) Haemolytic activities of plant saponins and adjuvants. Effect of Periandra mediterranea saponin on the humoral response to the FML antigen of Leishmania donovani. Vaccine 15, 1024-9. http://www.sciencedirect.com/science/article/pii/S0264410X96002927

Sen G, Chakraborty M, Foon KA, Reisfeld RA and Bhattacharya-Chatterjee M (1997) Preclinical evaluation in nonhuman primates of murine monoclonal anti-idiotype antibody that mimics the disialoganglioside GD2. Clin. Cancer Res. 3, 1969-76. http://clincancerres.aacrjournals.org/cgi/content/abstract/3/11/1969

Sjölander A, Bengtsson KL and Morein B (1997) Kinetics, localization and cytokine profile of T cell responses to immune stimulating complexes (iscoms) containing human influenza virus envelope glycoproteins. Vaccine 15, 1030-8. http://www.sciencedirect.com/science/article/pii/S0264410X96002885

So HS, Yoon HS, Choi DY, Kwon YS, Sung JH, Lee TG, Park ES, Cho HS, Lee BM, Cho JM and Ryu WS (1997) Effect of a novel saponin adjuvant derived from Quillaja saponaria on the immune response to recombinant hepatitis B surface antigen. Mol Cells 7, 178-86.

Todd CW, Pozzi LAM, Guarnaccia JR, Balasubramanian M, Henk WG, Younger LE and Newman MJ (1997) Development of an adjuvant-active nonionic block copolymer for use in oil-free subunit vaccines formulations. Vaccine 15, 564-70. http://www.sciencedirect.com/science/article/pii/S0264410X97002090

Villacres-Eriksso M, Behboudi S, Morgan AJ, Trinchieri G and Morein B (1997) Immunomodulation by Quillaja saponaria adjuvant formulations: in vivo stimulation of interleukin 12 and its effects on the antibody response. Cytokine 9, 73-82.

Villacres-Eriksson M, Behboudi S, Morgan AJ, Trinchieri G and Morein B (1997) IMMUNOMODULATION BYQUILLAJA SAPONARIAADJUVANT FORMULATIONS: IN VIVO STIMULATION OF INTERLEUKIN 12 AND ITS EFFECTS ON THE ANTIBODY RESPONSE. Cytokine 9, 73-82. http://www.sciencedirect.com/science/article/pii/S1043466696901398

Anonymous (1996) Key word index. Vaccine 14, viii-xii. http://www.sciencedirect.com/science/article/pii/S0264410X96901073

Anonymous (1996) Bibliography of toxinology. Toxicon 34, 1209-14. http://www.sciencedirect.com/science/article/pii/S0041010196901610

Anonymous (1996) Selected Bibliography. Phytotherapy Research 10, 459-60. http://dx.doi.org/10.1002/ptr.2650100503

Anonymous (1996) Current awareness in phytochemical analysis. Phytochemical Analysis 7, 49-56. http://dx.doi.org/10.1002/pca.2800070102

Andersson S, Makitalo B, Thorstensson R, Franchini G, Tartaglia J, Limbach K, Paoletti E, Putkonen P and Biberfeld G (1996) Immunogenicity and Protective Efficacy of a Human Immunodeficiency Virus Type 2 Recombinant Canarypox (ALVAC) Vaccine Candidate in Cynomolgus Monkeys. The Journal of Infectious Disease 174, 977-85. http://jid.oxfordjournals.org//cgi/content/abstract/174/5/977

Baquiran DC, Dantis L and McKerrow J (1996) Monoclonal antibodies: Innovations in diagnosis and therapy. Seminars in Oncology Nursing 12, 130-41. http://www.sciencedirect.com/science/article/pii/S0749208196800076

Behboudi S, Morein B and Villacres-Eriksso M (1996) In vitro activation of antigen-presenting cells (APC) by defined composition of Quillaja saponaria Molina triterpenoids. Clin Exp Immunol 105, 26-30.

Behboudi S, Morein B and Villacres-Eriksson M (1996) In vitro activation of antigen-presenting cells (APC) by defined composition of Quillaja saponaria Molina triterpenoids. Clinical & Experimental Immunology 105, 26-30. http://dx.doi.org/10.1046/j.1365-2249.1996.d01-730.x

Bengtsson KL and Sjölander A (1996) Adjuvant activity of iscoms; effect of ratio and co-incorporation of antigen and adjuvant. Vaccine 14, 753-60. http://www.sciencedirect.com/science/article/pii/0264410X9500253W

Bhattacharjee AK, Opal SM, Taylor R, Naso R, Semenuk M, Zollinger WD, Moran EE, Young L, Hammack C, Sadoff JC and Cross AS (1996) A Noncovalent Complex Vaccine Prepared with Detoxified Escherichia coli J5 (Rc Chemotype) Lipopolysaccharide and Neisseria meningitidis Group B Outer Membrane Protein Produces Protective Antibodies against Gram-Negative Bacteremia. The Journal of Infectious Disease 173, 1157-63. http://jid.oxfordjournals.org//cgi/content/abstract/173/5/1157

Cleland JL, Kensil CR, Lim A, Jacobsen NE, Basa L, Spellman M, Wheeler DA, Wu JY and Powell MF (1996) Isomerization and formulation stability of the vaccine adjuvant QS-21. J Pharm Sci 85, 22-8.

Dutton G (1996) Saponins draw interest as boosters of immune system. Genetic engineering news : GEN. 16, 1, 32.

Hassan Y, Brewer JM, Alexander J and Jennings R (1996) Immune responses in mice induced by HSV-1 glycoproteins presented with ISCOMs or NISV delivery systems. Vaccine 14, 1581-9. http://www.sciencedirect.com/science/article/pii/S0264410X96001557

Jacobsen NE, Fairbrother WJ, Kensil CR, Lim A, Wheeler DA and Powell MF (1996) Structure of the saponin adjuvant QS-21 and its base-catalyzed isomerization product by 1H and natural abundance 13C NMR spectroscopy. Carbohydrate Research 280, 1-14. http://www.sciencedirect.com/science/article/pii/0008621595002782

Jennemann R, Bauer BL, Schmidt R, Elsasser H-P and Wiegandt H (1996) Effects of Monophosphoryllipid-A on the Immunization of Mice with Keyhole Limpet Hemocyanin- and Muramyldipeptide-Ganglioside Gfpt1 Conjugates. J. Biochem. 119, 378-84. http://jb.oxfordjournals.org/cgi/content/abstract/119/2/378

Keller K (1996) Herbal Medicinal Products in Germany and Europe: Experiences with National and European Assessment. Drug Information Journal 30, 933-48. http://dij.sagepub.com/cgi/content/abstract/30/4/933

Kensil CR (1996) Saponins as vaccine adjuvants. Crit Rev Ther Drug Carrier Syst 13, 1-55.

Kensil CR, Soltysik S, Wheeler DA and Wu JY (1996) Structure/function studies on QS-21, a unique immunological adjuvant from Quillaja saponaria. Adv Exp Med Biol 404, 165-72.

Klita PT, Mathison GW, Fenton TW and Hardin RT (1996) Effects of alfalfa root saponins on digestive function in sheep. J Anim Sci 74, 1144-56. http://jas.fass.org/cgi/content/abstract/74/5/1144

Lacaille-Dubois MA and Wagner H (1996) A review of the biological and pharmacological activities of saponins. Phytomedicine 2, 363-86. http://www.sciencedirect.com/science/article/pii/S094471139680081X

Lundén A, Lövgren Bengtsson K, Sjölander A and Uggla A (1996) Iscoms in parasitological research. Parasitology Today 12, 320-3. http://www.sciencedirect.com/science/article/pii/0169475896100223

Ma J, Hine PM, Clough ER, Fish D, Coughlin RT, Beltz GA and Shew MG (1996) Safety, efficacy, and immunogenicity of a recombinant Osp subunit canine Lyme disease vaccine. Vaccine 14, 1366-74. http://www.sciencedirect.com/science/article/pii/S0264410X9600045X

McCaffery M, Yao TJ, Williams L, Livingston PO, Houghton AN and Chapman PB (1996) Immunization of melanoma patients with BEC2 anti-idiotypic monoclonal antibody that mimics GD3 ganglioside: enhanced immunogenicity when combined with adjuvant. Clin. Cancer Res. 2, 679-86. http://clincancerres.aacrjournals.org/cgi/content/abstract/2/4/679

Ovalle C, Avendańo J, Aronson J and Del Pozo A (1996) Land occupation patterns and vegetation structure in the anthropogenic savannas (espinales) of central Chile. Forest Ecology and Management 86, 129-39. http://www.sciencedirect.com/science/article/pii/S0378112796037863

Pillion DJ, Amsden JA, Kensil CR and Recchia J (1996) Structure-function relationship among Quillaja saponins serving as excipients for nasal and ocular delivery of insulin. J Pharm Sci 85, 518-24.

Pillion DJ, Amsden JA, Kensil CR and Recchia J (1996) Structure—function relationship among Quillaja saponins serving as excipients for nasal and ocular delivery of insulin. Journal of Pharmaceutical Sciences 85, 518-24. http://dx.doi.org/10.1021/js9504651

Shirai M, Chen M, Arichi T, Masaki T, Nishioka M, Newman M, Nakazawa T, Feinstone SM and Berzofsky JA (1996) Use of Intrinsic and Extrinsic Helper Epitopes for In Vivo Induction of Anti-Hepatitis C Virus Cytotoxic T Lymphocytes (CTL) with CTL Epitope Peptide Vaccines. The Journal of Infectious Disease 173, 24-31. http://jid.oxfordjournals.org//cgi/content/abstract/173/1/24

Sjölander S, Hansen J-ES, Lövgren-Bengtsson K, Ĺkerblom L and Morein B (1996) Induction of homologous virus neutralizing antibodies in guinea-pigs immunized with two human immunodeficiency virus type 1 glycoprotein gp120-iscom preparations. A comparison with other adjuvant systems. Vaccine 14, 344-52. http://www.sciencedirect.com/science/article/pii/0264410X9500163U

Stewart-Tull DE (1996) The Use of Adjuvants in Experimental Vaccines : IV. ISCOMS. Methods Mol Med 4, 153-5.

Tomasi M and Hearn TL (1996) 13 - ISCOMs, Liposomes, and Oil-Based Vaccine Delivery Systems. In ‘Mucosal Vaccines’. (Ed.^(Eds Hiroshi K, Pearay LO, Jerry R. McGheeA2 - Hiroshi Kryono PLO and Jerry RM) pp. 175-86. (Academic Press: San Diego). http://www.sciencedirect.com/science/article/pii/B9780124105805500145

van Setten DC and van de Werken G (1996) Molecular structures of saponins from Quillaja saponaria Molina. Adv Exp Med Biol 404, 185-93.

Anonymous (1995) Current Literature in Mass Spectrometry. Journal of Mass Spectrometry 30, 1639-45. http://dx.doi.org/10.1002/jms.1190301120

Behboudi S, Morein B and Ronnberg B (1995) Isolation and quantification of Quillaja saponaria Molina saponins and lipids in iscom-matrix and iscoms. Vaccine 13, 1690-6.

Behboudi S, Morein B and Rönnberg B (1995) Isolation and quantification of Quillaja saponaria Molina saponins and lipids in iscom-matrix and iscoms. Vaccine 13, 1690-6. http://www.sciencedirect.com/science/article/pii/0264410X9500107C

Britt W, Fay J, Seals J and Kensil C (1995) Formulation Of An Immunogenic Human Cytomegalovirus Vaccine: Responses In Mice. The Journal of Infectious Disease 171, 18-25. http://jid.oxfordjournals.org//cgi/content/abstract/171/1/18

Coughlin RT, Fattom A, Chu C, White AC and Winston S (1995) Adjuvant activity of QS-21 for experimental E. coli 018 polysaccharide vaccines. Vaccine 13, 17-21. http://www.sciencedirect.com/science/article/pii/0264410X9580005X

Fattom A, Li X, Cho YH, Burns A, Hawwari A, Shepherd SE, Coughlin R, Winston S and Naso R (1995) Effect of conjugation methodology, carrier protein, and adjuvants on the immune response to Staphylococcus aureus capsular polysaccharides. Vaccine 13, 1288-93. http://www.sciencedirect.com/science/article/pii/0264410X95000523

Fenton RG, Keller CJ, Hanna N and Taub DD (1995) Induction of T-Cell Immunity Against Ras Oncoproteins by Soluble Protein or Ras-Expressing Escherichia coli. J Natl Cancer Inst 87, 1853-61. http://jnci.oxfordjournals.org/cgi/content/abstract/87/24/1853

Gebara VC, Petricevich VL, Raw I and da Silva WD (1995) Effect of saponin from Quillaja saponaria (molina) on antibody, tumour necrosis factor and interferon-gamma production. Biotechnol Appl Biochem 22 ( Pt 1), 31-7.

Gupta RK and Siber GR (1995) Adjuvants for human vaccines—current status, problems and future prospects. Vaccine 13, 1263-76. http://www.sciencedirect.com/science/article/pii/0264410X9500011O

Hancock GE, Speelman DJ, Frenchick PJ, Mineo-Kuhn MM, Baggs RB and Hahn DJ (1995) Formulation of the purified fusion protein of respiratory syncytial virus with the saponin QS-21 induces protective immune responses in Balbc mice that are similar to those generated by experimental infection. Vaccine 13, 391-400. http://www.sciencedirect.com/science/article/pii/0264410X9598263A

Hancock GE, Speelman DJ, Frenchick PJ, Mineo-Kuhn MM, Baggs RB and Hahn DJ (1995) Formulation of the purified fusion protein of respiratory syncytial virus with the saponin QS-21 induces protective immune responses in Balb/c mice that are similar to those generated by experimental infection. Vaccine 13, 391-400.

Helling F, Zhang S, Shang A, Adluri S, Calves M, Koganty R, Longenecker BM, Yao T-J, Oettgen HF and Livingston PO (1995) GM2-KLH Conjugate Vaccine: Increased Immunogenicity in Melanoma Patients after Administration with Immunological Adjuvant QS-21. Cancer Res. 55, 2783-8. http://cancerres.aacrjournals.org/cgi/content/abstract/55/13/2783

Ivins B, Fellows P, Pitt L, Estep J, Farchaus J, Friedlander A and Gibbs P (1995) Experimental anthrax vaccines: efficacy of adjuvants combined with protective antigen against an aerosol Bacillus anthracis spore challenge in guinea pigs. Vaccine 13, 1779-84. http://www.sciencedirect.com/science/article/pii/0264410X9500139R

Iwashina T, Matsumoto S, Nishida M and Nakaike T (1995) New and rare flavonol glycosides from asplenium trichomanes-ramosum as stable chemotaxonomic markers. Biochemical Systematics and Ecology 23, 283-90. http://www.sciencedirect.com/science/article/pii/0305197894E0076R

Kersten GFA and Crommelin DJA (1995) Liposomes and ISCOMS as vaccine formulations. Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes 1241, 117-38. http://www.sciencedirect.com/science/article/pii/0304415795000029

Langeveld JPM, Kamstrup S, Uttenthal A, Strandbygaard B, Vela C, Dalsgaard K, Beekman NJCM, Meloen RH and Casal JI (1995) Full protection in mink against mink enteritis virus with new generation canine parvovirus vaccines based on synthetic peptide or recombinant protein. Vaccine 13, 1033-7. http://www.sciencedirect.com/science/article/pii/0264410X9500021R

Lutz H, Hofmann-Lehmann R, Bauer-Pham K, Holznagel E, Tozzini F, Bendinelli M, Reubel G, Aubert A, Davis D, Cox D and Young E (1995) FIV vaccine studies. I. Immune response to recombinant FIV env gene products and outcome after challenge infection. Veterinary Immunology and Immunopathology 46, 103-13. http://www.sciencedirect.com/science/article/pii/0165242794070105

Ma J, Bulger PA, Dante S, Davis DvR, Perilli-Palmer B and Coughlin RT (1995) Characterization of Canine Humoral Immune Responses to Outer Surface Protein Subunit Vaccines and to Natural Infection by Lyme Disease Spirochetes. The Journal of Infectious Disease 171, 909-15. http://jid.oxfordjournals.org//cgi/content/abstract/171/4/909

Margaret Juliana M (1995) Selection of potent immunological adjuvants for vaccine construction. Seminars in Cancer Biology 6, 375-85. http://www.sciencedirect.com/science/article/pii/1044579X95900071

Philip O L (1995) Augmenting the immunogenicity of carbohydrate tumor antigens. Seminars in Cancer Biology 6, 357-66. http://www.sciencedirect.com/science/article/pii/1044579X95900055

Pillion DJ, Recchia J, Wang P, Marciani DJ and Kensil CR (1995) DS-1, a modified Quillaja saponin, enhances ocular and nasal absorption of insulin. Journal of Pharmaceutical Sciences 84, 1276-9. http://dx.doi.org/10.1002/jps.2600841104

Rao AV and Sung MK (1995) Saponins as anticarcinogens. Journal of nutrition. 125, 717S-24S.

Recchia J, Lurantos MH, Amsden JA, Storey J and Kensil CR (1995) A semisynthetic Quillaja saponin as a drug delivery agent for aminoglycoside antibiotics. Pharm Res 12, 1917-23.

Ronnberg B, Fekadu M and Morein B (1995) Adjuvant activity of non-toxic Quillaja saponaria Molina components for use in ISCOM matrix. Vaccine 13, 1375-82.

Rönnberg B, Fekadu M and Morein B (1995) Adjuvant activity of non-toxic Quillaja saponaria Molina components for use in ISCOM matrix. Vaccine 13, 1375-82. http://www.sciencedirect.com/science/article/pii/0264410X9500105A

Schetters TPM and Montenegro-James S (1995) Vaccines against babesiosis using soluble parasite antigens. Parasitology Today 11, 456-62. http://www.sciencedirect.com/science/article/pii/016947589580059X

Snodgrass DR, Campbell I, Mwenda JM, Chege G, Suleman MA, Morein B and Hart CA (1995) Stimulation of rotavirus IgA, IgG and neutralising antibodies in baboon milk by parenteral vaccination. Vaccine 13, 408-13. http://www.sciencedirect.com/science/article/pii/0264410X9598265C

Soltysik S, Wu JY, Recchia J, Wheeler DA, Newman MJ, Coughlin RT and Kensil CR (1995) Structure/function studies of QS-21 adjuvant: assessment of triterpene aldehyde and glucuronic acid roles in adjuvant function. Vaccine 13, 1403-10.

Soltysik S, Wu J-Y, Recchia J, Wheeler DA, Newman MJ, Coughlin RT and Kensil CR (1995) Structure/function studies of QS-21 adjuvant: assessment of triterpene aldehyde and glucuronic acid roles in adjuvant function. Vaccine 13, 1403-10. http://www.sciencedirect.com/science/article/pii/0264410X9500077E

Starý P (1995) The Aphidiidae of Chile (Hymenoptera, Ichneumonoidea, Aphidiidae). Deutsche Entomologische Zeitschrift 42, 113-38. http://dx.doi.org/10.1002/mmnd.19950420112

Steinbeck C, Schneider C, Rotscheidt K and Breitmaier E (1995) A 4-methyl-7-hydroxyphthalide glycoside and other constituents from Quillaja saponaria molina. Phytochemistry 40, 1313-5. http://www.sciencedirect.com/science/article/pii/003194229500496T

van Setten DC, van de Werken G, Zomer G and Kersten GF (1995) Glycosyl compositions and structural characteristics of the potential immuno-adjuvant active saponins in the Quillaja saponaria Molina extract quil A. Rapid Commun Mass Spectrom 9, 660-6.

van Setten DC, van de Werken G, Zomer G and Kersten GFA (1995) Glycosyl compositions and structural characteristics of the potential immuno-adjuvant active saponins in the Quillaja saponaria Molina extract Quil A. Rapid Communications in Mass Spectrometry 9, 660-6. http://dx.doi.org/10.1002/rcm.1290090808

Vanselow BA, Walthall JC and Abetz I (1995) Field trials of ephemeral fever vaccines. Veterinary Microbiology 46, 117-30. http://www.sciencedirect.com/science/article/pii/037811359500077N

Vc G, Vl P, Raw I and Wd DS (1995) Effect of saponin from Quillaja saponaria (molina) on antibody, tumour necrosis factor and interferon-gamma production. Biotechnology and Applied Biochemistry 22, 31-7. http://dx.doi.org/10.1111/j.1470-8744.1995.tb00341.x

Villacres-Eriksson M (1995) Antigen presentation by naive macrophages, dendritic cells and B cells to primed T lymphocytes and their cytokine production following exposure to immunostimulating complexes. Clinical & Experimental Immunology 102, 46-52. http://dx.doi.org/10.1111/j.1365-2249.1995.tb06634.x

Zhang S, Walberg LA, Ogata S, Itzkowitz SH, Koganty RR, Reddish M, Gandhi SS, Longenecker BM, Lloyd KO and Livingston PO (1995) Immune Sera and Monoclonal Antibodies Define Two Configurations for the Sialyl Tn Tumor Antigen. Cancer Res. 55, 3364-8. http://cancerres.aacrjournals.org/cgi/content/abstract/55/15/3364

Anonymous (1994) Erratum. Phytomedicine 1, 176. http://www.sciencedirect.com/science/article/pii/S0944711311800383

Anonymous (1994) Report on the 3rd International ESCOP-Symposium. Phytomedicine 1, 173-6. http://www.sciencedirect.com/science/article/pii/S0944711311800371

Alonso De Velasco E, Dekker HAT, Antal P, Jalink KP, van Strijp JAG, Verheul AFM, Verhoef J and Snippe H (1994) Adjuvant Quil A improves protection in mice and enhances opsonic capacity of antisera induced by pneumococcal polysaccharide conjugate vaccines. Vaccine 12, 1419-22. http://www.sciencedirect.com/science/article/pii/0264410X94901511

Babiuk LA and Potter AA (1994) Veterinary vaccines. Biotechnology Advances 12, 489-523. http://www.sciencedirect.com/science/article/pii/0734975094900213

Erwin R S (1994) Interaction of bile acids and cholesterol with non-systemic agents having hypocholesterolemic properties. Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism 1210, 255-87. http://www.sciencedirect.com/science/article/pii/0005276094902305

Helling F, Shang A, Calves M, Zhang S, Ren S, Yu RK, Oettgen HF and Livingston PO (1994) GD3 Vaccines for Melanoma: Superior Immunogenicity of Keyhole Limpet Hemocyanin Conjugate Vaccines. Cancer Res. 54, 197-203. http://cancerres.aacrjournals.org/cgi/content/abstract/54/1/197

Jimenez de Bagues MP, Elzer PH, Blasco JM, Marin CM, Gamazo C and Winter AJ (1994) Protective immunity to Brucella ovis in BALB/c mice following recovery from primary infection or immunization with subcellular vaccines. Infect. Immun. 62, 632-8. http://iai.asm.org/cgi/content/abstract/62/2/632

Johnson AG (1994) Molecular adjuvants and immunomodulators: new approaches to immunization. Clin. Microbiol. Rev. 7, 277-89. http://cmr.asm.org/cgi/content/abstract/7/3/277

Kawaguchi M, Kato T, Kamada S and Yahata A (1994) Three-month oral repeated administration toxicity study of seed saponins of thea sinensis L. (ryokucha saponin) in rats. Food and Chemical Toxicology 32, 431-42. http://www.sciencedirect.com/science/article/pii/0278691594900418

Langeveld JP, Casal JI, Osterhaus AD, Cortes E, de Swart R, Vela C, Dalsgaard K, Puijk WC, Schaaper WM and Meloen RH (1994) First peptide vaccine providing protection against viral infection in the target animal: studies of canine parvovirus in dogs. J. Virol. 68, 4506-13. http://jvi.asm.org/cgi/content/abstract/68/7/4506

Langeveld JPM, Ignacio Casal J, Cortés E, van de Wetering G, Boshuizen RS, Schaaper WMM, Dalsgaard K and Meloen RH (1994) Effective induction of neutralizing antibodies with the amino terminus of VP2 of canine parvovirus as a synthetic peptide. Vaccine 12, 1473-80. http://www.sciencedirect.com/science/article/pii/0264410X94901589

Liang W and Huang M (1994) Influence of citrus orchard ground cover plants on arthropod communities in China: A review. Agriculture, Ecosystems &amp; Environment 50, 29-37. http://www.sciencedirect.com/science/article/pii/0167880994901228

Liebermann H, Bartels T, Reimann I and Mundt B (1994) Effect of Adjuvant Formulations on the Induction of Virus-neutralizing and Virus-binding Antibodies by Chemosynthetic Peptides of VP1 of Foot-and-Mouth- Disease Virus. Journal of Veterinary Medicine, Series B 41, 139-44. http://dx.doi.org/10.1111/j.1439-0450.1994.tb00216.x

Livingston PO, Adluri S, Helling F, Yao T-J, Kensilt CR, Newman MJ and Marciani D (1994) Phase 1 trial of immunological adjuvant QS-21 with a GM2 ganglioside-keyhole limpet haemocyanin conjugate vaccine in patients with malignant melanoma. Vaccine 12, 1275-80. http://www.sciencedirect.com/science/article/pii/S0264410X94800522

Ma J, Bulger PA, Davis Dv, Perilli-Palmer B, Bedore DA, Kensil CR, Young EM, Hung C-H, Seals JR, Pavia CS and Coughlin RT (1994) Impact of the saponin adjuvant QS-21 and aluminium hydroxide on the immunogenicity of recombinant OspA and OspB of Borrelia burgdorferi. Vaccine 12, 925-32. http://www.sciencedirect.com/science/article/pii/0264410X94900361

Valensi JP, Carlson JR and Van Nest GA (1994) Systemic cytokine profiles in BALB/c mice immunized with trivalent influenza vaccine containing MF59 oil emulsion and other advanced adjuvants. J. Immunol. 153, 4029-39. http://www.jimmunol.org/cgi/content/abstract/153/9/4029

Anonymous (1993) index. In ‘Advances in Applied Microbiology’. (Ed.^(Eds Saul N and Allen IL) pp. 297-315. (Academic Press). http://www.sciencedirect.com/science/article/pii/S0065216408702181

Fernandez IM, Snijders A, Benaissa-Trouw BJ, Harmsen M, Snippe H and Kraaijeveld CA (1993) Influence of epitope polarity and adjuvants on the immunogenicity and efficacy of a synthetic peptide vaccine against Semliki Forest virus. J. Virol. 67, 5843-8. http://jvi.asm.org/cgi/content/abstract/67/10/5843

Glanz J (1993) Adjuvant rejuvenates vaccine science. Research & development. 35, 53.

Kalin Arroyo MT and Uslar P (1993) Breeding systems in a temperate mediterranean-type climate montane sclerophyllous forest in central Chile. Botanical Journal of the Linnean Society 111, 83-102. http://dx.doi.org/10.1111/j.1095-8339.1993.tb01892.x

Lacaille-Dubois M-A, Hanquet B, Rustaiyan A and Wagner H (1993) Squarroside a, a biologically active triterpene saponin from Acanthophyllum squarrosum. Phytochemistry 34, 489-95. http://www.sciencedirect.com/science/article/pii/003194229380036R

Levy JA (1993) Pathogenesis of human immunodeficiency virus infection. Microbiol. Mol. Biol. Rev. 57, 183-289. http://mmbr.asm.org/cgi/content/abstract/57/1/183

Lilian U T (1993) Potential health benefits and problems associated with antinutrients in foods. Food Research International 26, 131-49. http://www.sciencedirect.com/science/article/pii/096399699390069U

Lillehoj EP and Malik VS (1993) The New Antibody Technologies. In ‘Advances in Applied Microbiology’. (Ed.^(Eds Saul N and Allen IL) pp. 149-209. (Academic Press). http://www.sciencedirect.com/science/article/pii/S0065216408702168

Livingston PO, Calves MJ, Helling F, Zollinger WD, Blake MS and Lowell GH (1993) GD3/proteosome vaccines induce consistent IgM antibodies against the ganglioside GD3. Vaccine 11, 1199-204. http://www.sciencedirect.com/science/article/pii/0264410X9390043W

Ma J and Coughlin RT (1993) A simple, colorimetric microtiter assay for borreliacidal activity of antisera. Journal of Microbiological Methods 17, 145-53. http://www.sciencedirect.com/science/article/pii/0167701293900086

Perraut R, Hundt E, Garraud O, Enders B and Gysin J (1993) Comparison of the effects of adjuvants and adjuvant doses on the quantitative and qualitative antibody response to selected antigens in New World squirrel monkeys Saimiri sciureus. Vaccine 11, 730-6. http://www.sciencedirect.com/science/article/pii/0264410X9390257X

Schneider E (1993) Arzneipflanzen der Neuen Welt. Pharmazie in unserer Zeit 22, 15-24. http://dx.doi.org/10.1002/pauz.19930220107

Soltysik S, Bedore DA and Kensil CR (1993) Adjuvant activity of QS-21 isomers. Ann N Y Acad Sci 690, 392-5.

Starý P, Gerding IM, Norambuena IH and Remaudičre G (1993) Environmental research on aphid parasitoid biocontrol agents in Chile (Hym., Aphidiidae; Hom., Aphidoidea). Journal of Applied Entomology 115, 292-306. http://dx.doi.org/10.1111/j.1439-0418.1993.tb00394.x

Sundfeld E, Krochta JM and Richardson T (1993) SEPARATION of CHOLESTEROL FROM BUTTEROIL USING QUILLAJA SAPONINS. II. EFFECTS of TEMPERATURE, AGITATION and CONCENTRATION of QUILLAJA SOLUTION. Journal of Food Process Engineering 16, 207-27. http://dx.doi.org/10.1111/j.1745-4530.1993.tb00317.x

Sundfeld E, Yun S, Krochta JM and Richardson T (1993) SEPARATION of CHOLESTEROL FROM BUTTEROIL USING QUILLAJA SAPONINS. 1. EFFECTS of PH, CONTACT TIME and ADSORBENT. Journal of Food Process Engineering 16, 191-205. http://dx.doi.org/10.1111/j.1745-4530.1993.tb00316.x

Sundfeld E, Yun S, Krochta JM and Richardson T (1993) Separation of cholesterol from butteroil using Quillaja saponins. I. Effects of pH, contact time and adsorbent. Journal of food process engineering. 16, 191-205.

Anonymous (1992) Glycobiology. Journal of Cellular Biochemistry 50, 133-78. http://dx.doi.org/10.1002/jcb.240500805

Bomford R, Stapleton M, Winsor S, Beesley JE, Jessup EA, Price KR and Fenwick GR (1992) Adjuvanticity and ISCOM formation by structurally diverse saponins. Vaccine 10, 572-7. http://www.sciencedirect.com/science/article/pii/0264410X9290435M

Campbell JB and Peerbaye YA (1992) Saponin. Research in Immunology 143, 526-30. http://www.sciencedirect.com/science/article/pii/092324949280064R

Claassen I and Osterhaus A (1992) The iscom structure as an immune-enhancing moiety: experience with viral systems. Research in Immunology 143, 531-41. http://www.sciencedirect.com/science/article/pii/092324949280065S

Giuseppe Del G (1992) New carriers and adjuvants in the development of vaccines. Current Opinion in Immunology 4, 454-9. http://www.sciencedirect.com/science/article/pii/S0952791506800385

Jiménez HE and Armesto JJ (1992) Importance of the soil seed bank of disturbed sites in Chilean matorral in early secondary succession. Journal of Vegetation Science 3, 579-86. http://dx.doi.org/10.2307/3235824

Kraaijeveld CA, Oosterlaken TAM, Snijders A, Benaissa-Trouw BJ, Ekstijn GL and Snippe H (1992) A vaccine against Semliki Forest virus consisting of a monoclonal anti-idiotypic antibody cross-linked to a protein which contains virus-specific T-helper cell epitopes. Antiviral Research 19, 275-84. http://www.sciencedirect.com/science/article/pii/016635429290009T

Martínez C, Dalsgaard K, López de Turiso J, Cortés E, Vela C and Casal J (1992) Production of porcine parvovirus empty capsids with high immunogenic activity. Vaccine 10, 684-90. http://www.sciencedirect.com/science/article/pii/0264410X92900907

Newman MJ, Wu JY, Gardner BH, Munroe KJ, Leombruno D, Recchia J, Kensil CR and Coughlin RT (1992) Saponin adjuvant induction of ovalbumin-specific CD8+ cytotoxic T lymphocyte responses. J. Immunol. 148, 2357-62. http://www.jimmunol.org/cgi/content/abstract/148/8/2357

Reinhard G (1992) Immunopotentiating reconstituted influenza virosomes (IRIVs) and other adjuvants for improved presentation of small antigens. Vaccine 10, 915-9. http://www.sciencedirect.com/science/article/pii/0264410X9290325E

Wolfender J-L, Maillard M, Marston A and Hostettmann K (1992) Mass spectrometry of underivatized naturally occurring glycosides. Phytochemical Analysis 3, 193-214. http://dx.doi.org/10.1002/pca.2800030502

Wu JY, Gardner BH, Murphy CI, Seals JR, Kensil CR, Recchia J, Beltz GA, Newman GW and Newman MJ (1992) Saponin adjuvant enhancement of antigen-specific immune responses to an experimental HIV-1 vaccine. J. Immunol. 148, 1519-25. http://www.jimmunol.org/cgi/content/abstract/148/5/1519

Jenkins PG, Harris JE and Pulsford AL (1991) Enhanced enteric uptake of human gamma globulin by Quil-A saponin in Oreochromis mossambicus. Fish &amp; Shellfish Immunology 1, 279-95. http://www.sciencedirect.com/science/article/pii/S105046480580066X

Kensil CR, Barrett C, Kushner N, Beltz G, Storey J, Patel U, Recchia J, Aubert A and Marciani D (1991) Development of a genetically engineered vaccine against feline leukemia virus infection. J Am Vet Med Assoc 199, 1423-7.

Kensil CR, Patel U, Lennick M and Marciani D (1991) Separation and characterization of saponins with adjuvant activity from Quillaja saponaria Molina cortex. J. Immunol. 146, 431-7. http://www.jimmunol.org/cgi/content/abstract/146/2/431

Mansilla H, Garcia R, Tapia J, Duran H and Urzua S (1991) Chemical characterization of Chilean hardwoods. Wood science and technology., 2.

Marciani DJ, Kensil CR, Beltz GA, Hung C-h, Cronier J and Aubert A (1991) Genetically-engineered subunit vaccine against feline leukaemia virus: protective immune response in cats. Vaccine 9, 89-96. http://www.sciencedirect.com/science/article/pii/0264410X91902625

Quiroga D, Arretz P and Araya JE (1991) Sucking insects damaging jojoba, Simmondsia chinensis (link) Schneider, and their natural enemies, in the North Central and Central regions of Chile. Crop Protection 10, 469-72. http://www.sciencedirect.com/science/article/pii/S0261219491801353

Reznicek G and Jurenitsch J (1991) Der therapeutische Wert von Triterpensaponinen — Anspruch und Wirklichkeit. Pharmazie in unserer Zeit 20, 278-81. http://dx.doi.org/10.1002/pauz.19910200609

S.B M (1991) Chapter 16 - Glycosides, saponins and sapogenins. In ‘Second Supplements to the 2nd Edition of Rodd’s Chemistry of Carbon Compounds’. (Ed.^(Eds Malcolm S) pp. 509-54. (Elsevier: Amsterdam). http://www.sciencedirect.com/science/article/pii/B9780444533470500847

White AC, Cloutier P and Coughlin RT (1991) A purified saponin acts as an adjuvant for a T-independent antigen. Adv Exp Med Biol 303, 207-10.

C.J H (1990) Ice age vegetation and climate of subtropical Chile. Palaeogeography, Palaeoclimatology, Palaeoecology 80, 107-27. http://www.sciencedirect.com/science/article/pii/003101829090124P

Cook RF, O’Neill T, Strachan E, Sundquist B and Mumford JA (1990) Protection against lethal equine herpes virus type 1 (subtype 1) infection in hamsters by immune stimulating complexes (ISCOMs) containing the major viral glycoproteins. Vaccine 8, 491-6. http://www.sciencedirect.com/science/article/pii/0264410X9090252H

Lussow AR, Aguado MT, Del Giudice G and Lambert P-H (1990) Towards vaccine optimisation. Immunology Letters 25, 255-63. http://www.sciencedirect.com/science/article/pii/0165247890901249

Rong-Tsun W, Hsuch-Ching C, Wan-Chyung F, Kwang-Yu C, Yu-Mei C and Lin-Yea H (1990) Formosanin-C, an immunomodulator with antitumor activity. International Journal of Immunopharmacology 12, 777-86. http://www.sciencedirect.com/science/article/pii/019205619090042L

Anonymous (1988) Polypeptide obtained from HTLV-III gag gene used for detecting AIDS virus and for vaccine preparation. Vaccine 6, 65. http://www.sciencedirect.com/science/article/pii/0264410X88900370

Anonymous (1988) Bovine herpes virus-1 unable to produce functional thymidine kinase and useful in vaccine. Vaccine 6, 65. http://www.sciencedirect.com/science/article/pii/0264410X88900369

Anonymous (1988) Major iron-regulated protein of Neisseria gonorrhoeae and its use as vaccine — obtained from cells grown in iron-depleted culture medium. Vaccine 6, 65. http://www.sciencedirect.com/science/article/pii/0264410X88900436

Anonymous (1988) Cell line HH9/HTLV-III B ATCC CRL-8543 useful for vaccine against AIDS and for detecting antibodies in blood from AIDS patients. Vaccine 6, 65. http://www.sciencedirect.com/science/article/pii/0264410X88900400

Anonymous (1988) Preparation of immunogenic complexes for use in vaccines — ISCOM preparation using e.g. measles virus. Vaccine 6, 65. http://www.sciencedirect.com/science/article/pii/0264410X88900382

Anonymous (1988) New type of human immunodeficiency virus infectious for T4 cells: isolation, characterization, protein sequence determination and cloning in Eschericha coli, AIDS vaccine development, hybridoma for monoclonal antibody secretion. Vaccine 6, 65. http://www.sciencedirect.com/science/article/pii/0264410X88900448

Anonymous (1988) Vaccines for human respiratory virus comprising proteins encoded by a DNA sequence for human respiratory syncytial virus proteins and expressed in a bacterium, yeast or eukaryote host. Vaccine 6, 65. http://www.sciencedirect.com/science/article/pii/0264410X88900357

Anonymous (1988) Moraxella bovis vaccine containing M. bovis protease produced by fermentation. Vaccine 6, 65. http://www.sciencedirect.com/science/article/pii/0264410X88900412

Anonymous (1988) Pseudorabies virus vaccine comprising monoclonal antibody which can be mass produced by hybridoma culture and has high specificity. Vaccine 6, 64-5. http://www.sciencedirect.com/science/article/pii/0264410X88900345

Anonymous (1988) Fractionation of Bordetella pertussis cultures, application for acellular vaccine production. Vaccine 6, 65. http://www.sciencedirect.com/science/article/pii/0264410X88900394

Anonymous (1988) Deletion mutant of a herpes virus and a vaccine containing it, pseudorabies virus mutant construction and characterization. Vaccine 6, 65. http://www.sciencedirect.com/science/article/pii/0264410X88900424

Deans JA, Knight AM, Jean WC, Waters AP, Cohen S and Mitchell GH (1988) Vaccination trials in rhesus monkeys with a minor, invariant, Plasmodium knowlesi 66 kD merozoite antigen. Parasite Immunology 10, 535-52. http://dx.doi.org/10.1111/j.1365-3024.1988.tb00241.x

Higuchi R, Tokimitsu Y and Komori T (1988) An acylated triterpenoid saponin from Quillaja saponaria. Phytochemistry 27, 1165-8. http://www.sciencedirect.com/science/article/pii/0031942288802954

Newmark P (1988) Bark extract amplifies vaccines. Bio/technology. 6, 23.

Speijers GJA, Danse LHJC, Beuvery EC, Strik JJTWA and Vos JG (1988) Local reactions of the saponin Quil A and a Quil A containing iscom measles vaccine after intramuscular injection of rats: A comparison with the effect of DPT-polio vaccine. Fundamental and Applied Toxicology 10, 425-30. http://www.sciencedirect.com/science/article/pii/0272059088902886

Sundquist B, Lövgren K, Höglund S and Morein B (1988) Influenza virus ISCOMs: biochemical characterization. Vaccine 6, 44-8. http://www.sciencedirect.com/science/article/pii/0264410X88900138

Altieri MA, Anderson MK and Merrick LC (1987) Peasant Agriculture and the Conservation of Crop and Wild Plant Resources. Conservation Biology 1, 49-58. http://dx.doi.org/10.1111/j.1523-1739.1987.tb00008.x

Bugg RL (1987) Observations on insects associated with a nectar-bearing Chilean tree, Quillaja saponaria Molina (Rosaceae). Pan-Pacific entomologist. 63, 60-4.

Chavalp SR and Campbell JB (1987) Adjuvant effects of orally administered saponins on humoral and cellular immune responses in mice. Immunobiology 174, 347-59. http://www.sciencedirect.com/science/article/pii/S0171298587800098

Deans JA and Jean WC (1987) Structural studies on a putative Plasmodium knowlesi merozoite antigen. Molecular and Biochemical Parasitology 26, 155-66. http://www.sciencedirect.com/science/article/pii/0166685187901393

Higuchi R and Komori T (1987) Structures of compounds derived from the acyl moieties of quillajasaponin. Phytochemistry 26, 2357-60. http://www.sciencedirect.com/science/article/pii/S0031942200847184

Higuchi R, Tokimitsu Y, Fujioka T, Komori T, Kawasaki T and Oakenful DG (1987) Structure of desacylsaponins obtained from the bark of Quillaja saponaria. Phytochemistry., 1.

K D (1987) Adjuvants. Veterinary Immunology and Immunopathology 17, 145-52. http://www.sciencedirect.com/science/article/pii/0165242787901358

Rao Chavali S, Francis T and Campbell JB (1987) An in vitro study of immunomodulatory effects of some saponins. International Journal of Immunopharmacology 9, 675-83. http://www.sciencedirect.com/science/article/pii/0192056187900385

Trudel M, Nadon F, Seguin C, Boulay G and Lussier G (1987) Vaccination of rabbits with a bovine herpesvirus type 1 subunit vaccine: adjuvant effect of ISCOMs. Vaccine 5, 239-43. http://www.sciencedirect.com/science/article/pii/0264410X87901083

Anonymous (1986) Subject index. Forest Ecology and Management 16, 433-40. http://www.sciencedirect.com/science/article/pii/0378112786900393

Higuchi R, Tokimitsu Y, Fujioka T, Komori T, Kawasaki T and Oakenful DG (1986) Structure of desacylsaponins obtained from the bark of Quillaja saponaria. Phytochemistry 26, 229-35. http://www.sciencedirect.com/science/article/pii/S0031942200815186

Prado JA, Peters R and Aguirre S (1986) Biomass equations for quillay (Quillaja saponaria mol) in the semiarid region of Central Chile. Forest Ecology and Management 16, 41-7. http://www.sciencedirect.com/science/article/pii/037811278690006X

Rao AV and Kendall CW (1986) Dietary saponins and serum lipids. Food and Chemical Toxicology 24, 441. http://www.sciencedirect.com/science/article/pii/0278691586902218

D S-T (1985) Symposium on immunological adjuvants. Vaccine 3, 152-7. http://www.sciencedirect.com/science/article/pii/0264410X85900921

Morein B and Simons K (1985) Subunit vaccines against enveloped viruses: virosomes, micelles and other protein complexes. Vaccine 3, 83-93. http://www.sciencedirect.com/science/article/pii/0264410X85900556

Varshney IP, Beg MFA and Sankaram AVB (1985) Saponins and sapogenins from Quillaia saponaria. Fitoterapia., 4.

McClintock E (1984) Trees of Golden Gate Park: three from South America. Pacific horticulture. 45, 18-20.

Morein B, Sundquist B, Hoglund S, Dalsgaard K and Osterhaus A (1984) Iscom, a novel structure for antigenic presentation of membrane proteins from enveloped viruses. Nature 308, 457-60.

Martinez JA and Armesto JJ (1983) Ecophysiological plasticity and habitat distribution in three evergreen sclerophyllous shrubs of the Chilean matorral. Acta oecologica : oecologia plantarum., 3.

Cisternas RE and Yates LR (1982) Nitrogen in litterfall and precipitation and its release during litter decomposition in the Chilean piedmont matorral. Plant and soil., 3.

Staple RF and Doel TR (1982) Interactions between saponin and 146S particles of foot-and-mouth disease virus. Journal of Biological Standardization 10, 147-56. http://www.sciencedirect.com/science/article/pii/S0092115782800371

Fuentes ER and Etchegaray J (1981) Food preferences of goats: essays with four matorral species of Central Chile. Preferencias de cabras por arbustos: ensayos con cuatro especies del matorral de Chile Central. Ciencia e investigacion agraria. 8, 119-22.

Kummerow J (1981) Carbon allocation to root systems in Mediterranean evergreen sclerophylls. Tasks for vegetation science., 4.

Raghuprasad PK, Brooks SM, Litwin A, Edwards JJ, Bernstein IL and Gallagher J (1980) Quillaja bark (soapbark)-induced asthma. Journal of Allergy and Clinical Immunology 65, 285-7. http://www.sciencedirect.com/science/article/pii/0091674980901578

J.R E (1979) Treatment of ovine foot-rot by vaccination with the specific aetiological agent Bacteroides nodosus. Comparative Immunology, Microbiology and Infectious Diseases 2, 61-7. http://www.sciencedirect.com/science/article/pii/0147957179900596

Prado D JA (1979) Establishment and development in height of Quillaja saponaria Mol.. Prendimiento y desarrollo en altura del quillay (Quillaja saponaria Mol.). Informe tecnico - Instituto Forestal Santiago-Chile. 65, 65.

Guillard J (1978) What is Panama wood? Qu’est ce que le bois de Panama? Revue forestiere francaise 30, 1.

Ebbesen P, Dalsgaard K and Hřier-Madsen M (1976) PROLONGED SURVIVAL OF AKR MICE TREATED WITH THE SAPONIN ADJUVANT QUIL A. Acta Pathologica Microbiologica Scandinavica Section A Pathology 84A, 358-60. http://dx.doi.org/10.1111/j.1699-0463.1976.tb00128.x

Riveros F, Hoffmann A, Avila G, Aljaro ME, Araya S, Hoffmann AE and Montenegro G (1976) Comparative morphological and ecophysiological aspects of two sclerophyllous Chilean shrubs.  165, 3.

Farnsworth NR, Bingel AS, Cordell GA, Crane FA and Fong HHS (1975) Potential value of plants as sources of new antifertility agents I. Journal of Pharmaceutical Sciences 64, 535-98. http://dx.doi.org/10.1002/jps.2600640404

Farnsworth NR, Bingel AS, Cordell GA, Crane FA and Fong HHS (1975) Potential value of plants as sources of new antifertility agents II. Journal of Pharmaceutical Sciences 64, 717-54. http://dx.doi.org/10.1002/jps.2600640504

Rundel PW and Weisser PJ (1975) La Campana, a new national park in central Chile. Biological Conservation 8, 35-46. http://www.sciencedirect.com/science/article/pii/0006320775900774

Dalsgaard K (1974) Saponin adjuvants. 3. Isolation of a substance from Quillaja saponaria Molina with adjuvant activity in food-and-mouth disease vaccines. Arch Gesamte Virusforsch 44, 243-54.

Dalsgaard K (1974) Saponin adjuvants. III. Isolation of a substance from Quillaja saponaria Molina with adjuvant activity in foot-and-mouth disease vaccines. Archiv fur die gesamte Virusforschung 44, 3.

Gaunt IF, Grasso P and Gangolli SD (1974) Short-term toxicity of quillaia xtract in rats. Food and Cosmetics Toxicology 12, 641-50. http://www.sciencedirect.com/science/article/pii/0015626474902351

Kartnig T and Ri CY (1973) Thin-layer chromatography study of saponin from the bark of Quillaja saponaria. Dunnschichtchromatographische Untersuchungen an den Saponinen aus Cortex Quillajae. Planta 23, 3.

Segal R and Taube A (1973) On the configuration of the 16-hydroxyl group in triterpenes: A revision. Tetrahedron 29, 675-8. http://www.sciencedirect.com/science/article/pii/0040402073800778

Dalsgaard K (1972) Saponified adjuvants. I. Presence of a non dialyzable fraction of Quillaja saponaria Molina with adjuvant activity in foot-and-mouth disease vaccines. Adjuvants saponines. I. La presence d’une fraction non dialysable de Quillaja saponaria Molina avec activite adjuvante dans les vaccins anti-aphteux. Bulletin 77, 8.

Dalsgaard K (1972) Saponified adjuvants. II. Influence of the dialysis of the saponin on the effect of local irritation. Adjuvants saponines. II. Influence de la dialyse de la saponine sur l’effet d’irritation locale. Bulletin 77, 8.

Olsen RA (1971) Triterpeneglycosides as Inhibitors of Fungal Growth and Metabolism. Physiologia Plantarum 24, 534-43. http://dx.doi.org/10.1111/j.1399-3054.1971.tb03531.x

Carrington CB and Green TJ (1970) Granular Pneumocytes in Early Repair of Diffuse Alveolar Injury. Arch Intern Med 126, 464-5. http://archinte.ama-assn.org/cgi/content/abstract/126/3/464

Belisário P L (1969) [1] Thin-layer chromatography of steroids, sterols, and related compounds. In ‘Methods in Enzymology’. (Ed.^(Eds Raymond BC) pp. 3-158. (Academic Press). http://www.sciencedirect.com/science/article/pii/S007668796915003X

Anonymous (1966) News and Reports. SMPTE J 75, 436-8. http://hwmaint.journal.smpte.org

B.L O (1966) An evaluation of Yucca mohavensis as a source of food grade saponin. Food and Cosmetics Toxicology 4, 57-61. http://www.sciencedirect.com/science/article/pii/S0015626466803760

Wursthorn K, Wedemeyer H and Manns MP (1966) New SMPTE Sustaining Members

Republished paper: Managing HBV in patients with impaired immunity. SMPTE J 75, 438-. http://hwmaint.journal.smpte.org

http://pmj.bmj.com/cgi/content/abstract/87/1025/223

A.J G (1965) Legal status and toxicity of saponins. Food and Cosmetics Toxicology 3, 85-91. http://www.sciencedirect.com/science/article/pii/S0015626465800128

E.C B-S (1965) Investigation of the chemistry and taxonomy of sub-tribe Quillajeae of the rosaceae using comparisons of fresh and herbarium material. Phytochemistry 4, 535-9. http://www.sciencedirect.com/science/article/pii/S0031942200862135

Tschesche R, Duphorn I and Snatzke G (1963) Über Triterpene, IX. Über die Konstitution der Cincholsäure und die sauren Triterpenglykoside der Chinarinde. Justus Liebigs Annalen der Chemie 667, 151-63. http://dx.doi.org/10.1002/jlac.19636670117

Boyd EM (1954) EXPECTORANTS AND RESPIRATORY TRACT FLUID. Pharmacol. Rev. 6, 521-42. http://pharmrev.aspetjournals.org/cgi/content/abstract/6/4/521

Chambers MA, Zill LP and Noggle GR (1952) The use of ion-exchange resins with glycosides. Journal of the American Pharmaceutical Association 41, 461-4. http://dx.doi.org/10.1002/jps.3030410902

Anonymous (1951) Role of Sterols in Counteracting Growth Depression From High-Alfalfa Feeds. Nutrition Reviews 9, 236-8. http://dx.doi.org/10.1111/j.1753-4887.1951.tb02653.x

Anonymous (1947) Pharmaceutical abstracts. Journal of the American Pharmaceutical Association 36, 193-224. http://dx.doi.org/10.1002/jps.3030361308

Youngken HW and Feldman HS (1942) The pharmacognosy of chionanthus. Journal of the American Pharmaceutical Association 31, 129-35. http://dx.doi.org/10.1002/jps.3030310501

Anonymous (1938) Liste bibliographique. Helvetica Chimica Acta 21, 153-60. http://dx.doi.org/10.1002/hlca.19380210127

Anonymous (1938) American Pharmaceutical Association. Volume IV. December. Journal of the American Pharmaceutical Association 27, 513-76. http://dx.doi.org/10.1002/jps.3080271312

Anonymous (1936) Pharmaceutical abstracts. Journal of the American Pharmaceutical Association 25, 369-416. http://dx.doi.org/10.1002/jps.3080251310

Tschesche T (1935) Die Chemie der Saponine. (Unter besonderer Berücksichtigung der Cyclopenteno-phenanthren-derivate.). Angewandte Chemie 48, 569-73. http://dx.doi.org/10.1002/ange.19350483502

Andrews MJ (1932) An experimental study of the deterioration and assay of spirit of ethyl nitrite. Journal of the American Pharmaceutical Association 21, 886-93. http://dx.doi.org/10.1002/jps.3080210909

Ferchl F (1929) Zur Entstehungsgeschichte des Begriffes Saponin. Archiv der Pharmazie 267, 290-309. http://dx.doi.org/10.1002/ardp.19292670405

Page IH (1923) ASTERIASTEROL—A NEW STEROL FROM THE STARFISH AND THE STEROLS OF CERTAIN OTHER MARINE ECHINODERMS. J. Biol. Chem. 57, 471-6. http://www.jbc.org

Johns CO, Chernoff LH and Viehoever A (1922) A SAPONIN FROM AGAVE LECHUGUILLA TORREY. J. Biol. Chem. 52, 335-47. http://www.jbc.org

Anonymous (1915) Proceedings of the Council. Journal of the American Pharmaceutical Association 4, 1374-86. http://dx.doi.org/10.1002/jps.3080041120

Anonymous (1910) Wirtschaftlich-gewerblicher Teil. Angewandte Chemie 23, 1166-73. http://dx.doi.org/10.1002/ange.19100232505

Singer L (1905) Ueber Neuerungen auf dem Gebiete der Mineralöl-Analyse und Mineralöl-Industrie im Jahre 1904. Chemische Revue über die Fett- und Harz-Industrie 12, 209-14. http://dx.doi.org/10.1002/lipi.19050120904

Schär E (1895) Friedrich August Flückiger. Archiv der Pharmazie 233, 321-89. http://dx.doi.org/10.1002/ardp.18952330502

Anonymous (1887) Pharmacology and Therapeutics. The Lancet 129, 41-2. http://www.sciencedirect.com/science/article/pii/S0140673602374488

Anonymous (1885) Therapeutische Notizen. Archiv der Pharmazie 223, 895-7. http://dx.doi.org/10.1002/ardp.18852232207

Stütz DE (1883) IV. Ueber das Saponin. Justus Liebigs Annalen der Chemie 218, 231-56. http://dx.doi.org/10.1002/jlac.18832180208

Köhler H (1873) In wieweit und in welchem Sinne sind physiologische Versuche an Thieren als Unterstützungsmittel des forensischen Nachweises giftiger Alkaloďde und Glukoside zulässig? Archiv der Pharmazie 202, 244-64. http://dx.doi.org/10.1002/ardp.18732020312

de Bary A (1872) Normalsammlung der Arznei- und Handelspflanzen in getrockneten Exemplaren. Archiv der Pharmazie 201, 286-7. http://dx.doi.org/10.1002/ardp.18722010319

Flückiger FA (1870) Ueber einige Reactionen des Wasserglases. Archiv der Pharmazie 194, 97-106. http://dx.doi.org/10.1002/ardp.18701940202

Smith RE, Donachie AM, Grdic D, Lycke N and Mowat AM (1865) Quarterly Chronicle of Microscopical Science

Immune-Stimulating Complexes Induce an IL-12-Dependent Cascade of Innate Immune Responses. Quarterly Journal of Microscopical Science s2-5, 49-63. http://jcs.biologists.org

http://www.jimmunol.org/cgi/content/abstract/162/9/5536

Anonymous (1850) Saponin. Justus Liebigs Annalen der Chemie 76, 354-. http://dx.doi.org/10.1002/jlac.18500760331

Anonymous (1850) Cumarin in den Fahamblättern. Justus Liebigs Annalen der Chemie 76, 354-. http://dx.doi.org/10.1002/jlac.18500760330

Anonymous Toxicology and Risk Assessment of Coumarin: Focus on Human Data. In ‘Risk Assessment of Phytochemicals in Food’. (Ed.^(Eds  pp. 272-360. (Wiley-VCH Verlag GmbH & Co. KGaA). http://dx.doi.org/10.1002/9783527634705.ch3c

Anonymous Desert King’s Andean surfactants are Ecocert- and NPA-certified. Focus on Surfactants 2010, 2. http://www.sciencedirect.com/science/article/pii/S1351421010701670

Anonymous Glossary. Perspectives in Vaccinology 1, XI-XXII. http://www.sciencedirect.com/science/article/pii/S2210762211000106

Anonymous Acronyms. Vaccine 28, Supplement 3, C41-C2. http://www.sciencedirect.com/science/article/pii/S0264410X10010066

Acharjee S and Sarmah BK Biotechnologically generating ‘super chickpea’ for food and nutritional security. Plant Science. http://www.sciencedirect.com/science/article/pii/S0168945213000344

AdĂŁo CR, da Silva BP and Parente JP A new steroidal saponin with antiinflammatory and antiulcerogenic properties from the bulbs of Allium ampeloprasum var. porrum. Fitoterapia 82, 1175-80. http://www.sciencedirect.com/science/article/pii/S0367326X11001882

AdĂŁo CR, da Silva BP and Parente JP A new steroidal saponin from Allium ampeloprasum var. porrum with antiinflammatory and gastroprotective effects. Phytochemistry Letters 4, 306-10. http://www.sciencedirect.com/science/article/pii/S1874390011000838

Aguerre MJ, Wattiaux MA, Powell JM, Broderick GA and Arndt C Effect of forage-to-concentrate ratio in dairy cow diets on emission of methane, carbon dioxide, and ammonia, lactation performance, and manure excretion. Journal of Dairy Science 94, 3081-93. http://www.sciencedirect.com/science/article/pii/S0022030211002955

Ahlberg V, LÖvgren Bengtsson K, Wallgren P and Fossum C Global transcriptional response to ISCOM-Matrix adjuvant at the site of administration and in the draining lymph node early after intramuscular injection in pigs. Developmental & Comparative Immunology 38, 17-26. http://www.sciencedirect.com/science/article/pii/S0145305X12000432

Ahmed FK, Clark BE, Burton DR and Pantophlet R An engineered mutant of HIV-1 gp120 formulated with adjuvant Quil A promotes elicitation of antibody responses overlapping the CD4-binding site. Vaccine 30, 922-30. http://www.sciencedirect.com/science/article/pii/S0264410X11018858

Alsante KM, Baertschi SW, Coutant M, Marquez BL, Sharp TR, Zelesky TC and Satinder Ahuja and Stephen S 3 - Degradation and Impurity Analysis for Pharmaceutical Drug Candidates. In ‘Separation Science and Technology’. (Ed.^(Eds  pp. 59-169. (Academic Press). http://www.sciencedirect.com/science/article/pii/B9780123756800000036

Altamirano A, Field R, Cayuela L, Aplin P, Lara A and Rey-Benayas JMa Woody species diversity in temperate Andean forests: The need for new conservation strategies. Biological Conservation 143, 2080-91. http://www.sciencedirect.com/science/article/pii/S0006320710002399

Andresen M and Cedergreen N Plant Growth Is Stimulated by Tea-seed Extract: A New Natural Growth Regulator? HortScience 45, 1848-53. http://hortsci.ashspublications.org/cgi/content/abstract/45/12/1848

Arrau S, Delporte C, Cartagena C, RodrÍguez-DÍaz M, GonzÁlez P, Silva X, Cassels BK and Miranda HF Antinociceptive activity of Quillaja saponaria Mol. saponin extract, quillaic acid and derivatives in mice. Journal of ethnopharmacology. 133, 164-7. http://dx.doi.org/10.1016/j.jep.2010.09.016

Arrau S, Delporte C, Cartagena C, Rodriguez-Diaz M, Gonzalez P, Silva X, Cassels BK and Miranda HF Antinociceptive activity of Quillaja saponaria Mol. saponin extract, quillaic acid and derivatives in mice. J Ethnopharmacol 133, 164-7.

Au F, McKeown LE, McAllister TA and Chaves AV Fermentation characteristics of corn-, triticale-, and wheat-based dried distillers’ grains with solubles in barley-based diets determined using continuous and batch culture systems. Journal of the Science of Food and Agriculture 90, 2074-82. http://dx.doi.org/10.1002/jsfa.4054

Augustin JrM, Kuzina V, Andersen SB and Bak Sr Molecular activities, biosynthesis and evolution of triterpenoid saponins. Phytochemistry 72, 435-57. http://www.sciencedirect.com/science/article/pii/S0031942211000410

Avila JS, Chaves AV, Hernandez-Calva M, Beauchemin KA, McGinn SM, Wang Y, Harstad OM and McAllister TA Effects of replacing barley grain in feedlot diets with increasing levels of glycerol on in vitro fermentation and methane production. Animal Feed Science and Technology 166–167, 265-8. http://www.sciencedirect.com/science/article/pii/S0377840111001350

Awad E and Austin B Use of lupin, Lupinus perennis, mango, Mangifera indica, and stinging nettle, Urtica dioica, as feed additives to prevent Aeromonas hydrophila infection in rainbow trout, Oncorhynchus mykiss (Walbaum). Journal of Fish Diseases 33, 413-20. http://dx.doi.org/10.1111/j.1365-2761.2009.01133.x

Awad E, Austin D and Lyndon AR Effect of black cumin seed oil (Nigella sativa) and nettle extract (Quercetin) on enhancement of immunity in rainbow trout, Oncorhynchus mykiss (Walbaum). Aquaculture 388–391, 193-7. http://www.sciencedirect.com/science/article/pii/S0044848613000124

Axelsen TV, Holm A, Christiansen G and Birkelund S Identification of the shortest Aβ-peptide generating highly specific antibodies against the C-terminal end of amyloid-β42. Vaccine 29, 3260-9. http://www.sciencedirect.com/science/article/pii/S0264410X11002398

Bachran D, Schneider S, Bachran C, Urban R, Weng A, Melzig MF, Hoffmann C, Kaufmann AM and Fuchs H Epidermal growth factor receptor expression affects the efficacy of the combined application of saponin and a targeted toxin on human cervical carcinoma cells. International Journal of Cancer 127, 1453-61. http://dx.doi.org/10.1002/ijc.25123

Badiee A, Heravi Shargh V, Khamesipour A and Jaafari MR Micro/nanoparticle adjuvants for antileishmanial vaccines: Present and future trends. Vaccine 31, 735-49. http://www.sciencedirect.com/science/article/pii/S0264410X12017185

Ballou WR and Cohen J 53 - Malaria vaccines. In ‘Vaccines (Sixth Edition)’. (Ed.^(Eds  pp. 1133-7. (W.B. Saunders: London). http://www.sciencedirect.com/science/article/pii/B9781455700905000562

Banerjee K, Andjelic S, Klasse PJ, Kang Y, Sanders RW, Michael E, Durso RJ, Ketas TJ, Olson WC and Moore JP Enzymatic removal of mannose moieties can increase the immune response to HIV-1 gp120 in vivo. Virology 389, 108-21. http://www.sciencedirect.com/science/article/pii/S0042682209002360

Bankefors J, Broberg S, Nord LI and Kenne L Electrospray ionization ion-trap multiple-stage mass spectrometry of Quillaja saponins. J Mass Spectrom 46, 658-65.

Bankefors J, Nord LI and Kenne L Multidimensional profiling of components in complex mixtures of natural products for metabolic analysis, proof of concept: application to Quillaja saponins. J Chromatogr B Analyt Technol Biomed Life Sci 878, 471-6.

Barbosa AdP, da Silva BP and Parente JP A new complex triterpenoid saponin from Samanea saman with haemolytic activity and adjuvant effect. Phytochemistry Letters. http://www.sciencedirect.com/science/article/pii/S187439001200122X

Barhate G, Gautam M, Gairola S, Jadhav S and Pokharkar V Quillaja saponaria extract as mucosal adjuvant with chitosan functionalized gold nanoparticles for mucosal vaccine delivery: Stability and immunoefficiency studies. International Journal of Pharmaceutics 441, 636-42. http://www.sciencedirect.com/science/article/pii/S0378517312009738

Batista-Duharte A, Lastre M and PÉrez O Adyuvantes inmunolÓgicos. Determinantes en el balance eficacia-toxicidad de las vacunas contemporÁneas. Enfermedades Infecciosas y MicrobiologÍa ClÍnica. http://www.sciencedirect.com/science/article/pii/S0213005X1200434X

Becerra PI, González-Rodríguez V, Smith-Ramírez C and Armesto JJ Spatio-temporal variation in the effect of herbaceous layer on woody seedling survival in a Chilean mediterranean ecosystem. Journal of Vegetation Science 22, 847-55. http://dx.doi.org/10.1111/j.1654-1103.2011.01291.x

Bednarczyk-Cwynar B, Zaprutko L, Marciniak J, Lewandowski G, Szulc M, Kaminska E, Wachowiak N and Mikolajczak PL The analgesic and anti-inflammatory effect of new oleanolic acid acyloxyimino derivative. European Journal of Pharmaceutical Sciences 47, 549-55. http://www.sciencedirect.com/science/article/pii/S0928098712002953

Bello MA, Rudall PJ and Hawkins JA Combined phylogenetic analyses reveal interfamilial relationships and patterns of floral evolution in the eudicot order Fabales. Cladistics, no-no. http://dx.doi.org/10.1111/j.1096-0031.2012.00392.x

Berezin VE, Bogoyavlenskyi AP, Khudiakova SS, Alexuk PG, Omirtaeva ES, Zaitceva IA, Tustikbaeva GB, Barfield RC and Fetterer RH Immunostimulatory complexes containing Eimeria tenella antigens and low toxicity plant saponins induce antibody response and provide protection from challenge in broiler chickens. Veterinary Parasitology 167, 28-35. http://www.sciencedirect.com/science/article/pii/S0304401709005974

Bernal J, Ares AM, PÓl J and Wiedmer SK Hydrophilic interaction liquid chromatography in food analysis. Journal of Chromatography A 1218, 7438-52. http://www.sciencedirect.com/science/article/pii/S0021967311006182

Beylot Gr Les cosmÉtiques minceur. ActualitÉs Pharmaceutiques 49, 55-8. http://www.sciencedirect.com/science/article/pii/S0515370010706819

Bodas R, Prieto N, GarcÍa-GonzÁlez R, AndrÉs S, GirÁldez FJ and LÓpez S Manipulation of rumen fermentation and methane production with plant secondary metabolites. Animal Feed Science and Technology 176, 78-93. http://www.sciencedirect.com/science/article/pii/S037784011200243X

Bodas R, Prieto N, García-González R, Andrés S, Giráldez FJ and López S Manipulation of rumen fermentation and methane production with plant secondary metabolites. Animal Feed Science and Technology. http://www.sciencedirect.com/science/article/pii/S037784011200243X

Borja-Cabrera GP, Santos FN, Santos FB, Trivellato FAdA, Kawasaki JKA, Costa AC, Castro T, Nogueira FS, Moreira MAB, Luvizotto MCR, Palatnik M and Palatnik-de-Sousa CB Immunotherapy with the saponin enriched-Leishmune® vaccine versus immunochemotherapy in dogs with natural canine visceral leishmaniasis. Vaccine 28, 597-603. http://www.sciencedirect.com/science/article/pii/S0264410X09014182

Boysen RI, Hearn MTW, Editors-in-Chief:Â Â Lew M and Hung-Wen L 9.02 - High Performance Liquid Chromatographic Separation Methods. In ‘Comprehensive Natural Products II’. (Ed.^(Eds  pp. 5-49. (Elsevier: Oxford). http://www.sciencedirect.com/science/article/pii/B9780080453828001830

Buxton D, Uggla A, Lövgren K, Thomson K, Lundén A, Morein B and Blewett DA Trial of a novel experimental Toxoplasma iscom vaccine in pregnant sheep. British Veterinary Journal 145, 451-7. http://www.sciencedirect.com/science/article/pii/0007193589900535

Cares MG, Vargas Y, Gaete L, Sainz J and AlarcÓn J Ultrasonically assisted extraction of bioactive principles from Quillaja Saponaria Molina. Physics Procedia 3, 169-78. http://www.sciencedirect.com/science/article/pii/S1875389210000258

Carlson D, Fernandez JA, Poulsen HD, Nielsen B and Jacobsen SE Effects of quinoa hull meal on piglet performance and intestinal epithelial physiology. Journal of Animal Physiology and Animal Nutrition 96, 198-205. http://dx.doi.org/10.1111/j.1439-0396.2011.01138.x

Casares S, Brumeanu T-D and Richie TL The RTS,S malaria vaccine. Vaccine 28, 4880-94. http://www.sciencedirect.com/science/article/pii/S0264410X10007218

Castellani RJ, Rolston RK and Smith MA Alzheimer Disease. Disease-a-Month 56, 484-546. http://www.sciencedirect.com/science/article/pii/S0011502910000684

Castro-DÍaz N, Salaun B, Perret R, Sierro S, Romero JF, FernÁndez J-A, Rubio-Moraga A and Romero P Saponins from the Spanish saffron Crocus sativus are efficient adjuvants for protein-based vaccines. Vaccine 30, 388-97. http://www.sciencedirect.com/science/article/pii/S0264410X11017300

Castro-Díaz N, Salaun B, Perret R, Sierro S, Romero JF, Fernández J-A, Rubio-Moraga A and Romero P Saponins from the Spanish saffron Crocus sativus are efficient adjuvants for protein-based vaccines. Vaccine. http://www.sciencedirect.com/science/article/pii/S0264410X11017300

Castro-Montoya J, De Campeneere S, Van Ranst G and Fievez V Interactions between methane mitigation additives and basal substrates on in vitro methane and VFA production. Animal Feed Science and Technology. http://www.sciencedirect.com/science/article/pii/S0377840112002404

CecÍlio AB, Faria DbBd, Oliveira PdC, Caldas Sr, Oliveira DAd, Sobral MEG, Duarte MGR, Moreira CPdS, Silva CuG and Almeida VLcd Screening of Brazilian medicinal plants for antiviral activity against rotavirus. Journal of Ethnopharmacology 141, 975-81. http://www.sciencedirect.com/science/article/pii/S0378874112001912

ChÁvez-Fumagalli MA, Costa MAF, Oliveira DM, RamÍrez L, Costa LE, Duarte MC, Martins VT, Oliveira JS, Olortegi CC, Bonay P, Alonso C, Tavares CAP, Soto M and Coelho EAF Vaccination with the Leishmania infantum ribosomal proteins induces protection in BALB/c mice against Leishmania chagasi and Leishmania amazonensis challenge. Microbes and Infection 12, 967-77. http://www.sciencedirect.com/science/article/pii/S1286457910001607

Chadwick S, Kriegel C and Amiji M Nanotechnology solutions for mucosal immunization. Advanced Drug Delivery Reviews 62, 394-407. http://www.sciencedirect.com/science/article/pii/S0169409X09003536

Chandler D, Bailey AS, Tatchell GM, Davidson G, Greaves J and Grant WP The development, regulation and use of biopesticides for integrated pest management. Phil Trans R Soc B 366, 1987-98. http://rstb.royalsocietypublishing.org/cgi/content/abstract/366/1573/1987

Chaudhry AS and Khan MMH Impacts of different spices on in vitro rumen dry matter disappearance, fermentation and methane of wheat or ryegrass hay based substrates. Livestock Science 146, 84-90. http://www.sciencedirect.com/science/article/pii/S1871141312000339

Chen W, Ai Q, Mai K, Xu W, Liufu Z, Zhang W and Cai Y Effects of dietary soybean saponins on feed intake, growth performance, digestibility and intestinal structure in juvenile Japanese flounder (Paralichthys olivaceus). Aquaculture 318, 95-100. http://www.sciencedirect.com/science/article/pii/S0044848611003772

Chung YH, Zhou M, Holtshausen L, Alexander TW, McAllister TA, Guan LL, Oba M and Beauchemin KA A fibrolytic enzyme additive for lactating Holstein cow diets: Ruminal fermentation, rumen microbial populations, and enteric methane emissions. Journal of Dairy Science 95, 1419-27. http://www.sciencedirect.com/science/article/pii/S0022030212000999

Coffman RL, Sher A and Seder RA Vaccine Adjuvants: Putting Innate Immunity to Work. Immunity 33, 492-503. http://www.sciencedirect.com/science/article/pii/S1074761310003626

Costa CTC, Bevilaqua CML, Morais SM, Camurça-Vasconcelos ALF, Maciel MV, Braga RR and Oliveira LMB Anthelmintic activity of Cocos nucifera L. on intestinal nematodes of mice. Research in Veterinary Science 88, 101-3. http://www.sciencedirect.com/science/article/pii/S0034528809001350

Costello CE Application of tandem mass spectral approaches to structural determinations of saponins. Saponins used in food and agriculture /, 317-30.

Cox RJ, Pedersen G, Madhun AS, Svindland S, Sævik M, Breakwell L, Hoschler K, Willemsen M, Campitelli L, Nøstbakken JK, Weverling GJ, Klap J, McCullough KC, Zambon M, Kompier R and Sjursen H Evaluation of a virosomal H5N1 vaccine formulated with Matrix M™ adjuvant in a phase I clinical trial. Vaccine 29, 8049-59. http://www.sciencedirect.com/science/article/pii/S0264410X11012837

Cranage MP, Fraser CA, Cope A, McKay PF, Seaman MS, Cole T, Mahmoud AN, Hall J, Giles E, Voss G, Page M, Almond N and Shattock RJ Antibody responses after intravaginal immunisation with trimeric HIV-1CN54 clade C gp140 in Carbopol gel are augmented by systemic priming or boosting with an adjuvanted formulation. Vaccine 29, 1421-30. http://www.sciencedirect.com/science/article/pii/S0264410X1001786X

Cummings JF, Spring MD, Schwenk RJ, Ockenhouse CF, Kester KE, Polhemus ME, Walsh DS, Yoon I-K, Prosperi C, Juompan LY, Lanar DE, Krzych U, Hall BT, Ware LA, Stewart VA, Williams J, Dowler M, Nielsen RK, Hillier CJ, Giersing BK, Dubovsky F, Malkin E, Tucker K, Dubois M-C, Cohen JD, Ballou WR and Jr DGH Recombinant Liver Stage Antigen-1 (LSA-1) formulated with AS01 or AS02 is safe, elicits high titer antibody and induces IFN-Îł/IL-2 CD4+ T cells but does not protect against experimental Plasmodium falciparum infection. Vaccine 28, 5135-44. http://www.sciencedirect.com/science/article/pii/S0264410X09012316

Cunha IALd, Zulpo DL, Bogado ALG, de Barros LD, Taroda A, Igarashi M, Navarro IT and Garcia JoL Humoral and cellular immune responses in pigs immunized intranasally with crude rhoptry proteins of Toxoplasma gondii plus Quil-A. Veterinary Parasitology 186, 216-21. http://www.sciencedirect.com/science/article/pii/S0304401711007667

Dagostin S, SchÄrer H-J, Pertot I and Tamm L Are there alternatives to copper for controlling grapevine downy mildew in organic viticulture? Crop Protection 30, 776-88. http://www.sciencedirect.com/science/article/pii/S026121941100086X

Dai X, Shi X, Yin Q, Ding H and Qiao Y Multiscale study on the interaction mechanism between ginsenoside biosurfactant and saikosaponin a. Journal of Colloid and Interface Science 396, 165-72. http://www.sciencedirect.com/science/article/pii/S0021979713000313

Das BK, Pradhan J, Sahu S, Marhual NP, Mishra BK and Eknath AE Microcystis aeruginosa (Kütz) incorporated diets increase immunity and survival of Indian major carp Labeo rohita (Ham.) against Aeromonas hydrophila infection. Aquaculture Research, n/a-n/a. http://dx.doi.org/10.1111/j.1365-2109.2012.03098.x

das Neves J, Amiji MM, Bahia MF and Sarmento B Nanotechnology-based systems for the treatment and prevention of HIV/AIDS. Advanced Drug Delivery Reviews 62, 458-77. http://www.sciencedirect.com/science/article/pii/S0169409X09003585

Davis BL, Fraser JN, Burkey TE, Skjolaas KA, Dritz SS, Johnson BJ and Minton JE Oral inoculation with Salmonella enterica serovar Typhimurium or Choleraesuis promotes divergent responses in the somatotropic growth axis of swine. J Anim Sci 88, 1642-8. http://jas.fass.org/cgi/content/abstract/88/5/1642

de Costa F, Yendo ACA, Fleck JD, Gosmann G and Fett-Neto AG Accumulation of a bioactive triterpene saponin fraction of Quillaja brasiliensis leaves is associated with abiotic and biotic stresses. Plant Physiology and Biochemistry 66, 56-62. http://www.sciencedirect.com/science/article/pii/S0981942813000442

De Geyter E, Smagghe G, Rahbe Y and Geelen D Triterpene saponins of Quillaja saponaria show strong aphicidal and deterrent activity against the pea aphid Acyrthosiphon pisum. Pest Manag Sci 68, 164-9.

De Geyter E, Smagghe G, Rahbé Y and Geelen D Triterpene saponins of Quillaja saponaria show strong aphicidal and deterrent activity against the pea aphid Acyrthosiphon pisum. Pest Management Science 68, 164-9. http://dx.doi.org/10.1002/ps.2235

De Geyter E, Swevers L, Caccia S, Geelen D and Smagghe G Saponins show high entomotoxicity by cell membrane permeation in Lepidoptera. Pest Management Science, n/a-n/a. http://dx.doi.org/10.1002/ps.3284

De Geyter E, Swevers L, Soin T, Geelen D and Smagghe G Saponins do not affect the ecdysteroid receptor complex but cause membrane permeation in insect culture cell lines. Journal of Insect Physiology. http://www.sciencedirect.com/science/article/pii/S0022191011002708

De Temmerman M-L, Rejman J, Demeester J, Irvine DJ, Gander B and De Smedt SC Particulate vaccines: on the quest for optimal delivery and immune response. Drug Discovery Today 16, 569-82. http://www.sciencedirect.com/science/article/pii/S1359644611001334

Del Giudice G and Rappuoli R Adjuvants and Subunit Vaccines. In ‘Topley & Wilson’s Microbiology and Microbial Infections’. (Ed.^(Eds  pp. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9780470688618.taw0126

den Brok MH, Nierkens S, Wagenaars JA, Ruers TJ, Schrier CC, Rijke EO and Adema GJ Saponin-based adjuvants create a highly effective anti-tumor vaccine when combined with in situ tumor destruction. Vaccine 30, 737-44. http://www.sciencedirect.com/science/article/pii/S0264410X11018767

Dendouga N, Fochesato M, Lockman L, Mossman S and Giannini SL Cell-mediated immune responses to a varicella-zoster virus glycoprotein E vaccine using both a TLR agonist and QS21 in mice. Vaccine 30, 3126-35. http://www.sciencedirect.com/science/article/pii/S0264410X12001612

Deng JM, Mai KS, Ai QH, Zhang WB, Wang XJ, Xu W, Liufu ZG, Cai YH and Chen W Effects of antinutritional factors on plasma lipoprotein levels in Japanese flounder Paralichthys olivaceus. Journal of Fish Biology 80, 286-300. http://dx.doi.org/10.1111/j.1095-8649.2011.03170.x

Deymeh H, Shadizadeh SR and Motafakkerfard R Experimental investigation of Seidlitzia rosmarinus effect on oil–water interfacial tension: Usable for chemical enhanced oil recovery. Scientia Iranica. http://www.sciencedirect.com/science/article/pii/S1026309812001459

Deymeh H, Shadizadeh SR and Motafakkerfard R Experimental investigation of Seidlitzia rosmarinus effect on oil–water interfacial tension: Usable for chemical enhanced oil recovery. Scientia Iranica 19, 1661-4. http://www.sciencedirect.com/science/article/pii/S1026309812001459

Dodd RS and Rafii ZA Ecogeographic variation in seed fatty acids of Austrocedrus chilensis. Biochemical Systematics and Ecology 23, 825-33. http://www.sciencedirect.com/science/article/pii/0305197895000623

Donato P, Cacciola F, Tranchida PQ, Dugo P and Mondello L Mass spectrometry detection in comprehensive liquid chromatography: Basic concepts, instrumental aspects, applications and trends. Mass Spectrometry Reviews, n/a-n/a. http://dx.doi.org/10.1002/mas.20353

Dubensky Jr TW and Reed SG Adjuvants for cancer vaccines. Seminars in Immunology 22, 155-61. http://www.sciencedirect.com/science/article/pii/S1044532310000485

Eliasson DG, Helgeby A, SchÖn K, Nygren C, El-Bakkouri K, Fiers W, Saelens X, LÖvgren KB, NystrÖm I and Lycke NY A novel non-toxic combined CTA1-DD and ISCOMS adjuvant vector for effective mucosal immunization against influenza virus. Vaccine 29, 3951-61. http://www.sciencedirect.com/science/article/pii/S0264410X1100483X

Eppstein DA, Byars NE and Allison AC New adjuvants for vaccines containing purified protein antigens. Advanced Drug Delivery Reviews 4, 233-53. http://www.sciencedirect.com/science/article/pii/0169409X89900203

Fernando GJP, Chen X, Primiero CA, Yukiko SR, Fairmaid EJ, Corbett HJ, Frazer IH, Brown LE and Kendall MAF Nanopatch targeted delivery of both antigen and adjuvant to skin synergistically drives enhanced antibody responses. Journal of Controlled Release 159, 215-21. http://www.sciencedirect.com/science/article/pii/S0168365912000351

Fidan AF and Dündar Y The effects of Yucca schidigera and Quillaja saponaria on DNA damage, protein oxidation, lipid peroxidation, and some biochemical parameters in streptozotocin-induced diabetic rats. Journal of Diabetes and its Complications 22, 348-56. http://www.sciencedirect.com/science/article/pii/S1056872707001444

Fink-Gremmels J Defense mechanisms against toxic phytochemicals in the diet of domestic animals. Molecular Nutrition & Food Research 54, 249-58. http://dx.doi.org/10.1002/mnfr.200900361

Fischer MJ, Pensec F, Demangeat G, Farine S, Chong J, Ramirez-Suero M, Mazet F and Bertsch C Impact of Quillaja saponaria saponins on grapevine ecosystem organisms. Antonie Van Leeuwenhoek 100, 197-206.

Foged C, Hansen J and Agger EM License to kill: Formulation requirements for optimal priming of CD8+ CTL responses with particulate vaccine delivery systems. European Journal of Pharmaceutical Sciences 45, 482-91. http://www.sciencedirect.com/science/article/pii/S0928098711002909

Freches D, Romano M, Korf H, Renauld J-C, Van Snick J, Uyttenhove C and Huygen K Increased Pulmonary Tumor Necrosis Factor Alpha, Interleukin-6 (IL-6), and IL-17A Responses Compensate for Decreased Gamma Interferon Production in Anti-IL-12 Autovaccine-Treated, Mycobacterium bovis BCG-Vaccinated Mice. Clin. Vaccine Immunol. 18, 95-104. http://cvi.asm.org/cgi/content/abstract/18/1/95

Fuentes-Castillo T, Miranda A, Rivera-Hutinel A, Smith-RamÍrez C and Holmgren M Nucleated regeneration of semiarid sclerophyllous forests close to remnant vegetation. Forest Ecology and Management 274, 38-47. http://www.sciencedirect.com/science/article/pii/S0378112712000953

G. Peixoto MP, Treter J, de Resende PE, da Silveira NP, Ortega GG, Lawrence MJ and Dreiss CA Wormlike micellar aggregates of saponins from Ilex paraguariensis A. St. Hil. (mate): A characterisation by cryo-TEM, rheology, light scattering and small-angle neutron scattering. Journal of Pharmaceutical Sciences 100, 536-46. http://dx.doi.org/10.1002/jps.22283

Gaete-GarretÓn L, Vargas-HernÁndez Y, Cares-Pacheco MaG, Sainz J and AlarcÓn J Ultrasonically enhanced extraction of bioactive principles from Quillaja Saponaria Molina. Ultrasonics 51, 581-5. http://www.sciencedirect.com/science/article/pii/S0041624X10001988

Gaete-Garreton L, Vargas-Hernandez Y, Cares-Pacheco MG, Sainz J and Alarcon J Ultrasonically enhanced extraction of bioactive principles from Quillaja Saponaria Molina. Ultrasonics 51, 581-5.

Gane E Hepatitis B immunoglobulin immunoprophylaxis for hepatitis B: High, low, or no dose?1. Liver Transplantation 16, S36-S9. http://dx.doi.org/10.1002/lt.22151

Garçon N, Hem S and Friede M 5 - Evolution of adjuvants across the centuries. In ‘Vaccines (Sixth Edition)’. (Ed.^(Eds  pp. 58-70. (W.B. Saunders: London). http://www.sciencedirect.com/science/article/pii/B9781455700905000203

Garçon N, Leroux-Roels G and Cheng W-F Vaccine adjuvants. Perspectives in Vaccinology 1, 89-113. http://www.sciencedirect.com/science/article/pii/S2210762211000052

GarcÍa-GonzÁlez R, GonzÁlez JS and LÓpez S Decrease of ruminal methane production in Rusitec fermenters through the addition of plant material from rhubarb (Rheum spp.) and alder buckthorn (Frangula alnus). Journal of Dairy Science 93, 3755-63. http://www.sciencedirect.com/science/article/pii/S0022030210003954

Gebru E, Lee JS, Son JC, Yang SY, Shin SA, Kim B, Kim MK and Park SC Effect of probiotic-, bacteriophage-, or organic acid-supplemented feeds or fermented soybean meal on the growth performance, acute-phase response, and bacterial shedding of grower pigs challenged with Salmonella enterica serotype Typhimurium. J Anim Sci 88, 3880-6. http://jas.fass.org/cgi/content/abstract/88/12/3880

Gentil F, Bargieri DY, Leite JA, Françoso KtS, Patricio MBM, EspÍndola NM, Vaz AJ, Palatnik-de-Sousa CB, Rodrigues MM, Costa FTM and Soares IS A recombinant vaccine based on domain II of Plasmodium vivax Apical Membrane Antigen 1 induces high antibody titres in mice. Vaccine 28, 6183-90. http://www.sciencedirect.com/science/article/pii/S0264410X10010005

Gertsch Jr, Viveros-Paredes JM and Taylor P Plant immunostimulants—Scientific paradigm or myth? Journal of Ethnopharmacology 136, 385-91. http://www.sciencedirect.com/science/article/pii/S0378874110004605

Ghazarian H, Idoni B and Oppenheimer SB A glycobiology review: Carbohydrates, lectins and implications in cancer therapeutics. Acta Histochemica 113, 236-47. http://www.sciencedirect.com/science/article/pii/S0065128110000267

Giannattasio G, Ohta S, Boyce JR, Xing W, Balestrieri B and Boyce JA The Purinergic G Protein-Coupled Receptor 6 Inhibits Effector T Cell Activation in Allergic Pulmonary Inflammation. J. Immunol. 187, 1486-95. http://www.jimmunol.org/cgi/content/abstract/187/3/1486

Gilabert-Oriol R, Mergel K, Thakur M, von Mallinckrodt B, Melzig MF, Fuchs H and Weng A Real-time analysis of membrane permeabilizing effects of oleanane saponins. Bioorganic & Medicinal Chemistry 21, 2387-95. http://www.sciencedirect.com/science/article/pii/S0968089613001004

Giner M, Avilla Js, De Zutter N, Ameye M, Balcells M and Smagghe G Insecticidal and repellent action of allyl esters against Acyrthosiphon pisum (Hemiptera: Aphididae) and Tribolium castaneum (Coleoptera: Tenebrionidae). Industrial Crops and Products 47, 63-8. http://www.sciencedirect.com/science/article/pii/S092666901300099X

Goiri I, Oregui LM and Garcia-Rodriguez A Use of chitosans to modulate ruminal fermentation of a 50:50 forage-to-concentrate diet in sheep. J Anim Sci 88, 749-55. http://jas.fass.org/cgi/content/abstract/88/2/749

Gómez-González S, Torres-Díaz C, Valencia G, Torres-Morales P, Cavieres LA and Pausas JG Anthropogenic fires increase alien and native annual species in the Chilean coastal matorral. Diversity and Distributions 17, 58-67. http://dx.doi.org/10.1111/j.1472-4642.2010.00728.x

GonzÁlez-GÓmez PL, Bozinovic F and VÁsquez RA Elements of episodic-like memory in free-living hummingbirds, energetic consequences. Animal Behaviour 81, 1257-62. http://www.sciencedirect.com/science/article/pii/S0003347211001114

Gupta A, Khajuria A, Singh J, Singh S, Suri KA and Qazi GN Immunological adjuvant effect of Boswellia serrata (BOS 2000) on specific antibody and cellular response to ovalbumin in mice. International Immunopharmacology 11, 968-75. http://www.sciencedirect.com/science/article/pii/S1567576911001020

Hamshou M, Van Damme EJM, Caccia S, Cappelle K, Vandenborre G, Ghesquière B, Gevaert K and Smagghe G High entomotoxicity and mechanism of the fungal GalNAc/Gal-specific Rhizoctonia solani lectin in pest insects. Journal of Insect Physiology 59, 295-305. http://www.sciencedirect.com/science/article/pii/S0022191012003009

Harvey DJ Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: An update for 2007–2008. Mass Spectrometry Reviews 31, 183-311. http://dx.doi.org/10.1002/mas.20333

Hassan SA, Moussa EA and Abbott LC The effect of methylmercury exposure on early central nervous system development in the zebrafish (Danio rerio) embryo. Journal of Applied Toxicology, n/a-n/a. http://dx.doi.org/10.1002/jat.1675

Hassan SM, Haq AU, Byrd JA, Berhow MA, Cartwright AL and Bailey CA Haemolytic and antimicrobial activities of saponin-rich extracts from guar meal. Food Chemistry 119, 600-5. http://www.sciencedirect.com/science/article/pii/S0308814609008747

Hedayat M, Netea MG and Rezaei N Targeting of Toll-like receptors: a decade of progress in combating infectious diseases. The Lancet Infectious Diseases 11, 702-12. http://www.sciencedirect.com/science/article/pii/S1473309911700998

Hedayat M, Takeda K and Rezaei N Prophylactic and therapeutic implications of toll-like receptor ligands. Medicinal Research Reviews 32, 294-325. http://dx.doi.org/10.1002/med.20214

Heidarian Miri V, Tyagi AK, Ebrahimi SH and Mohini M Effect of cumin (Cuminum cyminum) seed extract on milk fatty acid profile and methane emission in lactating goat. Small Ruminant Research. http://www.sciencedirect.com/science/article/pii/S092144881300028X

Heldens JGM, Pouwels HGW, Derks CGG, Van de Zande SMA and Hoeijmakers MJH Duration of immunity induced by an equine influenza and tetanus combination vaccine formulation adjuvanted with ISCOM-Matrix. Vaccine 28, 6989-96. http://www.sciencedirect.com/science/article/pii/S0264410X10011886

Hossain E, Rawani A, Chandra G, Mandal SC and Gupta JK Larvicidal activity of Dregea volubilis and Bombax malabaricum leaf extracts against the filarial vector Culex quinquefasciatus. Asian Pacific Journal of Tropical Medicine 4, 436-41. http://www.sciencedirect.com/science/article/pii/S1995764511601211

Hsu C-H, Hung S-C, Wu C-Y and Wong C-H Auf dem Weg zur automatisierten Oligosaccharid- Synthese. Angewandte Chemie 123, 12076-129. http://dx.doi.org/10.1002/ange.201100125

Hsu C-H, Hung S-C, Wu C-Y and Wong C-H Toward Automated Oligosaccharide Synthesis. Angewandte Chemie International Edition 50, 11872-923. http://dx.doi.org/10.1002/anie.201100125

Hu K, Berenjian S, Larsson R, Gullbo J, Nygren P, Lovgren T and Morein B Nanoparticulate Quillaja saponin induces apoptosis in human leukemia cell lines with a high therapeutic index. Int J Nanomedicine 5, 51-62.

Huang S-s, Han Y-p, Li C-s, Tian J, Li W-b and Wang J-a Identification of QTLs Associated with Total Soyasaponin Content in Soybean (Glycine max (L.) Merr.). Journal of Integrative Agriculture 11, 1976-84. http://www.sciencedirect.com/science/article/pii/S2095311912604547

Jahangiri A, Rasooli I, Gargari SLM, Owlia P, Rahbar MR, Amani J and Khalili S An in silico DNA vaccine against Listeria monocytogenes. Vaccine 29, 6948-58. http://www.sciencedirect.com/science/article/pii/S0264410X11010723

Jensen TL, Provenza FD and Villalba JJ Influence of diet sequence on intake of foods containing ergotamine d tartrate, tannins and saponins by sheep. Applied Animal Behaviour Science 144, 57-62. http://www.sciencedirect.com/science/article/pii/S0168159112003693

JimÉnez-Peralta FS, Salem AZM, Mejia-HernÁndez P, GonzÁlez-Ronquillo M, AlbarrÁn-Portillo B, Rojo-Rubio R and Tinoco-Jaramillo JL Influence of individual and mixed extracts of two tree species on in vitro gas production kinetics of a high concentrate diet fed to growing lambs. Livestock Science 136, 192-200. http://www.sciencedirect.com/science/article/pii/S187114131000524X

Joshi MD, Unger WJ, Storm G, van Kooyk Y and Mastrobattista E Targeting tumor antigens to dendritic cells using particulate carriers. Journal of Controlled Release 161, 25-37. http://www.sciencedirect.com/science/article/pii/S0168365912003380

Kamalakannan S, Murugan K and Barnard DR Toxicity of Acalypha indica (Euphorbiaceae) and Achyranthes aspera (Amaranthaceae) leaf extracts to Aedes aegypti (Diptera: Culicidae). Journal of Asia-Pacific Entomology 14, 41-5. http://www.sciencedirect.com/science/article/pii/S122686151000124X

Kayani MZ, Mukhtar T and Hussain MA Evaluation of nematicidal effects of Cannabis sativa L. and Zanthoxylum alatum Roxb. against root-knot nematodes, Meloidogyne incognita. Crop Protection 39, 52-6. http://www.sciencedirect.com/science/article/pii/S0261219412000920

Kensil CR, Soltysik S, Wheeler DA and Wu JY Structure function studies on QS-21, a unique immunological adjuvant from Quillaja saponaria. Saponins used in traditional and modern medicine /, 165-72.

Khursheed S, Anwer R, Zutshi S and Fatma T SCREENING OF PHOTOSYNTHETIC O2-EVOLVING PROKARYOTES FOR AN INSULIN-LIKE ANTIGEN1. Journal of Phycology 48, 243-5. http://dx.doi.org/10.1111/j.1529-8817.2011.01086.x

Kiliç E, Font J, Puig R, Çolak S and Çelik D Chromium recovery from tannery sludge with saponin and oxidative remediation. Journal of Hazardous Materials 185, 456-62. http://www.sciencedirect.com/science/article/pii/S030438941001215X

Kim S-H, Seo K-W, Kim J, Lee K-Y and Jang Y-S The M Cell-Targeting Ligand Promotes Antigen Delivery and Induces Antigen-Specific Immune Responses in Mucosal Vaccination. J. Immunol. 185, 5787-95. http://www.jimmunol.org/cgi/content/abstract/185/10/5787

Krogdahl Ĺ, Penn M, Thorsen J, Refstie S and Bakke AM Important antinutrients in plant feedstuffs for aquaculture: an update on recent findings regarding responses in salmonids. Aquaculture Research 41, 333-44. http://dx.doi.org/10.1111/j.1365-2109.2009.02426.x

Kushwaha S, Roy S, Maity R, Mallick A, Soni VK, Singh PK, Chaurasiya ND, Sangwan RS, Misra-Bhattacharya S and Mandal C Chemotypical variations in Withania somnifera lead to differentially modulated immune response in BALB/c mice. Vaccine 30, 1083-93. http://www.sciencedirect.com/science/article/pii/S0264410X11019542

Labriola L and Jadoul M The decades-long fight against HBV transmission to dialysis patients: slow but definite progress. Nephrol. Dial. Transplant. 25, 2047-9. http://ndt.oxfordjournals.org

Lee S-H, Lillehoj HS, Jang SI, Lee K-W, Yancey RJ and Dominowski P The effects of a novel adjuvant complex/Eimeria profilin vaccine on the intestinal host immune response against live E. acervulina challenge infection. Vaccine 28, 6498-504. http://www.sciencedirect.com/science/article/pii/S0264410X10009588

Lepenies B, Yin J and Seeberger PH Applications of synthetic carbohydrates to chemical biology. Current Opinion in Chemical Biology 14, 404-11. http://www.sciencedirect.com/science/article/pii/S1367593110000219

Leroux-Roels G Unmet needs in modern vaccinology: Adjuvants to improve the immune response. Vaccine 28, Supplement 3, C25-C36. http://www.sciencedirect.com/science/article/pii/S0264410X10010042

Leroux-Roels I, Forgus S, De Boever F, Clement F, Demoitié M-A, Mettens P, Moris P, Ledent E, Leroux-Roels G and Ofori-Anyinam O Improved CD4+ T cell responses to Mycobacterium tuberculosis in PPD-negative adults by M72/AS01 as compared to the M72/AS02 and Mtb72F/AS02 tuberculosis candidate vaccine formulations: A randomized trial. Vaccine. http://www.sciencedirect.com/science/article/pii/S0264410X12007396

Leroux-Roels I, Forgus S, De Boever F, Clement Fdr, DemoitiÉ M-A, Mettens P, Moris P, Ledent E, Leroux-Roels G and Ofori-Anyinam O Improved CD4+ T cell responses to Mycobacterium tuberculosis in PPD-negative adults by M72/AS01 as compared to the M72/AS02 and Mtb72F/AS02 tuberculosis candidate vaccine formulations: A randomized trial. Vaccine. http://www.sciencedirect.com/science/article/pii/S0264410X12007396

Leroux-Roels I, Koutsoukos M, Clement Fdr, Steyaert S, Janssens M, Bourguignon P, Cohen K, Altfeld M, Vandepapelière P, Pedneault L, McNally L, Leroux-Roels G and Voss G Strong and persistent CD4+ T-cell response in healthy adults immunized with a candidate HIV-1 vaccine containing gp120, Nef and Tat antigens formulated in three Adjuvant Systems. Vaccine 28, 7016-24. http://www.sciencedirect.com/science/article/pii/S0264410X10011801

Leroux-Roels I, Leroux-Roels G, Ofori-Anyinam O, Moris P, De Kock E, Clement F, Dubois M-C, Koutsoukos M, Demoitie M-A, Cohen J and Ballou WR Evaluation of the Safety and Immunogenicity of Two Antigen Concentrations of the Mtb72F/AS02A Candidate Tuberculosis Vaccine in Purified Protein Derivative-Negative Adults. Clin. Vaccine Immunol. 17, 1763-71. http://cvi.asm.org/cgi/content/abstract/17/11/1763

Levitz Stuart M and Golenbock Douglas T Beyond Empiricism: Informing Vaccine Development through Innate Immunity Research. Cell 148, 1284-92. http://www.sciencedirect.com/science/article/pii/S0092867412002115

Li D, Baert L and Uyttendaele M Inactivation of food-borne viruses using natural biochemical substances. Food Microbiology 35, 1-9. http://www.sciencedirect.com/science/article/pii/S0740002013000324

Liang X-m, Jin Y, Feng J-t and Ke Y-x Identification and Structure Elucidation of Compounds from Herbal Medicines. In ‘Traditional Herbal Medicine Research Methods’. (Ed.^(Eds  pp. 139-223. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470921340.ch4

Liang Z, Li K, Wang X, Ke Y, Jin Y and Liang X Combination of off-line two-dimensional hydrophilic interaction liquid chromatography for polar fraction and two-dimensional hydrophilic interaction liquid chromatography&#xa0;Ă—&#xa0;reversed-phase liquid chromatography for medium-polar fraction in a traditional Chinese medicine. Journal of Chromatography A 1224, 61-9. http://www.sciencedirect.com/science/article/pii/S0021967311018309

Licciardi PV and Underwood JR Plant-derived medicines: A novel class of immunological adjuvants. International Immunopharmacology 11, 390-8. http://www.sciencedirect.com/science/article/pii/S1567576910003437

Licciardi PV and Underwood JR Identification of a novel vaccine adjuvant that stimulates and maintains diphtheria toxoid immunity. Vaccine 28, 3865-73. http://www.sciencedirect.com/science/article/pii/S0264410X10002549

Lye H-S, Rahmat-Ali GR and Liong M-T Mechanisms of cholesterol removal by lactobacilli under conditions that mimic the human gastrointestinal tract. International Dairy Journal 20, 169-75. http://www.sciencedirect.com/science/article/pii/S0958694609001903

Magnusson SE, Reimer JM, Karlsson KH, Lilja L, Bengtsson KLv and Stertman L Immune enhancing properties of the novel Matrix-M™ adjuvant leads to potentiated immune responses to an influenza vaccine in mice. Vaccine 31, 1725-33. http://www.sciencedirect.com/science/article/pii/S0264410X13001072

Man S, Gao W, Zhang Y, Huang L and Liu C Chemical study and medical application of saponins as anti-cancer agents. Fitoterapia 81, 703-14. http://www.sciencedirect.com/science/article/pii/S0367326X10001346

Mazvimba MT, Yu Y, Cui Z-Q and Zhang Y Optimization and orthogonal design of an ultrasonic-assisted aqueous extraction process for extracting chlorogenic acid from dry tobacco leaves. Chinese Journal of Natural Medicines 10, 311-20. http://www.sciencedirect.com/science/article/pii/S1875536412600648

McShane H Tuberculosis vaccines: beyond bacille Calmette-Guerin. Phil Trans R Soc B 366, 2782-9. http://rstb.royalsocietypublishing.org/cgi/content/abstract/366/1579/2782

Meale SJ, Chaves AV, Hannah MC, Williams SRO, Hume DE, Mace WJ and Moate PJ Comparison of wild type, AR1 and AR37 endophyte infected perennial ryegrass on in vitro methanogenesis. Animal Feed Science and Technology 180, 10-7. http://www.sciencedirect.com/science/article/pii/S0377840112004002

Moate PJ, Williams SRO, Hannah MC, Eckard RJ, Auldist MJ, Ribaux BE, Jacobs JL and Wales WJ Effects of feeding algal meal high in docosahexaenoic acid on feed intake, milk production, and methane emissions in dairy cows. Journal of Dairy Science. http://www.sciencedirect.com/science/article/pii/S0022030213001975

Moreno-Mendieta SA, Rocha-Zavaleta L and Rodriguez-Sanoja R Adjuvants in tuberculosis vaccine development. FEMS Immunology & Medical Microbiology 58, 75-84. http://dx.doi.org/10.1111/j.1574-695X.2009.00629.x

Mukhopadhyay P, Chakraborty S, Ponnusamy MP, Lakshmanan I, Jain M and Batra SK Mucins in the pathogenesis of breast cancer: Implications in diagnosis, prognosis and therapy. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1815, 224-40. http://www.sciencedirect.com/science/article/pii/S0304419X11000023

Mutiso JM, Macharia JC and Gicheru MM A review of adjuvants for Leishmania vaccine candidates. Journal of Biomedical Research 24, 16-25. http://www.sciencedirect.com/science/article/pii/S1674830110600048

Naarding MA, Falkowska E, Xiao H and Dragic T Hepatitis C virus soluble E2 in combination with QuilA and CpG ODN induces neutralizing antibodies in mice. Vaccine 29, 2910-7. http://www.sciencedirect.com/science/article/pii/S0264410X11002106

Nagill R and Kaur S Vaccine candidates for leishmaniasis: A review. International Immunopharmacology 11, 1464-88. http://www.sciencedirect.com/science/article/pii/S1567576911002190

Nahuelhual L, Carmona A, Lara A, EcheverrÍa C and GonzÁlez ME Land-cover change to forest plantations: Proximate causes and implications for the landscape in south-central Chile. Landscape and Urban Planning 107, 12-20. http://www.sciencedirect.com/science/article/pii/S0169204612001302

Nalbantsoy A, Nesil T, Erden Si, Çalış Äh and Bedir E Adjuvant effects of Astragalus saponins Macrophyllosaponin B and Astragaloside VII. Journal of Ethnopharmacology 134, 897-903. http://www.sciencedirect.com/science/article/pii/S0378874111000699

Nasri S and Ben Salem H Effect of oral administration of Agave americana or Quillaja saponaria extracts on digestion and growth of Barbarine female lamb. Livestock Science 147, 59-65. http://www.sciencedirect.com/science/article/pii/S1871141312001321

Nasri S, Luciano G, Vasta V, Aouadi D, Priolo A, Makkar HPS and Ben Salem H Effect of Quillaja saponaria dietary administration on colour, oxidative stability and volatile profile of muscle longissimus dorsi of Barbarine lamb. Meat Science. http://www.sciencedirect.com/science/article/pii/S0309174012002124

Nasri Sd, Ben Salem H, Vasta V, Abidi S, Makkar HPS and Priolo A Effect of increasing levels of Quillaja saponaria on digestion, growth and meat quality of Barbarine lamb. Animal Feed Science and Technology 164, 71-8. http://www.sciencedirect.com/science/article/pii/S0377840110004256

Newton AC, EcheverrÍa C, Cantarello E and Bolados G Projecting impacts of human disturbances to inform conservation planning and management in a dryland forest landscape. Biological Conservation 144, 1949-60. http://www.sciencedirect.com/science/article/pii/S0006320711001212

Nicholls EF, Madera L and Hancock REW Immunomodulators as adjuvants for vaccines and antimicrobial therapy. Annals of the New York Academy of Sciences 1213, 46-61. http://dx.doi.org/10.1111/j.1749-6632.2010.05787.x

Nico D, Borges RM, BrandĂŁo LM, FeijÓ DF, Gomes DC, Palatnik M, Rodrigues MM, da Silva AJR and Palatnik-de-Sousa CB The adjuvanticity of Chiococca alba saponins increases with the length and hydrophilicity of their sugar chains. Vaccine 30, 3169-79. http://www.sciencedirect.com/science/article/pii/S0264410X12003532

Oka Y Mechanisms of nematode suppression by organic soil amendments—A review. Applied Soil Ecology 44, 101-15. http://www.sciencedirect.com/science/article/pii/S0929139309001942

Oliveira-Nascimento L, Caricati ATP, Abdulack-Lopes F, Neves LCM, Caricati CP, Penna TCV and Stephano MA Bacillus atrophaeus inactivated spores as a potential adjuvant for veterinary rabies vaccine. Vaccine 30, 3351-4. http://www.sciencedirect.com/science/article/pii/S0264410X12003921

Owens J, Provenza FD, Wiedmeier RD and Villalba JJ Influence of saponins and tannins on intake and nutrient digestion of alkaloid-containing foods. Journal of the Science of Food and Agriculture, n/a-n/a. http://dx.doi.org/10.1002/jsfa.5643

Pan L, Lezama-Davila CM, Isaac-Marquez AP, Calomeni EP, Fuchs JR, Satoskar AR and Kinghorn AD Sterols with antileishmanial activity isolated from the roots of Pentalinon andrieuxii. Phytochemistry. http://www.sciencedirect.com/science/article/pii/S0031942212002890

Pandey RS, Babbar AK, Kaul A, Mishra AK and Dixit VK Evaluation of ISCOM matrices clearance from rabbit nasal cavity by gamma scintigraphy. International Journal of Pharmaceutics 398, 231-6. http://www.sciencedirect.com/science/article/pii/S0378517310005788

Papadopoulou G, Karagouni E and Dotsika E ISCOMs vaccine against experimental leishmaniasis. Vaccine 16, 885-92. http://www.sciencedirect.com/science/article/pii/S0264410X97003083

Parida SK and Kaufmann SHE Novel tuberculosis vaccines on the horizon. Current Opinion in Immunology 22, 374-84. http://www.sciencedirect.com/science/article/pii/S0952791510000701

Patil SV, Salunke BK, Patil CD, Salunkhe RB, Gavit P and Maheshwari VL Potential of extracts of the tropical plant Balanites aegyptiaca (L) Del. (Balanitaceae) to control the mealy bug, Maconellicoccus hirsutus (Homoptera: Pseudococcidae). Crop protection. 29, 1293-6. http://dx.doi.org/10.1016/j.cropro.2010.05.016

Patra AK Meta-analyses of effects of phytochemicals on digestibility and rumen fermentation characteristics associated with methanogenesis. Journal of the Science of Food and Agriculture 90, 2700-8. http://dx.doi.org/10.1002/jsfa.4143

Patra AK and Saxena J A new perspective on the use of plant secondary metabolites to inhibit methanogenesis in the rumen. Phytochemistry 71, 1198-222. http://www.sciencedirect.com/science/article/pii/S0031942210001858

Payne SE, Kotze AC, Durmic Z and Vercoe PE Australian plants show anthelmintic activity toward equine cyathostomins in vitro. Veterinary Parasitology. http://www.sciencedirect.com/science/article/pii/S030440171300037X

Pedersen G, Major D, Roseby S, Wood J, Madhun AS and Cox RJ Matrix-M adjuvanted virosomal H5N1 vaccine confers protection against lethal viral challenge in a murine model. Influenza and Other Respiratory Viruses 5, 426-37. http://dx.doi.org/10.1111/j.1750-2659.2011.00256.x

Pedersen Jan S, Oliveira Cristiano LP, HÜbschmann Henriette B, Arleth L, Manniche Sr, Kirkby N and Nielsen Hanne Mr Structure of Immune Stimulating Complex Matrices and Immune Stimulating Complexes in Suspension Determined by Small-Angle X-Ray Scattering. Biophysical Journal 102, 2372-80. http://www.sciencedirect.com/science/article/pii/S0006349512004134

Peixoto MPG, Kaiser S, Verza SG, de Resende PE, Treter J, Pavei C, Borré GL and Ortega GG LC-UV Assay Method and UPLC/Q-TOF-MS Characterisation of Saponins from Ilex Paraguariensis A. St. Hil. (Mate) Unripe Fruits. Phytochemical Analysis, n/a-n/a. http://dx.doi.org/10.1002/pca.1374

Pelosi A, Shepherd R and Walmsley AM Delivery of plant-made vaccines and therapeutics. Biotechnology Advances 30, 440-8. http://www.sciencedirect.com/science/article/pii/S0734975011001285

Plumptre CD, Ogunniyi AD and Paton JC Polyhistidine triad proteins of pathogenic streptococci. Trends in Microbiology. http://www.sciencedirect.com/science/article/pii/S0966842X1200114X

Prabakaran D and Ashokkumar N Protective effect of esculetin on hyperglycemia-mediated oxidative damage in the hepatic and renal tissues of experimental diabetic rats. Biochimie 95, 366-73. http://www.sciencedirect.com/science/article/pii/S0300908412004087

Qiu Y-L, Li L, Wang B, Xue J-Y, Hendry TA, Li R-Q, Brown JW, Liu Y, Hudson GT and Chen Z-D Angiosperm phylogeny inferred from sequences of four mitochondrial genes. Journal of Systematics and Evolution 48, 391-425. http://dx.doi.org/10.1111/j.1759-6831.2010.00097.x

Quispe-Fuentes I, Vega-GÁLvez A, Miranda M, Lemus-Mondaca R, Lozano M and Ah-Hen K A KINETIC APPROACH TO SAPONIN EXTRACTION DURING WASHING OF QUINOA (CHENOPODIUM QUINOA WILLD.) SEEDS. Journal of Food Process Engineering, no-no. http://dx.doi.org/10.1111/j.1745-4530.2012.00673.x

Ragupathi G, Damani P, Deng K, Adams MM, Hang J, George C, Livingston PO and Gin DY Preclinical evaluation of the synthetic adjuvant SQS-21 and its constituent isomeric saponins. Vaccine 28, 4260-7.

Ragupathi G, Gardner JR, Livingston PO and Gin DY Natural and synthetic saponin adjuvant QS-21 for vaccines against cancer. Expert Rev Vaccines 10, 463-70.

Rajakumar G and Abdul Rahuman A Larvicidal activity of synthesized silver nanoparticles using Eclipta prostrata leaf extract against filariasis and malaria vectors. Acta Tropica 118, 196-203. http://www.sciencedirect.com/science/article/pii/S0001706X1100060X

Ramya R and Sangaranarayanan MV Polypyrrole microfibres synthesized with Quillaja Saponin for sensing of catechol. Sensors and Actuators B: Chemical. http://www.sciencedirect.com/science/article/pii/S0925400512004960

RÍos J-L Effects of triterpenes on the immune system. Journal of Ethnopharmacology 128, 1-14. http://www.sciencedirect.com/science/article/pii/S0378874110000255

Reid S and Armesto JJ Interaction dynamics of avian frugivores and plants in a Chilean Mediterranean shrubland. Journal of Arid Environments 75, 221-30. http://www.sciencedirect.com/science/article/pii/S0140196310002685

Retamal PM Nutritional Management of the Prepartum Dairy Cow. In ‘Dairy Production Medicine’. (Ed.^(Eds  pp. 7-17. (Blackwell Publishing Ltd.). http://dx.doi.org/10.1002/9780470960554.ch2

Rey-Ladino J, Ross AG, Cripps AW, McManus DP and Quinn R Natural products and the search for novel vaccine adjuvants. Vaccine 29, 6464-71. http://www.sciencedirect.com/science/article/pii/S0264410X11010735

Rodríguez R and Fondevila M Effect of saponins from Enterolobium cyclocarpum on in vitro microbial fermentation of the tropical grass Pennisetum purpureum. Journal of Animal Physiology and Animal Nutrition, no-no. http://dx.doi.org/10.1111/j.1439-0396.2011.01161.x

Rodriguez-Diaz M, Delporte C, Cartagena C, Cassels BK, Gonzalez P, Silva X, Leon F and Wessjohann LA Topical anti-inflammatory activity of quillaic acid from Quillaja saponaria Mol. and some derivatives. J Pharm Pharmacol 63, 718-24.

Rodríguez-Díaz M, Delporte C, Cartagena C, Cassels BK, González P, Silva X, León F and Wessjohann LA Topical anti-inflammatory activity of quillaic acid from Quillaja saponaria Mol. and some derivatives. Journal of Pharmacy and Pharmacology 63, 718-24. http://dx.doi.org/10.1111/j.2042-7158.2011.01263.x

Rojo-VÁzquez FA, Meana A, ValcÁrcel F and MartÍnez-Valladares M Update on trematode infections in sheep. Veterinary Parasitology 189, 15-38. http://www.sciencedirect.com/science/article/pii/S0304401712001537

Rojo-Vázquez FA, Meana A, Valcárcel F and Martínez-Valladares M Update on trematode infections in sheep. Veterinary Parasitology. http://www.sciencedirect.com/science/article/pii/S0304401712001537

Roner MR, Tam KI and Kiesling-Barrager M Prevention of rotavirus infections in vitro with aqueous extracts of Quillaja Saponaria Molina. Future Med Chem 2, 1083-97.

Rubio-Moraga Ăn, Gerwig GJ, Castro-DÍaz N, Jimeno ML, Escribano J, FernÁndez J-A and Kamerling JP Triterpenoid saponins from corms of Crocus sativus: Localization, extraction and characterization. Industrial Crops and Products 34, 1401-9. http://www.sciencedirect.com/science/article/pii/S0926669011001233

Salem AZM Oral administration of leaf extracts to rumen liquid donor lambs modifies in vitro gas production of other tree leaves. Animal Feed Science and Technology. http://www.sciencedirect.com/science/article/pii/S0377840112002441

Salem AZM, Hassan AA, Khalil MS, Gado HM, Alsersy H and Simbaya J Effects of sun-drying and exogenous enzymes on nutrients intake, digestibility and nitrogen utilization in sheep fed Atriplex halimus foliages. Animal Feed Science and Technology 171, 128-35. http://www.sciencedirect.com/science/article/pii/S037784011100441X

Salem AZM, Robinson PH, LÓpez S, Gohar YM, Rojo R and Tinoco JL Sensitivity of sheep intestinal lactic acid bacteria to secondary compounds extracted from Acacia saligna leaves. Animal Feed Science and Technology 161, 85-93. http://www.sciencedirect.com/science/article/pii/S0377840110002415

San Martín R, Ndjoko K and Hostettmann K Novel molluscicide against Pomacea canaliculata based on quinoa (Chenopodium quinoa) saponins. Crop Protection 27, 310-9. http://www.sciencedirect.com/science/article/pii/S0261219407000701

Sanchez-Schmitz G and Levy O Development of Newborn and Infant Vaccines. Science Translational Medicine 3, 90ps27-. http://stm.sciencemag.org

Santos-MagalhĂŁes NS and Mosqueira VCF Nanotechnology applied to the treatment of malaria. Advanced Drug Delivery Reviews 62, 560-75. http://www.sciencedirect.com/science/article/pii/S0169409X09003652

Sanz Y, Rastmanesh R and Agostonic C Understanding the role of gut microbes and probiotics in obesity: How far are we? Pharmacological Research 69, 144-55. http://www.sciencedirect.com/science/article/pii/S1043661812002083

SchiÖtt Ăs, Larsson K, Manniche Sr, KalliomÄki S, Heydenreich AV, Dalsgaard K and Kirkby N Posintro™-HBsAg, a modified ISCOM including HBsAg, induces strong cellular and humoral responses. International Journal of Pharmaceutics 414, 312-20. http://www.sciencedirect.com/science/article/pii/S0378517311004406

Schiappacasse I, Nahuelhual L, VÁsquez F and EcheverrÍa C Assessing the benefits and costs of dryland forest restoration in central Chile. Journal of Environmental Management 97, 38-45. http://www.sciencedirect.com/science/article/pii/S0301479711004178

Schlesinger ME, King MJ, Sole KC and Davenport WG Chapter 17 - Electrowinning. In ‘Extractive Metallurgy of Copper (Fifth Edition)’. (Ed.^(Eds  pp. 349-72. (Elsevier: Oxford). http://www.sciencedirect.com/science/article/pii/B9780080967899100174

Schmatz R, Perreira LB, Stefanello N, Mazzanti C, Spanevello R, Gutierres J, Bagatini M, Martins CC, Abdalla FtH, Daci da Silva Serres J, Zanini D, Vieira JM, Cardoso AiM, Schetinger MR and Morsch VM Effects of resveratrol on biomarkers of oxidative stress and on the activity of delta aminolevulinic acid dehydratase in liver and kidney of streptozotocin-induced diabetic rats. Biochimie 94, 374-83. http://www.sciencedirect.com/science/article/pii/S0300908411003105

Schulz JJ, Cayuela L, Echeverria C, Salas J and Rey Benayas JMa Monitoring land cover change of the dryland forest landscape of Central Chile (1975–2008). Applied Geography 30, 436-47. http://www.sciencedirect.com/science/article/pii/S0143622809000885

Schulz JJ, Cayuela L, Rey-Benayas JM and Schröder B Factors influencing vegetation cover change in Mediterranean Central Chile (1975–2008). Applied Vegetation Science 14, 571-82. http://dx.doi.org/10.1111/j.1654-109X.2011.01135.x

Scopel M, dos Santos O, Frasson AP, Abraham W-R, Tasca T, Henriques AlT and Macedo AJ Anti-Trichomonas vaginalis activity of marine-associated fungi from the South Brazilian Coast. Experimental Parasitology 133, 211-6. http://www.sciencedirect.com/science/article/pii/S001448941200344X

Serabian MA, Huang Y and Gad SC Preclinical Safety Evaluation of Biopharmaceuticals. In ‘Pharmaceutical Sciences Encyclopedia’. (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470571224.pse191

Setten DCv and Werken Gvd Molecular structures of saponins from Quillaja saponaria Molina. Saponins used in traditional and modern medicine /, 185-93.

Shakarji RA, He Y and Gregory S Statistical analysis of the effect of operating parameters on acid mist generation in copper electrowinning. Hydrometallurgy 106, 113-8. http://www.sciencedirect.com/science/article/pii/S0304386X10003397

Sharp FA, Lavelle EC and Gad SC Discovery of Vaccine Adjuvants. In ‘Pharmaceutical Sciences Encyclopedia’. (Ed.^(Eds  pp. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9780470571224.pse438

Sieber R, Schobinger Rehberger B, Walther B and Editor-in-Chief:Â Â John WF Milk Lipids | Removal of Cholesterol from Dairy Products. In ‘Encyclopedia of Dairy Sciences (Second Edition)’. (Ed.^(Eds  pp. 734-40. (Academic Press: San Diego). http://www.sciencedirect.com/science/article/pii/B9780123744074003459

Silva Elipe MV Hyphenation of NMR with Other Analytical Separation Techniques. In ‘LC-NMR and Other Hyphenated NMR Techniques’. (Ed.^(Eds  pp. 143-78. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118135396.ch6

Silveira F, Cibulski SP, Varela AP, MarquÉs JM, Chabalgoity A, de Costa F, Yendo ACA, Gosmann G, Roehe PM, FernÁndez C and Ferreira F Quillaja brasiliensis saponins are less toxic than Quil A and have similar properties when used as an adjuvant for a viral antigen preparation. Vaccine 29, 9177-82. http://www.sciencedirect.com/science/article/pii/S0264410X11015945

Silveira F, Rossi S, Fernandez C, Gosmann G, Schenkel E and Ferreira F Alum-type adjuvant effect of non-haemolytic saponins purified from Ilex and Passiflora spp. Phytother Res 25, 1783-8.

Silveira F, Rossi S, Fernández C, Gosmann G, Schenkel E and Ferreira F Alum-type Adjuvant Effect of Non-haemolytic Saponins Purified from Ilex and Passiflora spp. Phytotherapy Research 25, 1783-8. http://dx.doi.org/10.1002/ptr.3454

Simpson MG 8 - Diversity and Classification of Flowering Plants: Eudicots. In ‘Plant Systematics (Second Edition)’. (Ed.^(Eds  pp. 275-448. (Academic Press: San Diego). http://www.sciencedirect.com/science/article/pii/B9780123743800500087

Singha S, Banerjee S and Chandra G Synergistic effect of Croton caudatus (fruits) and Tiliacora acuminata (flowers) extracts against filarial vector Culex quinquefasciatus. Asian Pacific Journal of Tropical Biomedicine 1, S159-S64. http://www.sciencedirect.com/science/article/pii/S2221169111601470

Singha S and Chandra G Mosquito larvicidal activity of some common spices and vegetable waste on Culex quinquefasciatus and Anopheles stephensi. Asian Pacific Journal of Tropical Medicine 4, 288-93. http://www.sciencedirect.com/science/article/pii/S1995764511600886

Spertini Fo, Audran Rg, Lurati F, Ofori-Anyinam O, Zysset Fdr, Vandepapelière P, Moris P, DemoitiÉ M-A, Mettens P, Vinals C, Vastiau I, Jongert E, Cohen J and Ballou WR The candidate tuberculosis vaccine Mtb72F/AS02 in PPD positive adults: A randomized controlled phase I/II study. Tuberculosis 93, 179-88. http://www.sciencedirect.com/science/article/pii/S1472979212001989

Stanimirova R, Marinova K, Tcholakova S, Denkov ND, Stoyanov S and Pelan E Surface rheology of saponin adsorption layers. Langmuir 27, 12486-98.

Stills HF, Mark AS, Karla A. Stevens and Ronald P. WilsonA2 - Mark A. Suckow KAS and Ronald PW Chapter 11 - Polyclonal Antibody Production. In ‘The Laboratory Rabbit, Guinea Pig, Hamster, and Other Rodents’. (Ed.^(Eds  pp. 259-74. (Academic Press: Boston). http://www.sciencedirect.com/science/article/pii/B9780123809209000110

Stoyanov CT, Boscardin SB, Deroubaix S, Barba-Spaeth G, Franco D, Nussenzweig RS, Nussenzweig M and Rice CM Immunogenicity and protective efficacy of a recombinant yellow fever vaccine against the murine malarial parasite Plasmodium yoelii. Vaccine 28, 4644-52. http://www.sciencedirect.com/science/article/pii/S0264410X10006079

Sun H, Chen L, Wang J, Wang K and Zhou J Structure–function relationship of the saponins from the roots of Platycodon grandiflorum for hemolytic and adjuvant activity. International Immunopharmacology 11, 2047-56. http://www.sciencedirect.com/science/article/pii/S1567576911003389

Sun Y, Liu J, Yu H and Gong C Isolation and evaluation of immunological adjuvant activities of saponins from the roots of Pulsatilla chinensis with less adverse reactions. International Immunopharmacology 10, 584-90. http://www.sciencedirect.com/science/article/pii/S1567576910000652

Tafalla C, Bøgwald J and Dalmo RA Adjuvants and immunostimulants in fish vaccines: Current knowledge and future perspectives. Fish & Shellfish Immunology. http://www.sciencedirect.com/science/article/pii/S1050464813000909

Talibi I, Askarne L, Boubaker H, Boudyach EH, Msanda F, Saadi B and Ait Ben Aoumar A Antifungal activity of some Moroccan plants against Geotrichum candidum, the causal agent of postharvest citrus sour rot. Crop Protection 35, 41-6. http://www.sciencedirect.com/science/article/pii/S0261219411004078

Tam KI and Roner MR Characterization of in vivo anti-rotavirus activities of saponin extracts from Quillaja saponaria Molina. Antiviral Res 90, 231-41.

Tan H-H and Martin P Management of End-Stage Liver Disease in Chronic Hepatitis B. Clinics in Liver Disease 14, 477-93. http://www.sciencedirect.com/science/article/pii/S1089326110000358

Tielemans CL, Vlasak J, Kosa D, Billiouw J-M, Verpooten GA, Mezei I, Ryba M, Peeters PC, Mat O, Jadoul MY, Polakovic V, Dhaene M, Treille S, Kuriyakose SO, Leyssen M, Houard SA and Surquin M Immunogenicity and safety of an investigational AS02v-adjuvanted hepatitis B vaccine in patients with renal insufficiency who failed to respond or to maintain antibody levels after prior vaccination: Results of two open, randomized, comparative trials. Vaccine 29, 1159-66. http://www.sciencedirect.com/science/article/pii/S0264410X10017470

Tomasula PM, Nutter DW and Steve LT Chapter 2 - Mitigation of Greenhouse Gas Emissions in the Production of Fluid Milk. In ‘Advances in Food and Nutrition Research’. (Ed.^(Eds  pp. 41-88. (Academic Press). http://www.sciencedirect.com/science/article/pii/B9780123859891000028

Turner TD, Karlsson L, Mapiye C, Rolland DC, Martinsson K and Dugan MER Dietary influence on the m. longissimus dorsi fatty acid composition of lambs in relation to protein source. Meat Science 91, 472-7. http://www.sciencedirect.com/science/article/pii/S0309174012000794

VÁzquez-ChagoyÁn JC, Gupta S, Garg NJ and Louis M. Weiss HBTaLVK Chapter 6 - Vaccine Development Against Trypanosoma cruzi and Chagas Disease. In ‘Advances in Parasitology’. (Ed.^(Eds  pp. 121-46. (Academic Press). http://www.sciencedirect.com/science/article/pii/B978012385863400006X

Van de Ven H, Vermeersch M, Matheeussen A, Vandervoort J, Weyenberg W, Apers S, Cos P, Maes L and Ludwig A PLGA nanoparticles loaded with the antileishmanial saponin β-aescin: Factor influence study and in vitro efficacy evaluation. International Journal of Pharmaceutics 420, 122-32. http://www.sciencedirect.com/science/article/pii/S0378517311007782

van Zijderveld SM, Dijkstra J, Perdok HB, Newbold JR and Gerrits WJJ Dietary inclusion of diallyl disulfide, yucca powder, calcium fumarate, an extruded linseed product, or medium-chain fatty acids does not affect methane production in lactating dairy cows. Journal of Dairy Science 94, 3094-104. http://www.sciencedirect.com/science/article/pii/S0022030211002967

Vasta V and Luciano G The effects of dietary consumption of plants secondary compounds on small ruminants’ products quality. Small Ruminant Research 101, 150-9. http://www.sciencedirect.com/science/article/pii/S0921448811003841

Vega-GÁLvez A, San MartÍN R, Sanders M, Miranda M and Lara E CHARACTERISTICS AND MATHEMATICAL MODELING OF CONVECTIVE DRYING OF QUINOA (CHENOPODIUM QUINOA WILLD.): INFLUENCE OF TEMPERATURE ON THE KINETIC PARAMETERS. Journal of Food Processing and Preservation 34, 945-63. http://dx.doi.org/10.1111/j.1745-4549.2009.00410.x

Velickova E, Winkelhausen E, Kuzmanova S, Alves VD and MoldĂŁo-Martins M Impact of chitosan-beeswax edible coatings on the quality of fresh strawberries (Fragaria ananassa cv Camarosa) under commercial storage conditions. LWT - Food Science and Technology. http://www.sciencedirect.com/science/article/pii/S0023643813000492

Villalba JJ, Provenza FD, K Clemensen A, Larsen R and Juhnke J Preference for diverse pastures by sheep in response to intraruminal administrations of tannins, saponins and alkaloids. Grass and Forage Science 66, 224-36. http://dx.doi.org/10.1111/j.1365-2494.2010.00779.x

Vinay T-N, Park C-S, Kim H-Y and Jung S-J Toxicity and dose determination of quillaja saponin, aluminum hydroxide and squalene in olive flounder (Paralichthys olivaceus). Veterinary Immunology and Immunopathology. http://www.sciencedirect.com/science/article/pii/S0165242713001128

Vlaminck J, Lopez-Aban J, Ruano AL, del Olmo E and Muro A Vaccination against Strongyloides venezuelensis with homologue antigens using new immunomodulators. J Parasitol 96, 643-7.

Wald A, Koelle DM, Fife K, Warren T, LeClair K, Chicz RM, Monks S, Levey DL, Musselli C and Srivastava PK Safety and immunogenicity of long HSV-2 peptides complexed with rhHsc70 in HSV-2 seropositive persons. Vaccine 29, 8520-9. http://www.sciencedirect.com/science/article/pii/S0264410X11014526

Wang P, Ownby S, Zhang Z, Yuan W and Li S Cytotoxicity and inhibition of DNA topoisomerase I of polyhydroxylated triterpenoids and triterpenoid glycosides. Bioorganic & Medicinal Chemistry Letters 20, 2790-6. http://www.sciencedirect.com/science/article/pii/S0960894X1000394X

Wang Q, Guo Z, Editors-in-Chief:Â Â Lew M and Hung-Wen L 6.04 - Carbohydrate Vaccines. In ‘Comprehensive Natural Products II’. (Ed.^(Eds  pp. 91-122. (Elsevier: Oxford). http://www.sciencedirect.com/science/article/pii/B9780080453828001222

Wang W and Singh M Selection of Optimal Adjuvants and Product Factors that Affect Vaccine Immunogenicity. In ‘Development of Vaccines’. (Ed.^(Eds  pp. 327-83. (John Wiley & Sons, Inc.). http://dx.doi.org/10.1002/9781118023648.ch13

Watson DS, Endsley AN and Huang L Design considerations for liposomal vaccines: Influence of formulation parameters on antibody and cell-mediated immune responses to liposome associated antigens. Vaccine 30, 2256-72. http://www.sciencedirect.com/science/article/pii/S0264410X12001089

Wayhs CAY, Manfredini V, Sitta A, Deon M, Ribas GS, Vanzin CS, Biancini GB, Nin McS, Barros HMT and Vargas CR Effects of insulin and clonazepam on DNA damage in diabetic rats submitted to the forced swimming test. Mutation Research/Genetic Toxicology and Environmental Mutagenesis 703, 187-90. http://www.sciencedirect.com/science/article/pii/S1383571810003086

Weng A, Jenett-Siems K, Schmieder P, Bachran D, Bachran C, GÖrick C, Thakur M, Fuchs H and Melzig MF A convenient method for saponin isolation in tumour therapy. Journal of Chromatography B 878, 713-8. http://www.sciencedirect.com/science/article/pii/S1570023210000425

Weniger BG and Papania MJ 61 - Alternative vaccine delivery methods. In ‘Vaccines (Sixth Edition)’. (Ed.^(Eds  pp. 1200-31. (W.B. Saunders: London). http://www.sciencedirect.com/science/article/pii/B978145570090500063X

Whitaker JA, Rouphael NG, Edupuganti S, Lai L and Mulligan MJ Strategies to increase responsiveness to hepatitis B vaccination in adults with HIV-1. The Lancet Infectious Diseases 12, 966-76. http://www.sciencedirect.com/science/article/pii/S1473309912702438

Williams AE Vaccination. In ‘Immunology’. (Ed.^(Eds  pp. 342-62. (John Wiley & Sons, Ltd). http://dx.doi.org/10.1002/9781119998648.ch17

Williams SRO, Moate PJ, Hannah MC, Ribaux BE, Wales WJ and Eckard RJ Background matters with the SF6 tracer method for estimating enteric methane emissions from dairy cows: A critical evaluation of the SF6 procedure. Animal Feed Science and Technology 170, 265-76. http://www.sciencedirect.com/science/article/pii/S0377840111003798

Wojciechowski K Surface activity of saponin from Quillaja bark at the air/water and oil/water interfaces. Colloids and Surfaces B: Biointerfaces 108, 95-102. http://www.sciencedirect.com/science/article/pii/S0927776513001288

Wojciechowski K, Kezwon A, Lewandowska J and Marcinkowski K Effect of β-casein on surface activity of Quillaja bark saponin at fluid/fluid interfaces. Food Hydrocolloids. http://www.sciencedirect.com/science/article/pii/S0268005X12002068

Wojciechowski K, Piotrowski M, Popielarz W and Sosnowski TR Short- and mid-term adsorption behaviour of Quillaja Bark Saponin and its mixtures with lysozyme. Food Hydrocolloids 25, 687-93. http://www.sciencedirect.com/science/article/pii/S0268005X10001451

Wulff EG, Zida E, Torp J and Lund OS Yucca schidigera extract: a potential biofungicide against seedborne pathogens of sorghum. Plant Pathology 61, 331-8. http://dx.doi.org/10.1111/j.1365-3059.2011.02517.x

Wursthorn K, Wedemeyer H and Manns MP Managing HBV in patients with impaired immunity. Gut 59, 1430-45. http://gut.bmj.com/cgi/content/abstract/59/10/1430

Xu M, Rinker M, McLeod KR and Harmon DL Yucca schidigera extract decreases in vitro methane production in a variety of forages and diets. Animal Feed Science and Technology 159, 18-26. http://www.sciencedirect.com/science/article/pii/S0377840110001732

Yang Q, Shi X, Gu Q, Zhao S, Shan Y and Xu G On-line two dimensional liquid chromatography/mass spectrometry for the analysis of triacylglycerides in peanut oil and mouse tissue. Journal of Chromatography B 895–896, 48-55. http://www.sciencedirect.com/science/article/pii/S1570023212001626

Yang W-Z, Bo T, Ji S, Qiao X, Guo D-A and Ye M Rapid chemical profiling of saponins in the flower buds of Panax notoginseng by integrating MCI gel column chromatography and liquid chromatography/mass spectrometry analysis. Food Chemistry 139, 762-9. http://www.sciencedirect.com/science/article/pii/S0308814613000757

Yang Y, Leser ME, Sher AA and McClements DJ Formation and stability of emulsions using a natural small molecule surfactant: Quillaja saponin (Q-Naturale®). Food Hydrocolloids 30, 589-96. http://www.sciencedirect.com/science/article/pii/S0268005X12001804

Yang Y and McClements DJ Encapsulation of vitamin E in edible emulsions fabricated using a natural surfactant. Food Hydrocolloids 30, 712-20. http://www.sciencedirect.com/science/article/pii/S0268005X1200197X

Yotova M, Krasteva I, Jenett-Siems K, Zdraveva P and Nikolov S Triterpenoids in Gypsophila trichotoma Wend. Phytochemistry Letters 5, 752-5. http://www.sciencedirect.com/science/article/pii/S1874390012001681

Yusuf RO, Noor ZZ, Abba AH, Hassan MAA and Din MFM Methane emission by sectors: A comprehensive review of emission sources and mitigation methods. Renewable and Sustainable Energy Reviews 16, 5059-70. http://www.sciencedirect.com/science/article/pii/S1364032112002663

ZÚñiga GE, Junqueira-Gonçalves MP, Pizarro M, Contreras R, Tapia A and Silva S Effect of ionizing energy on extracts of Quillaja saponaria to be used as an antimicrobial agent on irradiated edible coating for fresh strawberries. Radiation Physics and Chemistry 81, 64-9. http://www.sciencedirect.com/science/article/pii/S0969806X11002829

Zasada IA, Walters TW and Pinkerton JN Post-Plant Nematicides for the Control of Root Lesion Nematode in Red Raspberry. HortTechnology 20, 856-62. http://horttech.ashspublications.org/cgi/content/abstract/20/5/856

Zbrun MV, Zielinski GC, Piscitelli HC, Descarga C, Urbani LA, Defain Tesoriero MV and Hermida L Evaluation of anti-Moraxella bovis pili immunoglobulin-A in tears following intranasal vaccination of cattle. Research in Veterinary Science 93, 183-9. http://www.sciencedirect.com/science/article/pii/S0034528811001822

Zhang J, Cao W, Tian J, Yue R, Li L, Guo B, Shan L, Yu B and Zhang W Evaluation of novel saponins from Psammosilene tunicoides and their analogs as immunomodulators. International Immunopharmacology 14, 21-6. http://www.sciencedirect.com/science/article/pii/S1567576912001750

Zhang S-d, Soltis DE, Yang Y, Li D-z and Yi T-s Multi-gene analysis provides a well-supported phylogeny of Rosales. Molecular Phylogenetics and Evolution 60, 21-8. http://www.sciencedirect.com/science/article/pii/S1055790311001928

Zhang T, Yang C, Rupa P, Jiang B and Mine Y Inhibitory effects of Quillaja saponin on IgE-mediated degranulation of rat basophilic leukemia RBL-2H3 Cells. Journal of Functional Foods 4, 864-71. http://www.sciencedirect.com/science/article/pii/S1756464612000989

Zhao X, Fan Y, Wang D, Hu Y, Guo L, Ruan S, Zhang J and Yuan J Immunological adjuvant efficacy of glycyrrhetinic acid liposome against Newcastle disease vaccine. Vaccine 29, 9611-7. http://www.sciencedirect.com/science/article/pii/S0264410X11016902

Zhou W, Wang X, Chen C and Zhu L Enhanced soil washing of phenanthrene by a plant-derived natural biosurfactant, Sapindus saponin. Colloids and Surfaces A: Physicochemical and Engineering Aspects 425, 122-8. http://www.sciencedirect.com/science/article/pii/S0927775713001581

Zhou YY, Mao HL, Jiang F, Wang JK, Liu JX and McSweeney CS Inhibition of rumen methanogenesis by tea saponins with reference to fermentation pattern and microbial communities in Hu sheep. Animal Feed Science and Technology 166–167, 93-100. http://www.sciencedirect.com/science/article/pii/S037784011100126X

Zhou Z, Meng Q and Yu Z Effects of Methanogenic Inhibitors on Methane Production and Abundances of Methanogens and Cellulolytic Bacteria in In Vitro Ruminal Cultures. Appl. Envir. Microbiol. 77, 2634-9. http://aem.asm.org/cgi/content/abstract/77/8/2634

Zulpo DL, Headley SA, Biazzono L, da Cunha IAL, Igarashi M, de Barros LD, Taroda A, Cardim SrT, Bogado ALG, Navarro IT and Garcia JoL Oocyst shedding in cats vaccinated by the nasal and rectal routes with crude rhoptry proteins of Toxoplasma gondii. Experimental Parasitology 131, 223-30. http://www.sciencedirect.com/science/article/pii/S0014489412001245

 


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Grateful acknowledgment is made to the following: for plant names: Australian Plant Name Index, Australian National Herbarium http://www.anbg.gov.au/cpbr/databases/apni-search-full.html; ; The International Plant Names Index, Royal Botanic Gardens, Kew/Harvard University Herbaria/Australian National Herbarium http://www.ipni.org/index.html; Plants Database, United States Department of Agriculture, National Resources Conservation Service http://plants.usda.gov/;DJ Mabberley (1997) The Plant Book, Cambridge University Press (Second Edition); JH Wiersma and B Leon (1999) World Economic Plants, CRC Press; RJ Hnatiuk (1990) Census of Australian Vascular Plants, Australian Government Publishing Service; for information: Science Direct http://www.sciencedirect.com/; Wiley Online Library http://onlinelibrary.wiley.com/advanced/search; High Wire http://highwire.stanford.edu/cgi/search; Oxford Journals http://services.oxfordjournals.org/search.dtl; USDA National Agricultural Library http://agricola.nal.usda.gov/booleancube/booleancube_search_cit.html; for synonyms: The Plant List http://www.theplantlist.org/; for common names: http://en.wikipedia.org/wiki/Main_Page; etc.


All information is included in good faith but this website does not warrant or guarantee the accuracy of any information on these pages, nor does the website accept responsibility for any loss arising from the use of this information.  Views and opinions are those of the authors themselves.  Every effort has been made to respect copyright owners' rights. 


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